Journal of Virology: 82 (16)

August 15, 2008; Volume 82,Issue 16

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Articles of Significant Interest Selected from This Issue by the Editors

Virus-Cell Interactions

Virus-Cell Interactions
Competition Model for Upregulation of the Major Histocompatibility Complex Class II-Associated Invariant Chain by Human Immunodeficiency Virus Type 1 Nef
Richard S. Mitchell, Rittik Chaudhuri, O. Wolf Lindwasser, Kristie A. Tanaka, David Lau, Rudy Murillo, Juan S. Bonifacino, John C. Guatelli
Virus-Cell Interactions
Properties of Subviral Particles of Hepatitis B Virus
Ning Chai, Ho Eun Chang, Emmanuelle Nicolas, Ziying Han, Michal Jarnik, John Taylor
Virus-Cell Interactions
Structural Variations in Species B Adenovirus Fibers Impact CD46 Association
Lars Pache, Sangita Venkataraman, Vijay S. Reddy, Glen R. Nemerow
Virus-Cell Interactions | Spotlight
A Novel Cellular Protein, VPEF, Facilitates Vaccinia Virus Penetration into HeLa Cells through Fluid Phase Endocytosis
Cheng-Yen Huang, Tsai-Yi Lu, Chi-Horng Bair, Yuan-Shau Chang, Jeng-Kuan Jwo, Wen Chang
Virus-Cell Interactions
Structural Insights into Calicivirus Attachment and Uncoating
David Bhella, Derek Gatherer, Yasmin Chaudhry, Rebecca Pink, Ian G. Goodfellow
Virus-Cell Interactions
Effects of Lamin A/C, Lamin B1, and Viral U_S3 Kinase Activity on Viral Infectivity, Virion Egress, and the Targeting of Herpes Simplex Virus U_L34-Encoded Protein to the Inner Nuclear Membrane
Fan Mou, Elizabeth G. Wills, Richard Park, Joel D. Baines
Virus-Cell Interactions
Mouse Hepatitis Virus Type 2 Enters Cells through a Clathrin-Mediated Endocytic Pathway Independent of Eps15
Yinghui Pu, Xuming Zhang
Virus-Cell Interactions
Epstein-Barr Virus Latent Membrane Protein 1 Represses DNA Repair through the PI3K/Akt/FOXO3a Pathway in Human Epithelial Cells
Yi-Ren Chen, Ming-Tsan Liu, Yu-Ting Chang, Chung-Chun Wu, Chi-Yuan Hu, Jen-Yang Chen
Virus-Cell Interactions | Spotlight
Structural Analysis Reveals an Amyloid Form of the Human Papillomavirus Type 16 E1^∧E4 Protein and Provides a Molecular Basis for Its Accumulation
Pauline B. McIntosh, Stephen R. Martin, Deborah J. Jackson, Jameela Khan, Erin R. Isaacson, Lesley Calder, Kenneth Raj, Heather M. Griffin, Qian Wang, Peter Laskey, John F. Eccleston, John Doorbar
Virus-Cell Interactions
Amino Acid 226 in the Hemagglutinin of H4N6 Influenza Virus Determines Binding Affinity for α2,6-Linked Sialic Acid and Infectivity Levels in Primary Swine and Human Respiratory Epithelial Cells
Allen C. Bateman, Marc G. Busch, Alexander I. Karasin, Nicolai Bovin, Christopher W. Olsen
Virus-Cell Interactions
Deoxynucleoside Triphosphate Incorporation Mechanism of Foamy Virus (FV) Reverse Transcriptase: Implications for Cell Tropism of FV
Jose Santos-Velazquez, Baek Kim

