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Contents: March 2010, Volume 84, Issue 5        Spotlight        Minireviews        Genome Replication and Regulation of Viral Gene Expression        Virus-Cell Interactions        Transformation and Oncogenesis        Genetic Diversity and Evolution        Pathogenesis and Immunity        Vaccines and Antiviral Agents        Structure and Assembly

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Spotlight:

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Articles of Significant Interest Selected from This Issue by the Editors J. Virol. March 2010 84: 2187 [Full Text] [PDF] [Reprints and Permissions] FREE

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Minireviews:

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Early Events in Kaposi's Sarcoma-Associated Herpesvirus Infection of Target Cells Bala Chandran J. Virol. March 2010 84: 2188-2199; published ahead of print November 18, 2009, doi:10.1128/JVI.01334-09 [Abstract] [Full Text] [PDF] [Author Bios] [Reprints and Permissions]

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Genome Replication and Regulation of Viral Gene Expression:

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ICP27 Phosphorylation Site Mutants Are Defective in Herpes Simplex Virus 1 Replication and Gene Expression Santos Rojas, Kara A. Corbin-Lickfett, Laurimar Escudero-Paunetto, and Rozanne M. Sandri-Goldin J. Virol. March 2010 84: 2200-2211; published ahead of print December 16, 2009, doi:10.1128/JVI.00917-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Augmented Latent Membrane Protein 1 Expression from Epstein-Barr Virus Episomes with Minimal Terminal Repeats Allison M. Repic, Mingxia Shi, Rona S. Scott, and John W. Sixbey J. Virol. March 2010 84: 2236-2244; published ahead of print December 16, 2009, doi:10.1128/JVI.01972-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inhibition of Sterol Biosynthesis Reduces Tombusvirus Replication in Yeast and Plants Monika Sharma, Zsuzsanna Sasvari, and Peter D. Nagy J. Virol. March 2010 84: 2270-2281; published ahead of print December 16, 2009, doi:10.1128/JVI.02003-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Testing the Balanced Electrostatic Interaction Hypothesis of Hepatitis B Virus DNA Synthesis by Using an In Vivo Charge Rebalance Approach Pong Kian Chua, Fan-Mei Tang, Jyuan-Yuan Huang, Ching-Shu Suen, and Chiaho Shih J. Virol. March 2010 84: 2340-2351; published ahead of print December 16, 2009, doi:10.1128/JVI.01666-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Functions of the Alphavirus Nonstructural Protein nsP3 C-Terminal Region Margus Varjak, Eva Zusinaite, and Andres Merits J. Virol. March 2010 84: 2352-2364; published ahead of print December 16, 2009, doi:10.1128/JVI.01540-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Herpes Simplex Virus Type 1 Immediate-Early Protein ICP22 Is Required for VICE Domain Formation during Productive Viral Infection Thomas W. Bastian, Christine M. Livingston, Sandra K. Weller, and Stephen A. Rice J. Virol. March 2010 84: 2384-2394; published ahead of print December 23, 2009, doi:10.1128/JVI.01686-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Latent Origin of Replication of Epstein-Barr Virus Directs Viral Genomes to Active Regions of the Nucleus Manuel J. Deutsch, Elisabeth Ott, Peer Papior, and Aloys Schepers J. Virol. March 2010 84: 2533-2546; published ahead of print December 23, 2009, doi:10.1128/JVI.01909-09 [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Downregulation of a Chitin Deacetylase-Like Protein in Response to Baculovirus Infection and Its Application for Improving Baculovirus Infectivity Agata K. Jakubowska, Silvia Caccia, Karl H. Gordon, Juan Ferré, and Salvador Herrero J. Virol. March 2010 84: 2547-2555; published ahead of print December 23, 2009, doi:10.1128/JVI.01860-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Xenotropic Murine Leukemia Virus-Related Virus Establishes an Efficient Spreading Infection and Exhibits Enhanced Transcriptional Activity in Prostate Carcinoma Cells Jason J. Rodriguez and Stephen P. Goff J. Virol. March 2010 84: 2556-2562; published ahead of print December 16, 2009, doi:10.1128/JVI.01969-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions] OPEN ACCESS

Stability of Murine Cytomegalovirus Genome after In Vitro and In Vivo Passage Tammy P. Cheng, Mark C. Valentine, Jian Gao, Jeanette T. Pingel, and Wayne M. Yokoyama J. Virol. March 2010 84: 2623-2628; published ahead of print December 16, 2009, doi:10.1128/JVI.02142-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of Untranslated Regions in Regulation of Gene Expression, Replication, and Pathogenicity of Newcastle Disease Virus Expressing Green Fluorescent Protein Shin-Hee Kim and Siba K. Samal J. Virol. March 2010 84: 2629-2634; published ahead of print December 16, 2009, doi:10.1128/JVI.02049-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Virus-Cell Interactions:

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ICP27 Phosphorylation Site Mutants Display Altered Functional Interactions with Cellular Export Factors Aly/REF and TAP/NXF1 but Are Able To Bind Herpes Simplex Virus 1 RNA Kara A. Corbin-Lickfett, Santos Rojas, Ling Li, Melanie J. Cocco, and Rozanne M. Sandri-Goldin J. Virol. March 2010 84: 2212-2222; published ahead of print December 16, 2009, doi:10.1128/JVI.01388-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

HIV-1 Nef Inhibits Ruffles, Induces Filopodia, and Modulates Migration of Infected Lymphocytes Cinzia Nobile, Dominika Rudnicka, Milena Hasan, Nathalie Aulner, Françoise Porrot, Christophe Machu, Olivier Renaud, Marie-Christine Prévost, Claire Hivroz, Olivier Schwartz, and Nathalie Sol-Foulon J. Virol. March 2010 84: 2282-2293; published ahead of print December 16, 2009, doi:10.1128/JVI.02230-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Conserved Motifs within Ebola and Marburg Virus VP40 Proteins Are Important for Stability, Localization, and Subsequent Budding of Virus-Like Particles Yuliang Liu, Luis Cocka, Atsushi Okumura, Yong-An Zhang, J. Oriol Sunyer, and Ronald N. Harty J. Virol. March 2010 84: 2294-2303; published ahead of print December 23, 2009, doi:10.1128/JVI.02034-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Latency-Associated Nuclear Antigen Interacts with MeCP2 and Nucleosomes through Separate Domains Satoko Matsumura, Linda M. Persson, LaiYee Wong, and Angus C. Wilson J. Virol. March 2010 84: 2318-2330; published ahead of print December 23, 2009, doi:10.1128/JVI.01097-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Proteomic Analysis of Interactions between a Deep-Sea Thermophilic Bacteriophage and Its Host at High Temperature Dahai Wei and Xiaobo Zhang J. Virol. March 2010 84: 2365-2373; published ahead of print December 16, 2009, doi:10.1128/JVI.02182-09 [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Infection of Cell Lines with Experimental and Natural Ovine Scrapie Agents Michael H. Neale, Susan J. Mountjoy, Jane C. Edwards, Didier Vilette, Hubert Laude, Otto Windl, and Ginny C. Saunders J. Virol. March 2010 84: 2444-2452; published ahead of print December 23, 2009, doi:10.1128/JVI.01855-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Sequestration of Free Tubulin Molecules by the Viral Protein NSP2 Induces Microtubule Depolymerization during Rotavirus Infection Davy Martin, Mariela Duarte, Jean Lepault, and Didier Poncet J. Virol. March 2010 84: 2522-2532; published ahead of print December 23, 2009, doi:10.1128/JVI.01883-09 [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

A Human Cytomegalovirus gO-Null Mutant Fails To Incorporate gH/gL into the Virion Envelope and Is Unable To Enter Fibroblasts and Epithelial and Endothelial Cells Paul T. Wille, Amber J. Knoche, Jay A. Nelson, Michael A. Jarvis, and David C. Johnson J. Virol. March 2010 84: 2585-2596; published ahead of print December 23, 2009, doi:10.1128/JVI.02249-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Cytomegalovirus TR Strain Glycoprotein O Acts as a Chaperone Promoting gH/gL Incorporation into Virions but Is Not Present in Virions Brent J. Ryckman, Marie C. Chase, and David C. Johnson J. Virol. March 2010 84: 2597-2609; published ahead of print December 23, 2009, doi:10.1128/JVI.02256-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Transformation and Oncogenesis:

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Activation of the N-Terminally Truncated Form of the Stk Receptor Tyrosine Kinase Sf-Stk by Friend Virus-Encoded gp55 Is Mediated by Cysteine Residues in the Ecotropic Domain of gp55 and the Extracellular Domain of Sf-Stk Shihan He, Shuang Ni, Shailaja Hegde, Xin Wang, Daniel R. Sharda, Avery August, Robert F. Paulson, and Pamela A. Hankey J. Virol. March 2010 84: 2223-2235; published ahead of print December 16, 2009, doi:10.1128/JVI.02090-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Genetic Diversity and Evolution:

