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Virus-Cell Interactions

Proteolytic Processing of the Ebola Virus Glycoprotein Is Not Critical for Ebola Virus Replication in Nonhuman Primates

Gabriele Neumann, Thomas W. Geisbert, Hideki Ebihara, Joan B. Geisbert, Kathleen M. Daddario-DiCaprio, Heinz Feldmann, Yoshihiro Kawaoka
Gabriele Neumann
1Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin—Madison, Madison, Wisconsin
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Thomas W. Geisbert
2United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland
3Uniformed Services University of the Health Sciences, Bethesda, Maryland
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Hideki Ebihara
4Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, and Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
5Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan
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Joan B. Geisbert
2United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland
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Kathleen M. Daddario-DiCaprio
2United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland
3Uniformed Services University of the Health Sciences, Bethesda, Maryland
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Heinz Feldmann
4Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, and Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
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Yoshihiro Kawaoka
1Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin—Madison, Madison, Wisconsin
5Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan
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  • For correspondence: kawaokay@svm.vetmed.wisc.edu
DOI: 10.1128/JVI.02486-06
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Article Information

DOI 
https://doi.org/10.1128/JVI.02486-06
PubMed 
17229700

Published By 
American Society for Microbiology Journals
History 
  • Received November 12, 2006
  • Accepted December 19, 2006
  • Published online February 23, 2007.

Copyright & Usage 
Copyright © 2007 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (January 17, 2007).
  • You are viewing the most recent version of this article.

Author Information

  1. Gabriele Neumann1,
  2. Thomas W. Geisbert2,3,
  3. Hideki Ebihara4,5,
  4. Joan B. Geisbert2,
  5. Kathleen M. Daddario-DiCaprio2,3,
  6. Heinz Feldmann4 and
  7. Yoshihiro Kawaoka1,5*
  1. 1Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin—Madison, Madison, Wisconsin
  2. 2United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland
  3. 3Uniformed Services University of the Health Sciences, Bethesda, Maryland
  4. 4Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, and Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
  5. 5Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan
  • ↵* Corresponding author. Mailing address: Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin—Madison, 2015 Linden Drive, Madison, WI 53706. Phone: (608) 265-4925. Fax: (608) 265-5622. E-mail: kawaokay{at}svm.vetmed.wisc.edu .

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Proteolytic Processing of the Ebola Virus Glycoprotein Is Not Critical for Ebola Virus Replication in Nonhuman Primates
Gabriele Neumann, Thomas W. Geisbert, Hideki Ebihara, Joan B. Geisbert, Kathleen M. Daddario-DiCaprio, Heinz Feldmann, Yoshihiro Kawaoka
Journal of Virology Feb 2007, 81 (6) 2995-2998; DOI: 10.1128/JVI.02486-06

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Proteolytic Processing of the Ebola Virus Glycoprotein Is Not Critical for Ebola Virus Replication in Nonhuman Primates
Gabriele Neumann, Thomas W. Geisbert, Hideki Ebihara, Joan B. Geisbert, Kathleen M. Daddario-DiCaprio, Heinz Feldmann, Yoshihiro Kawaoka
Journal of Virology Feb 2007, 81 (6) 2995-2998; DOI: 10.1128/JVI.02486-06
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KEYWORDS

ebolavirus
Protein Processing, Post-Translational
Viral Envelope Proteins
virus replication

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