Table of Contents
Spotlight
Structure and Assembly
Genome Replication and Regulation of Viral Gene Expression
Genome Replication and Regulation of Viral Gene ExpressionUpregulation of MicroRNA 711 Mediates HIV-1 Vpr Promotion of Kaposi's Sarcoma-Associated Herpesvirus Latency and Induction of Pro-proliferation and Pro-survival Cytokines by Targeting the Notch/NF-κB-Signaling Axis
Genome Replication and Regulation of Viral Gene Expression | SpotlightMurine Cytomegalovirus Protein pM91 Interacts with pM79 and Is Critical for Viral Late Gene Expression
Genome Replication and Regulation of Viral Gene ExpressionPARP1 Stabilizes CTCF Binding and Chromatin Structure To Maintain Epstein-Barr Virus Latency Type
Genome Replication and Regulation of Viral Gene ExpressionThe 5′ Untranslated Region of the Capsid Protein 2 Gene of Mink Enteritis Virus Is Essential for Its Expression
Genome Replication and Regulation of Viral Gene Expression | SpotlightIn Vivo Labelling of Adenovirus DNA Identifies Chromatin Anchoring and Biphasic Genome Replication
Genome Replication and Regulation of Viral Gene ExpressionAdenovirus E1A Activation Domain Regulates H3 Acetylation Affecting Varied Steps in Transcription at Different Viral Promoters
Genetic Diversity and Evolution
Genetic Diversity and EvolutionHepacivirus A Infection in Horses Defines Distinct Envelope Hypervariable Regions and Elucidates Potential Roles of Viral Strain and Adaptive Immune Status in Determining Envelope Diversity and Infection OutcomeHepacivirus C (hepatitis C virus) is estimated to infect 150 million people worldwide and is a leading cause of cirrhosis and hepatocellular carcinoma. In contrast, its closest relative, hepacivirus A, causes relatively mild disease in horses and is frequently cleared. The relationship between quasispecies evolution and infection outcome has not been explored for hepacivirus A. To address this knowledge gap, we examined envelope gene...
Virus-Cell Interactions
Virus-Cell InteractionsBub1 Facilitates Virus Entry through Endocytosis in a Model of Drosophila Pathogenesis
Virus-Cell InteractionsTransduction with Lentiviral Vectors Altered the Expression Profile of Host MicroRNAs
Virus-Cell InteractionsGallid Herpesvirus 1 Initiates Apoptosis in Uninfected Cells through Paracrine Repression of p53
Virus-Cell Interactions | SpotlightReal-Time Visualization and Quantification of Human Cytomegalovirus Replication in Living Cells Using the ANCHOR DNA Labeling Technology
Virus-Cell Interactions | SpotlightGeminivirus Replication Protein Impairs SUMO Conjugation of Proliferating Cellular Nuclear Antigen at Two Acceptor Sites
Virus-Cell InteractionsEpstein-Barr Virus Nuclear Antigen 3C Facilitates Cell Proliferation by Regulating Cyclin D2
Virus-Cell Interactions | SpotlightAncient Evolutionary Origin and Positive Selection of the Retroviral Restriction Factor Fv1 in Muroid Rodents
Cellular Response to Infection
Cellular Response to InfectionEquine Myxovirus Resistance Protein 2 Restricts Lentiviral Replication by Blocking Nuclear Uptake of Capsid Protein
Transformation and Oncogenesis
Transformation and OncogenesisModified Anoikis Assay That Functionally Segregates Epstein-Barr Virus LMP1 Strains into Two Groups
Prions
Vaccines and Antiviral Agents
Vaccines and Antiviral AgentsTargeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of EntryBroadly neutralizing antibodies (bNAbs) prevent HIV infection in monkey challenge models and suppress HIV replication in infected humans. Combinations of bNAbs are more effective at suppression, and antibody-like molecules engineered to have two or three bNAb combining sites also inhibit HIV replication in monkeys and other animal models. To expand the available array of multispecific HIV inhibitors, we designed single-component...
Vaccines and Antiviral AgentsProbing Zika Virus Neutralization Determinants with Glycoprotein Mutants Bearing Linear Epitope Insertions
Vaccines and Antiviral AgentsEngineered Dengue Virus Domain III Proteins Elicit Cross-Neutralizing Antibody Responses in Mice
Pathogenesis and Immunity
Pathogenesis and ImmunitySimian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus MacaquesWhile antiretroviral therapy (ART) can reduce HIV replication, the virus cannot be eradicated from an infected individual, and our incomplete understanding of HIV persistence in reservoirs greatly complicates the generation of a cure for HIV infection. Given the immaturity of the infant immune system, it is critically important to study HIV reservoirs specifically in this population. Here, we established a pediatric animal model to...
Masthead
