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Table of Contents

October 15, 2008; Volume 82,Issue 20

Spotlight

  • Free
    Spotlight
    Articles of Significant Interest Selected from This Issue by the Editors

Pathogenesis and Immunity

  • Pathogenesis and Immunity
    Impaired Hepatitis C Virus (HCV)-Specific Effector CD8+ T Cells Undergo Massive Apoptosis in the Peripheral Blood during Acute HCV Infection and in the Liver during the Chronic Phase of Infection
    Henry Radziewicz, Chris C. Ibegbu, Huiming Hon, Melissa K. Osborn, Kamil Obideen, Mohammad Wehbi, Gordon J. Freeman, Jeffrey L. Lennox, Kimberly A. Workowski, Holly L. Hanson, Arash Grakoui
  • Pathogenesis and Immunity
    Murine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia
    Jessica K. Roth-Cross, Susan J. Bender, Susan R. Weiss
  • Pathogenesis and Immunity
    Lymphoid-Related CD11c+ CD8α+ Dendritic Cells Are Involved in Enhancing Herpes Simplex Virus Type 1 Latency
    Kevin R. Mott, David UnderHill, Steven L. Wechsler, Homayon Ghiasi
  • Pathogenesis and Immunity
    CD20, CD3, and CD40 Ligand Microclusters Segregate Three-Dimensionally In Vivo at B-Cell-T-Cell Immunological Synapses after Viral Immunity in Primate Brain
    Carlos Barcia, Aurora Gomez, Vicente de Pablos, Emiliano Fernández-Villalba, Chunyan Liu, Kurt M. Kroeger, Javier Martín, Andrés Fernández Barreiro, Maria G. Castro, Pedro R. Lowenstein, Maria-Trinidad Herrero
  • Pathogenesis and Immunity
    Neonatal Neural Progenitor Cells and Their Neuronal and Glial Cell Derivatives Are Fully Permissive for Human Cytomegalovirus Infection
    Min Hua Luo, Philip H. Schwartz, Elizabeth A. Fortunato
  • Pathogenesis and Immunity | Spotlight
    Early Interferon Therapy for Hepatitis C Virus Infection Rescues Polyfunctional, Long-Lived CD8+ Memory T Cells
    Gamal Badr, Nathalie Bédard, Mohamed S. Abdel-Hakeem, Lydie Trautmann, Bernard Willems, Jean-Pierre Villeneuve, Elias K. Haddad, Rafick P. Sékaly, Julie Bruneau, Naglaa H. Shoukry
  • Pathogenesis and Immunity
    Oseltamivir-Resistant Influenza A Viruses Are Transmitted Efficiently among Guinea Pigs by Direct Contact but Not by Aerosol
    Nicole M. Bouvier, Anice C. Lowen, Peter Palese
  • Pathogenesis and Immunity
    Vaccinia Virus Encodes I5, a Small Hydrophobic Virion Membrane Protein That Enhances Replication and Virulence in Mice
    Cindy L. Sood, Jerrold M. Ward, Bernard Moss
  • Pathogenesis and Immunity
    Expansion of Human Cytomegalovirus (HCMV) Immediate-Early 1-Specific CD8+ T Cells and Control of HCMV Replication after Allogeneic Stem Cell Transplantation
    Karim Sacre, Stéphanie Nguyen, Claire Deback, Guislaine Carcelain, Jean-Paul Vernant, Véronique Leblond, Brigitte Autran, Nathalie Dhedin
  • Pathogenesis and Immunity | Spotlight
    Functions of Varicella-Zoster Virus ORF23 Capsid Protein in Viral Replication and the Pathogenesis of Skin Infection
    Vaishali Chaudhuri, Marvin Sommer, Jaya Rajamani, Leigh Zerboni, Ann M. Arvin
  • Pathogenesis and Immunity
    The Quality of Chimpanzee T-Cell Activation and Simian Immunodeficiency Virus/Human Immunodeficiency Virus Susceptibility Achieved via Antibody-Mediated T-Cell Receptor/CD3 Stimulation Is a Function of the Anti-CD3 Antibody Isotype
    Frederic Bibollet-Ruche, Brett A. McKinney, Alexandra Duverger, Frederic H. Wagner, Aftab A. Ansari, Olaf Kutsch
  • Pathogenesis and Immunity
    Regulatory Role of CD1d in Neurotropic Virus Infection
    Ikuo Tsunoda, Tomoko Tanaka, Robert S. Fujinami
  • Pathogenesis and Immunity
    Herpes Simplex Virus Type 2-Induced Mortality following Genital Infection Is Blocked by Anti-Tumor Necrosis Factor Alpha Antibody in CXCL10-Deficient Mice
    Manoj Thapa, Daniel J. J. Carr
  • Pathogenesis and Immunity
    In Vivo Competence of Murine Cytomegalovirus under the Control of the Human Cytomegalovirus Major Immediate-Early Enhancer in the Establishment of Latency and Reactivation
    Montse Gustems, Andreas Busche, Martin Messerle, Peter Ghazal, Ana Angulo
  • Pathogenesis and Immunity
    Fusion of Enhanced Green Fluorescent Protein to the Pseudorabies Virus Axonal Sorting Protein Us9 Blocks Anterograde Spread of Infection in Mammalian Neurons
    M. G. Lyman, D. Curanovic, A. D. Brideau, L. W. Enquist
  • Pathogenesis and Immunity
    Scrapie Resistance in ARQ Sheep
    W. W. Laegreid, M. L. Clawson, M. P. Heaton, B. T. Green, K. I. O'Rourke, D. P. Knowles

