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Virus-Cell Interactions

Herpes Simplex Virus Type 1 Blocks the Apoptotic Host Cell Defense Mechanisms That Target Bcl-2 and Manipulates Activation of p38 Mitogen-Activated Protein Kinase To Improve Viral Replication

George Zachos, Margy Koffa, Chris M. Preston, J. Barklie Clements, Joe Conner
George Zachos
Institute of Virology, University of Glasgow, and
School of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow G4 0BA, United Kingdom
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Margy Koffa
Institute of Virology, University of Glasgow, and
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Chris M. Preston
MRC Virology Unit, Institute of Virology, Glasgow G11 5JR, and
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J. Barklie Clements
Institute of Virology, University of Glasgow, and
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Joe Conner
School of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow G4 0BA, United Kingdom
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DOI: 10.1128/JVI.75.6.2710-2728.2001
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Article Information

DOI 
https://doi.org/10.1128/JVI.75.6.2710-2728.2001
PubMed 
11222695

Published By 
American Society for Microbiology Journals
History 
  • Received September 20, 2000
  • Accepted December 19, 2000
  • Published online March 15, 2001.

Copyright & Usage 
Copyright © 2001 American Society for Microbiology

Author Information

  1. George Zachos1,2†,
  2. Margy Koffa1,
  3. Chris M. Preston3,
  4. J. Barklie Clements1 and
  5. Joe Conner2*
  1. Institute of Virology, University of Glasgow,1 and
  2. MRC Virology Unit, Institute of Virology,3 Glasgow G11 5JR, and
  3. School of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow G4 0BA,2 United Kingdom
  • ↵* Corresponding author. Mailing address: School of Biological and Biomedical Sciences, Glasgow Caledonian University, Cowcaddens Rd., Glasgow G4 0BA, United Kingdom. Phone: (44 141) 331 3219. Fax: (44 141) 331 3208. E-mail:J.Conner{at}gcal.ac.uk.

  • ↵† Present address: CRC Beatson Institute for Cancer Research, Glasgow G61 1BD, United Kingdom.

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Herpes Simplex Virus Type 1 Blocks the Apoptotic Host Cell Defense Mechanisms That Target Bcl-2 and Manipulates Activation of p38 Mitogen-Activated Protein Kinase To Improve Viral Replication
George Zachos, Margy Koffa, Chris M. Preston, J. Barklie Clements, Joe Conner
Journal of Virology Mar 2001, 75 (6) 2710-2728; DOI: 10.1128/JVI.75.6.2710-2728.2001

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Herpes Simplex Virus Type 1 Blocks the Apoptotic Host Cell Defense Mechanisms That Target Bcl-2 and Manipulates Activation of p38 Mitogen-Activated Protein Kinase To Improve Viral Replication
George Zachos, Margy Koffa, Chris M. Preston, J. Barklie Clements, Joe Conner
Journal of Virology Mar 2001, 75 (6) 2710-2728; DOI: 10.1128/JVI.75.6.2710-2728.2001
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KEYWORDS

apoptosis
herpes simplex
Herpesvirus 1, Human
Mitogen-Activated Protein Kinases
Proto-Oncogene Proteins c-bcl-2

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