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Vaccines and Antiviral Agents

The High Content of Fructose in Human Semen Competitively Inhibits Broad and Potent Antivirals that Target High-mannose Glycans

Jacklyn Johnson, Manuel G. Flores, John Rosa, Changze Han, Alicia M. Salvi, Kris A. DeMali, Jennifer R. Jagnow, Amy Sparks, Hillel Haim
Jacklyn Johnson
1 Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA USA.
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Manuel G. Flores
1 Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA USA.
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John Rosa
1 Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA USA.
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Changze Han
1 Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA USA.
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Alicia M. Salvi
2 Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA USA.
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Kris A. DeMali
2 Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA USA.
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Jennifer R. Jagnow
3 In Vitro Fertilization and Reproductive Testing Laboratory, University of Iowa Hospitals and Clinics, Iowa City, IA USA.
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Amy Sparks
3 In Vitro Fertilization and Reproductive Testing Laboratory, University of Iowa Hospitals and Clinics, Iowa City, IA USA.
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Hillel Haim
1 Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA USA.
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  • For correspondence: Hillel-haim@uiowa.edu
DOI: 10.1128/JVI.01749-19
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Article Information

DOI 
https://doi.org/10.1128/JVI.01749-19
PubMed 
32102878

Published By 
American Society for Microbiology Journals
History 
  • Published online February 26, 2020.

Copyright & Usage 
Copyright © 2020 American Society for Microbiology. All Rights Reserved.

Article Versions

  • You are currently viewing an Accepted Manuscript version of this article (February 26, 2020).
  • View the most recent version of this article

Author Information

  1. Jacklyn Johnson1,
  2. Manuel G. Flores1,
  3. John Rosa1,
  4. Changze Han1,
  5. Alicia M. Salvi2,
  6. Kris A. DeMali2,
  7. Jennifer R. Jagnow3,
  8. Amy Sparks3 and
  9. Hillel Haim1#
  1. 1 Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA USA.
  2. 2 Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA USA.
  3. 3 In Vitro Fertilization and Reproductive Testing Laboratory, University of Iowa Hospitals and Clinics, Iowa City, IA USA.
  • ↵# To whom correspondence should be addressed: Hillel Haim, MD, PhD, Department of Microbiology and Immunology, The University of Iowa, 51 Newton Rd, 3-770 BSB, Iowa City Iowa 52242, Phone: (319) 335-9989, Fax: (319) 335-9006, Email: Hillel-haim{at}uiowa.edu

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Mar 2020342018
Apr 20204113117
May 2020143108
Jun 202023124
Jul 20209695
Aug 20203553
Sep 20203958
Oct 202023167
Nov 202074421
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The High Content of Fructose in Human Semen Competitively Inhibits Broad and Potent Antivirals that Target High-mannose Glycans
Jacklyn Johnson, Manuel G. Flores, John Rosa, Changze Han, Alicia M. Salvi, Kris A. DeMali, Jennifer R. Jagnow, Amy Sparks, Hillel Haim
Journal of Virology Feb 2020, JVI.01749-19; DOI: 10.1128/JVI.01749-19

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The High Content of Fructose in Human Semen Competitively Inhibits Broad and Potent Antivirals that Target High-mannose Glycans
Jacklyn Johnson, Manuel G. Flores, John Rosa, Changze Han, Alicia M. Salvi, Kris A. DeMali, Jennifer R. Jagnow, Amy Sparks, Hillel Haim
Journal of Virology Feb 2020, JVI.01749-19; DOI: 10.1128/JVI.01749-19
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