Journal of Virology: 82 (13)

July 1, 2008; Volume 82,Issue 13

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Articles of Significant Interest Selected from This Issue by the Editors

Minireviews

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Alphaherpesviruses and Chemokines: Pas de Deux Not Yet Brought to Perfection
Gerlinde R. Van de Walle, Keith W. Jarosinski, Nikolaus Osterrieder

Virus-Cell Interactions

Virus-Cell Interactions
Cell-Type-Specific Tyrosine Phosphorylation of the Herpes Simplex Virus Tegument Protein VP11/12 Encoded by Gene UL46
George Zahariadis, Melany J. Wagner, Rosalyn C. Doepker, Jessica M. Maciejko, Carly M. Crider, Keith R. Jerome, James R. Smiley
Virus-Cell Interactions
Novel Postentry Resistance to AKV Ecotropic Mouse Gammaretroviruses in the African Pygmy Mouse, Mus minutoides
Yuhe Yan, Christine A. Kozak
Virus-Cell Interactions
Identification of a Physiological Phosphorylation Site of the Herpes Simplex Virus 1-Encoded Protein Kinase Us3 Which Regulates Its Optimal Catalytic Activity In Vitro and Influences Its Function in Infected Cells
Akihisa Kato, Michiko Tanaka, Mayuko Yamamoto, Risa Asai, Tetsutaro Sata, Yukihiro Nishiyama, Yasushi Kawaguchi
Virus-Cell Interactions
A New Role for ns Polyprotein Cleavage in Sindbis Virus Replication
Rodion Gorchakov, Elena Frolova, Stanley Sawicki, Svetlana Atasheva, Dorothea Sawicki, Ilya Frolov
Virus-Cell Interactions
Cytomegalovirus Proteins vMIA and m38.5 Link Mitochondrial Morphogenesis to Bcl-2 Family Proteins
Kristi L. Norris, Richard J. Youle
Virus-Cell Interactions
A Conserved Sequence within the H2 Subunit of the Vaccinia Virus Entry/Fusion Complex Is Important for Interaction with the A28 Subunit and Infectivity
Gretchen E. Nelson, Timothy R. Wagenaar, Bernard Moss
Virus-Cell Interactions
Bovine Papillomavirus Type 1: from Clathrin to Caveolin
Valerie Laniosz, Kirsten A. Holthusen, Patricio I. Meneses
Virus-Cell Interactions
Glycoproteins Required for Entry Are Not Necessary for Egress of Pseudorabies Virus
Barbara Klupp, Jan Altenschmidt, Harald Granzow, Walter Fuchs, Thomas C. Mettenleiter
Virus-Cell Interactions
Identification of a Critical Motif for the Human Immunodeficiency Virus Type 1 (HIV-1) gp41 Core Structure: Implications for Designing Novel Anti-HIV Fusion Inhibitors
Yuxian He, Jianwei Cheng, Jingjing Li, Zhi Qi, Hong Lu, Mingxin Dong, Shibo Jiang, Qiuyun Dai
Virus-Cell Interactions
Dendritic Cell Internalization of Foot-and-Mouth Disease Virus: Influence of Heparan Sulfate Binding on Virus Uptake and Induction of the Immune Response
Lisa J. Harwood, Heidi Gerber, Francisco Sobrino, Artur Summerfield, Kenneth C. McCullough
Virus-Cell Interactions
Nuclear Marginalization of Host Cell Chromatin Associated with Expansion of Two Discrete Virus-Induced Subnuclear Compartments during Baculovirus Infection
Toshihiro Nagamine, Yu Kawasaki, Atsushi Abe, Shogo Matsumoto
Virus-Cell Interactions
Cholesterol Effectively Blocks Entry of Flavivirus
Chyan-Jang Lee, Hui-Ru Lin, Ching-Len Liao, Yi-Ling Lin
Virus-Cell Interactions
Transcriptional Changes Induced by Bovine Papillomavirus Type 1 in Equine Fibroblasts
Z. Q. Yuan, L. Nicolson, B. Marchetti, E. A. Gault, M. S. Campo, L. Nasir
Virus-Cell Interactions
Critical Role for Endocytosis in the Regulation of Signaling by the Kaposi's Sarcoma-Associated Herpesvirus K1 Protein
Christine C. Tomlinson, Blossom Damania
Virus-Cell Interactions
Characterization of the Early Steps of Infection of Primary Blood Monocytes by Human Immunodeficiency Virus Type 1
Vanessa Arfi, Lise Rivière, Loraine Jarrosson-Wuillème, Caroline Goujon, Dominique Rigal, Jean-Luc Darlix, Andrea Cimarelli
Virus-Cell Interactions
Interactions of Murine APOBEC3 and Human APOBEC3G with Murine Leukemia Viruses
Samuel J. Rulli, Jane Mirro, Shawn A. Hill, Patricia Lloyd, Robert J. Gorelick, John M. Coffin, David Derse, Alan Rein
Virus-Cell Interactions
Small Interfering RNAs That Deplete the Cellular Translation Factor eIF4H Impede mRNA Degradation by the Virion Host Shutoff Protein of Herpes Simplex Virus
Nandini Sarma, Deepali Agarwal, Lora A. Shiflett, G. Sullivan Read
Virus-Cell Interactions
Molecular Basis of Cytotoxicity of Epstein-Barr Virus (EBV) Latent Membrane Protein 1 (LMP1) in EBV Latency III B Cells: LMP1 Induces Type II Ligand-Independent Autoactivation of CD95/Fas with Caspase 8-Mediated Apoptosis
Christophe Le Clorennec, Tan-Sothéa Ouk, Ibtissam Youlyouz-Marfak, Stéphanie Panteix, Catherine-Claude Martin, Julia Rastelli, Eric Adriaenssens, Ursula Zimber-Strobl, Jean Coll, Jean Feuillard, Chantal Jayat-Vignoles
Virus-Cell Interactions
Kaposi's Sarcoma-Associated Herpesvirus-Encoded LANA Can Interact with the Nuclear Mitotic Apparatus Protein To Regulate Genome Maintenance and Segregation
Huaxin Si, Subhash C. Verma, Michael A. Lampson, Qiliang Cai, Erle S. Robertson
Virus-Cell Interactions
Primate Lentivirus Capsid Sensitivity to TRIM5 Proteins
Zerina Kratovac, Cesar A. Virgen, Frederick Bibollet-Ruche, Beatrice H. Hahn, Paul D. Bieniasz, Theodora Hatziioannou

