TABLE 2

Pattern recognition receptors and antiviral factors

GeneaRelative expression in:
SIVmac239-infected vs Δ5G-infected animalsSIVmac239-infected vs uninfected animalsΔ5G-infected vs uninfected animals
Fold changebP valueFold changeP valueFold changeP value
TLR42.792.00E−033.781.23E−04
TLR23.028.86E−04
TLR82.255.33E−04
BST21.339.49E−032.863.13E−062.141.97E−05
DDX60L2.932.22E−032.707.22E−05
TRIM222.271.09E−04
DDX601.711.01E−029.051.53E−075.311.55E−05
DDX582.235.01E−047.803.87E−103.506.24E−06
IFIH11.994.13E−036.121.45E−063.083.72E−06
TLR73.343.99E−047.406.13E−052.221.63E−02
TRIM211.572.67E−023.011.71E−04
TRIM141.937.59E−032.881.36E−04
TRIM53.604.72E−042.441.05E−03
MYD882.332.80E−042.181.22E−03
APOBEC3H1.363.74E−023.324.13E−062.445.26E−06
APOBEC3B5.617.51E−074.298.11E−05
APOBEC3G4.861.10E−053.732.02E−05
APOBEC3A17.031.85E−0612.674.02E−05
TRIM692.062.06E−02
Avg1.934.803.88
  • a All genes belonged to group 3 as determined from hierarchical clustering analyses of transcriptome analysis data (Fig. 2B).

  • b Fold changes between two groups with statistically significant differences (P < 0.05) are shown.