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Structure and Assembly

Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection

Kun-Wei Chan, Ruimin Pan, Matthew Costa, Miroslaw K. Gorny, Shixia Wang, Shan Lu, Xiang-Peng Kong
Wesley I. Sundquist, Editor
Kun-Wei Chan
aDepartment of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York, New York, USA
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Ruimin Pan
aDepartment of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York, New York, USA
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Matthew Costa
bDepartment of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
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Miroslaw K. Gorny
cDepartment of Pathology, NYU School of Medicine, New York, New York, USA
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Shixia Wang
bDepartment of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
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Shan Lu
bDepartment of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
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Xiang-Peng Kong
aDepartment of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York, New York, USA
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Wesley I. Sundquist
University of Utah
Roles: Editor
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DOI: 10.1128/JVI.00641-18
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Article Information

DOI 
https://doi.org/10.1128/JVI.00641-18
PubMed 
29997214

Published By 
American Society for Microbiology Journals
History 
  • Received April 14, 2018
  • Accepted June 30, 2018
  • Published online August 29, 2018.

Copyright & Usage 
Copyright © 2018 American Society for Microbiology. All Rights Reserved.
Editors and / or Reviewers 
  • Wesley I. Sundquist, Editor, University of Utah

Article Versions

  • Accepted Manuscript version (July 11, 2018).
  • You are viewing the most recent version of this article.

Author Information

  1. Kun-Wei Chana,
  2. Ruimin Pana,
  3. Matthew Costab,
  4. Miroslaw K. Gornyc,
  5. Shixia Wangb,
  6. Shan Lub and
  7. Xiang-Peng Konga
  1. aDepartment of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York, New York, USA
  2. bDepartment of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
  3. cDepartment of Pathology, NYU School of Medicine, New York, New York, USA

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Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection
Kun-Wei Chan, Ruimin Pan, Matthew Costa, Miroslaw K. Gorny, Shixia Wang, Shan Lu, Xiang-Peng Kong
Journal of Virology Aug 2018, 92 (18) e00641-18; DOI: 10.1128/JVI.00641-18

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Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection
Kun-Wei Chan, Ruimin Pan, Matthew Costa, Miroslaw K. Gorny, Shixia Wang, Shan Lu, Xiang-Peng Kong
Journal of Virology Aug 2018, 92 (18) e00641-18; DOI: 10.1128/JVI.00641-18
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    • ABSTRACT
    • INTRODUCTION
    • RESULTS
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KEYWORDS

HIV-1
gp120
V3 loop
affinity maturation
V3
antibody
gene usage
structure

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