Structure and Assembly

Structure and Assembly
Mutations in the Amino Terminus of Foamy Virus Gag Disrupt Morphology and Infectivity but Do Not Target Assembly
Rachel B. Life, Eun-Gyung Lee, Scott W. Eastman, Maxine L. Linial
Structure and Assembly
A Filovirus-Unique Region of Ebola Virus Nucleoprotein Confers Aberrant Migration and Mediates Its Incorporation into Virions
Wei Shi, Yue Huang, Mark Sutton-Smith, Berangere Tissot, Maria Panico, Howard R. Morris, Anne Dell, Stuart M. Haslam, Jeffrey Boyington, Barney S. Graham, Zhi-Yong Yang, Gary J. Nabel
Structure and Assembly
Multimerization of Tegument Protein pp28 within the Assembly Compartment Is Required for Cytoplasmic Envelopment of Human Cytomegalovirus
Jun-Young Seo, William J. Britt
Structure and Assembly
Functional and Physical Interactions of the Herpes Simplex Virus Type 1 UL20 Membrane Protein with Glycoprotein K
Timothy P. Foster, Vladimir N. Chouljenko, K. G. Kousoulas
Structure and Assembly
Length Requirements for Membrane Fusion of Influenza Virus Hemagglutinin Peptide Linkers to Transmembrane or Fusion Peptide Domains
Zhu-Nan Li, Byeong-Jae Lee, William A. Langley, Konrad C. Bradley, Rupert J. Russell, David A. Steinhauer
Structure and Assembly
A Seven-Segmented Influenza A Virus Expressing the Influenza C Virus Glycoprotein HEF
Qinshan Gao, Edward W. A. Brydon, Peter Palese
Structure and Assembly
Laboratory Strains of Murine Cytomegalovirus Are Genetically Similar to but Phenotypically Distinct from Wild Strains of Virus
L. M. Smith, A. R. McWhorter, L. L. Masters, G. R. Shellam, A. J. Redwood
Structure and Assembly
Structural Analysis of Human Immunodeficiency Virus Type 1 CRF01_AE Protease in Complex with the Substrate p1-p6
Rajintha M. Bandaranayake, Moses Prabu-Jeyabalan, Junko Kakizawa, Wataru Sugiura, Celia A. Schiffer
Structure and Assembly
Amino Acids 143 to 150 of the Herpes Simplex Virus Type 1 Scaffold Protein Are Required for the Formation of Portal-Containing Capsids
Jamie B. Huffman, William W. Newcomb, Jay C. Brown, Fred L. Homa

