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Pathogenesis and Immunity

Comprehensive Mutagenesis of Herpes Simplex Virus 1 Genome Identifies UL42 as an Inhibitor of Type I Interferon Induction

Maxime Chapon, Kislay Parvatiyar, Saba Roghiyh Aliyari, Jeffrey S. Zhao, Genhong Cheng
Jae U. Jung, Editor
Maxime Chapon
aDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
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Kislay Parvatiyar
aDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
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Saba Roghiyh Aliyari
aDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
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Jeffrey S. Zhao
aDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
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Genhong Cheng
aDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
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Jae U. Jung
University of Southern California
Roles: Editor
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DOI: 10.1128/JVI.01446-19
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Article Information

DOI 
https://doi.org/10.1128/JVI.01446-19
PubMed 
31511375

Published By 
American Society for Microbiology Journals
History 
  • Received August 26, 2019
  • Accepted September 2, 2019
  • Published online November 13, 2019.

Copyright & Usage 
Copyright © 2019 American Society for Microbiology. All Rights Reserved.
Editors and / or Reviewers 
  • Jae U. Jung, Editor, University of Southern California

Article Versions

  • Accepted Manuscript version (September 11, 2019).
  • You are viewing the most recent version of this article.

Author Information

  1. Maxime Chapona,
  2. Kislay Parvatiyara*,
  3. Saba Roghiyh Aliyaria,
  4. Jeffrey S. Zhaoa and
  5. Genhong Chenga
  1. aDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
  • Address correspondence to Genhong Cheng, gcheng{at}mednet.ucla.edu.
  • ↵* Present address: Kislay Parvatiyar, Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, Louisiana, USA

  • Citation Chapon M, Parvatiyar K, Aliyari SR, Zhao JS, Cheng G. 2019. Comprehensive mutagenesis of herpes simplex virus 1 genome identifies UL42 as an inhibitor of type I interferon induction. J Virol 93:e01446-19. https://doi.org/10.1128/JVI.01446-19.

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Comprehensive Mutagenesis of Herpes Simplex Virus 1 Genome Identifies UL42 as an Inhibitor of Type I Interferon Induction
Maxime Chapon, Kislay Parvatiyar, Saba Roghiyh Aliyari, Jeffrey S. Zhao, Genhong Cheng
Journal of Virology Nov 2019, 93 (23) e01446-19; DOI: 10.1128/JVI.01446-19

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Comprehensive Mutagenesis of Herpes Simplex Virus 1 Genome Identifies UL42 as an Inhibitor of Type I Interferon Induction
Maxime Chapon, Kislay Parvatiyar, Saba Roghiyh Aliyari, Jeffrey S. Zhao, Genhong Cheng
Journal of Virology Nov 2019, 93 (23) e01446-19; DOI: 10.1128/JVI.01446-19
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KEYWORDS

HSV-1
IRF-3
UL42
interferon

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