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Virus-Cell Interactions

Interferon Regulatory Factor 3 Is a Cellular Partner of Rotavirus NSP1

Joel W. Graff, Dana N. Mitzel, Carla M. Weisend, Michelle L. Flenniken, Michele E. Hardy
Joel W. Graff
Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717
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Dana N. Mitzel
Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717
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Carla M. Weisend
Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717
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Michelle L. Flenniken
Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717
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Michele E. Hardy
Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717
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  • For correspondence: mhardy@montana.edu
DOI: 10.1128/JVI.76.18.9545-9550.2002
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Article Information

DOI 
https://doi.org/10.1128/JVI.76.18.9545-9550.2002
PubMed 
12186937

Published By 
American Society for Microbiology Journals
History 
  • Received March 11, 2002
  • Accepted June 12, 2002
  • Published online September 15, 2002.

Copyright & Usage 
Copyright © 2002 American Society for Microbiology

Author Information

  1. Joel W. Graff,
  2. Dana N. Mitzel,
  3. Carla M. Weisend,
  4. Michelle L. Flenniken and
  5. Michele E. Hardy*
  1. Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717
  • ↵* Corresponding author. Mailing address: Veterinary Molecular Biology, P.O. Box 173610, Montana State University, Bozeman, MT 59717. Phone: (406) 994-6378. Fax: (406) 994-4303. E-mail: mhardy{at}montana.edu .
  • † This article has been assigned journal number 2002-11 by the MAES.

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Interferon Regulatory Factor 3 Is a Cellular Partner of Rotavirus NSP1
Joel W. Graff, Dana N. Mitzel, Carla M. Weisend, Michelle L. Flenniken, Michele E. Hardy
Journal of Virology Sep 2002, 76 (18) 9545-9550; DOI: 10.1128/JVI.76.18.9545-9550.2002

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Interferon Regulatory Factor 3 Is a Cellular Partner of Rotavirus NSP1
Joel W. Graff, Dana N. Mitzel, Carla M. Weisend, Michelle L. Flenniken, Michele E. Hardy
Journal of Virology Sep 2002, 76 (18) 9545-9550; DOI: 10.1128/JVI.76.18.9545-9550.2002
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  • Top
  • Article
    • ABSTRACT
    • NSP1 interacts with IRF-3.
    • NSP1 synthesized in rotavirus-infected cells binds IRF-3.
    • The NSP1 zinc finger is important but not sufficient to mediate binding to IRF-3.
    • Role of NSP1-IRF-3 interaction in rotavirus-infected cells.
    • ACKNOWLEDGMENTS
    • FOOTNOTES
    • REFERENCES
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KEYWORDS

DNA-binding proteins
rotavirus
transcription factors
viral nonstructural proteins

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