Genome Replication and Regulation of Viral Gene Expression

  • Genome Replication and Regulation of Viral Gene Expression
    Evolutionarily Conserved Function of a Viral MicroRNA
    G. J. Seo, L. H. L. Fink, B. O'Hara, W. J. Atwood, C. S. Sullivan
  • Genome Replication and Regulation of Viral Gene Expression
    NF-κB Signaling Differentially Regulates Influenza Virus RNA Synthesis
    Naveen Kumar, Zhong-tao Xin, Yuhong Liang, Hinh Ly, Yuying Liang
  • Genome Replication and Regulation of Viral Gene Expression
    Transactivation of Cellular Genes Involved in Nucleotide Metabolism by the Regulatory IE1 Protein of Murine Cytomegalovirus Is Not Critical for Viral Replicative Fitness in Quiescent Cells and Host Tissues
    Vanessa Wilhelmi, Christian O. Simon, Jürgen Podlech, Verena Böhm, Torsten Däubner, Simone Emde, Dennis Strand, Angélique Renzaho, Niels A. W. Lemmermann, Christof K. Seckert, Matthias J. Reddehase, Natascha K. A. Grzimek
  • Genome Replication and Regulation of Viral Gene Expression
    Block to the Production of Full-Length B19 Virus Transcripts by Internal Polyadenylation Is Overcome by Replication of the Viral Genome
    Wuxiang Guan, Fang Cheng, Yuko Yoto, Steve Kleiboeker, Susan Wong, Ning Zhi, David J. Pintel, Jianming Qiu
  • Genome Replication and Regulation of Viral Gene Expression
    Integration Site Preference of Xenotropic Murine Leukemia Virus-Related Virus, a New Human Retrovirus Associated with Prostate Cancer
    Sanggu Kim, Namshin Kim, Beihua Dong, David Boren, Serena A. Lee, Jaydip Das Gupta, Christina Gaughan, Eric A. Klein, Christopher Lee, Robert H. Silverman, Samson A. Chow
  • Genome Replication and Regulation of Viral Gene Expression
    Human Endogenous Retrovirus Family HERV-K(HML-2) RNA Transcripts Are Selectively Packaged into Retroviral Particles Produced by the Human Germ Cell Tumor Line Tera-1 and Originate Mainly from a Provirus on Chromosome 22q11.21
    Klemens Ruprecht, Humberto Ferreira, Aline Flockerzi, Silke Wahl, Marlies Sauter, Jens Mayer, Nikolaus Mueller-Lantzsch
  • Genome Replication and Regulation of Viral Gene Expression
    Different Types of nsP3-Containing Protein Complexes in Sindbis Virus-Infected Cells
    Rodion Gorchakov, Natalia Garmashova, Elena Frolova, Ilya Frolov
  • Genome Replication and Regulation of Viral Gene Expression
    Identification of a Conserved RNA Replication Element (cre) within the 3Dpol-Coding Sequence of Hepatoviruses
    Yan Yang, MinKyung Yi, David J. Evans, Peter Simmonds, Stanley M. Lemon
  • Genome Replication and Regulation of Viral Gene Expression
    A Viral Noncoding RNA Generated by cis-Element-Mediated Protection against 5′→3′ RNA Decay Represses both Cap-Independent and Cap-Dependent Translation
    Hiro-oki Iwakawa, Hiroyuki Mizumoto, Hideaki Nagano, Yuka Imoto, Kazuma Takigawa, Siriruk Sarawaneeyaruk, Masanori Kaido, Kazuyuki Mise, Tetsuro Okuno
  • Genome Replication and Regulation of Viral Gene Expression
    Mutational Evidence for a Structural Model of the Lassa Virus RNA Polymerase Domain and Identification of Two Residues, Gly1394 and Asp1395, That Are Critical for Transcription but Not Replication of the Genome
    Meike Hass, Michaela Lelke, Carola Busch, Beate Becker-Ziaja, Stephan Günther
  • Genome Replication and Regulation of Viral Gene Expression
    Monomeric Linear RNA of Citrus Exocortis Viroid Resulting from Processing In Vivo Has 5′-Phosphomonoester and 3′-Hydroxyl Termini: Implications for the RNase and RNA Ligase Involved in Replication
    María-Eugenia Gas, Diego Molina-Serrano, Carmen Hernández, Ricardo Flores, José-Antonio Daròs