Genome Replication and Regulation of Viral Gene Expression

Genome Replication and Regulation of Viral Gene Expression
Human Parainfluenza Virus Type 2 V Protein Inhibits Genome Replication by Binding to the L Protein: Possible Role in Promoting Viral Fitness
Machiko Nishio, Junpei Ohtsuka, Masato Tsurudome, Tetsuya Nosaka, Daniel Kolakofsky
Genome Replication and Regulation of Viral Gene Expression
Interaction between Polypeptide 3ABC and the 5′-Terminal Structural Elements of the Genome of Aichi Virus: Implication for Negative-Strand RNA Synthesis
Shigeo Nagashima, Jun Sasaki, Koki Taniguchi
Genome Replication and Regulation of Viral Gene Expression
Oligomerization of ICP4 and Rearrangement of Heat Shock Proteins May Be Important for Herpes Simplex Virus Type 1 Prereplicative Site Formation
Christine M. Livingston, Neal A. DeLuca, Dianna E. Wilkinson, Sandra K. Weller
Genome Replication and Regulation of Viral Gene Expression
Hypovirus Papain-Like Protease p48 Is Required for Initiation but Not for Maintenance of Virus RNA Propagation in the Chestnut Blight Fungus Cryphonectria parasitica
Fuyou Deng, Donald L. Nuss
Genome Replication and Regulation of Viral Gene Expression
RUNX1 Permits E4orf6-Directed Nuclear Localization of the Adenovirus E1B-55K Protein and Associates with Centers of Viral DNA and RNA Synthesis
Leslie J. Marshall, Amy C. Moore, Misao Ohki, Issay Kitabayashi, David Patterson, David A. Ornelles
Genome Replication and Regulation of Viral Gene Expression
Neutralizing Antibody Blocks Adenovirus Infection by Arresting Microtubule-Dependent Cytoplasmic Transport
Jason G. Smith, Aurelia Cassany, Larry Gerace, Robert Ralston, Glen R. Nemerow
Genome Replication and Regulation of Viral Gene Expression
Comparison of G-to-A Mutation Frequencies Induced by APOBEC3 Proteins in H9 Cells and Peripheral Blood Mononuclear Cells in the Context of Impaired Processivities of Drug-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Variants
Stefanie Andrea Knoepfel, Nadine Christina Salisch, Peter Michael Huelsmann, Pia Rauch, Hauke Walter, Karin Jutta Metzner
Genome Replication and Regulation of Viral Gene Expression
The UL25 Gene Product of Herpes Simplex Virus Type 1 Is Involved in Uncoating of the Viral Genome
Valerie G. Preston, Jill Murray, Christopher M. Preston, Iris M. McDougall, Nigel D. Stow
Genome Replication and Regulation of Viral Gene Expression
Generation of Recombinant Rotavirus with an Antigenic Mosaic of Cross-Reactive Neutralization Epitopes on VP4
Satoshi Komoto, Masanori Kugita, Jun Sasaki, Koki Taniguchi

