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Transformation and Oncogenesis

Epstein-Barr Virus Latent Membrane Protein 1 Induces Cancer Stem/Progenitor-Like Cells in Nasopharyngeal Epithelial Cell Lines

Satoru Kondo, Naohiro Wakisaka, Masamichi Muramatsu, Yoh Zen, Kazuhira Endo, Shigeyuki Murono, Hisashi Sugimoto, Shoji Yamaoka, Joseph S. Pagano, Tomokazu Yoshizaki
Satoru Kondo
1Division of Otolaryngology, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
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Naohiro Wakisaka
1Division of Otolaryngology, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
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Masamichi Muramatsu
2Department of Molecular Genetics, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
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Yoh Zen
3Division of Human Pathology, Graduate School of Medicine, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
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Kazuhira Endo
1Division of Otolaryngology, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
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Shigeyuki Murono
1Division of Otolaryngology, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
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Hisashi Sugimoto
1Division of Otolaryngology, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
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Shoji Yamaoka
4Department of Molecular Virology, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo, Tokyo 113-8519, Japan
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Joseph S. Pagano
5Lineberger Comprehensive Cancer Center and Departments of Medicine and Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295
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Tomokazu Yoshizaki
1Division of Otolaryngology, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
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  • For correspondence: tomoy@med.kanazawa-u.ac.jp
DOI: 10.1128/JVI.00188-11
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Article Information

DOI 
https://doi.org/10.1128/JVI.00188-11
PubMed 
21849440

Published By 
American Society for Microbiology Journals
History 
  • Received January 27, 2011
  • Accepted August 9, 2011
  • Published online October 6, 2011.

Copyright & Usage 
Copyright © 2011, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (August 17, 2011).
  • You are viewing the most recent version of this article.

Author Information

  1. Satoru Kondo1†,
  2. Naohiro Wakisaka1†,
  3. Masamichi Muramatsu2,
  4. Yoh Zen3,
  5. Kazuhira Endo1,
  6. Shigeyuki Murono1,
  7. Hisashi Sugimoto1,
  8. Shoji Yamaoka4,
  9. Joseph S. Pagano5 and
  10. Tomokazu Yoshizaki1*
  1. 1Division of Otolaryngology, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
  2. 2Department of Molecular Genetics, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
  3. 3Division of Human Pathology, Graduate School of Medicine, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640
  4. 4Department of Molecular Virology, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo, Tokyo 113-8519, Japan
  5. 5Lineberger Comprehensive Cancer Center and Departments of Medicine and Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295
  • ↵* Corresponding author. Mailing address: Division of Otolaryngology, Graduate School of Medicine, Kanazawa University, Kanazawa, Ishikawa 920-8640, Japan. Phone: 81-76-265-2413. Fax: 81-76-234-4265. E-mail: tomoy{at}med.kanazawa-u.ac.jp.
  • ↵† S.K. and N.W. contributed equally to this work.

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Epstein-Barr Virus Latent Membrane Protein 1 Induces Cancer Stem/Progenitor-Like Cells in Nasopharyngeal Epithelial Cell Lines
Satoru Kondo, Naohiro Wakisaka, Masamichi Muramatsu, Yoh Zen, Kazuhira Endo, Shigeyuki Murono, Hisashi Sugimoto, Shoji Yamaoka, Joseph S. Pagano, Tomokazu Yoshizaki
Journal of Virology Oct 2011, 85 (21) 11255-11264; DOI: 10.1128/JVI.00188-11

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Epstein-Barr Virus Latent Membrane Protein 1 Induces Cancer Stem/Progenitor-Like Cells in Nasopharyngeal Epithelial Cell Lines
Satoru Kondo, Naohiro Wakisaka, Masamichi Muramatsu, Yoh Zen, Kazuhira Endo, Shigeyuki Murono, Hisashi Sugimoto, Shoji Yamaoka, Joseph S. Pagano, Tomokazu Yoshizaki
Journal of Virology Oct 2011, 85 (21) 11255-11264; DOI: 10.1128/JVI.00188-11
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