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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2008 82: 2605. [Full Text] [PDF] FREE  

Cellular Response to Infection:

Sutapa Banerjee, Kousuke Saito, Malika Ait-Goughoulte, Keith Meyer, Ratna B. Ray, and Ranjit Ray

Hepatitis C Virus Core Protein Upregulates Serine Phosphorylation of Insulin Receptor Substrate-1 and Impairs the Downstream Akt/Protein Kinase B Signaling Pathway for Insulin Resistance
J. Virol. 2008 82: 2606-2612. [Abstract] [Full Text] [PDF]  

April J. Schumacher, Guylaine Haché, Donna A. MacDuff, William L. Brown, and Reuben S. Harris

The DNA Deaminase Activity of Human APOBEC3G Is Required for Ty1, MusD, and Human Immunodeficiency Virus Type 1 Restriction
J. Virol. 2008 82: 2652-2660. [Abstract] [Full Text] [PDF]  

John M. Ngunjiri, Margaret J. Sekellick, and Philip I. Marcus

Clonogenic Assay of Type A Influenza Viruses Reveals Noninfectious Cell-Killing (Apoptosis-Inducing) Particles
J. Virol. 2008 82: 2673-2680. [Abstract] [Full Text] [PDF]  

Anne K. Zaiss, Matthew J. Cotter, Lindsay R. White, Sharon A. Clark, Norman C. W. Wong, V. Michael Holers, Jeffrey S. Bartlett, and Daniel A. Muruve

Complement Is an Essential Component of the Immune Response to Adeno-Associated Virus Vectors
J. Virol. 2008 82: 2727-2740. [Abstract] [Full Text] [PDF]  

W. Y. Lam, Julian W. Tang, Apple C. M. Yeung, Lawrence C. M. Chiu, Joseph J. Y. Sung, and Paul K. S. Chan

Avian Influenza Virus A/HK/483/97(H5N1) NS1 Protein Induces Apoptosis in Human Airway Epithelial Cells
J. Virol. 2008 82: 2741-2751. [Abstract] [Full Text] [PDF]  

Matthijs Kramer, Barbara M. Schulte, Liza W. J. Toonen, Paola M. Barral, Paul B. Fisher, Kjerstin H. W. Lanke, Jochem M. D. Galama, Frank J. M. van Kuppeveld, and Gosse J. Adema

Phagocytosis of Picornavirus-Infected Cells Induces an RNA-Dependent Antiviral State in Human Dendritic Cells
J. Virol. 2008 82: 2930-2937. [Abstract] [Full Text] [PDF]  

Virus-Cell Interactions:

Xuemin Zhang, Gert C. Segers, Qihong Sun, Fuyou Deng, and Donald L. Nuss

Characterization of Hypovirus-Derived Small RNAs Generated in the Chestnut Blight Fungus by an Inducible DCL-2-Dependent Pathway
J. Virol. 2008 82: 2613-2619. [Abstract] [Full Text] [PDF] [Supplemental material]  

Roger D. Everett, Carlos Parada, Philippe Gripon, Hüseyin Sirma, and Anne Orr

Replication of ICP0-Null Mutant Herpes Simplex Virus Type 1 Is Restricted by both PML and Sp100
J. Virol. 2008 82: 2661-2672. [Abstract] [Full Text] [PDF]  

Petros Bozidis, Chad D. Williamson, and Anamaris M. Colberg-Poley

Mitochondrial and Secretory Human Cytomegalovirus UL37 Proteins Traffic into Mitochondrion-Associated Membranes of Human Cells
J. Virol. 2008 82: 2715-2726. [Abstract] [Full Text] [PDF]  

Christine Winter, Christel Schwegmann-Wessels, Ulrich Neumann, and Georg Herrler

The Spike Protein of Infectious Bronchitis Virus Is Retained Intracellularly by a Tyrosine Motif
J. Virol. 2008 82: 2765-2771. [Abstract] [Full Text] [PDF]  

