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Genetic Diversity and Evolution

Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption

Line K. Vibholm, Julio C. C. Lorenzi, Joy A. Pai, Yehuda Z. Cohen, Thiago Y. Oliveira, John P. Barton, Marco Garcia Noceda, Ching-Lan Lu, Yuria Ablanedo-Terrazas, Perla M. Del Rio Estrada, Gustavo Reyes-Teran, Martin Tolstrup, Paul W. Denton, Tine Damsgaard, Ole S. Søgaard, Michel C. Nussenzweig
Guido Silvestri, Editor
Line K. Vibholm
aDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark
bDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
cLaboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA
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Julio C. C. Lorenzi
cLaboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA
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Joy A. Pai
cLaboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA
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Yehuda Z. Cohen
cLaboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA
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Thiago Y. Oliveira
cLaboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA
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John P. Barton
dDepartment of Physics and Astronomy, University of California, Riverside, California, USA
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Marco Garcia Noceda
dDepartment of Physics and Astronomy, University of California, Riverside, California, USA
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Ching-Lan Lu
cLaboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA
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Yuria Ablanedo-Terrazas
eCenter for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico
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Perla M. Del Rio Estrada
eCenter for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico
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Gustavo Reyes-Teran
eCenter for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico
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Martin Tolstrup
aDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark
bDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
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Paul W. Denton
aDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark
bDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
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Tine Damsgaard
aDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark
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Ole S. Søgaard
aDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark
bDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
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Michel C. Nussenzweig
cLaboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA
fHoward Hughes Medical Institute, The Rockefeller University, New York, New York, USA
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Guido Silvestri
Emory University
Roles: Editor
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DOI: 10.1128/JVI.01920-18
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Article Information

DOI 
https://doi.org/10.1128/JVI.01920-18
PubMed 
30700598

Published By 
American Society for Microbiology Journals
History 
  • Received November 5, 2018
  • Accepted December 23, 2018
  • Published online April 3, 2019.

Copyright & Usage 
Copyright © 2019 Vibholm et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Guido Silvestri, Editor, Emory University

Article Versions

  • Accepted Manuscript version (January 30, 2019).
  • You are viewing the most recent version of this article.

Author Information

  1. Line K. Vibholma,b,c*,
  2. Julio C. C. Lorenzic,
  3. Joy A. Paic,
  4. Yehuda Z. Cohenc,
  5. Thiago Y. Oliveirac,
  6. John P. Bartond,
  7. Marco Garcia Nocedad,
  8. Ching-Lan Luc,
  9. Yuria Ablanedo-Terrazase,
  10. Perla M. Del Rio Estradae,
  11. Gustavo Reyes-Terane,
  12. Martin Tolstrupa,b,
  13. Paul W. Dentona,b,
  14. Tine Damsgaarda,
  15. Ole S. Søgaarda,b and
  16. Michel C. Nussenzweigc,f
  1. aDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark
  2. bDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
  3. cLaboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA
  4. dDepartment of Physics and Astronomy, University of California, Riverside, California, USA
  5. eCenter for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico
  6. fHoward Hughes Medical Institute, The Rockefeller University, New York, New York, USA
  • Address correspondence to Michel C. Nussenzweig, nussen{at}rockefeller.edu.
  • ↵* Present address: Line K. Vibholm, Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.

  • Citation Vibholm LK, Lorenzi JCC, Pai JA, Cohen YZ, Oliveira TY, Barton JP, Garcia Noceda M, Lu C-L, Ablanedo-Terrazas Y, Del Rio Estrada PM, Reyes-Teran G, Tolstrup M, Denton PW, Damsgaard T, Søgaard OS, Nussenzweig MC. 2019. Characterization of intact proviruses in blood and lymph node from HIV-infected individuals undergoing analytical treatment interruption. J Virol 93:e01920-18. https://doi.org/10.1128/JVI.01920-18.

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Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption
Line K. Vibholm, Julio C. C. Lorenzi, Joy A. Pai, Yehuda Z. Cohen, Thiago Y. Oliveira, John P. Barton, Marco Garcia Noceda, Ching-Lan Lu, Yuria Ablanedo-Terrazas, Perla M. Del Rio Estrada, Gustavo Reyes-Teran, Martin Tolstrup, Paul W. Denton, Tine Damsgaard, Ole S. Søgaard, Michel C. Nussenzweig
Journal of Virology Apr 2019, 93 (8) e01920-18; DOI: 10.1128/JVI.01920-18

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Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption
Line K. Vibholm, Julio C. C. Lorenzi, Joy A. Pai, Yehuda Z. Cohen, Thiago Y. Oliveira, John P. Barton, Marco Garcia Noceda, Ching-Lan Lu, Yuria Ablanedo-Terrazas, Perla M. Del Rio Estrada, Gustavo Reyes-Teran, Martin Tolstrup, Paul W. Denton, Tine Damsgaard, Ole S. Søgaard, Michel C. Nussenzweig
Journal of Virology Apr 2019, 93 (8) e01920-18; DOI: 10.1128/JVI.01920-18
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    • ABSTRACT
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KEYWORDS

ATI
HIV-1
infectious diseases
recombination
lymph node

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