Journal of Virology: 82 (19)

October 1, 2008; Volume 82,Issue 19

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Articles of Significant Interest Selected from This Issue by the Editors

Genome Replication and Regulation of Viral Gene Expression

Genome Replication and Regulation of Viral Gene Expression
Leader of the Capsid Protein in Feline Calicivirus Promotes Replication of Norwalk Virus in Cell Culture
Kyeong-Ok Chang, David W. George, John B. Patton, Kim Y. Green, Stanislav V. Sosnovtsev
Genome Replication and Regulation of Viral Gene Expression
ERK1/2-Mediated Phosphorylation of Small Hepatitis Delta Antigen at Serine 177 Enhances Hepatitis Delta Virus Antigenomic RNA Replication
Yen-Shun Chen, Wen-Hung Huang, Shiao-Ya Hong, Yeou-Guang Tsay, Pei-Jer Chen
Genome Replication and Regulation of Viral Gene Expression
Transcriptional Control of Spliced and Unspliced Human T-Cell Leukemia Virus Type 1 bZIP Factor (HBZ) Gene
Mika Yoshida, Yorifumi Satou, Jun-ichirou Yasunaga, Jun-ichi Fujisawa, Masao Matsuoka
Genome Replication and Regulation of Viral Gene Expression
Poliovirus cis-Acting Replication Element-Dependent VPg Uridylylation Lowers the K_m of the Initiating Nucleoside Triphosphate for Viral RNA Replication
Benjamin P. Steil, David J. Barton
Genome Replication and Regulation of Viral Gene Expression
Transcription of Subgenomic mRNA of Hepatitis Delta Virus Requires a Modified Hepatitis Delta Antigen That Is Distinct from Antigenomic RNA Synthesis
Chung-Hsin Tseng, King-Song Jeng, Michael M. C. Lai
Genome Replication and Regulation of Viral Gene Expression
Targeting Tat Inhibitors in the Assembly of Human Immunodeficiency Virus Type 1 Transcription Complexes
Iván D'Orso, Jocelyn R. Grunwell, Robert L. Nakamura, Chandreyee Das, Alan D. Frankel
Genome Replication and Regulation of Viral Gene Expression | Spotlight
Dynamic Histone H3 Acetylation and Methylation at Human Cytomegalovirus Promoters during Replication in Fibroblasts
Christian Cuevas-Bennett, Thomas Shenk
Genome Replication and Regulation of Viral Gene Expression
Polymerase Read-Through at the First Transcription Termination Site Contributes to Regulation of Borna Disease Virus Gene Expression
Marion Poenisch, Sandra Wille, Peter Staeheli, Urs Schneider
Genome Replication and Regulation of Viral Gene Expression | Spotlight
The DNA Damage Sensors Ataxia-Telangiectasia Mutated Kinase and Checkpoint Kinase 2 Are Required for Hepatitis C Virus RNA Replication
Yasuo Ariumi, Misao Kuroki, Hiromichi Dansako, Ken-Ichi Abe, Masanori Ikeda, Takaji Wakita, Nobuyuki Kato
Genome Replication and Regulation of Viral Gene Expression
Aichi Virus 2A Protein Is Involved in Viral RNA Replication
Jun Sasaki, Koki Taniguchi