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Genetic and Pathobiologic Characterization of Pandemic H1N1 2009 Influenza Viruses from a Naturally Infected Swine Herd Hana M. Weingartl, Yohannes Berhane, Tamiko Hisanaga, James Neufeld, Helen Kehler, Carissa Emburry-Hyatt, Kathleen Hooper-McGreevy, Samantha Kasloff, Brett Dalman, Jan Bystrom, Soren Alexandersen, Yan Li, and John Pasick J. Virol. March 2010 84: 2245-2256; published ahead of print December 16, 2009, doi:10.1128/JVI.02118-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions] FREE

Compartmentalization and Clonal Amplification of HIV-1 Variants in the Cerebrospinal Fluid during Primary Infection Gretja Schnell, Richard W. Price, Ronald Swanstrom, and Serena Spudich J. Virol. March 2010 84: 2395-2407; published ahead of print December 16, 2009, doi:10.1128/JVI.01863-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Vaccinia Virus Particles Mix Inefficiently, and in a Way That Would Restrict Viral Recombination, in Coinfected Cells Y.-C. James Lin and D. H. Evans J. Virol. March 2010 84: 2432-2443; published ahead of print December 23, 2009, doi:10.1128/JVI.01998-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pathogenesis and Immunity:

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Genomewide Association Analysis of Respiratory Syncytial Virus Infection in Mice James M. Stark, M. Michael Barmada, Abby V. Winterberg, Nilanjana Majumber, William J. Gibbons, Jr., Marilyn A. Stark, Maureen A. Sartor, Mario Medvedovic, Jay Kolls, Kiflai Bein, Beena Mailaparambil, Marcus Krueger, Andrea Heinzmann, George D. Leikauf, and Daniel R. Prows J. Virol. March 2010 84: 2257-2269; published ahead of print December 16, 2009, doi:10.1128/JVI.00584-09 [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

A Systemic Neutrophil Response Precedes Robust CD8+ T-Cell Activation during Natural Respiratory Syncytial Virus Infection in Infants Michaël V. Lukens, Alma C. van de Pol, Frank E. J. Coenjaerts, Nicolaas J. G. Jansen, Vera M. Kamp, Jan L. L. Kimpen, John W. A. Rossen, Laurien H. Ulfman, Carline E. A. Tacke, Marco C. Viveen, Leo Koenderman, Tom F. W. Wolfs, and Grada M. van Bleek J. Virol. March 2010 84: 2374-2383; published ahead of print December 16, 2009, doi:10.1128/JVI.01807-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Contributions of the Avian Influenza Virus HA, NA, and M2 Surface Proteins to the Induction of Neutralizing Antibodies and Protective Immunity Baibaswata Nayak, Sachin Kumar, Joshua M. DiNapoli, Anandan Paldurai, Daniel R. Perez, Peter L. Collins, and Siba K. Samal J. Virol. March 2010 84: 2408-2420; published ahead of print December 23, 2009, doi:10.1128/JVI.02135-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Interferon Stimulator Mitochondrial Antiviral Signaling Protein Facilitates Cell Death by Disrupting the Mitochondrial Membrane Potential and by Activating Caspases Chia-Yi Yu, Ruei-Lin Chiang, Tsung-Hsien Chang, Ching-Len Liao, and Yi-Ling Lin J. Virol. March 2010 84: 2421-2431; published ahead of print December 23, 2009, doi:10.1128/JVI.02174-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Induction of Protective Immunity against Murine Gammaherpesvirus 68 Infection in the Absence of Viral Latency Qingmei Jia, Michael L. Freeman, Eric J. Yager, Ian McHardy, Leming Tong, DeeAnn Martinez-Guzman, Tammy Rickabaugh, Seungmin Hwang, Marcia A. Blackman, Ren Sun, and Ting-Ting Wu J. Virol. March 2010 84: 2453-2465; published ahead of print December 16, 2009, doi:10.1128/JVI.01543-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Evidence of Early B-Cell Dysregulation in Simian Immunodeficiency Virus Infection: Rapid Depletion of Naïve and Memory B-Cell Subsets with Delayed Reconstitution of the Naïve B-Cell Population David Kuhrt, Seth A. Faith, Amanda Leone, Mukta Rohankedkar, Donald L. Sodora, Louis J. Picker, and Kelly Stefano Cole J. Virol. March 2010 84: 2466-2476; published ahead of print December 23, 2009, doi:10.1128/JVI.01966-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