Dror Avisar, Alexey I. Prokhnevsky, and Valerian V. Dolja

Class VIII Myosins Are Required for Plasmodesmatal Localization of a Closterovirus Hsp70 Homolog
J. Virol. 2008 82: 2836-2843. [Abstract] [Full Text] [PDF]  

Megan W. Howard, Emily A. Travanty, Scott A. Jeffers, M. K. Smith, Sonia T. Wennier, Larissa B. Thackray, and Kathryn V. Holmes

Aromatic Amino Acids in the Juxtamembrane Domain of Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Are Important for Receptor-Dependent Virus Entry and Cell-Cell Fusion
J. Virol. 2008 82: 2883-2894. [Abstract] [Full Text] [PDF]  

Sylvain Huard, Robert T. Elder, Dong Liang, Ge Li, and Richard Y. Zhao

Human Immunodeficiency Virus Type 1 Vpr Induces Cell Cycle G₂ Arrest through Srk1/MK2-Mediated Phosphorylation of Cdc25
J. Virol. 2008 82: 2904-2917. [Abstract] [Full Text] [PDF]  

Susanne Rauch, Kati Pulkkinen, Kalle Saksela, and Oliver T. Fackler

Human Immunodeficiency Virus Type 1 Nef Recruits the Guanine Exchange Factor Vav1 via an Unexpected Interface into Plasma Membrane Microdomains for Association with p21-Activated Kinase 2 Activity
J. Virol. 2008 82: 2918-2929. [Abstract] [Full Text] [PDF]  

Emma C. Nilsson, Fariba Jamshidi, Susanne M. C. Johansson, M. Steven Oberste, and Niklas Arnberg

Sialic Acid Is a Cellular Receptor for Coxsackievirus A24 Variant, an Emerging Virus with Pandemic Potential
J. Virol. 2008 82: 3061-3068. [Abstract] [Full Text] [PDF]  

Melanie Galla, Axel Schambach, Greg J. Towers, and Christopher Baum

Cellular Restriction of Retrovirus Particle-Mediated mRNA Transfer
J. Virol. 2008 82: 3069-3077. [Abstract] [Full Text] [PDF]  

Shiv K. Gandhi, Janet D. Siliciano, Justin R. Bailey, Robert F. Siliciano, and Joel N. Blankson

Role of APOBEC3G/F-Mediated Hypermutation in the Control of Human Immunodeficiency Virus Type 1 in Elite Suppressors
J. Virol. 2008 82: 3125-3130. [Abstract] [Full Text] [PDF]  

Pathogenesis and Immunity:

Mulu Z. Tesfay, Jun Yin, Christina L. Gardner, Mikhail V. Khoretonenko, Nadejda L. Korneeva, Robert E. Rhoads, Kate D. Ryman, and William B. Klimstra

Alpha/Beta Interferon Inhibits Cap-Dependent Translation of Viral but Not Cellular mRNA by a PKR-Independent Mechanism
J. Virol. 2008 82: 2620-2630. [Abstract] [Full Text] [PDF]  

Brian H. Bird, César G. Albariño, Amy L. Hartman, Bobbie Rae Erickson, Thomas G. Ksiazek, and Stuart T. Nichol

Rift Valley Fever Virus Lacking the NSs and NSm Genes Is Highly Attenuated, Confers Protective Immunity from Virulent Virus Challenge, and Allows for Differential Identification of Infected and Vaccinated Animals
J. Virol. 2008 82: 2681-2691. [Abstract] [Full Text] [PDF]  

Amy L. Hartman, Brian H. Bird, Jonathan S. Towner, Zoi-Anna Antoniadou, Sherif R. Zaki, and Stuart T. Nichol

Inhibition of IRF-3 Activation by VP35 Is Critical for the High Level of Virulence of Ebola Virus
J. Virol. 2008 82: 2699-2704. [Abstract] [Full Text] [PDF]  