Virus-Cell Interactions

  • Virus-Cell Interactions
    Small-Ruminant Lentivirus Enhances PrPSc Accumulation in Cultured Sheep Microglial Cells
    James B. Stanton, Donald P. Knowles, Katherine I. O'Rourke, Lynn M. Herrmann-Hoesing, Bruce A. Mathison, Timothy V. Baszler
  • Virus-Cell Interactions | Spotlight
    Scrapie-Induced Defects in Learning and Memory of Transgenic Mice Expressing Anchorless Prion Protein Are Associated with Alterations in the Gamma Aminobutyric Acid-Ergic Pathway
    Matthew J. Trifilo, Manuel Sanchez-Alavez, Laura Solforosi, Joie Bernard-Trifilo, Stefan Kunz, Dorian McGavern, Michael B. A. Oldstone
  • Virus-Cell Interactions
    Ectromelia Virus Encodes a Novel Family of F-Box Proteins That Interact with the SCF Complex
    Nick van Buuren, Brianne Couturier, Yue Xiong, Michele Barry
  • Virus-Cell Interactions
    Human Immunodeficiency Virus Type 1 Replication and Regulation of APOBEC3G by Peptidyl Prolyl Isomerase Pin1
    Koichi Watashi, Mohammad Khan, Venkat R. K. Yedavalli, Man Lung Yeung, Klaus Strebel, Kuan-Teh Jeang
  • Virus-Cell Interactions
    Bap31 Is a Novel Target of the Human Papillomavirus E5 Protein
    Jennifer A. Regan, Laimonis A. Laimins
  • Virus-Cell Interactions
    Vaccinia Virus WR53.5/F14.5 Protein Is a New Component of Intracellular Mature Virus and Is Important for Calcium-Independent Cell Adhesion and Vaccinia Virus Virulence in Mice
    Roza Izmailyan, Wen Chang
  • Virus-Cell Interactions
    Efficient Quiescent Infection of Normal Human Diploid Fibroblasts with Wild-Type Herpes Simplex Virus Type 1
    Robert McMahon, Derek Walsh
  • Virus-Cell Interactions
    The Vaccinia Virus Gene I2L Encodes a Membrane Protein with an Essential Role in Virion Entry
    R. Jeremy Nichols, Eleni Stanitsa, Bethany Unger, Paula Traktman