RNA-Dependent RNA Polymerase 6 Delays Accumulation and Precludes Meristem Invasion of a Viroid That Replicates in the Nucleus Francesco Di Serio, Angel-Emilio Martínez de Alba, Beatriz Navarro, Andreas Gisel, and Ricardo Flores J. Virol. March 2010 84: 2477-2489; published ahead of print December 16, 2009, doi:10.1128/JVI.02336-09 [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Human Leukocyte Antigen Class I Supertypes and HIV-1 Control in African Americans Aleksandr Lazaryan, Wei Song, Elena Lobashevsky, Jianming Tang, Sadeep Shrestha, Kui Zhang, Lytt I. Gardner, Janet M. McNicholl, Craig M. Wilson, Robert S. Klein, Anne Rompalo, Kenneth Mayer, Jack Sobel, Richard A. Kaslow for the HIV Epidemiology Research Study and Reaching for Excellence in Adolescent Care and Health Study J. Virol. March 2010 84: 2610-2617; published ahead of print December 23, 2009, doi:10.1128/JVI.01962-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Vaccines and Antiviral Agents:

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Multi-Low-Dose Mucosal Simian Immunodeficiency Virus SIVmac239 Challenge of Cynomolgus Macaques Immunized with "Hyperattenuated" SIV Constructs David O. Willer, Yongjun Guan, Mark A. Luscher, Bing Li, Rick Pilon, Jocelyn Fournier, Monique Parenteau, Mark A. Wainberg, Paul Sandstrom, and Kelly S. MacDonald J. Virol. March 2010 84: 2304-2317; published ahead of print December 23, 2009, doi:10.1128/JVI.01995-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Combined Administration with DNA Encoding Vesicular Stomatitis Virus G Protein Enhances DNA Vaccine Potency Chih-Ping Mao, Chien-Fu Hung, Tae Heung Kang, Liangmei He, Ya-Chea Tsai, Chao-Yi Wu, and T.-C. Wu J. Virol. March 2010 84: 2331-2339; published ahead of print December 16, 2009, doi:10.1128/JVI.01954-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Targeted Delivery of Small Interfering RNA to Human Dendritic Cells To Suppress Dengue Virus Infection and Associated Proinflammatory Cytokine Production Sandesh Subramanya, Sang-Soo Kim, Sojan Abraham, Jiahong Yao, Mukesh Kumar, Priti Kumar, Viraga Haridas, Sang-Kyung Lee, Leonard D. Shultz, Dale Greiner, Manjunath N, and Premlata Shankar J. Virol. March 2010 84: 2490-2501; published ahead of print December 16, 2009, doi:10.1128/JVI.02105-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae Barry R. O'Keefe, Barbara Giomarelli, Dale L. Barnard, Shilpa R. Shenoy, Paul K. S. Chan, James B. McMahon, Kenneth E. Palmer, Brian W. Barnett, David K. Meyerholz, Christine L. Wohlford-Lenane, and Paul B. McCray, Jr. J. Virol. March 2010 84: 2511-2521; published ahead of print December 23, 2009, doi:10.1128/JVI.02322-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Potent Anti-HIV Activity of CXCL12 Correlates with Efficient CXCR4 Binding and Internalization Jeffrey D. Altenburg, Qingwen Jin, Bashar Alkhatib, and Ghalib Alkhatib J. Virol. March 2010 84: 2563-2572; published ahead of print December 16, 2009, doi:10.1128/JVI.00342-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Immunogenicity of Subtype A Human Immunodeficiency Virus Type 1 Envelope Exhibiting Differential Exposure of Conserved Neutralization Epitopes Catherine A. Blish, D. Noah Sather, George Sellhorn, Leonidas Stamatatos, Yide Sun, Indresh Srivastava, Susan W. Barnett, Brad Cleveland, Julie Overbaugh, and Shiu-lok Hu J. Virol. March 2010 84: 2573-2584; published ahead of print December 16, 2009, doi:10.1128/JVI.01687-09 [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Regulation of Porcine Endogenous Retrovirus Release by Porcine and Human Tetherins Giada Mattiuzzo, Sabrina Ivol, and Yasuhiro Takeuchi J. Virol. March 2010 84: 2618-2622; published ahead of print December 16, 2009, doi:10.1128/JVI.01928-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Structure and Assembly:

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The Structure of the Poxvirus A33 Protein Reveals a Dimer of Unique C-Type Lectin-Like Domains Hua-Poo Su, Kavita Singh, Apostolos G. Gittis, and David N. Garboczi J. Virol. March 2010 84: 2502-2510; published ahead of print December 23, 2009, doi:10.1128/JVI.02247-09 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.