Haruo Fujisawa

Neutrophils Play an Essential Role in Cooperation with Antibody in both Protection against and Recovery from Pulmonary Infection with Influenza Virus in Mice
J. Virol. 2008 82: 2772-2783. [Abstract] [Full Text] [PDF]  

Anvita Kumar, Andrew Zloza, Randall T. Moon, Jeffrey Watts, Allan R. Tenorio, and Lena Al-Harthi

Active β-Catenin Signaling Is an Inhibitory Pathway for Human Immunodeficiency Virus Replication in Peripheral Blood Mononuclear Cells
J. Virol. 2008 82: 2813-2820. [Abstract] [Full Text] [PDF]  

Gabriela Turk, María Magdalena Gherardi, Natalia Laufer, Mónica Saracco, Renata Luzzi, Josephine H. Cox, Pedro Cahn, and Horacio Salomon

Magnitude, Breadth, and Functional Profile of T-Cell Responses during Human Immunodeficiency Virus Primary Infection with B and BF Viral Variants
J. Virol. 2008 82: 2853-2866. [Abstract] [Full Text] [PDF]  

Rong Ou, Menghua Zhang, Lei Huang, Richard A. Flavell, Pandelakis A. Koni, and Demetrius Moskophidis

Regulation of Immune Response and Inflammatory Reactions against Viral Infection by VCAM-1
J. Virol. 2008 82: 2952-2965. [Abstract] [Full Text] [PDF]  

Kevin B. Walsh, Melissa B. Lodoen, Robert A. Edwards, Lewis L. Lanier, and Thomas E. Lane

Evidence for Differential Roles for NKG2D Receptor Signaling in Innate Host Defense against Coronavirus-Induced Neurological and Liver Disease
J. Virol. 2008 82: 3021-3030. [Abstract] [Full Text] [PDF]  

Kevin B. Walsh, Lewis L. Lanier, and Thomas E. Lane

NKG2D Receptor Signaling Enhances Cytolytic Activity by Virus-Specific CD8⁺ T Cells: Evidence for a Protective Role in Virus-Induced Encephalitis
J. Virol. 2008 82: 3031-3044. [Abstract] [Full Text] [PDF]  

David J. Woollard, Gholamreza Haqshenas, Xuebin Dong, Bridget F. Pratt, Stephen J. Kent, and Eric J. Gowans

Virus-Specific T-Cell Immunity Correlates with Control of GB Virus B Infection in Marmosets
J. Virol. 2008 82: 3054-3060. [Abstract] [Full Text] [PDF]  

Karen Baur, Mathias Rauer, Kirsten Richter, Axel Pagenstecher, Jürgen Götz, Jürgen Hausmann, and Peter Staeheli

Antiviral CD8 T Cells Recognize Borna Disease Virus Antigen Transgenically Expressed in either Neurons or Astrocytes
J. Virol. 2008 82: 3099-3108. [Abstract] [Full Text] [PDF]  

Sarah E. Blutt, Kelly L. Warfield, Mary K. Estes, and Margaret E. Conner

Differential Requirements for T Cells in Viruslike Particle- and Rotavirus-Induced Protective Immunity
J. Virol. 2008 82: 3135-3138. [Abstract] [Full Text] [PDF]  

M. Quinn DeGottardi, Anke Specht, Benjamin Metcalf, Amitinder Kaur, Frank Kirchhoff, and David T. Evans

Selective Downregulation of Rhesus Macaque and Sooty Mangabey Major Histocompatibility Complex Class I Molecules by Nef Alleles of Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 2
J. Virol. 2008 82: 3139-3146. [Abstract] [Full Text] [PDF]  

Daniel Yerly, David Heckerman, Todd M. Allen, John V. Chisholm, III, Kellie Faircloth, Caitlyn H. Linde, Nicole Frahm, Joerg Timm, Werner J. Pichler, Andreas Cerny, and Christian Brander

