A Role for Perforin in Downregulating T-Cell Responses during Chronic Viral Infection

Mehrdad Matloubian; M. Suresh; Alison Glass; Marisa Galvan; Kit Chow; Jason K. Whitmire; Craig M. Walsh; William R. Clark; Rafi Ahmed

doi:10.1128/JVI.73.3.2527-2536.1999

DOI: 10.1128/JVI.73.3.2527-2536.1999

Article Information

DOI

https://doi.org/10.1128/JVI.73.3.2527-2536.1999

PubMed

9971838

Published By

American Society for Microbiology Journals

History

Received June 22, 1998
Accepted November 4, 1998
Published online March 1, 1999.

Author Information

Mehrdad Matloubian¹,
M. Suresh²,
Alison Glass³,
Marisa Galvan¹,
Kit Chow³,
Jason K. Whitmire²,
Craig M. Walsh³,
William R. Clark³ and
Rafi Ahmed² *

Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322,² and
Department of Microbiology and Immunology¹ and
Department of Biology and Molecular Biology Institute,³ University of California, Los Angeles, California 90024

↵* Corresponding author. Mailing address: Emory Vaccine Center, Emory University School of Medicine, G211 Rollins Research Center, 1510 Clifton Rd., Atlanta, GA 30322. Phone: (404) 727-3571. Fax: (404) 727-3722. E-mail: RA{at}microbio.emory.edu.

View Abstract

Article usage

Article usage: February 1999 to January 2021

Rendering graph...

