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Pathogenesis and Immunity

Herpes Simplex Virus Type 1 and 2 Glycoprotein C Prevents Complement-Mediated Neutralization Induced by Natural Immunoglobulin M Antibody

Lauren M. Hook, John M. Lubinski, Ming Jiang, Michael K. Pangburn, Harvey M. Friedman
Lauren M. Hook
1Infectious Disease Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104
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John M. Lubinski
1Infectious Disease Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104
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Ming Jiang
1Infectious Disease Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104
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Michael K. Pangburn
2Department of Biochemistry, University of Texas Health Science Center, Tyler, Texas 75703
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Harvey M. Friedman
1Infectious Disease Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104
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  • For correspondence: hfriedma@mail.med.upenn.edu
DOI: 10.1128/JVI.80.8.4038-4046.2006
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Article Information

DOI 
https://doi.org/10.1128/JVI.80.8.4038-4046.2006
PubMed 
16571820

Published By 
American Society for Microbiology Journals
History 
  • Received October 19, 2005
  • Accepted January 27, 2006
  • Published online March 29, 2006.

Copyright & Usage 
Copyright © 2006 American Society for Microbiology

Author Information

  1. Lauren M. Hook1,
  2. John M. Lubinski1,
  3. Ming Jiang1,
  4. Michael K. Pangburn2 and
  5. Harvey M. Friedman1*
  1. 1Infectious Disease Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104
  2. 2Department of Biochemistry, University of Texas Health Science Center, Tyler, Texas 75703
  • ↵* Corresponding author. Mailing address: 502 Johnson Pavilion, University of Pennsylvania, Philadelphia, PA 19104-6073. Phone: (215) 662-3557. Fax: (215) 349-5111. E-mail: hfriedma{at}mail.med.upenn.edu .

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Herpes Simplex Virus Type 1 and 2 Glycoprotein C Prevents Complement-Mediated Neutralization Induced by Natural Immunoglobulin M Antibody
Lauren M. Hook, John M. Lubinski, Ming Jiang, Michael K. Pangburn, Harvey M. Friedman
Journal of Virology Mar 2006, 80 (8) 4038-4046; DOI: 10.1128/JVI.80.8.4038-4046.2006

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Herpes Simplex Virus Type 1 and 2 Glycoprotein C Prevents Complement-Mediated Neutralization Induced by Natural Immunoglobulin M Antibody
Lauren M. Hook, John M. Lubinski, Ming Jiang, Michael K. Pangburn, Harvey M. Friedman
Journal of Virology Mar 2006, 80 (8) 4038-4046; DOI: 10.1128/JVI.80.8.4038-4046.2006
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KEYWORDS

Antibodies, Viral
Complement System Proteins
Immunoglobulin M
Viral Envelope Proteins

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