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Pathogenesis and Immunity

Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2

Jason Netland, David K. Meyerholz, Steven Moore, Martin Cassell, Stanley Perlman
Jason Netland
1Interdisciplinary Program in Immunology
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David K. Meyerholz
2Departments of Pathology
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Steven Moore
2Departments of Pathology
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Martin Cassell
3Anatomy and Cell Biology
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Stanley Perlman
1Interdisciplinary Program in Immunology
4 Microbiology, University of Iowa, Iowa City, Iowa 52242
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  • For correspondence: stanley-perlman@uiowa.edu
DOI: 10.1128/JVI.00737-08
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Article Information

DOI 
https://doi.org/10.1128/JVI.00737-08
PubMed 
18495771

Published By 
American Society for Microbiology Journals
History 
  • Received April 3, 2008
  • Accepted May 12, 2008
  • Published online July 11, 2008.

Copyright & Usage 
Copyright © 2008 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (May 21, 2008).
  • You are viewing the most recent version of this article.

Author Information

  1. Jason Netland1,
  2. David K. Meyerholz2,
  3. Steven Moore2,
  4. Martin Cassell3 and
  5. Stanley Perlman1,4*
  1. 1Interdisciplinary Program in Immunology
  2. 2Departments of Pathology
  3. 3Anatomy and Cell Biology
  4. 4 Microbiology, University of Iowa, Iowa City, Iowa 52242
  • ↵* Corresponding author. Mailing address: Department of Microbiology, University of Iowa, BSB 3-712, Iowa City, IA 52242. Phone: (319) 335-8549. Fax: (319) 335-9999. E-mail: stanley-perlman{at}uiowa.edu

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Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2
Jason Netland, David K. Meyerholz, Steven Moore, Martin Cassell, Stanley Perlman
Journal of Virology Jul 2008, 82 (15) 7264-7275; DOI: 10.1128/JVI.00737-08

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Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2
Jason Netland, David K. Meyerholz, Steven Moore, Martin Cassell, Stanley Perlman
Journal of Virology Jul 2008, 82 (15) 7264-7275; DOI: 10.1128/JVI.00737-08
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KEYWORDS

cell death
neurons
Peptidyl-Dipeptidase A
Receptors, Virus
SARS Virus
Severe Acute Respiratory Syndrome

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