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Multiple Posttranscriptional Strategies To Regulate the Herpes Simplex Virus 1 vhs Endoribonuclease
Structural and Molecular Characterization of the Hemagglutinin from the Fifth-Epidemic-Wave A(H7N9) Influenza Viruses

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Structure and Assembly

Structure and Assembly
Structural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus
Qingshan Lin, Tingting Li, Yixin Chen, Siu-Ying Lau, Minxi Wei, Yuyun Zhang, Zhenyong Zhang, Qiaobin Yao, Jinjin Li, Zhihai Li, Daning Wang, Qingbing Zheng, Hai Yu, Ying Gu, Jun Zhang, Honglin Chen, Shaowei Li, Ningshao Xia
Structure and Assembly
Dimerization of Coronavirus nsp9 with Diverse Modes Enhances Its Nucleic Acid Binding Affinity
Zhe Zeng, Feng Deng, Ke Shi, Gang Ye, Gang Wang, Liurong Fang, Shaobo Xiao, Zhenfang Fu, Guiqing Peng
Structure and Assembly
Dissecting the Herpesvirus Architecture by Targeted Proteolysis
Gina R. Daniel, Caitlin E. Pegg, Gregory A. Smith

Genome Replication and Regulation of Viral Gene Expression

Open Access

Genome Replication and Regulation of Viral Gene Expression
Transcriptional and Translational Landscape of Equine Torovirus
Hazel Stewart, Katherine Brown, Adam M. Dinan, Nerea Irigoyen, Eric J. Snijder, Andrew E. Firth
Genome Replication and Regulation of Viral Gene Expression
The Cellular Coactivator HCF-1 Is Required for Glucocorticoid Receptor-Mediated Transcription of Bovine Herpesvirus 1 Immediate Early Genes
Laximan Sawant, Insun Kook, Jodi L. Vogel, Thomas M. Kristie, Clinton Jones

Genetic Diversity and Evolution

Genetic Diversity and Evolution
A Single Mutation at Position 156 in the Envelope Protein of Tembusu Virus Is Responsible for Virus Tissue Tropism and Transmissibility in Ducks
Dawei Yan, Ying Shi, Haiwang Wang, Guoxin Li, Xuesong Li, Binbin Wang, Xin Su, Junheng Wang, Qiaoyang Teng, Jianmei Yang, Hongjun Chen, Qinfang Liu, Wenjun Ma, Zejun Li
Genetic Diversity and Evolution
Viral Discovery in the Invasive Australian Cane Toad (Rhinella marina) Using Metatranscriptomic and Genomic Approaches
Alice G. Russo, John-Sebastian Eden, Daniel Enosi Tuipulotu, Mang Shi, Daniel Selechnik, Richard Shine, Lee Ann Rollins, Edward C. Holmes, Peter A. White

