Genome Replication and Regulation of Viral Gene Expression

Alternate Polypurine Tracts (PPTs) Affect the Rous Sarcoma Virus RNase H Cleavage Specificity and Reveal a Preferential Cleavage following a GA Dinucleotide Sequence at the PPT-U3 Junction

Kevin W. Chang, John G. Julias, W. Gregory Alvord, Jangsuk Oh, Stephen H. Hughes
DOI: 10.1128/JVI.79.21.13694-13704.2005

Article Information

DOI 
https://doi.org/10.1128/JVI.79.21.13694-13704.2005
PubMed 
16227289
Published By 
American Society for Microbiology Journals
History 
  • Received May 2, 2005
  • Accepted August 3, 2005
  • Published online October 13, 2005.
Copyright & Usage 
Copyright © 2005 American Society for Microbiology

Author Information

  1. Kevin W. Chang1,
  2. John G. Julias1,2,
  3. W. Gregory Alvord3,
  4. Jangsuk Oh1 and
  5. Stephen H. Hughes1*
  1. 1HIV Drug Resistance Program, National Cancer Institute at Frederick, Frederick, Maryland
  2. 2Basic Research Program, SAIC-Frederick, Inc., Frederick, Maryland
  3. 3Data Management Services, National Cancer Institute at Frederick, Frederick, Maryland 21702-1201
  • ↵* Corresponding author. Mailing address: HIV Drug Resistance Program, NCI-Frederick, P.O. Box B, Bldg. 539, Rm. 130A, Frederick, MD 21702-1201. Phone: (301) 846-1619. Fax: (301) 846-6966. E-mail: hughes{at}ncifcrf.gov .

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KEYWORDS

Avian Sarcoma Viruses
Purines
Ribonuclease H

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