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Genome Replication and Regulation of Viral Gene Expression

Phosphorylation of MCM4 at Sites Inactivating DNA Helicase Activity of the MCM4-MCM6-MCM7 Complex during Epstein-Barr Virus Productive Replication

Ayumi Kudoh, Tohru Daikoku, Yukio Ishimi, Yasushi Kawaguchi, Noriko Shirata, Satoko Iwahori, Hiroki Isomura, Tatsuya Tsurumi
Ayumi Kudoh
1Division of Virology, Aichi Cancer Center Research Institute, 1-1, Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan
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Tohru Daikoku
1Division of Virology, Aichi Cancer Center Research Institute, 1-1, Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan
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Yukio Ishimi
2Department of Materials and Biological Sciences, Faculty of Science, Ibaraki University, Mito 310-8512, Japan
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Yasushi Kawaguchi
3Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
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Noriko Shirata
1Division of Virology, Aichi Cancer Center Research Institute, 1-1, Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan
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Satoko Iwahori
1Division of Virology, Aichi Cancer Center Research Institute, 1-1, Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan
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Hiroki Isomura
1Division of Virology, Aichi Cancer Center Research Institute, 1-1, Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan
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Tatsuya Tsurumi
1Division of Virology, Aichi Cancer Center Research Institute, 1-1, Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan
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  • For correspondence: ttsurumi@aichi-cc.jp
DOI: 10.1128/JVI.00678-06
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Article Information

DOI 
https://doi.org/10.1128/JVI.00678-06
PubMed 
17005684

Published By 
American Society for Microbiology Journals
History 
  • Received April 4, 2006
  • Accepted July 25, 2006
  • Published online September 27, 2006.

Copyright & Usage 
Copyright © 2006 American Society for Microbiology

Author Information

  1. Ayumi Kudoh1,
  2. Tohru Daikoku1†,
  3. Yukio Ishimi2,
  4. Yasushi Kawaguchi3,
  5. Noriko Shirata1,
  6. Satoko Iwahori1,
  7. Hiroki Isomura1 and
  8. Tatsuya Tsurumi1*
  1. 1Division of Virology, Aichi Cancer Center Research Institute, 1-1, Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan
  2. 2Department of Materials and Biological Sciences, Faculty of Science, Ibaraki University, Mito 310-8512, Japan
  3. 3Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
  • ↵* Corresponding author. Mailing address: Division of Virology, Aichi Cancer Center Research Institute, 1-1, Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan. Phone and Fax: 81-52-764-2979. E-mail: ttsurumi{at}aichi-cc.jp .
  • ↵† Present address: Department of Virology, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.

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Phosphorylation of MCM4 at Sites Inactivating DNA Helicase Activity of the MCM4-MCM6-MCM7 Complex during Epstein-Barr Virus Productive Replication
Ayumi Kudoh, Tohru Daikoku, Yukio Ishimi, Yasushi Kawaguchi, Noriko Shirata, Satoko Iwahori, Hiroki Isomura, Tatsuya Tsurumi
Journal of Virology Sep 2006, 80 (20) 10064-10072; DOI: 10.1128/JVI.00678-06

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Phosphorylation of MCM4 at Sites Inactivating DNA Helicase Activity of the MCM4-MCM6-MCM7 Complex during Epstein-Barr Virus Productive Replication
Ayumi Kudoh, Tohru Daikoku, Yukio Ishimi, Yasushi Kawaguchi, Noriko Shirata, Satoko Iwahori, Hiroki Isomura, Tatsuya Tsurumi
Journal of Virology Sep 2006, 80 (20) 10064-10072; DOI: 10.1128/JVI.00678-06
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KEYWORDS

Cell Cycle Proteins
DNA Helicases
DNA-binding proteins
Herpesvirus 4, Human
Nuclear Proteins
virus replication

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