Increased Cytotoxic T-Lymphocyte Epitope Variant Cross-Recognition and Functional Avidity Are Associated with Hepatitis C Virus Clearance
J. Virol. 2008 82: 3147-3153. [Abstract] [Full Text] [PDF]  

Victoria Kasprowicz, Julian Schulze zur Wiesch, Thomas Kuntzen, Brian E. Nolan, Steven Longworth, Andrew Berical, Jenna Blum, Cory McMahon, Laura L. Reyor, Nahel Elias, William W. Kwok, Barbara G. McGovern, Gordon Freeman, Raymond T. Chung, Paul Klenerman, Lia Lewis-Ximenez, Bruce D. Walker, Todd M. Allen, Arthur Y. Kim, and Georg M. Lauer

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8⁺ and CD4⁺ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome
J. Virol. 2008 82: 3154-3160. [Abstract] [Full Text] [PDF]  

Genome Replication and Regulation of Viral Gene Expression:

Shuhei Taguwa, Toru Okamoto, Takayuki Abe, Yoshio Mori, Tetsuro Suzuki, Kohji Moriishi, and Yoshiharu Matsuura

Human Butyrate-Induced Transcript 1 Interacts with Hepatitis C Virus NS5A and Regulates Viral Replication
J. Virol. 2008 82: 2631-2641. [Abstract] [Full Text] [PDF]  

Paola Blanchette, Kathrin Kindsmüller, Peter Groitl, Frédéric Dallaire, Thomas Speiseder, Philip E. Branton, and Thomas Dobner

Control of mRNA Export by Adenovirus E4orf6 and E1B55K Proteins during Productive Infection Requires E4orf6 Ubiquitin Ligase Activity
J. Virol. 2008 82: 2642-2651. [Abstract] [Full Text] [PDF]  

Vladimir Majerciak, Koji Yamanegi, Eric Allemand, Michael Kruhlak, Adrian R. Krainer, and Zhi-Ming Zheng

Kaposi's Sarcoma-Associated Herpesvirus ORF57 Functions as a Viral Splicing Factor and Promotes Expression of Intron-Containing Viral Lytic Genes in Spliceosome-Mediated RNA Splicing
J. Virol. 2008 82: 2792-2801. [Abstract] [Full Text] [PDF]  

Yan Wang, Hong Li, Qiyi Tang, Gerd G. Maul, and Yan Yuan

Kaposi's Sarcoma-Associated Herpesvirus ori-Lyt-Dependent DNA Replication: Involvement of Host Cellular Factors
J. Virol. 2008 82: 2867-2882. [Abstract] [Full Text] [PDF]  

Guanghui Yi and Cheng Kao

cis- and trans-Acting Functions of Brome Mosaic Virus Protein 1a in Genomic RNA1 Replication
J. Virol. 2008 82: 3045-3053. [Abstract] [Full Text] [PDF]  

Truus E. M. Abbink and Ben Berkhout

RNA Structure Modulates Splicing Efficiency at the Human Immunodeficiency Virus Type 1 Major Splice Donor
J. Virol. 2008 82: 3090-3098. [Abstract] [Full Text] [PDF]  

Vaccines and Antiviral Agents:

Qinshan Gao, Man-Seong Park, and Peter Palese

Expression of Transgenes from Newcastle Disease Virus with a Segmented Genome
J. Virol. 2008 82: 2692-2698. [Abstract] [Full Text] [PDF]  

Arumugam Balamurugan, Martha J. Lewis, Christina M. R. Kitchen, Michael N. Robertson, John W. Shiver, Eric S. Daar, Jacqueline Pitt, Ayub Ali, Hwee L. Ng, Judith S. Currier, and Otto O. Yang

