Induction of Multifunctional Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T Cells Capable of Proliferation in Healthy Subjects by Using a Prime-Boost Regimen of DNA- and Modified Vaccinia Virus Ankara-Vectored Vaccines Expressing HIV-1 Gag Coupled to CD8+ T-Cell Epitopes

Nilu Goonetilleke; Stephen Moore; Len Dally; Nicola Winstone; Inese Cebere; Abdul Mahmoud; Susana Pinheiro; Geraldine Gillespie; Denise Brown; Vanessa Loach; Joanna Roberts; Ana Guimaraes-Walker; Peter Hayes; Kelley Loughran; Carole Smith; Jan De Bont; Carl Verlinde; Danii Vooijs; Claudia Schmidt; Mark Boaz; Jill Gilmour; Pat Fast; Lucy Dorrell; Tomas Hanke; Andrew J. McMichael

doi:10.1128/JVI.80.10.4717-4728.2006

DOI: 10.1128/JVI.80.10.4717-4728.2006

Article Information

DOI

https://doi.org/10.1128/JVI.80.10.4717-4728.2006

PubMed

16641265

Published By

American Society for Microbiology Journals

History

Received November 22, 2005
Accepted March 2, 2006
Published online April 26, 2006.

American Society for Microbiology

Author Information

Nilu Goonetilleke1,*,
Stephen Moore1,
Len Dally2,
Nicola Winstone1,
Inese Cebere1,
Abdul Mahmoud1,
Susana Pinheiro1,
Geraldine Gillespie3,
Denise Brown1,
Vanessa Loach1,
Joanna Roberts1,
Ana Guimaraes-Walker1,
Peter Hayes4,
Kelley Loughran2,
Carole Smith2,
Jan De Bont5,
Carl Verlinde5,
Danii Vooijs5,
Claudia Schmidt5,
Mark Boaz5,
Jill Gilmour5,
Pat Fast5,
Lucy Dorrell1,
Tomas Hanke3, and
Andrew J. McMichael1,3

¹Centre for Clinical Vaccinology and Tropical Medicine
³MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford
⁴IAVI Core Laboratory, Imperial College, London, United Kingdom
²The EMMES Corporation, Rockville, Maryland
⁵International AIDS Vaccine Initiative, New York, New York

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