Structure and Assembly

Structure and Assembly
Mutations in Human Immunodeficiency Virus Type 1 Nucleocapsid Protein Zinc Fingers Cause Premature Reverse Transcription
James A. Thomas, William J. Bosche, Teresa L. Shatzer, Donald G. Johnson, Robert J. Gorelick
Structure and Assembly
Control of Cytoplasmic Maturation Events by Cytomegalovirus Tegument Protein pp150
Ritesh Tandon, Edward S. Mocarski
Structure and Assembly
Crystal Structure of Coxsackievirus B3 3D^pol Highlights the Functional Importance of Residue 5 in Picornavirus Polymerases
Grace Campagnola, Mark Weygandt, Kirsten Scoggin, Olve Peersen
Structure and Assembly | Spotlight
Structure of Flexible Filamentous Plant Viruses
Amy Kendall, Michele McDonald, Wen Bian, Timothy Bowles, Sarah C. Baumgarten, Jian Shi, Phoebe L. Stewart, Esther Bullitt, David Gore, Thomas C. Irving, Wendy M. Havens, Said A. Ghabrial, Joseph S. Wall, Gerald Stubbs
Structure and Assembly
The Crystal Structure of Coxsackievirus B3 RNA-Dependent RNA Polymerase in Complex with Its Protein Primer VPg Confirms the Existence of a Second VPg Binding Site on Picornaviridae Polymerases
Arnaud Gruez, Barbara Selisko, Michael Roberts, Gérard Bricogne, Cécile Bussetta, Ilham Jabafi, Bruno Coutard, Armando M. De Palma, Johan Neyts, Bruno Canard
Structure and Assembly
Apolipoprotein C1 Association with Hepatitis C Virus
Jean-Christophe Meunier, Rodney S. Russell, Ronald E. Engle, Kristina N. Faulk, Robert H. Purcell, Suzanne U. Emerson
Structure and Assembly
Basal Budding and Replication of the Murine Leukemia Virus Are Independent of the Gag L Domains
Yosef Sabo, Nihay Laham-Karam, Eran Bacharach
Structure and Assembly
Inhibition of Human Immunodeficiency Virus Type 1 Assembly and Release by the Cholesterol-Binding Compound Amphotericin B Methyl Ester: Evidence for Vpu Dependence
Abdul A. Waheed, Sherimay D. Ablan, Ferri Soheilian, Kunio Nagashima, Akira Ono, Carl P. Schaffner, Eric O. Freed
Structure and Assembly
The F-Like Protein Ac23 Enhances the Infectivity of the Budded Virus of gp64-Null Autographa californica Multinucleocapsid Nucleopolyhedrovirus Pseudotyped with Baculovirus Envelope Fusion Protein F
Manli Wang, Ying Tan, Feifei Yin, Fei Deng, Just M. Vlak, Zhihong Hu, Hualin Wang

Genetic Diversity and Evolution

Genetic Diversity and Evolution
Human Endogenous Retrovirus K (HML-2) Elements in the Plasma of People with Lymphoma and Breast Cancer
Rafael Contreras-Galindo, Mark H. Kaplan, Philippe Leissner, Thibault Verjat, Ilaria Ferlenghi, Fabio Bagnoli, Fabiola Giusti, Michael H. Dosik, Daniel F. Hayes, Scott D. Gitlin, David M. Markovitz
Genetic Diversity and Evolution
Comparative Analysis of Nearly Full-Length Hepatitis C Virus Quasispecies from Patients Experiencing Viral Breakthrough during Antiviral Therapy: Clustered Mutations in Three Functional Genes, E2, NS2, and NS5a
Zekuan Xu, Xiaofeng Fan, Yanjuan Xu, Adrian M. Di Bisceglie

