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Vaccines and Antiviral Agents

Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene

Danilo R. Casimiro, Ling Chen, Tong-Ming Fu, Robert K. Evans, Michael J. Caulfield, Mary-Ellen Davies, Aimin Tang, Minchun Chen, Lingyi Huang, Virginia Harris, Daniel C. Freed, Keith A. Wilson, Sheri Dubey, De-Min Zhu, Denise Nawrocki, Henryk Mach, Robert Troutman, Lynne Isopi, Donna Williams, William Hurni, Zheng Xu, Jeffrey G. Smith, Su Wang, Xu Liu, Liming Guan, Romnie Long, Wendy Trigona, Gwendolyn J. Heidecker, Helen C. Perry, Natasha Persaud, Timothy J. Toner, Qin Su, Xiaoping Liang, Rima Youil, Michael Chastain, Andrew J. Bett, David B. Volkin, Emilio A. Emini, John W. Shiver
Danilo R. Casimiro
1Departments of Viral Vaccine Research
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  • For correspondence: danilo_casimiro@merck.com
Ling Chen
1Departments of Viral Vaccine Research
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Tong-Ming Fu
1Departments of Viral Vaccine Research
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Robert K. Evans
2Vaccine Pharmaceutical Research and Development
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Michael J. Caulfield
3Virus and Cell Biology, Merck Research Laboratories, Merck and Company, West Point, Pennsylvania 19486
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Mary-Ellen Davies
1Departments of Viral Vaccine Research
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Aimin Tang
1Departments of Viral Vaccine Research
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Minchun Chen
1Departments of Viral Vaccine Research
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Lingyi Huang
1Departments of Viral Vaccine Research
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Virginia Harris
1Departments of Viral Vaccine Research
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Daniel C. Freed
1Departments of Viral Vaccine Research
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Keith A. Wilson
1Departments of Viral Vaccine Research
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Sheri Dubey
1Departments of Viral Vaccine Research
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De-Min Zhu
2Vaccine Pharmaceutical Research and Development
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Denise Nawrocki
2Vaccine Pharmaceutical Research and Development
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Henryk Mach
2Vaccine Pharmaceutical Research and Development
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Robert Troutman
2Vaccine Pharmaceutical Research and Development
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Lynne Isopi
2Vaccine Pharmaceutical Research and Development
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Donna Williams
2Vaccine Pharmaceutical Research and Development
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William Hurni
3Virus and Cell Biology, Merck Research Laboratories, Merck and Company, West Point, Pennsylvania 19486
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Zheng Xu
1Departments of Viral Vaccine Research
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Jeffrey G. Smith
3Virus and Cell Biology, Merck Research Laboratories, Merck and Company, West Point, Pennsylvania 19486
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Su Wang
3Virus and Cell Biology, Merck Research Laboratories, Merck and Company, West Point, Pennsylvania 19486
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Xu Liu
3Virus and Cell Biology, Merck Research Laboratories, Merck and Company, West Point, Pennsylvania 19486
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Liming Guan
1Departments of Viral Vaccine Research
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Romnie Long
1Departments of Viral Vaccine Research
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Wendy Trigona
1Departments of Viral Vaccine Research
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Gwendolyn J. Heidecker
1Departments of Viral Vaccine Research
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Helen C. Perry
1Departments of Viral Vaccine Research
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Natasha Persaud
1Departments of Viral Vaccine Research
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Timothy J. Toner
1Departments of Viral Vaccine Research
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Qin Su
1Departments of Viral Vaccine Research
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Xiaoping Liang
1Departments of Viral Vaccine Research
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Rima Youil
1Departments of Viral Vaccine Research
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Michael Chastain
1Departments of Viral Vaccine Research
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Andrew J. Bett
1Departments of Viral Vaccine Research
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David B. Volkin
1Departments of Viral Vaccine Research
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Emilio A. Emini
1Departments of Viral Vaccine Research
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John W. Shiver
1Departments of Viral Vaccine Research
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DOI: 10.1128/JVI.77.11.6305-6313.2003
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Article Information

DOI 
https://doi.org/10.1128/JVI.77.11.6305-6313.2003
PubMed 
12743287

Published By 
American Society for Microbiology Journals
History 
  • Received October 21, 2002
  • Accepted March 7, 2003
  • Published online June 1, 2003.