Pathogenesis and Immunity

Pathogenesis and Immunity
Rotavirus Infection Accelerates Type 1 Diabetes in Mice with Established Insulitis
Kate L. Graham, Natalie Sanders, Yan Tan, Janette Allison, Thomas W. H. Kay, Barbara S. Coulson
Pathogenesis and Immunity
Priming of CD8⁺ T Cells during Central Nervous System Infection with a Murine Coronavirus Is Strain Dependent
Katherine C. MacNamara, Susan J. Bender, Ming Ming Chua, Richard Watson, Susan R. Weiss
Pathogenesis and Immunity
A Glycoconjugate Antigen Based on the Recognition Motif of a Broadly Neutralizing Human Immunodeficiency Virus Antibody, 2G12, Is Immunogenic but Elicits Antibodies Unable To Bind to the Self Glycans of gp120
Rena D. Astronomo, Hing-Ken Lee, Christopher N. Scanlan, Ralph Pantophlet, Cheng-Yuan Huang, Ian A. Wilson, Ola Blixt, Raymond A. Dwek, Chi-Huey Wong, Dennis R. Burton
Pathogenesis and Immunity
HLA Class I-Driven Evolution of Human Immunodeficiency Virus Type 1 Subtype C Proteome: Immune Escape and Viral Load
Christine M. Rousseau, Marcus G. Daniels, Jonathan M. Carlson, Carl Kadie, Hayley Crawford, Andrew Prendergast, Philippa Matthews, Rebecca Payne, Morgane Rolland, Dana N. Raugi, Brandon S. Maust, Gerald H. Learn, David C. Nickle, Hoosen Coovadia, Thumbi Ndung'u, Nicole Frahm, Christian Brander, Bruce D. Walker, Philip J. R. Goulder, Tanmoy Bhattacharya, David E. Heckerman, Bette T. Korber, James I. Mullins
Pathogenesis and Immunity
Human Cytomegalovirus Secretome Contains Factors That Induce Angiogenesis and Wound Healing
Jerome Dumortier, Daniel N. Streblow, Ashlee V. Moses, Jon M. Jacobs, Craig N. Kreklywich, David Camp, Richard D. Smith, Susan L. Orloff, Jay A. Nelson
Pathogenesis and Immunity
Citrus Tristeza Virus: Survival at the Edge of the Movement Continuum
Svetlana Y. Folimonova, Alexey S. Folimonov, Satyanarayana Tatineni, William O. Dawson
Pathogenesis and Immunity
Candidate Microbicide PPCM Blocks Human Immunodeficiency Virus Type 1 Infection in Cell and Tissue Cultures and Prevents Genital Herpes in a Murine Model
Pedro M. M. Mesquita, Sarah S. Wilson, Philippe Manlow, Lucia Fischetti, Marla J. Keller, Betsy C. Herold, Robin J. Shattock
Pathogenesis and Immunity
APOBEC3-Independent Interferon-Induced Viral Clearance in Hepatitis B Virus Transgenic Mice
Priscilla Turelli, Alexandra Liagre-Quazzola, Bastien Mangeat, Sonia Verp, Stephanie Jost, Didier Trono
Pathogenesis and Immunity
Antibody Is Critical for the Clearance of Murine Norovirus Infection
Karen A. Chachu, David W. Strong, Anna D. LoBue, Christiane E. Wobus, Ralph S. Baric, Herbert W. Virgin
Pathogenesis and Immunity
Antibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain II
Chih-Yun Lai, Wen-Yang Tsai, Su-Ru Lin, Chuan-Liang Kao, Hsien-Ping Hu, Chwan-Chuen King, Han-Chung Wu, Gwong-Jen Chang, Wei-Kung Wang
Pathogenesis and Immunity
Mutations in E2-PePHD, NS5A-PKRBD, NS5A-ISDR, and NS5A-V3 of Hepatitis C Virus Genotype 1 and Their Relationships to Pegylated Interferon-Ribavirin Treatment Responses
P. Muñoz de Rueda, J. Casado, R. Patón, D. Quintero, A. Palacios, A. Gila, R. Quiles, J. León, A. Ruiz-Extremera, J. Salmerón
Pathogenesis and Immunity
Hepatitis C Virus (HCV)-Induced Immunoglobulin Hypermutation Reduces the Affinity and Neutralizing Activities of Antibodies against HCV Envelope Protein
Keigo Machida, Yasuteru Kondo, Jeffrey Y. Huang, Yung-Chia Chen, Kevin T.-H. Cheng, Zhenyong Keck, Steven Foung, Jean Dubuisson, Vicky M.-H. Sung, Michael M. C. Lai
Pathogenesis and Immunity
In Vivo Natural Killer Cell Depletion during Primary Simian Immunodeficiency Virus Infection in Rhesus Monkeys
Elisa I. Choi, Keith A. Reimann, Norman L. Letvin
Pathogenesis and Immunity
Virus-Specific Interleukin-17-Producing CD4⁺ T Cells Are Detectable in Early Human Immunodeficiency Virus Type 1 Infection
Feng Yun Yue, Asad Merchant, Colin M. Kovacs, Mona Loutfy, Desmond Persad, Mario A. Ostrowski