Pathogenesis and Immunity

Pathogenesis and Immunity
A Simple Mathematical Model Helps To Explain the Immunodominance of CD8 T Cells in Influenza A Virus Infections
Andreas Handel, Rustom Antia
Pathogenesis and Immunity
Virological Consequences of Early Events following Cell-Cell Contact between Human Immunodeficiency Virus Type 1-Infected and Uninfected CD4⁺ Cells
Eliana Ruggiero, Roberta Bona, Claudia Muratori, Maurizio Federico
Pathogenesis and Immunity
Human Immunodeficiency Virus Infection Alters Tumor Necrosis Factor Alpha Production via Toll-Like Receptor-Dependent Pathways in Alveolar Macrophages and U1 Cells
Marlynne Q. Nicol, Jean-Marie Mathys, Albertina Pereira, Kevin Ollington, Michael H. Ieong, Paul R. Skolnik
Pathogenesis and Immunity
Regulation of Cytokine Production by Virus-Specific CD8 T Cells in the Lungs
Ross B. Fulton, Matthew R. Olson, Steven M. Varga
Pathogenesis and Immunity
The Large Polymerase Protein Is Associated with the Virulence of Newcastle Disease Virus
Subrat N. Rout, Siba K. Samal
Pathogenesis and Immunity
Impaired Naive and Memory B-Cell Responsiveness to TLR9 Stimulation in Human Immunodeficiency Virus Infection
Wei Jiang, Michael M. Lederman, Richard J. Mohner, Benigno Rodriguez, Todd M. Nedrich, Clifford V. Harding, Scott F. Sieg
Pathogenesis and Immunity | Spotlight
A Single N-Linked Glycosylation Site in the Japanese Encephalitis Virus prM Protein Is Critical for Cell Type-Specific prM Protein Biogenesis, Virus Particle Release, and Pathogenicity in Mice
Jeong-Min Kim, Sang-Im Yun, Byung-Hak Song, Youn-Soo Hahn, Chan-Hee Lee, Hyun-Woo Oh, Young-Min Lee
Pathogenesis and Immunity
Dendritic Cells Preferentially Transfer CXCR4-Using Human Immunodeficiency Virus Type 1 Variants to CD4⁺ T Lymphocytes in trans
Thijs van Montfort, Adri A. M. Thomas, Georgios Pollakis, William A. Paxton
Pathogenesis and Immunity
Autologous Neutralizing Humoral Immunity and Evolution of the Viral Envelope in the Course of Subtype B Human Immunodeficiency Virus Type 1 Infection
Evelien M. Bunnik, Linaida Pisas, Ad C. van Nuenen, Hanneke Schuitemaker
Pathogenesis and Immunity
Replication Properties of Clade A/C Chimeric Feline Immunodeficiency Viruses and Evaluation of Infection Kinetics in the Domestic Cat
Sohela de Rozìeres, Jesse Thompson, Magnus Sundstrom, Julia Gruber, Debora S. Stump, Aymeric P. de Parseval, Sue VandeWoude, John H. Elder
Pathogenesis and Immunity
Influenza Virus Infection Augments NK Cell Inhibition through Reorganization of Major Histocompatibility Complex Class I Proteins
Hagit Achdout, Irit Manaster, Ofer Mandelboim
Pathogenesis and Immunity
In Vivo Potential Effects of Adenovirus Type 5 E1A and E1B on Lung Carcinogenesis and Lymphoproliferative Inflammation
Yongping Yang, Colin McKerlie, Zhan Lu, Lena Wang, Manuel Buchwald
Pathogenesis and Immunity
Effective Chemokine Secretion by Dendritic Cells and Expansion of Cross-Presenting CD4⁻/CD8⁺ Dendritic Cells Define a Protective Phenotype in the Mouse Model of Coxsackievirus Myocarditis
Andreas Oliver Weinzierl, Gudrun Szalay, Hartwig Wolburg, Martina Sauter, Hans-Georg Rammensee, Reinhard Kandolf, Stefan Stevanović, Karin Klingel
Pathogenesis and Immunity
Previously Infected Chimpanzees Are Not Consistently Protected against Reinfection or Persistent Infection after Reexposure to the Identical Hepatitis C Virus Strain
Jens Bukh, Robert Thimme, Jean-Christophe Meunier, Kristina Faulk, Hans Christian Spangenberg, Kyong-Mi Chang, William Satterfield, Francis V. Chisari, Robert H. Purcell
Pathogenesis and Immunity
The High Prevalence of Herpes Simplex Virus Type 1 DNA in Human Trigeminal Ganglia Is Not a Function of Age or Gender
James M. Hill, Melvyn J. Ball, Donna M. Neumann, Ann M. Azcuy, Partha S. Bhattacharjee, Saadallah Bouhanik, Christian Clement, Walter J. Lukiw, Timothy P. Foster, Manish Kumar, Herbert E. Kaufman, Hilary W. Thompson

Gene Delivery

Gene Delivery
The Core Element of a CpG Island Protects Avian Sarcoma and Leukosis Virus-Derived Vectors from Transcriptional Silencing
Filip Šenigl, Jiří Plachý, Jiří Hejnar
Gene Delivery
Adeno-Associated Virus Vector Genomes Persist as Episomal Chromatin in Primate Muscle
Magalie Penaud-Budloo, Caroline Le Guiner, Ali Nowrouzi, Alice Toromanoff, Yan Chérel, Pierre Chenuaud, Manfred Schmidt, Christof von Kalle, Fabienne Rolling, Philippe Moullier, Richard O. Snyder