Virus-Cell Interactions

Virus-Cell Interactions | Spotlight
Aedes Anphevirus: an Insect-Specific Virus Distributed Worldwide in Aedes aegypti Mosquitoes That Has Complex Interplays with Wolbachia and Dengue Virus Infection in Cells
Rhys Parry, Sassan Asgari
Virus-Cell Interactions
Transmembrane Domains Mediate Intra- and Extracellular Trafficking of Epstein-Barr Virus Latent Membrane Protein 1
Dingani Nkosi, Lauren A. Howell, Mujeeb R. Cheerathodi, Stephanie N. Hurwitz, Deanna C. Tremblay, Xia Liu, David G. Meckes
Virus-Cell Interactions | Spotlight
Expression of a Structural Protein of the Mycovirus FgV-ch9 Negatively Affects the Transcript Level of a Novel Symptom Alleviation Factor and Causes Virus Infection-Like Symptoms in Fusarium graminearum
Jörg Bormann, Cornelia Heinze, Christine Blum, Michael Mentges, Anke Brockmann, Arne Alder, Svenja Kim Landt, Brian Josephson, Daniela Indenbirken, Michael Spohn, Birte Plitzko, Sandra Loesgen, Michael Freitag, Wilhelm Schäfer
Virus-Cell Interactions
Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus
Cong-Cong Wu, Xuan Jiang, Xian-Zhang Wang, Xi-Juan Liu, Xiao-Jun Li, Bo Yang, Han-Qing Ye, Thomas Harwardt, Man Jiang, Hui-Min Xia, Wei Wang, William J. Britt, Christina Paulus, Michael Nevels, Min-Hua Luo
Virus-Cell Interactions | Spotlight
Axonal Transport Enables Neuron-to-Neuron Propagation of Human Coronavirus OC43
Mathieu Dubé, Alain Le Coupanec, Alan H. M. Wong, James M. Rini, Marc Desforges, Pierre J. Talbot
Virus-Cell Interactions
Role of MxB in Alpha Interferon-Mediated Inhibition of HIV-1 Infection
Bin Xu, Qinghua Pan, Chen Liang
Virus-Cell Interactions
Strand-Specific Dual RNA Sequencing of Bronchial Epithelial Cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions
Giulia Fabozzi, Andrew J. Oler, Poching Liu, Yong Chen, Samuel Mindaye, Michael A. Dolan, Heather Kenney, Marjan Gucek, Jun Zhu, Ronald L. Rabin, Kanta Subbarao
Virus-Cell Interactions
Efficient Genome Engineering of a Virulent Klebsiella Bacteriophage Using CRISPR-Cas9
Juntao Shen, Jinjie Zhou, Guo-Qiang Chen, Zhi-Long Xiu
Virus-Cell Interactions
Kaposi's Sarcoma-Associated Herpesvirus Nonstructural Membrane Protein pK15 Recruits the Class II Phosphatidylinositol 3-Kinase PI3K-C2α To Activate Productive Viral Replication
Bizunesh Abere, Naira Samarina, Silvia Gramolelli, Jessica Rückert, Gisa Gerold, Andreas Pich, Thomas F. Schulz
Virus-Cell Interactions
Reduced Susceptibility to VIRIP-Based HIV-1 Entry Inhibitors Has a High Genetic Barrier and Severe Fitness Costs
Janis A. Müller, Anna Glöckle, Ali Gawanbacht, Matthias Geyer, Jan Münch, Frank Kirchhoff
Virus-Cell Interactions
A Kaposi's Sarcoma-Associated Herpesvirus Infection Mechanism Is Independent of Integrins α3β1, αVβ3, and αVβ5
Allison Alwan TerBush, Florianne Hafkamp, Hee Jun Lee, Laurent Coscoy
Open Access

Virus-Cell Interactions | Spotlight
Multiple Posttranscriptional Strategies To Regulate the Herpes Simplex Virus 1 vhs Endoribonuclease
Gillian Elliott, Kathleen Pheasant, Katja Ebert-Keel, Julianna Stylianou, Ashley Franklyn, Juliet Jones
Virus-Cell Interactions
APOBEC3G-Regulated Host Factors Interfere with Measles Virus Replication: Role of REDD1 and Mammalian TORC1 Inhibition
Vishakha Tiwarekar, Julia Wohlfahrt, Markus Fehrholz, Claus-Jürgen Scholz, Susanne Kneitz, Jürgen Schneider-Schaulies
Virus-Cell Interactions
Rubella Viruses Shift Cellular Bioenergetics to a More Oxidative and Glycolytic Phenotype with a Strain-Specific Requirement for Glutamine
Nicole C. Bilz, Kristin Jahn, Mechthild Lorenz, Anja Lüdtke, Judith M. Hübschen, Henriette Geyer, Annette Mankertz, Denise Hübner, Uwe G. Liebert, Claudia Claus
Virus-Cell Interactions | Spotlight
Recurrent Loss of APOBEC3H Activity during Primate Evolution
Erin I. Garcia, Michael Emerman
Virus-Cell Interactions
The Methyltransferase-Like Domain of Chikungunya Virus nsP2 Inhibits the Interferon Response by Promoting the Nuclear Export of STAT1
Giel P. Göertz, Kristin L. McNally, Shelly J. Robertson, Sonja M. Best, Gorben P. Pijlman, Jelke J. Fros
Virus-Cell Interactions
Acidic pH Mediates Changes in Antigenic and Oligomeric Conformation of Herpes Simplex Virus gB and Is a Determinant of Cell-Specific Entry
Darin J. Weed, Stephen J. Dollery, Tri Komala Sari, Anthony V. Nicola
Virus-Cell Interactions
Human MxB Protein Is a Pan-herpesvirus Restriction Factor
Mirjam Schilling, Lorenzo Bulli, Sebastian Weigang, Laura Graf, Sebastian Naumann, Corinna Patzina, Valentina Wagner, Liane Bauersfeld, Caroline Goujon, Hartmut Hengel, Anne Halenius, Zsolt Ruzsics, Torsten Schaller, Georg Kochs

