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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2008 82: 595. [Full Text] [PDF] FREE [Reprints and Permissions]  

Guest Commentaries:

Yiming Bao, Pavel Bolotov, Dmitry Dernovoy, Boris Kiryutin, Leonid Zaslavsky, Tatiana Tatusova, Jim Ostell, and David Lipman

The Influenza Virus Resource at the National Center for Biotechnology Information
J. Virol. 2008 82: 596-601. [Full Text] [PDF] [Reprints and Permissions]  

Virus-Cell Interactions:

Brian M. Sullivan and Laurent Coscoy

Downregulation of the T-Cell Receptor Complex and Impairment of T-Cell Activation by Human Herpesvirus 6 U24 Protein
J. Virol. 2008 82: 602-608. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Martine Aubert, Zheng Chen, Robin Lang, Chung H. Dang, Carla Fowler, Derek D. Sloan, and Keith R. Jerome

The Antiapoptotic Herpes Simplex Virus Glycoprotein J Localizes to Multiple Cellular Organelles and Induces Reactive Oxygen Species Formation
J. Virol. 2008 82: 617-629. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katrina M. Nolan, Andrea P. O. Jordan, and James A. Hoxie

Effects of Partial Deletions within the Human Immunodeficiency Virus Type 1 V3 Loop on Coreceptor Tropism and Sensitivity to Entry Inhibitors
J. Virol. 2008 82: 664-673. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eric Lazear, Andrea Carfi, J. Charles Whitbeck, Tina M. Cairns, Claude Krummenacher, Gary H. Cohen, and Roselyn J. Eisenberg

Engineered Disulfide Bonds in Herpes Simplex Virus Type 1 gD Separate Receptor Binding from Fusion Initiation and Viral Entry
J. Virol. 2008 82: 700-709. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yuji Isegawa, Yoichi Miyamoto, Yoshinari Yasuda, Katsunori Semi, Kenji Tsujimura, Rikiro Fukunaga, Atsushi Ohshima, Yasuhiro Horiguchi, Yoshihiro Yoneda, and Nakaba Sugimoto

Characterization of the Human Herpesvirus 6 U69 Gene Product and Identification of Its Nuclear Localization Signal
J. Virol. 2008 82: 710-718. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tanya A. Miura, Emily A. Travanty, Lauren Oko, Helle Bielefeldt-Ohmann, Susan R. Weiss, Nicole Beauchemin, and Kathryn V. Holmes

The Spike Glycoprotein of Murine Coronavirus MHV-JHM Mediates Receptor-Independent Infection and Spread in the Central Nervous Systems of Ceacam1a^–/– Mice
J. Virol. 2008 82: 755-763. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Maria D. Gainey, Patrick J. Dillon, Kimberly M. Clark, Mary J. Manuse, and Griffith D. Parks

Paramyxovirus-Induced Shutoff of Host and Viral Protein Synthesis: Role of the P and V Proteins in Limiting PKR Activation
J. Virol. 2008 82: 828-839. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ping Zhang, Bertram L. Jacobs, and Charles E. Samuel

Loss of Protein Kinase PKR Expression in Human HeLa Cells Complements the Vaccinia Virus E3L Deletion Mutant Phenotype by Restoration of Viral Protein Synthesis
J. Virol. 2008 82: 840-848. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. Begoña Ruiz-Argüello, Vincent P. Smith, Gabriele S. V. Campanella, Françoise Baleux, Fernando Arenzana-Seisdedos, Andrew D. Luster, and Antonio Alcami

An Ectromelia Virus Protein That Interacts with Chemokines through Their Glycosaminoglycan Binding Domain
J. Virol. 2008 82: 917-926. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Meg L. Flanagan, Jill Oldenburg, Therese Reignier, Nathalia Holt, Genevieve A. Hamilton, Vanessa K. Martin, and Paula M. Cannon

New World Clade B Arenaviruses Can Use Transferrin Receptor 1 (TfR1)-Dependent and -Independent Entry Pathways, and Glycoproteins from Human Pathogenic Strains Are Associated with the Use of TfR1
J. Virol. 2008 82: 938-948. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mariana Marin, Sheetal Golem, Kristine M. Rose, Susan L. Kozak, and David Kabat