Genetic Diversity and Evolution

Genetic Diversity and Evolution
Phylogenetic and Genetic Analysis of Feline Immunodeficiency Virus gag, pol, and env Genes from Domestic Cats Undergoing Nucleoside Reverse Transcriptase Inhibitor Treatment or Treatment-Naïve Cats in Rio de Janeiro, Brazil
Angelica N. Martins, Sheila O. Medeiros, Jose P. Simonetti, Hermann G. Schatzmayr, Amílcar Tanuri, Rodrigo M. Brindeiro
Genetic Diversity and Evolution
Human Immunodeficiency Virus (HIV) Type 1 Proviral Hypermutation Correlates with CD4 Count in HIV-Infected Women from Kenya
Allison M. Land, T. Blake Ball, Ma Luo, Richard Pilon, Paul Sandstrom, Joanne E. Embree, Charles Wachihi, Joshua Kimani, Francis A. Plummer

Genome Replication and Regulation of Viral Gene Expression

Genome Replication and Regulation of Viral Gene Expression
Sf29 Gene of Spodoptera frugiperda Multiple Nucleopolyhedrovirus Is a Viral Factor That Determines the Number of Virions in Occlusion Bodies
Oihane Simón, Trevor Williams, Aaron C. Asensio, Sarhay Ros, Andrea Gaya, Primitivo Caballero, Robert D. Possee
Genome Replication and Regulation of Viral Gene Expression
Interaction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus Particles
Takahiro Masaki, Ryosuke Suzuki, Kyoko Murakami, Hideki Aizaki, Koji Ishii, Asako Murayama, Tomoko Date, Yoshiharu Matsuura, Tatsuo Miyamura, Takaji Wakita, Tetsuro Suzuki
Genome Replication and Regulation of Viral Gene Expression
The Secondary Structure of the Human Immunodeficiency Virus Type 1 Transcript Modulates Viral Splicing and Infectivity
Joseph A. Jablonski, Emanuele Buratti, Cristiana Stuani, Massimo Caputi
Genome Replication and Regulation of Viral Gene Expression | Spotlight
Coronavirus Nonstructural Protein 16 Is a Cap-0 Binding Enzyme Possessing (Nucleoside-2′O)-Methyltransferase Activity
Etienne Decroly, Isabelle Imbert, Bruno Coutard, Mickaël Bouvet, Barbara Selisko, Karine Alvarez, Alexander E. Gorbalenya, Eric J. Snijder, Bruno Canard
Genome Replication and Regulation of Viral Gene Expression
Functional Characterization of the Cleavage Specificity of the Sapovirus Chymotrypsin-Like Protease
Ivonne Robel, Julia Gebhardt, Jeroen R. Mesters, Alexander Gorbalenya, Bruno Coutard, Bruno Canard, Rolf Hilgenfeld, Jacques Rohayem
Genome Replication and Regulation of Viral Gene Expression
Liver-Specific MicroRNA miR-122 Enhances the Replication of Hepatitis C Virus in Nonhepatic Cells
Jinhong Chang, Ju-Tao Guo, Dong Jiang, Haitao Guo, John M. Taylor, Timothy M. Block

Structure and Assembly

Structure and Assembly
The Envelope of Intracellular African Swine Fever Virus Is Composed of a Single Lipid Bilayer
Philippa C. Hawes, Christopher L. Netherton, Thomas E. Wileman, Paul Monaghan
Structure and Assembly
Mutagenesis and Nuclear Magnetic Resonance Analyses of the Fusion Peptide of Helicoverpa armigera Single Nucleocapsid Nucleopolyhedrovirus F Protein
Ying Tan, Ling Jiang, Manli Wang, Feifei Yin, Fei Deng, Maili Liu, Zhihong Hu, Hualin Wang

Transformation and Oncogenesis

Transformation and Oncogenesis
Cross Talk between Expression of the Human T-Cell Leukemia Virus Type 1 Tax Transactivator and the Oncogenic bHLH Transcription Factor TAL1
Jean-Michel Terme, Melanie Wencker, Arnaud Favre-Bonvin, Françoise Bex, Louis Gazzolo, Madeleine Duc Dodon, Pierre Jalinot