Structure and Assembly

  • Structure and Assembly | Spotlight
    Possible Role for Cellular Karyopherins in Regulating Polyomavirus and Papillomavirus Capsid Assembly
    Gregory Bird, Malinda O'Donnell, Junona Moroianu, Robert L. Garcea
  • Structure and Assembly
    Subviral Particle Release Determinants of Prototype Foamy Virus
    Annett Stange, Daniel Lüftenegger, Juliane Reh, Winfried Weissenhorn, Dirk Lindemann
  • Structure and Assembly
    Kinesin KIF4 Regulates Intracellular Trafficking and Stability of the Human Immunodeficiency Virus Type 1 Gag Polyprotein
    Nathaniel W. Martinez, Xiaoxiao Xue, Reem G. Berro, Geri Kreitzer, Marilyn D. Resh
  • Structure and Assembly | Spotlight
    The Influenza Virus M2 Protein Cytoplasmic Tail Interacts with the M1 Protein and Influences Virus Assembly at the Site of Virus Budding
    Benjamin J. Chen, George P. Leser, David Jackson, Robert A. Lamb
  • Structure and Assembly
    Amino Acid Preferences of Retroviral Proteases for Amino-Terminal Positions in a Type 1 Cleavage Site
    Helga Eizert, Pálma Bander, Péter Bagossi, Tamás Sperka, Gabriella Miklóssy, Péter Boross, Irene T. Weber, József Tözsér
  • Structure and Assembly
    Retroviral Nucleocapsid Proteins Display Nonequivalent Levels of Nucleic Acid Chaperone Activity
    Kristen M. Stewart-Maynard, Margareta Cruceanu, Fei Wang, My-Nuong Vo, Robert J. Gorelick, Mark C. Williams, Ioulia Rouzina, Karin Musier-Forsyth
  • Structure and Assembly
    Small-Molecule Effectors of Hepatitis B Virus Capsid Assembly Give Insight into Virus Life Cycle
    Christina Bourne, Sejin Lee, Bollu Venkataiah, Angela Lee, Brent Korba, M. G. Finn, Adam Zlotnick
  • Structure and Assembly
    Adenovirus IVa2 Protein Binds ATP
    Philomena Ostapchuk, Patrick Hearing

Vaccines and Antiviral Agents

  • Vaccines and Antiviral Agents
    Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36Mut(e,g) Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41
    Elena Gustchina, Carole A Bewley, G. Marius Clore
  • Vaccines and Antiviral Agents
    Gag-Specific Cytotoxic T-Lymphocyte-Based Control of Primary Simian Immunodeficiency Virus Replication in a Vaccine Trial
    Miki Kawada, Tetsuo Tsukamoto, Hiroyuki Yamamoto, Nami Iwamoto, Kyoko Kurihara, Akiko Takeda, Chikaya Moriya, Hiroaki Takeuchi, Hirofumi Akari, Tetsuro Matano

Cellular Response to Infection

  • Cellular Response to Infection
    Sendai Virus C Protein Plays a Role in Restricting PKR Activation by Limiting the Generation of Intracellular Double-Stranded RNA
    Kenji Takeuchi, Takayuki Komatsu, Yoshinori Kitagawa, Kiyonao Sada, Bin Gotoh
  • Cellular Response to Infection
    Cell Cycle-Independent Expression of Immediate-Early Gene 3 Results in G1 and G2 Arrest in Murine Cytomegalovirus-Infected Cells
    Lüder Wiebusch, Anke Neuwirth, Linus Grabenhenrich, Sebastian Voigt, Christian Hagemeier

Gene Delivery

  • Gene Delivery
    Construction of a Fully Retargeted Herpes Simplex Virus 1 Recombinant Capable of Entering Cells Solely via Human Epidermal Growth Factor Receptor 2
    Laura Menotti, Arianna Cerretani, Hartmut Hengel, Gabriella Campadelli-Fiume

Transformation and Oncogenesis

  • Transformation and Oncogenesis
    Latent Membrane Protein 1 of Epstein-Barr Virus Activates the hTERT Promoter and Enhances Telomerase Activity in B Lymphocytes
    Liliana Terrin, Jessica Dal Col, Enrica Rampazzo, Paola Zancai, Moreno Pedrotti, Grazia Ammirabile, Stefano Bergamin, Silvana Rizzo, Riccardo Dolcetti, Anita De Rossi

Genetic Diversity and Evolution

  • Genetic Diversity and Evolution
    Gain, Preservation, and Loss of a Group 1a Coronavirus Accessory Glycoprotein
    Alessio Lorusso, Nicola Decaro, Pepijn Schellen, Peter J. M. Rottier, Canio Buonavoglia, Bert-Jan Haijema, Raoul J. de Groot

Letters to the Editor

  • Letter to the Editor
    Transitory Viremic Surges in a Human Immunodeficiency Virus-Positive Elite Controller Can Shift the Cellular Transcriptome Profile: a Word of Caution for Microarray Studies
    Jing Qin Wu, Bin Wang, Nitin K. Saksena
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Journal of Virology: 82 (20)

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volume 82, issue 20
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