Human Immunodeficiency Virus Type 1 Vif Functionally Interacts with Diverse APOBEC3 Cytidine Deaminases and Moves with Them between Cytoplasmic Sites of mRNA Metabolism
J. Virol. 2008 82: 987-998. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

W. M. Yeo, Yuji Isegawa, and Vincent T. K. Chow

The U95 Protein of Human Herpesvirus 6B Interacts with Human GRIM-19: Silencing of U95 Expression Reduces Viral Load and Abrogates Loss of Mitochondrial Membrane Potential
J. Virol. 2008 82: 1011-1020. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kei Sato, Jun Aoki, Naoko Misawa, Eriko Daikoku, Kouichi Sano, Yuetsu Tanaka, and Yoshio Koyanagi

Modulation of Human Immunodeficiency Virus Type 1 Infectivity through Incorporation of Tetraspanin Proteins
J. Virol. 2008 82: 1021-1033. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gary Chan, Elizabeth R. Bivins-Smith, M. Shane Smith, and Andrew D. Yurochko

Transcriptome Analysis of NF-B- and Phosphatidylinositol 3-Kinase-Regulated Genes in Human Cytomegalovirus-Infected Monocytes
J. Virol. 2008 82: 1040-1046. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Cellular Response to Infection:

Brenda L. Fredericksen, Brian C. Keller, Jamie Fornek, Michael G. Katze, and Michael Gale, Jr.

Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1
J. Virol. 2008 82: 609-616. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

M. Iqbal Faruk, Ana Eusebio-Cope, and Nobuhiro Suzuki

A Host Factor Involved in Hypovirus Symptom Expression in the Chestnut Blight Fungus, Cryphonectria parasitica
J. Virol. 2008 82: 740-754. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Gene Delivery:

Natalya Belousova, Galina Mikheeva, Juri Gelovani, and Victor Krasnykh

Modification of Adenovirus Capsid with a Designed Protein Ligand Yields a Gene Vector Targeted to a Major Molecular Marker of Cancer
J. Virol. 2008 82: 630-637. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dror Kolodkin-Gal, Gideon Zamir, Yair Edden, Eli Pikarsky, Alon Pikarsky, Hillel Haim, Yosef S. Haviv, and Amos Panet

Herpes Simplex Virus Type 1 Preferentially Targets Human Colon Carcinoma: Role of Extracellular Matrix
J. Virol. 2008 82: 999-1010. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pathogenesis and Immunity:

Yun Li, Bradley Cleveland, Igor Klots, Bruce Travis, Barbra A. Richardson, David Anderson, David Montefiori, Patricia Polacino, and Shiu-Lok Hu

Removal of a Single N-Linked Glycan in Human Immunodeficiency Virus Type 1 gp120 Results in an Enhanced Ability To Induce Neutralizing Antibody Responses
J. Virol. 2008 82: 638-651. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pritha Sen, William A. Charini, Ramu A. Subbramanian, Edwin R. Manuel, Marcelo J. Kuroda, Patrick A. Autissier, and Norman L. Letvin

Clonal Focusing of Epitope-Specific CD8⁺ T Lymphocytes in Rhesus Monkeys following Vaccination and Simian-Human Immunodeficiency Virus Challenge
J. Virol. 2008 82: 805-816. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rheba S. Bonaparte, Pamela S. Hair, Deepa Banthia, Dawn M. Marshall, Kenji M. Cunnion, and Neel K. Krishna

Human Astrovirus Coat Protein Inhibits Serum Complement Activation via C1, the First Component of the Classical Pathway
J. Virol. 2008 82: 817-827. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Juan P. Giraldo-Vela, Richard Rudersdorf, Chungwon Chung, Ying Qi, Lyle T. Wallace, Benjamin Bimber, Gretta J. Borchardt, Debra L. Fisk, Chrystal E. Glidden, John T. Loffredo, Shari M. Piaskowski, Jessica R. Furlott, Juan P. Morales-Martinez, Nancy A. Wilson, William M. Rehrauer, Jeffrey D. Lifson, Mary Carrington, and David I. Watkins