Pathogenesis and Immunity

Pathogenesis and Immunity
Herpes Simplex Virus Downregulates Secretory Leukocyte Protease Inhibitor: a Novel Immune Evasion Mechanism
Esra Fakioglu, Sarah S. Wilson, Pedro M. M. Mesquita, Ehsan Hazrati, Natalia Cheshenko, John A. Blaho, Betsy C. Herold
Pathogenesis and Immunity
Genomic Analysis Reveals Age-Dependent Innate Immune Responses to Severe Acute Respiratory Syndrome Coronavirus
Tracey Baas, Anjeanette Roberts, Thomas H. Teal, Leatrice Vogel, Jun Chen, Terrence M. Tumpey, Michael G. Katze, Kanta Subbarao
Pathogenesis and Immunity
γδT Cells Initiate Acute Inflammation and Injury in Adenovirus-Infected Liver via Cytokine-Chemokine Cross Talk
Maureen N. Ajuebor, Yijun Jin, Griffin L. Gremillion, Robert M. Strieter, Qingling Chen, Patrick A. Adegboyega
Pathogenesis and Immunity
Ligand-Independent Exhaustion of Killer Immunoglobulin-Like Receptor-Positive CD8⁺ T Cells in Human Immunodeficiency Virus Type 1 Infection
Galit Alter, Suzannah Rihn, Hendrik Streeck, Nickolas Teigen, Alicja Piechocka-Trocha, Kristin Moss, Kristen Cohen, Angela Meier, Florencia Pereyra, Bruce Walker, Marcus Altfeld
Pathogenesis and Immunity
Effector CD4⁺ T-Cell Involvement in Clearance of Infectious Herpes Simplex Virus Type 1 from Sensory Ganglia and Spinal Cords
Alison J. Johnson, Chin-Fun Chu, Gregg N. Milligan
Pathogenesis and Immunity
Cytopathogenicity of Classical Swine Fever Virus Correlates with Attenuation in the Natural Host
Andreas Gallei, Sandra Blome, Stefanie Gilgenbach, Norbert Tautz, Volker Moennig, Paul Becher
Pathogenesis and Immunity
Potent Antibody-Mediated Neutralization and Evolution of Antigenic Escape Variants of Simian Immunodeficiency Virus Strain SIVmac239 In Vivo
Shuji Sato, Eloisa Yuste, William A. Lauer, Eun Hyuk Chang, Jennifer S. Morgan, Jacqueline G. Bixby, Jeffrey D. Lifson, Ronald C. Desrosiers, Welkin E. Johnson
Pathogenesis and Immunity
Llama-Derived Single-Chain Antibody Fragments Directed to Rotavirus VP6 Protein Possess Broad Neutralizing Activity In Vitro and Confer Protection against Diarrhea in Mice
Lorena Garaicoechea, Aurelien Olichon, Gisela Marcoppido, Andrés Wigdorovitz, Marina Mozgovoj, Linda Saif, Thomas Surrey, Viviana Parreño
Pathogenesis and Immunity
The Kinetics of Hepatitis C Virus-Specific CD8 T-Cell Responses in the Blood Mirror Those in the Liver in Acute Hepatitis C Virus Infection
Eui-Cheol Shin, Stefania Capone, Riccardo Cortese, Stefano Colloca, Alfredo Nicosia, Antonella Folgori, Barbara Rehermann
Pathogenesis and Immunity
Gag-Specific CD4⁺ T-Cell Frequency Is Inversely Correlated with Proviral Load and Directly Correlated with Immune Activation in Infection with Human Immunodeficiency Virus Type 2 (HIV-2) but Not HIV-1
Russell B. Foxall, Catarina S. Cortesão, Adriana S. Albuquerque, Rui S. Soares, Rui M. M. Victorino, Ana E. Sousa

