Cover photograph: In this issue, Henry et al. demonstrated that Flublok (a recombinant HA vaccine) and Flucelvax (a mammalian cell-grown vaccine) are similarly immunogenic but may differ in the preferences of the elicited antibodies for the receptor-binding domain on the HA head (yellow). The frequencies of antibodies targeting conserved epitopes on the HA stalk domain (white) were similar for both vaccines. (See related article at e01150-19.) (Copyright © 2019 American Society for Microbiology. All Rights Reserved.)