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Journal of Virology
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Journal Cover & Description

October 2019; Volume 93,Issue 20

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Cover photograph: Rotavirus genome replication, packaging of virus genome segments in viral cores, and double-layered particle (DLP) formation take place in membraneless cytosolic inclusions called viroplasms. DLPs bud from viroplasms to the rough endoplasmic reticulum (RER) to become mature triple-layered particles (TLPs). During this process, a transient lipidic membrane surrounds immature TLPs. The image represents high-definition transmission electron microscopy of a viroplasm (blue) at 6 h postinfection surrounded by RER (green) containing TLPs (red). After glutaraldehyde fixation, samples were stained with osmium tetroxide and potassium ferrocyanide. Acquired images were colored using Adobe Photoshop. (See related article in October 2019, vol. 93, no. 19, e01062-19.) (Copyright © 2019 American Society for Microbiology. All Rights Reserved.)

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Journal of Virology: 93 (20)

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volume 93, issue 20
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  • Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus
  • COVID-19 Vaccines: “Warp Speed” Needs Mind Melds, Not Warped Minds
  • Nucleocapsid Protein Recruitment to Replication-Transcription Complexes Plays a Crucial Role in Coronaviral Life Cycle
  • Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry
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