Primary Human Immunodeficiency Virus Type 1 (HIV-1) Infection during HIV-1 Gag Vaccination
J. Virol. 2008 82: 2784-2791. [Abstract] [Full Text] [PDF]  

Karin Jasmijn von Eije, Olivier ter Brake, and Ben Berkhout

Human Immunodeficiency Virus Type 1 Escape Is Restricted When Conserved Genome Sequences Are Targeted by RNA Interference
J. Virol. 2008 82: 2895-2903. [Abstract] [Full Text] [PDF]  

Yong Gao, Michael A. Lobritz, Justin Roth, Measho Abreha, Kenneth N. Nelson, Immaculate Nankya, Dawn M. Moore-Dudley, Awet Abraha, Stanton L. Gerson, and Eric J. Arts

Targets of Small Interfering RNA Restriction during Human Immunodeficiency Virus Type 1 Replication
J. Virol. 2008 82: 2938-2951. [Abstract] [Full Text] [PDF]  

Petra Mooij, Sunita S. Balla-Jhagjhoorsingh, Gerrit Koopman, Niels Beenhakker, Patricia van Haaften, Ilona Baak, Ivonne G. Nieuwenhuis, Ivanela Kondova, Ralf Wagner, Hans Wolf, Carmen E. Gómez, José L. Nájera, Victoria Jiménez, Mariano Esteban, and Jonathan L. Heeney

Differential CD4⁺ versus CD8⁺ T-Cell Responses Elicited by Different Poxvirus-Based Human Immunodeficiency Virus Type 1 Vaccine Candidates Provide Comparable Efficacies in Primates
J. Virol. 2008 82: 2975-2988. [Abstract] [Full Text] [PDF] [Supplemental material]  

Transformation and Oncogenesis:

Dweepanita Das, Kirk Wojno, and Michael J. Imperiale

BK Virus as a Cofactor in the Etiology of Prostate Cancer in Its Early Stages
J. Virol. 2008 82: 2705-2714. [Abstract] [Full Text] [PDF]  

Structure and Assembly:

Sarah M. McDonald and John T. Patton

Molecular Characterization of a Subgroup Specificity Associated with the Rotavirus Inner Capsid Protein VP2
J. Virol. 2008 82: 2752-2764. [Abstract] [Full Text] [PDF]  

Xiao Jing Jiang, Barbara Adler, Kerstin Laib Sampaio, Margarete Digel, Gerhard Jahn, Nicole Ettischer, York-Dieter Stierhof, Laura Scrivano, Ulrich Koszinowski, Michael Mach, and Christian Sinzger

UL74 of Human Cytomegalovirus Contributes to Virus Release by Promoting Secondary Envelopment of Virions
J. Virol. 2008 82: 2802-2812. [Abstract] [Full Text] [PDF] [Supplemental material]  

John E. Carpenter, Jennifer A. Hutchinson, Wallen Jackson, and Charles Grose

Egress of Light Particles among Filopodia on the Surface of Varicella-Zoster Virus-Infected Cells
J. Virol. 2008 82: 2821-2835. [Abstract] [Full Text] [PDF]  

Sonia Libersou, Xavier Siebert, Malika Ouldali, Leandro F. Estrozi, Jorge Navaza, Annie Charpilienne, Pascale Garnier, Didier Poncet, and Jean Lepault

Geometric Mismatches within the Concentric Layers of Rotavirus Particles: a Potential Regulatory Switch of Viral Particle Transcription Activity
J. Virol. 2008 82: 2844-2852. [Abstract] [Full Text] [PDF]  

Dennis J. Pierro, Erik L. Powers, and Ken E. Olson

Genetic Determinants of Sindbis Virus Mosquito Infection Are Associated with a Highly Conserved Alphavirus and Flavivirus Envelope Sequence
J. Virol. 2008 82: 2966-2974. [Abstract] [Full Text] [PDF]  