Cellular Response to Infection

Cellular Response to Infection
Human Parvovirus B19 NS1 Protein Modulates Inflammatory Signaling by Activation of STAT3/PIAS3 in Human Endothelial Cells
Anja Duechting, Carsten Tschöpe, Heike Kaiser, Tobias Lamkemeyer, Nobuyuki Tanaka, Susanne Aberle, Florian Lang, Joseph Torresi, Reinhard Kandolf, C.-Thomas Bock
Cellular Response to Infection
Cellular La Protein Shields Nonsegmented Negative-Strand RNA Viral Leader RNA from RIG-I and Enhances Virus Growth by Diverse Mechanisms
Vira Bitko, Alla Musiyenko, Mark A. Bayfield, Richard J. Maraia, Sailen Barik
Cellular Response to Infection
Murine Gammaherpesvirus 68 Open Reading Frame 75c Tegument Protein Induces the Degradation of PML and Is Essential for Production of Infectious Virus
Paul D. Ling, Jie Tan, Jaturong Sewatanon, RongSheng Peng
Cellular Response to Infection
Role of Interferon in the Replication of Human Parainfluenza Virus Type 1 Wild Type and Mutant Viruses in Human Ciliated Airway Epithelium
Emmalene J. Bartlett, Margaret Hennessey, Mario H. Skiadopoulos, Alexander C. Schmidt, Peter L. Collins, Brian R. Murphy, Raymond J. Pickles
Cellular Response to Infection
Human Metapneumovirus Small Hydrophobic Protein Inhibits NF-κB Transcriptional Activity
Xiaoyong Bao, Deepthi Kolli, Tianshuang Liu, Yichu Shan, Roberto P. Garofalo, Antonella Casola

Vaccines and Antiviral Agents

Vaccines and Antiviral Agents
Zinc Finger Proteins Designed To Specifically Target Duck Hepatitis B Virus Covalently Closed Circular DNA Inhibit Viral Transcription in Tissue Culture
Kimberley A. Zimmerman, Karl P. Fischer, Michael A. Joyce, D. Lorne J. Tyrrell
Vaccines and Antiviral Agents
Disparity between Levels of In Vitro Neutralization of Vaccinia Virus by Antibody to the A27 Protein and Protection of Mice against Intranasal Challenge
Christiana N. Fogg, Jeffrey L. Americo, Patricia L. Earl, Wolfgang Resch, Lydia Aldaz-Carroll, Roselyn J. Eisenberg, Gary H. Cohen, Bernard Moss
Vaccines and Antiviral Agents
DNA gag/Adenovirus Type 5 (Ad5) gag and Ad5 gag/Ad5 gag Vaccines Induce Distinct T-Cell Response Profiles
Kara S. Cox, James H. Clair, Michael T. Prokop, Kara J. Sykes, Sheri A. Dubey, John W. Shiver, Michael N. Robertson, Danilo R. Casimiro
Vaccines and Antiviral Agents | Spotlight
In Vivo Emergence of Vicriviroc Resistance in a Human Immunodeficiency Virus Type 1 Subtype C-Infected Subject
Athe M. N. Tsibris, Manish Sagar, Roy M. Gulick, Zhaohui Su, Michael Hughes, Wayne Greaves, Mani Subramanian, Charles Flexner, Françoise Giguel, Kay E. Leopold, Eoin Coakley, Daniel R. Kuritzkes

Letters to the Editor

Letters to the Editor
The First Chinese Porcine Sapovirus Strain That Contributed to an Outbreak of Gastroenteritis in Piglets
Wen Zhang, Quan Shen, Xiuguo Hua, Li Cui, Junfeng Liu, Shixing Yang
Letters to the Editor
When Should “I” Consider a New Hepatitis B Virus Genotype?
Fuat Kurbanov, Yasuhito Tanaka, Anna Kramvis, Peter Simmonds, Masashi Mizokami

Errata

ERRATA
Measles Virus Structural Components Are Enriched into Lipid Raft Microdomains: a Potential Cellular Location for Virus Assembly
Serge N. Manié, Sylvain de Breyne, Séverine Vincent, Denis Gerlier
ERRATA
Potential Transmission of Human Polyomaviruses through the Gastrointestinal Tract after Exposure to Virions or Viral DNA
Sílvia Bofill-Mas, Meritxell Formiga-Cruz, Pilar Clemente-Casares, Francesc Calafell, Rosina Girones

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Table of Contents

Spotlight

Virus-Cell Interactions

Pathogenesis and Immunity

Gene Delivery

Genetic Diversity and Evolution

Genome Replication and Regulation of Viral Gene Expression

Structure and Assembly

Transformation and Oncogenesis

Cellular Response to Infection

Vaccines and Antiviral Agents

Letters to the Editor

Errata

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