Vaccines and Antiviral Agents

Vaccines and Antiviral Agents
Comparative Efficacy of Neutralizing Antibodies Elicited by Recombinant Hemagglutinin Proteins from Avian H5N1 Influenza Virus
Chih-Jen Wei, Ling Xu, Wing-Pui Kong, Wei Shi, Kevin Canis, James Stevens, Zhi-Yong Yang, Anne Dell, Stuart M. Haslam, Ian A. Wilson, Gary J. Nabel
Vaccines and Antiviral Agents
An Engineered Saccharomyces cerevisiae Strain Binds the Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody 2G12 and Elicits Mannose-Specific gp120-Binding Antibodies
Robert J. Luallen, Jianqiao Lin, Hu Fu, Karen K. Cai, Caroline Agrawal, Innocent Mboudjeka, Fang-Hua Lee, David Montefiori, David F. Smith, Robert W. Doms, Yu Geng
Vaccines and Antiviral Agents
Multifunctional T-Cell Characteristics Induced by a Polyvalent DNA Prime/Protein Boost Human Immunodeficiency Virus Type 1 Vaccine Regimen Given to Healthy Adults Are Dependent on the Route and Dose of Administration
Anju Bansal, Bethany Jackson, Kim West, Shixia Wang, Shan Lu, Jeffrey S. Kennedy, Paul A. Goepfert
Vaccines and Antiviral Agents
Incomplete Protection against Simian Immunodeficiency Virus Vaginal Transmission in Rhesus Macaques by a Topical Antiviral Agent Revealed by Repeat Challenges
Zandrea Ambrose, Lara Compton, Michael Piatak, Ding Lu, W. Gregory Alvord, Mariusz S. Lubomirski, James E. K. Hildreth, Jeffrey D. Lifson, Christopher J. Miller, Vineet N. KewalRamani
Vaccines and Antiviral Agents
Selection of T1249-Resistant Human Immunodeficiency Virus Type 1 Variants
Dirk Eggink, Christopher E. Baldwin, Yiqun Deng, Johannes P. M. Langedijk, Min Lu, Rogier W. Sanders, Ben Berkhout

