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Pathogenesis and Immunity

A Mutation in the HLA-B*2705-Restricted NP383-391 Epitope Affects the Human Influenza A Virus-Specific Cytotoxic T-Lymphocyte Response In Vitro

E. G. M. Berkhoff, A. C. M. Boon, N. J. Nieuwkoop, R. A. M. Fouchier, K. Sintnicolaas, A. D. M. E. Osterhaus, G. F. Rimmelzwaan
E. G. M. Berkhoff
1Institute of Virology
2WHO National Influenza Center, Erasmus Medical Center, Rotterdam
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A. C. M. Boon
1Institute of Virology
2WHO National Influenza Center, Erasmus Medical Center, Rotterdam
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N. J. Nieuwkoop
1Institute of Virology
2WHO National Influenza Center, Erasmus Medical Center, Rotterdam
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R. A. M. Fouchier
1Institute of Virology
2WHO National Influenza Center, Erasmus Medical Center, Rotterdam
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K. Sintnicolaas
3Laboratory for Histocompatibility and Immunogenetics, Sanquin Bloodbank, Dordrecht, The Netherlands
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A. D. M. E. Osterhaus
1Institute of Virology
2WHO National Influenza Center, Erasmus Medical Center, Rotterdam
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G. F. Rimmelzwaan
1Institute of Virology
2WHO National Influenza Center, Erasmus Medical Center, Rotterdam
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  • For correspondence: g.rimmelzwaan@erasmusmc.nl
DOI: 10.1128/JVI.78.10.5216-5222.2004
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Article Information

DOI 
https://doi.org/10.1128/JVI.78.10.5216-5222.2004
PubMed 
15113903

Published By 
American Society for Microbiology Journals
History 
  • Received November 13, 2003
  • Accepted January 16, 2004
  • Published online April 27, 2004.

Copyright & Usage 
Copyright © 2004 American Society for Microbiology

Author Information

  1. E. G. M. Berkhoff1,2,
  2. A. C. M. Boon1,2,
  3. N. J. Nieuwkoop1,2,
  4. R. A. M. Fouchier1,2,
  5. K. Sintnicolaas3,
  6. A. D. M. E. Osterhaus1,2 and
  7. G. F. Rimmelzwaan1,2*
  1. 1Institute of Virology
  2. 2WHO National Influenza Center, Erasmus Medical Center, Rotterdam
  3. 3Laboratory for Histocompatibility and Immunogenetics, Sanquin Bloodbank, Dordrecht, The Netherlands
  • ↵* Corresponding author. Mailing address: Institute of Virology, Erasmus Medical Center, P. O. Box 1738, 3000 DR Rotterdam, The Netherlands. Phone: 31 104088243. Fax: 31 104089485. E-mail: g.rimmelzwaan{at}erasmusmc.nl .

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A Mutation in the HLA-B*2705-Restricted NP383-391 Epitope Affects the Human Influenza A Virus-Specific Cytotoxic T-Lymphocyte Response In Vitro
E. G. M. Berkhoff, A. C. M. Boon, N. J. Nieuwkoop, R. A. M. Fouchier, K. Sintnicolaas, A. D. M. E. Osterhaus, G. F. Rimmelzwaan
Journal of Virology Apr 2004, 78 (10) 5216-5222; DOI: 10.1128/JVI.78.10.5216-5222.2004

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A Mutation in the HLA-B*2705-Restricted NP383-391 Epitope Affects the Human Influenza A Virus-Specific Cytotoxic T-Lymphocyte Response In Vitro
E. G. M. Berkhoff, A. C. M. Boon, N. J. Nieuwkoop, R. A. M. Fouchier, K. Sintnicolaas, A. D. M. E. Osterhaus, G. F. Rimmelzwaan
Journal of Virology Apr 2004, 78 (10) 5216-5222; DOI: 10.1128/JVI.78.10.5216-5222.2004
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KEYWORDS

Epitopes, T-Lymphocyte
HLA-B Antigens
influenza A virus
Nucleoproteins
Peptide Fragments
RNA-binding proteins
T-Lymphocytes, Cytotoxic
Viral Core Proteins

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