Cellular Response to Infection

Cellular Response to Infection
The Human Cytomegalovirus Protein UL148A Downregulates the NK Cell-Activating Ligand MICA To Avoid NK Cell Attack
Liat Dassa, Einat Seidel, Esther Oiknine-Djian, Rachel Yamin, Dana G. Wolf, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim

Gene Delivery

Gene Delivery
Cellular Antisilencing Elements Support Transgene Expression from Herpes Simplex Virus Vectors in the Absence of Immediate Early Gene Expression
Fang Han, Yoshitaka Miyagawa, Gianluca Verlengia, Selene Ingusci, Marie Soukupova, Michele Simonato, Joseph C. Glorioso, Justus B. Cohen

Vaccines and Antiviral Agents

Vaccines and Antiviral Agents
Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models
Penghui Li, Xianliang Ke, Ting Wang, Zhongyuan Tan, Dan Luo, Yuanjiu Miao, Jianhong Sun, Yuan Zhang, Yan Liu, Qinxue Hu, Fuqiang Xu, Hanzhong Wang, Zhenhua Zheng
Vaccines and Antiviral Agents
Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines
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Vaccines and Antiviral Agents
Murine Pneumonia Virus Expressing the Fusion Glycoprotein of Human Respiratory Syncytial Virus from an Added Gene Is Highly Attenuated and Immunogenic in Rhesus Macaques
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Neuraminidase-Inhibiting Antibody Titers Correlate with Protection from Heterologous Influenza Virus Strains of the Same Neuraminidase Subtype
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Attenuated Herpes Simplex Virus 1 (HSV-1) Expressing a Mutant Form of ICP6 Stimulates a Strong Immune Response That Protects Mice against HSV-1-Induced Corneal Disease
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Pathogenesis and Immunity

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Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques
Egidio Brocca-Cofano, Cuiling Xu, Katherine S. Wetzel, Mackenzie L. Cottrell, Benjamin B. Policicchio, Kevin D. Raehtz, Dongzhu Ma, Tammy Dunsmore, George S. Haret-Richter, Karam Musaitif, Brandon F. Keele, Angela D. Kashuba, Ronald G. Collman, Ivona Pandrea, Cristian Apetrei
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A Dual Motif in the Hemagglutinin of H5N1 Goose/Guangdong-Like Highly Pathogenic Avian Influenza Virus Strains Is Conserved from Their Early Evolution and Increases both Membrane Fusion pH and Virulence
Ute Wessels, Elsayed M. Abdelwhab, Jutta Veits, Donata Hoffmann, Svenja Mamerow, Olga Stech, Jan Hellert, Martin Beer, Thomas C. Mettenleiter, Jürgen Stech
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Regulation of Herpes Simplex Virus 2 Protein Kinase UL13 by Phosphorylation and Its Role in Viral Pathogenesis
Naoto Koyanagi, Akihisa Kato, Kosuke Takeshima, Yuhei Maruzuru, Hiroko Kozuka-Hata, Masaaki Oyama, Jun Arii, Yasushi Kawaguchi
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HIV-1 Subtype C-Infected Children with Exceptional Neutralization Breadth Exhibit Polyclonal Responses Targeting Known Epitopes
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Pathogenesis and Immunity
CD8⁺ T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress
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Author Corrections

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Author Correction
Correction for Chung et al., “Downregulation of Poly(ADP-Ribose) Polymerase 1 by a Viral Processivity Factor Facilitates Lytic Replication of Gammaherpesvirus”
Woo-Chang Chung, Joo-Hee Park, Hye-Ri Kang, Moon Jung Song
Open Access

Author Correction
Correction for Parolini et al., “Stability and Expression Levels of HLA-C on the Cell Membrane Modulate HIV-1 Infectivity”
Francesca Parolini, Priscilla Biswas, Michela Serena, Francesca Sironi, Valentina Muraro, Elisabetta Guizzardi, Lucia Cazzoletti, Maria Teresa Scupoli, Davide Gibellini, Elisabetta Ugolotti, Roberto Biassoni, Alberto Beretta, Mauro Malnati, Maria Grazia Romanelli, Donato Zipeto

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