Copyright & Usage 
Copyright © 2003 American Society for Microbiology

Author Information

  1. Danilo R. Casimiro1*,
  2. Ling Chen1,
  3. Tong-Ming Fu1,
  4. Robert K. Evans2,
  5. Michael J. Caulfield3,
  6. Mary-Ellen Davies1,
  7. Aimin Tang1,
  8. Minchun Chen1,
  9. Lingyi Huang1,
  10. Virginia Harris1,
  11. Daniel C. Freed1,
  12. Keith A. Wilson1,
  13. Sheri Dubey1,
  14. De-Min Zhu2,
  15. Denise Nawrocki2,
  16. Henryk Mach2,
  17. Robert Troutman2,
  18. Lynne Isopi2,
  19. Donna Williams2,
  20. William Hurni3,
  21. Zheng Xu1,
  22. Jeffrey G. Smith3,
  23. Su Wang3,
  24. Xu Liu3,
  25. Liming Guan1,
  26. Romnie Long1,
  27. Wendy Trigona1,
  28. Gwendolyn J. Heidecker1,
  29. Helen C. Perry1,
  30. Natasha Persaud1,
  31. Timothy J. Toner1,
  32. Qin Su1,
  33. Xiaoping Liang1,
  34. Rima Youil1,
  35. Michael Chastain1,
  36. Andrew J. Bett1,
  37. David B. Volkin1,
  38. Emilio A. Emini1 and
  39. John W. Shiver1
  1. 1Departments of Viral Vaccine Research
  2. 2Vaccine Pharmaceutical Research and Development
  3. 3Virus and Cell Biology, Merck Research Laboratories, Merck and Company, West Point, Pennsylvania 19486
  • ↵* Corresponding author. Mailing address: Department of Viral Vaccine Research, Merck & Co., WP26-145, 770 Sumneytown Pike, West Point, PA 19486. Phone: (215) 652-3129. Fax: (215) 652-7320. E-mail: danilo_casimiro{at}merck.com .

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Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene
Danilo R. Casimiro, Ling Chen, Tong-Ming Fu, Robert K. Evans, Michael J. Caulfield, Mary-Ellen Davies, Aimin Tang, Minchun Chen, Lingyi Huang, Virginia Harris, Daniel C. Freed, Keith A. Wilson, Sheri Dubey, De-Min Zhu, Denise Nawrocki, Henryk Mach, Robert Troutman, Lynne Isopi, Donna Williams, William Hurni, Zheng Xu, Jeffrey G. Smith, Su Wang, Xu Liu, Liming Guan, Romnie Long, Wendy Trigona, Gwendolyn J. Heidecker, Helen C. Perry, Natasha Persaud, Timothy J. Toner, Qin Su, Xiaoping Liang, Rima Youil, Michael Chastain, Andrew J. Bett, David B. Volkin, Emilio A. Emini, John W. Shiver
Journal of Virology Jun 2003, 77 (11) 6305-6313; DOI: 10.1128/JVI.77.11.6305-6313.2003

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Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene
Danilo R. Casimiro, Ling Chen, Tong-Ming Fu, Robert K. Evans, Michael J. Caulfield, Mary-Ellen Davies, Aimin Tang, Minchun Chen, Lingyi Huang, Virginia Harris, Daniel C. Freed, Keith A. Wilson, Sheri Dubey, De-Min Zhu, Denise Nawrocki, Henryk Mach, Robert Troutman, Lynne Isopi, Donna Williams, William Hurni, Zheng Xu, Jeffrey G. Smith, Su Wang, Xu Liu, Liming Guan, Romnie Long, Wendy Trigona, Gwendolyn J. Heidecker, Helen C. Perry, Natasha Persaud, Timothy J. Toner, Qin Su, Xiaoping Liang, Rima Youil, Michael Chastain, Andrew J. Bett, David B. Volkin, Emilio A. Emini, John W. Shiver
Journal of Virology Jun 2003, 77 (11) 6305-6313; DOI: 10.1128/JVI.77.11.6305-6313.2003
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KEYWORDS

AIDS Vaccines
Genes, gag
Genetic Vectors
HIV Infections
Vaccines, DNA

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