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Virus-Cell Interactions

Human Cytomegalovirus pUL83 Stimulates Activity of the Viral Immediate-Early Promoter through Its Interaction with the Cellular IFI16 Protein

Ileana M. Cristea, Nathaniel J. Moorman, Scott S. Terhune, Christian D. Cuevas, Erin S. O'Keefe, Michael P. Rout, Brian T. Chait, Thomas Shenk
Ileana M. Cristea
1Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544-1014
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Nathaniel J. Moorman
1Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544-1014
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Scott S. Terhune
2Microbiology and Molecular Genetics and Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226
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Christian D. Cuevas
1Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544-1014
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Erin S. O'Keefe
1Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544-1014
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Michael P. Rout
3Laboratory of Cellular and Structural Biology
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Brian T. Chait
4Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, Rockefeller University, New York, New York 10021
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Thomas Shenk
1Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544-1014
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  • For correspondence: tshenk@princeton.edu
DOI: 10.1128/JVI.00139-10
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Article Information

DOI 
https://doi.org/10.1128/JVI.00139-10
PubMed 
20504932

Published By 
American Society for Microbiology Journals
History 
  • Received January 21, 2010
  • Accepted May 17, 2010
  • Published online July 2, 2010.

Copyright & Usage 
Copyright © 2010 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (May 26, 2010).
  • You are viewing the most recent version of this article.

Author Information

  1. Ileana M. Cristea1†,
  2. Nathaniel J. Moorman1†,
  3. Scott S. Terhune2†,
  4. Christian D. Cuevas1,
  5. Erin S. O'Keefe1,
  6. Michael P. Rout3,
  7. Brian T. Chait4 and
  8. Thomas Shenk1*
  1. 1Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544-1014
  2. 2Microbiology and Molecular Genetics and Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226
  3. 3Laboratory of Cellular and Structural Biology
  4. 4Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, Rockefeller University, New York, New York 10021
  • ↵† These authors contributed equally to this work.

  • ↵* Corresponding author. Mailing address: Department of Molecular Biology, Princeton University, Lewis Thomas Laboratory, Washington Road, Princeton, New Jersey 08544-1014. Phone: (609) 258-5992. Fax: (609) 258-1704. E-mail: tshenk{at}princeton.edu
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Human Cytomegalovirus pUL83 Stimulates Activity of the Viral Immediate-Early Promoter through Its Interaction with the Cellular IFI16 Protein
Ileana M. Cristea, Nathaniel J. Moorman, Scott S. Terhune, Christian D. Cuevas, Erin S. O'Keefe, Michael P. Rout, Brian T. Chait, Thomas Shenk
Journal of Virology Jul 2010, 84 (15) 7803-7814; DOI: 10.1128/JVI.00139-10

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Human Cytomegalovirus pUL83 Stimulates Activity of the Viral Immediate-Early Promoter through Its Interaction with the Cellular IFI16 Protein
Ileana M. Cristea, Nathaniel J. Moorman, Scott S. Terhune, Christian D. Cuevas, Erin S. O'Keefe, Michael P. Rout, Brian T. Chait, Thomas Shenk
Journal of Virology Jul 2010, 84 (15) 7803-7814; DOI: 10.1128/JVI.00139-10
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KEYWORDS

cytomegalovirus
Genes, Immediate-Early
host-pathogen interactions
Nuclear Proteins
Phosphoproteins
Promoter Regions, Genetic
transcriptional activation
Viral Matrix Proteins

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