Cover photograph (Copyright © 2009, American Society for Microbiology. All Rights Reserved.): Solanum sarrachoides (hairy nightshade) leaves infected with the phloem-limited Potato leafroll virus (PLRV) (left), or a PLRV mutant that is unable to translate the C-terminal half of its P5 protein (right). When the entire P5 protein is translated, the virus (purple-stained areas) is confined to the vascular tissue (left inset). However, when the P5 C terminus is not translated, the virus can move out of the phloem and infect mesophyll tissue (right inset). The C-terminal half of the P5 protein functions as a unique restrictive movement protein, limiting virus to the phloem. We thank Kent Loeffler for assembling these images. (See related article on p. 5419.)
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