Genetic Diversity and Evolution

Genetic Diversity and Evolution
Genetic Analysis of Israel Acute Paralysis Virus: Distinct Clusters Are Circulating in the United States
G. Palacios, J. Hui, P. L. Quan, A. Kalkstein, K. S. Honkavuori, A. V. Bussetti, S. Conlan, J. Evans, Y. P. Chen, D. vanEngelsdorp, H. Efrat, J. Pettis, D. Cox-Foster, E. C. Holmes, T. Briese, W. I. Lipkin
Genetic Diversity and Evolution
Rapid Sequence Change and Geographical Spread of Human Parvovirus B19: Comparison of B19 Virus Evolution in Acute and Persistent Infections
Päivi Norja, Anna Maria Eis-Hübinger, Maria Söderlund-Venermo, Klaus Hedman, Peter Simmonds
Genetic Diversity and Evolution
The Temperate Marine Phage ΦHAP-1 of Halomonas aquamarina Possesses a Linear Plasmid-Like Prophage Genome
Jennifer M. Mobberley, R. Nathan Authement, Anca M. Segall, John H. Paul
Genetic Diversity and Evolution
Impact of Endogenous Intronic Retroviruses on Major Histocompatibility Complex Class II Diversity and Stability
Gaby G. M. Doxiadis, Nanine de Groot, Ronald E. Bontrop
Genetic Diversity and Evolution
A Single Banana Streak Virus Integration Event in the Banana Genome as the Origin of Infectious Endogenous Pararetrovirus
Philippe Gayral, Juan-Carlos Noa-Carrazana, Magali Lescot, Fabrice Lheureux, Benham E. L. Lockhart, Takashi Matsumoto, Pietro Piffanelli, Marie-Line Iskra-Caruana
Genetic Diversity and Evolution
Construction and Characterization of a Human T-Cell Lymphotropic Virus Type 3 Infectious Molecular Clone
Sébastien Alain Chevalier, Nga Ling Ko, Sara Calattini, Adeline Mallet, Marie-Christine Prévost, Kylene Kehn, John N. Brady, Fatah Kashanchi, Antoine Gessain, Renaud Mahieux

Transformation and Oncogenesis

Transformation and Oncogenesis
Interferon Regulatory Factor 4 Is Involved in Epstein-Barr Virus-Mediated Transformation of Human B Lymphocytes
Dongsheng Xu, Lingjun Zhao, Luis Del Valle, Judith Miklossy, Luwen Zhang

Cellular Response to Infection

Cellular Response to Infection
Henipavirus V Protein Association with Polo-Like Kinase Reveals Functional Overlap with STAT1 Binding and Interferon Evasion
Louise E. Ludlow, Michael K. Lo, Jason J. Rodriguez, Paul A. Rota, Curt M. Horvath
Cellular Response to Infection
Autocrine and Paracrine Promotion of Cell Survival and Virus Replication by Human Herpesvirus 8 Chemokines
Young Bong Choi, John Nicholas

Letters to the Editor

LETTER TO THE EDITOR | Letter to the Editor | Letters to the Editor
Caution about Newcastle Disease Virus-Based Live Attenuated Vaccine
Guan-Zhu Han, Xi-Ping Liu, Si-Shen Li

Errata

Errata | Erratum
Hepatitis C Virus Genotype 1a Growth and Induction of Autophagy
Malika Ait-Goughoulte, Tatsuo Kanda, Keith Meyer, Jan S. Ryerse, Ratna B. Ray, Ranjit Ray
Errata | Erratum
Transcriptome Analysis of Infection of the Archaeon Sulfolobus solfataricus with Sulfolobus Turreted Icosahedral Virus
Alice C. Ortmann, Susan K. Brumfield, Jasper Walther, Kathleen McInnerney, Stan J. J. Brouns, Harmen J. G. van de Werken, Brian Bothner, Trevor Douglas, John van der Oost, Mark J. Young
Errata | Erratum
A Mutant of Sindbis Virus Which Is Able To Replicate in Cells with Reduced CTP Makes a Replicase/Transcriptase with a Decreased K_m for CTP
Mei-Ling Li, Yen-Huei Lin, H. Anne Simmonds, Victor Stollar

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Table of Contents

Spotlight

Minireviews

Virus-Cell Interactions

Structure and Assembly

Genome Replication and Regulation of Viral Gene Expression

Pathogenesis and Immunity

Vaccines and Antiviral Agents

Genetic Diversity and Evolution

Transformation and Oncogenesis

Cellular Response to Infection

Letters to the Editor

Errata

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