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Virus-Cell Interactions

Ternary Complex Formation of Human Immunodeficiency Virus Type 1 Env, CD4, and Chemokine Receptor Captured as an Intermediate of Membrane Fusion

Samvel R. Mkrtchyan, Ruben M. Markosyan, Michael T. Eadon, John P. Moore, Gregory B. Melikyan, Fredric S. Cohen
Samvel R. Mkrtchyan
1Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, Illinois 60612
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Ruben M. Markosyan
1Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, Illinois 60612
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Michael T. Eadon
1Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, Illinois 60612
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John P. Moore
2Department of Microbiology and Immunology, Weill Medical College, Cornell University, New York, New York 10021
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Gregory B. Melikyan
1Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, Illinois 60612
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Fredric S. Cohen
1Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, Illinois 60612
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  • For correspondence: fcohen@rush.edu
DOI: 10.1128/JVI.79.17.11161-11169.2005
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Article Information

DOI 
https://doi.org/10.1128/JVI.79.17.11161-11169.2005
PubMed 
16103167

Published By 
American Society for Microbiology Journals
History 
  • Received March 14, 2005
  • Accepted June 13, 2005
  • Published online August 15, 2005.

Copyright & Usage 
Copyright © 2005 American Society for Microbiology

Author Information

  1. Samvel R. Mkrtchyan1,
  2. Ruben M. Markosyan1,
  3. Michael T. Eadon1,
  4. John P. Moore2,
  5. Gregory B. Melikyan1 and
  6. Fredric S. Cohen1*
  1. 1Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, Illinois 60612
  2. 2Department of Microbiology and Immunology, Weill Medical College, Cornell University, New York, New York 10021
  • ↵* Corresponding author. Mailing address: Department of Molecular Biophysics and Physiology, Rush University Medical Center, 1653 W. Congress Pkwy., Chicago, IL 60612. Phone: (312) 942-6753. Fax: (312) 942-8711. E-mail: fcohen{at}rush.edu .
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Ternary Complex Formation of Human Immunodeficiency Virus Type 1 Env, CD4, and Chemokine Receptor Captured as an Intermediate of Membrane Fusion
Samvel R. Mkrtchyan, Ruben M. Markosyan, Michael T. Eadon, John P. Moore, Gregory B. Melikyan, Fredric S. Cohen
Journal of Virology Aug 2005, 79 (17) 11161-11169; DOI: 10.1128/JVI.79.17.11161-11169.2005

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Ternary Complex Formation of Human Immunodeficiency Virus Type 1 Env, CD4, and Chemokine Receptor Captured as an Intermediate of Membrane Fusion
Samvel R. Mkrtchyan, Ruben M. Markosyan, Michael T. Eadon, John P. Moore, Gregory B. Melikyan, Fredric S. Cohen
Journal of Virology Aug 2005, 79 (17) 11161-11169; DOI: 10.1128/JVI.79.17.11161-11169.2005
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KEYWORDS

CD4 Antigens
HIV Envelope Protein gp120
HIV Envelope Protein gp41
HIV-1
membrane fusion
Receptors, Chemokine

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