The Major Histocompatibility Complex Class II Alleles Mamu-DRB1*1003 and -DRB1*0306 Are Enriched in a Cohort of Simian Immunodeficiency Virus-Infected Rhesus Macaque Elite Controllers
J. Virol. 2008 82: 859-870. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Amjad Hussain, Clement Wesley, Mohammad Khalid, Ashutosh Chaudhry, and Shahid Jameel

Human Immunodeficiency Virus Type 1 Vpu Protein Interacts with CD74 and Modulates Major Histocompatibility Complex Class II Presentation
J. Virol. 2008 82: 893-902. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Milloni B. Patel, Noah G. Hoffman, and Ronald Swanstrom

Subtype-Specific Conformational Differences within the V3 Region of Subtype B and Subtype C Human Immunodeficiency Virus Type 1 Env Proteins
J. Virol. 2008 82: 903-916. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Atsushi Yamanaka, Saori Kosugi, and Eiji Konishi

Infection-Enhancing and -Neutralizing Activities of Mouse Monoclonal Antibodies against Dengue Type 2 and 4 Viruses Are Controlled by Complement Levels
J. Virol. 2008 82: 927-937. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lance K. Ching, Giorgos Vlachogiannis, Katherine A. Bosch, and Leonidas Stamatatos

The First Hypervariable Region of the gp120 Env Glycoprotein Defines the Neutralizing Susceptibility of Heterologous Human Immunodeficiency Virus Type 1 Isolates to Neutralizing Antibodies Elicited by the SF162gp140 Immunogen
J. Virol. 2008 82: 949-956. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jean-Christophe Meunier, Rodney S. Russell, Vera Goossens, Sofie Priem, Hugo Walter, Erik Depla, Ann Union, Kristina N. Faulk, Jens Bukh, Suzanne U. Emerson, and Robert H. Purcell

Isolation and Characterization of Broadly Neutralizing Human Monoclonal Antibodies to the E1 Glycoprotein of Hepatitis C Virus
J. Virol. 2008 82: 966-973. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Adrian Valli, Gabriela Dujovny, and Juan Antonio García

Protease Activity, Self Interaction, and Small Interfering RNA Binding of the Silencing Suppressor P1b from Cucumber Vein Yellowing Ipomovirus
J. Virol. 2008 82: 974-986. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Mario Perotti, Nicasio Mancini, Roberta A. Diotti, Alexander W. Tarr, Jonathan K. Ball, Ania Owsianka, R. Adair, Arvind H. Patel, Massimo Clementi, and Roberto Burioni

Identification of a Broadly Cross-Reacting and Neutralizing Human Monoclonal Antibody Directed against the Hepatitis C Virus E2 Protein
J. Virol. 2008 82: 1047-1052. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wai-Hong Wu and Andrew Pekosz

Extending the Cytoplasmic Tail of the Influenza A Virus M2 Protein Leads to Reduced Virus Replication In Vivo but Not In Vitro
J. Virol. 2008 82: 1059-1063. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vaccines and Antiviral Agents:

D. Huw Davies, Linda S. Wyatt, Frances K. Newman, Patricia L. Earl, Sookhee Chun, Jenny E. Hernandez, Douglas M. Molina, Siddiqua Hirst, Bernard Moss, Sharon E. Frey, and Philip L. Felgner

Antibody Profiling by Proteome Microarray Reveals the Immunogenicity of the Attenuated Smallpox Vaccine Modified Vaccinia Virus Ankara Is Comparable to That of Dryvax
J. Virol. 2008 82: 652-663. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Kazuya Shimura, Eiichi Kodama, Yasuko Sakagami, Yuji Matsuzaki, Wataru Watanabe, Kazunobu Yamataka, Yasuo Watanabe, Yoshitsugu Ohata, Satoki Doi, Motohide Sato, Mitsuki Kano, Satoru Ikeda, and Masao Matsuoka

Broad Antiretroviral Activity and Resistance Profile of the Novel Human Immunodeficiency Virus Integrase Inhibitor Elvitegravir (JTK-303/GS-9137)
J. Virol. 2008 82: 764-774. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Patrick Lacasse, Jérôme Denis, Réjean Lapointe, Denis Leclerc, and Alain Lamarre