Virus-Cell Interactions

Virus-Cell Interactions
A Hyperfusogenic F Protein Enhances the Oncolytic Potency of a Paramyxovirus Simian Virus 5 P/V Mutant without Compromising Sensitivity to Type I Interferon
Maria D. Gainey, Mary J. Manuse, Griffith D. Parks
Virus-Cell Interactions
Cleavage of Poly(A)-Binding Protein by Poliovirus 3C Proteinase Inhibits Viral Internal Ribosome Entry Site-Mediated Translation
Jennifer M. Bonderoff, Jennifer L. LaRey, Richard E. Lloyd
Virus-Cell Interactions
An Equine Infectious Anemia Virus Variant Superinfects Cells through Novel Receptor Interactions
Melinda A. Brindley, Baoshan Zhang, Ronald C. Montelaro, Wendy Maury
Virus-Cell Interactions
Human Immunodeficiency Virus Type 1 Envelope gp120 Induces a Stop Signal and Virological Synapse Formation in Noninfected CD4⁺ T Cells
Gaia Vasiliver-Shamis, Michael Tuen, Teresa W. Wu, Toby Starr, Thomas O. Cameron, Russell Thomson, Gurvinder Kaur, Jianping Liu, Maria Luisa Visciano, Hualin Li, Rajnish Kumar, Rais Ansari, Dong P. Han, Michael W. Cho, Michael L. Dustin, Catarina E. Hioe
Virus-Cell Interactions
The Transmembrane Domain of the Severe Acute Respiratory Syndrome Coronavirus ORF7b Protein Is Necessary and Sufficient for Its Retention in the Golgi Complex
Scott R. Schaecher, Michael S. Diamond, Andrew Pekosz
Virus-Cell Interactions
Caveolin-1-Dependent Infectious Entry of Human Papillomavirus Type 31 in Human Keratinocytes Proceeds to the Endosomal Pathway for pH-Dependent Uncoating
Jessica L. Smith, Samuel K. Campos, Angela Wandinger-Ness, Michelle A. Ozbun
Virus-Cell Interactions
Association of the Cellular Coactivator HCF-1 with the Golgi Apparatus in Sensory Neurons
Gaelle Kolb, Thomas M. Kristie
Virus-Cell Interactions
Two Regions within the Amino-Terminal Half of APOBEC3G Cooperate To Determine Cytoplasmic Localization
Mark D. Stenglein, Hiroshi Matsuo, Reuben S. Harris
Virus-Cell Interactions
Remodeling of Endothelial Adherens Junctions by Kaposi's Sarcoma-Associated Herpesvirus
Mandana Mansouri, Patrick P. Rose, Ashlee V. Moses, Klaus Früh
Virus-Cell Interactions
Functional Characterization of the Human Immunodeficiency Virus Type 1 Nef Acidic Domain
Laura L. Baugh, J. Victor Garcia, John L. Foster
Virus-Cell Interactions
A Mobile Functional Region of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein Independently Regulates DNA Binding and Protein Abundance
Pey-Jium Chang, Duane Shedd, George Miller
Virus-Cell Interactions
PPEY Motif within the Rabies Virus (RV) Matrix Protein Is Essential for Efficient Virion Release and RV Pathogenicity
Christoph Wirblich, Gene S. Tan, Amy Papaneri, Peter J. Godlewski, Jan Marc Orenstein, Ronald N. Harty, Matthias J. Schnell
Virus-Cell Interactions
Spontaneous Heteromerization of Gammaretrovirus Envelope Proteins: a Possible Novel Mechanism of Retrovirus Restriction
Marie Dewannieux, Mary K. Collins

Cellular Response to Infection

Cellular Response to Infection
Adenovirus E4orf4 Protein Downregulates MYC Expression through Interaction with the PP2A-B55 Subunit
Haggit Ben-Israel, Rakefet Sharf, Gideon Rechavi, Tamar Kleinberger
Cellular Response to Infection
Quantitative Whole-Cell Proteome Analysis of Pseudorabies Virus-Infected Cells
Martin Skiba, Thomas C. Mettenleiter, Axel Karger

Gene Delivery

Gene Delivery | Spotlight
Frequency and Spectrum of Genomic Integration of Recombinant Adeno-Associated Virus Serotype 8 Vector in Neonatal Mouse Liver
Katsuya Inagaki, Chuncheng Piao, Nicole M. Kotchey, Xiaolin Wu, Hiroyuki Nakai

Transformation and Oncogenesis

Transformation and Oncogenesis
The Interaction between Human Papillomavirus Type 16 and FADD Is Mediated by a Novel E6 Binding Domain
Sandy S. Tungteakkhun, Maria Filippova, Jonathan W. Neidigh, Nadja Fodor, Penelope J. Duerksen-Hughes

Vaccines and Antiviral Agents

Vaccines and Antiviral Agents
Reduced Protection from Simian Immunodeficiency Virus SIV_mac251 Infection Afforded by Memory CD8⁺ T Cells Induced by Vaccination during CD4⁺ T-Cell Deficiency
Monica Vaccari, Joseph Mattapallil, Kaimei Song, Wen-Po Tsai, Anna Hryniewicz, David Venzon, Maurizio Zanetti, Keith A. Reimann, Mario Roederer, Genoveffa Franchini

Letters to the Editor

Letter to the Editor
What Are the Risks—Hypothetical and Observed—of Recombination Involving Live Vaccines and Vaccine Vectors Based on Nonsegmented Negative-Strain RNA Viruses?
Peter L. Collins, Alexander Bukreyev, Brian R. Murphy

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Table of Contents

Spotlight

Genome Replication and Regulation of Viral Gene Expression

Structure and Assembly

Genetic Diversity and Evolution

Pathogenesis and Immunity

Virus-Cell Interactions

Cellular Response to Infection

Gene Delivery

Transformation and Oncogenesis

Vaccines and Antiviral Agents

Letters to the Editor

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