	Abstract	Full	Pdf
Feb 1999	124	111	39
Mar 1999	49	67	21
Apr 1999	8	23	20
May 1999	5	9	4
Jun 1999	6	6	3
Jul 1999	1	12	3
Aug 1999	5	5	5
Sep 1999	1	8	7
Oct 1999	8	10	6
Nov 1999	4	10	20
Dec 1999	6	21	9
Jan 2000	4	22	10
Feb 2000	5	10	11
Mar 2000	4	13	31
Apr 2000	3	17	28
May 2000	3	12	23
Jun 2000	1	23	25
Jul 2000	3	15	24
Aug 2000	6	10	12
Sep 2000	2	6	10
Oct 2000	3	12	14
Nov 2000	11	24	45
Dec 2000	6	17	27
Jan 2001	9	22	25
Feb 2001	2	7	18
Mar 2001	0	20	20
Apr 2001	12	23	29
May 2001	3	17	14
Jun 2001	1	14	15
Jul 2001	7	10	17
Aug 2001	1	18	8
Sep 2001	7	14	8
Oct 2001	2	17	15
Nov 2001	0	11	16
Dec 2001	2	15	16
Jan 2002	2	12	18
Feb 2002	4	10	10
Mar 2002	1	9	14
Apr 2002	4	20	22
May 2002	1	10	20
Jun 2002	1	13	15
Jul 2002	2	12	11
Aug 2002	0	13	9
Sep 2002	1	22	14
Oct 2002	3	13	18
Nov 2002	1	8	12
Dec 2002	4	14	14
Jan 2003	5	31	31
Feb 2003	1	10	14
Mar 2003	1	19	15
Apr 2003	4	14	16
May 2003	3	8	7
Jun 2003	3	16	21
Jul 2003	4	14	11
Aug 2003	9	18	13
Sep 2003	12	23	10
Oct 2003	14	12	5
Nov 2003	18	19	8
Dec 2003	8	24	20
Jan 2004	14	24	8
Feb 2004	11	22	38
Mar 2004	12	46	28
Apr 2004	10	19	14
May 2004	12	23	14
Jun 2004	11	21	14
Jul 2004	14	20	19
Aug 2004	17	22	18
Sep 2004	14	23	10
Oct 2004	12	21	11
Nov 2004	18	20	29
Dec 2004	10	31	9
Jan 2005	12	27	34
Feb 2005	8	23	13
Mar 2005	12	26	19
Apr 2005	3	15	13
May 2005	13	25	20
Jun 2005	7	23	10
Jul 2005	7	21	9
Aug 2005	9	16	9
Sep 2005	4	16	13
Oct 2005	7	28	16
Nov 2005	7	17	3
Dec 2005	8	11	3
Jan 2006	6	18	10
Feb 2006	11	14	10
Mar 2006	9	14	14
Apr 2006	3	12	6
May 2006	7	16	15
Jun 2006	4	11	8
Jul 2006	5	11	14
Aug 2006	7	16	4
Sep 2006	6	21	8
Oct 2006	12	13	4
Nov 2006	16	17	4
Dec 2006	12	8	6
Jan 2007	9	14	13
Feb 2007	9	15	16
Mar 2007	14	22	9
Apr 2007	8	11	12
May 2007	6	11	5
Jun 2007	7	10	7
Jul 2007	13	12	7
Aug 2007	5	12	6
Sep 2007	6	10	6
Oct 2007	13	17	6
Nov 2007	9	13	5
Dec 2007	3	13	3
Jan 2008	7	12	8
Feb 2008	14	15	6
Mar 2008	16	29	6
Apr 2008	13	14	3
May 2008	12	23	11
Jun 2008	5	22	5
Jul 2008	4	9	8
Aug 2008	10	9	5
Sep 2008	7	7	12
Oct 2008	12	26	12
Nov 2008	4	6	2
Dec 2008	9	5	9
Jan 2009	5	5	5
Feb 2009	11	4	2
Mar 2009	6	13	6
Apr 2009	13	15	7
May 2009	8	5	6
Jun 2009	6	2	5
Jul 2009	7	13	6
Aug 2009	7	5	5
Sep 2009	7	4	5
Oct 2009	14	6	5
Nov 2009	10	9	8
Dec 2009	9	11	12
Jan 2010	13	8	7
Feb 2010	8	2	0
Mar 2010	8	3	4
Apr 2010	6	6	6
May 2010	1	10	4
Jun 2010	5	7	5
Jul 2010	6	7	3
Aug 2010	2	11	3
Sep 2010	6	10	1
Oct 2010	4	20	13
Nov 2010	15	10	2
Dec 2010	11	10	4
Jan 2011	7	16	13
Feb 2011	9	10	8
Mar 2011	16	13	11
Apr 2011	7	5	4
May 2011	15	10	11
Jun 2011	9	15	7
Jul 2011	8	5	3
Aug 2011	5	9	6
Sep 2011	7	4	2
Oct 2011	13	23	8
Nov 2011	14	9	12
Dec 2011	8	5	1
Jan 2012	12	8	7
Feb 2012	10	6	17
Mar 2012	9	4	9
Apr 2012	10	8	3
May 2012	4	4	6
Jun 2012	9	8	5
Jul 2012	8	15	11
Aug 2012	13	8	4
Sep 2012	12	6	5
Oct 2012	20	13	7
Nov 2012	22	7	7
Dec 2012	19	5	5
Jan 2013	25	11	3
Feb 2013	17	7	6
Mar 2013	44	9	6
Apr 2013	35	7	8
May 2013	17	15	9
Jun 2013	12	5	2
Jul 2013	18	3	4
Aug 2013	16	13	8
Sep 2013	4	9	3
Oct 2013	15	7	4
Nov 2013	8	5	3
Dec 2013	18	7	2
Jan 2014	10	7	2
Feb 2014	12	6	2
Mar 2014	18	8	4
Apr 2014	18	12	8
May 2014	24	17	6
Jun 2014	12	8	13
Jul 2014	28	16	5
Aug 2014	6	9	1
Sep 2014	28	16	10
Oct 2014	22	23	3
Nov 2014	16	16	11
Dec 2014	34	12	8
Jan 2015	27	7	2
Feb 2015	8	15	3
Mar 2015	20	18	10
Apr 2015	3	8	0
May 2015	19	7	2
Jun 2015	11	12	13
Jul 2015	34	26	3
Aug 2015	20	14	10
Sep 2015	19	15	8
Oct 2015	10	18	7
Nov 2015	14	16	6
Dec 2015	20	16	10
Jan 2016	22	76	11
Feb 2016	24	6	12
Mar 2016	24	8	9
Apr 2016	9	8	15
May 2016	14	5	12
Jun 2016	14	9	7
Jul 2016	10	15	11
Aug 2016	6	12	8
Sep 2016	12	10	5
Oct 2016	17	10	6
Nov 2016	7	12	3
Dec 2016	2	16	13
Jan 2017	7	13	8
Feb 2017	8	15	6
Mar 2017	9	11	5
Apr 2017	6	10	2
May 2017	5	15	4
Jun 2017	5	13	1
Jul 2017	10	16	13
Aug 2017	3	11	3
Sep 2017	8	13	2
Oct 2017	2	9	1
Nov 2017	4	10	2
Dec 2017	2	3	5
Jan 2018	3	2	2
Feb 2018	3	13	1
Mar 2018	3	14	5
Apr 2018	2	8	5
May 2018	16	14	12
Jun 2018	5	8	4
Jul 2018	3	10	8
Aug 2018	3	7	8
Sep 2018	6	4	9
Oct 2018	0	12	4
Nov 2018	1	14	4
Dec 2018	1	14	9
Jan 2019	1	9	5
Feb 2019	1	11	6
Mar 2019	0	14	7
Apr 2019	1	8	5
May 2019	5	23	4
Jun 2019	5	13	5
Jul 2019	0	17	5
Aug 2019	0	6	2
Sep 2019	0	18	11
Oct 2019	2	24	10
Nov 2019	6	23	8
Dec 2019	0	21	10
Jan 2020	3	43	13
Feb 2020	0	16	4
Mar 2020	3	12	13
Apr 2020	4	46	10
May 2020	1	54	11
Jun 2020	4	30	7
Jul 2020	4	32	19
Aug 2020	2	25	17
Sep 2020	3	22	8
Oct 2020	5	37	14
Nov 2020	10	34	20
Dec 2020	8	28	9
Jan 2021	5	14	12