Novel Plant Virus-Based Vaccine Induces Protective Cytotoxic T-Lymphocyte-Mediated Antiviral Immunity through Dendritic Cell Maturation
J. Virol. 2008 82: 785-794. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Structure and Assembly:

Xin Zhang, Todd J. Green, Jun Tsao, Shihong Qiu, and Ming Luo

Role of Intermolecular Interactions of Vesicular Stomatitis Virus Nucleoprotein in RNA Encapsidation
J. Virol. 2008 82: 674-682. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Scott P. Kenney, Timothy L. Lochmann, Cullen L. Schmid, and Leslie J. Parent

Intermolecular Interactions between Retroviral Gag Proteins in the Nucleus
J. Virol. 2008 82: 683-691. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Genome Replication and Regulation of Viral Gene Expression:

Wen-Hung Huang, Yen-Shun Chen, and Pei-Jer Chen

Nucleolar Targeting of Hepatitis Delta Antigen Abolishes Its Ability To Initiate Viral Antigenomic RNA Replication
J. Virol. 2008 82: 692-699. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jangsuk Oh, Mary Jane McWilliams, John G. Julias, and Stephen H. Hughes

Mutations in the U5 Region Adjacent to the Primer Binding Site Affect tRNA Cleavage by Human Immunodeficiency Virus Type 1 Reverse Transcriptase In Vivo
J. Virol. 2008 82: 719-727. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Masaki Imai, Kazunori Kawasaki, and Takato Odagiri

Cytoplasmic Domain of Influenza B Virus BM2 Protein Plays Critical Roles in Production of Infectious Virus
J. Virol. 2008 82: 728-739. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jianrong Li, Amal Rahmeh, Marco Morelli, and Sean P. J. Whelan

A Conserved Motif in Region V of the Large Polymerase Proteins of Nonsegmented Negative-Sense RNA Viruses That Is Essential for mRNA Capping
J. Virol. 2008 82: 775-784. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yoshiaki Yamagishi, Tomohiko Sadaoka, Hironori Yoshii, Pranee Somboonthum, Takayoshi Imazawa, Kazuhiro Nagaike, Keiichi Ozono, Koichi Yamanishi, and Yasuko Mori

Varicella-Zoster Virus Glycoprotein M Homolog Is Glycosylated, Is Expressed on the Viral Envelope, and Functions in Virus Cell-to-Cell Spread
J. Virol. 2008 82: 795-804. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hiroki Isomura, Mark F. Stinski, Ayumi Kudoh, Sanae Nakayama, Takayuki Murata, Yoshitaka Sato, Satoko Iwahori, and Tatsuya Tsurumi

A cis Element between the TATA Box and the Transcription Start Site of the Major Immediate-Early Promoter of Human Cytomegalovirus Determines Efficiency of Viral Replication
J. Virol. 2008 82: 849-858. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nicole L. Garneau, Kevin J. Sokoloski, Mateusz Opyrchal, C. Preston Neff, Carol J. Wilusz, and Jeffrey Wilusz

The 3' Untranslated Region of Sindbis Virus Represses Deadenylation of Viral Transcripts in Mosquito and Mammalian Cells
J. Virol. 2008 82: 880-892. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Transformation and Oncogenesis:

Vojtech Sroller, Regis A. Vilchez, A. Renee Stewart, Connie Wong, and Janet S. Butel

Influence of the Viral Regulatory Region on Tumor Induction by Simian Virus 40 in Hamsters
J. Virol. 2008 82: 871-879. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vera L. Tarakanova, Friederike Kreisel, Douglas W. White, and Herbert W. Virgin, IV

Murine Gammaherpesvirus 68 Genes both Induce and Suppress Lymphoproliferative Disease
J. Virol. 2008 82: 1034-1039. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Samina Alam, Michael J. Conway, Horng-Shen Chen, and Craig Meyers

The Cigarette Smoke Carcinogen Benzo[a]pyrene Enhances Human Papillomavirus Synthesis
J. Virol. 2008 82: 1053-1058. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Genetic Diversity and Evolution:

Siobain Duffy and Edward C. Holmes

Phylogenetic Evidence for Rapid Rates of Molecular Evolution in the Single-Stranded DNA Begomovirus Tomato Yellow Leaf Curl Virus
J. Virol. 2008 82: 957-965. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.