DOI: 10.1128/JVI.00213-09
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History
- Received January 29, 2009
- Accepted March 24, 2009
- Published online May 20, 2009.
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Copyright © 2009 American Society for Microbiology
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- Accepted Manuscript version (April 01, 2009).
- You are viewing the most recent version of this article.
Author Information
- Program in Genetics and Department of Molecular Microbiology and Immunology, University of Missouri—Columbia School of Medicine, Life Sciences Center, Columbia, Missouri 65211
- ↵* Corresponding author. Mailing address: 471f Life Sciences Center, University of Missouri—Columbia, 1201 Rollins Rd., Columbia, MO 65211. Phone: (573) 882-3920. Fax: (573) 884-9676. E-mail: pinteld{at}missouri.edu
↵† Present address: Gene Therapy Center, University of North Carolina—Chapel Hill, Chapel Hill, NC 27599-7352.
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- ABSTRACT
- U- and A-rich intronic sequences immediately downstream of the 5′ splice site of the large intron are required for its efficient excision.
- The activity of the ISE is distance dependent.
- TIA-1 and TIAR are important for the efficient use of the MVM nonconsensus large-intron donor.
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