Joseph A. Boscarino, Hillary L. Logan, Jason J. Lacny, and Thomas M. Gallagher

Envelope Protein Palmitoylations Are Crucial for Murine Coronavirus Assembly
J. Virol. 2008 82: 2989-2999. [Abstract] [Full Text] [PDF]  

Lisa A. Lopez, Ambere J. Riffle, Steven L. Pike, Douglas Gardner, and Brenda G. Hogue

Importance of Conserved Cysteine Residues in the Coronavirus Envelope Protein
J. Virol. 2008 82: 3000-3010. [Abstract] [Full Text] [PDF]  

Qinghua Wang, Feng Cheng, Mingyang Lu, Xia Tian, and Jianpeng Ma

Crystal Structure of Unliganded Influenza B Virus Hemagglutinin
J. Virol. 2008 82: 3011-3020. [Abstract] [Full Text] [PDF]  

Claus-Henning Nagel, Katinka Döhner, Mojgan Fathollahy, Tanja Strive, Eva Maria Borst, Martin Messerle, and Beate Sodeik

Nuclear Egress and Envelopment of Herpes Simplex Virus Capsids Analyzed with Dual-Color Fluorescence HSV1(17⁺)
J. Virol. 2008 82: 3109-3124. [Abstract] [Full Text] [PDF]  

Sue E. Delos, Matthew B. Brecher, Zaoying Chen, Deborah C. Melder, Mark J. Federspiel, and Judith M. White

Cysteines Flanking the Internal Fusion Peptide Are Required for the Avian Sarcoma/Leukosis Virus Glycoprotein To Mediate the Lipid Mixing Stage of Fusion with High Efficiency
J. Virol. 2008 82: 3131-3134. [Abstract] [Full Text] [PDF]  

Gene Delivery:

Aviva Joseph, Jian Hua Zheng, Antonia Follenzi, Teresa DiLorenzo, Kaori Sango, Jaime Hyman, Ken Chen, Alicja Piechocka-Trocha, Christian Brander, Erik Hooijberg, Dario A. Vignali, Bruce D. Walker, and Harris Goldstein

Lentiviral Vectors Encoding Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Receptor Genes Efficiently Convert Peripheral Blood CD8 T Lymphocytes into Cytotoxic T Lymphocytes with Potent In Vitro and In Vivo HIV-1-Specific Inhibitory Activity
J. Virol. 2008 82: 3078-3089. [Abstract] [Full Text] [PDF]  

Errata:

Hayley Crawford, Julia G. Prado, Alasdair Leslie, Stéphane Hué, Isobella Honeyborne, Sharon Reddy, Mary van der Stok, Zenele Mncube, Christian Brander, Christine Rousseau, James I. Mullins, Richard Kaslow, Paul Goepfert, Susan Allen, Eric Hunter, Joseph Mulenga, Photini Kiepiela, Bruce D. Walker, and Philip J. R. Goulder

Compensatory Mutation Partially Restores Fitness and Delays Reversion of Escape Mutation within the Immunodominant HLA-B*5703-Restricted Gag Epitope in Chronic Human Immunodeficiency Virus Type 1 Infection
J. Virol. 2008 82: 3161. [Full Text] [PDF]  

Author's Correction:

Chung-Pei Lee, Jen-Yang Chen, Jiin-Tarng Wang, Keiji Kimura, Ai Takemoto, Chih-Chung Lu, and Mei-Ru Chen

Epstein-Barr Virus BGLF4 Kinase Induces Premature Chromosome Condensation through Activation of Condensin and Topoisomerase II
J. Virol. 2008 82: 3162. [Full Text] [PDF]  

St. Patrick Reid, Charalampos Valmas, Osvaldo Martinez, Freddy Mauricio Sanchez, and Christopher F. Basler

Ebola Virus VP24 Proteins Inhibit the Interaction of NPI-1 Subfamily Karyopherin Proteins with Activated STAT1
J. Virol. 2008 82: 3163. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.