About This Cover Other Issues

Contents: July 2008, Volume 82, Issue 14        Spotlight        Structure and Assembly        Cellular Response to Infection        Pathogenesis and Immunity        Vaccines and Antiviral Agents        Genome Replication and Regulation of Viral Gene Expression        Virus-Cell Interactions        Gene Delivery        Genetic Diversity and Evolution        Author's Correction

Table of Contents

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Spotlight:

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Articles of Significant Interest Selected from This Issue by the Editors J. Virol. July 2008 82: 6787 [Full Text] [PDF] [Reprints and Permissions]

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Structure and Assembly:

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Mutations in the Spacer Peptide and Adjoining Sequences in Rous Sarcoma Virus Gag Lead to Tubular Budding Paul W. Keller, Marc C. Johnson, and Volker M. Vogt J. Virol. July 2008 82: 6788-6797; published ahead of print April 30, 2008, doi:10.1128/JVI.00213-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Structural Analysis of Major Species Barriers between Humans and Palm Civets for Severe Acute Respiratory Syndrome Coronavirus Infections Fang Li J. Virol. July 2008 82: 6984-6991; published ahead of print April 30, 2008, doi:10.1128/JVI.00442-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficient trans-Encapsidation of Hepatitis C Virus RNAs into Infectious Virus-Like Particles Eike Steinmann, Christiane Brohm, Stephanie Kallis, Ralf Bartenschlager, and Thomas Pietschmann J. Virol. July 2008 82: 7034-7046; published ahead of print May 14, 2008, doi:10.1128/JVI.00118-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Small Capsid Protein pORF65 Is Essential for Assembly of Kaposi's Sarcoma-Associated Herpesvirus Capsids Edward M. Perkins, Daniel Anacker, Aaron Davis, Vishwam Sankar, Richard F. Ambinder, and Prashant Desai J. Virol. July 2008 82: 7201-7211; published ahead of print May 7, 2008, doi:10.1128/JVI.00423-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Cellular Response to Infection:

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Hepatitis B Virus HBx Protein Localizes to Mitochondria in Primary Rat Hepatocytes and Modulates Mitochondrial Membrane Potential Amy J. Clippinger and Michael J. Bouchard J. Virol. July 2008 82: 6798-6811; published ahead of print April 30, 2008, doi:10.1128/JVI.00154-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Functional Domains and the Antiviral Effect of the Double-Stranded RNA-Dependent Protein Kinase PKR from Paralichthys olivaceus Rong Zhu, Yi-Bing Zhang, Qi-Ya Zhang, and Jian-Fang Gui J. Virol. July 2008 82: 6889-6901; published ahead of print April 30, 2008, doi:10.1128/JVI.02385-07 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Hepatitis E Virus ORF3 Protein Modulates Epidermal Growth Factor Receptor Trafficking, STAT3 Translocation, and the Acute-Phase Response Vivek Chandra, Anindita Kar-Roy, Sudha Kumari, Satyajit Mayor, and Shahid Jameel J. Virol. July 2008 82: 7100-7110; published ahead of print April 30, 2008, doi:10.1128/JVI.00403-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pathogenesis and Immunity:

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Qualitative and Quantitative Characteristics of Rotavirus-Specific CD8 T Cells Vary Depending on the Route of Infection Janina Q. Jiang, Xiao-Song He, Ningguo Feng, and Harry B. Greenberg J. Virol. July 2008 82: 6812-6819; published ahead of print May 14, 2008, doi:10.1128/JVI.00450-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Annexin II Incorporated into Influenza Virus Particles Supports Virus Replication by Converting Plasminogen into Plasmin Fanny LeBouder, Eric Morello, Guus F. Rimmelzwaan, Françoise Bosse, Christine Péchoux, Bernard Delmas, and Béatrice Riteau J. Virol. July 2008 82: 6820-6828; published ahead of print April 30, 2008, doi:10.1128/JVI.00246-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro-Generated Antigen-Specific CD4+ CD25+ Foxp3+ Regulatory T Cells Control the Severity of Herpes Simplex Virus-Induced Ocular Immunoinflammatory Lesions Sharvan Sehrawat, Susmit Suvas, Pranita P. Sarangi, Amol Suryawanshi, and Barry T. Rouse J. Virol. July 2008 82: 6838-6851; published ahead of print May 14, 2008, doi:10.1128/JVI.00697-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cross-Reactive Human Immunodeficiency Virus Type 1-Neutralizing Human Monoclonal Antibody That Recognizes a Novel Conformational Epitope on gp41 and Lacks Reactivity against Self-Antigens Mei-Yun Zhang, Bang K. Vu, Anil Choudhary, Hong Lu, Michael Humbert, Helena Ong, Munir Alam, Ruth M. Ruprecht, Gerald Quinnan, Shibo Jiang, David C. Montefiori, John R. Mascola, Christopher C. Broder, Barton F. Haynes, and Dimiter S. Dimitrov J. Virol. July 2008 82: 6869-6879; published ahead of print May 14, 2008, doi:10.1128/JVI.00033-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Blocking Antibody Access to Neutralizing Domains on Glycoproteins Involved in Entry as a Novel Mechanism of Immune Evasion by Herpes Simplex Virus Type 1 Glycoproteins C and E Lauren M. Hook, Jialing Huang, Ming Jiang, Richard Hodinka, and Harvey M. Friedman J. Virol. July 2008 82: 6935-6941; published ahead of print May 14, 2008, doi:10.1128/JVI.02599-07 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Aberrant Lymphocyte Activation Precedes Delayed Virus-Specific T-Cell Response after both Primary Infection and Secondary Exposure to Hepadnavirus in the Woodchuck Model of Hepatitis B Virus Infection Shashi A. Gujar, Adam K. Jenkins, Clifford S. Guy, Jinguo Wang, and Tomasz I. Michalak J. Virol. July 2008 82: 6992-7008; published ahead of print May 14, 2008, doi:10.1128/JVI.00661-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Immune Response to Herpes Simplex Virus Type 1 Infection in Susceptible Mice Is a Major Cause of Central Nervous System Pathology Resulting in Fatal Encephalitis Patric Lundberg, Chandran Ramakrishna, Jeffrey Brown, J. Michael Tyszka, Mark Hamamura, David R. Hinton, Susan Kovats, Orhan Nalcioglu, Kenneth Weinberg, Harry Openshaw, and Edouard M. Cantin J. Virol. July 2008 82: 7078-7088; published ahead of print May 14, 2008, doi:10.1128/JVI.00619-08 [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

R5X4 Viruses Are Evolutionary, Functional, and Antigenic Intermediates in the Pathway of a Simian-Human Immunodeficiency Virus Coreceptor Switch Silvana Tasca, Siu-Hong Ho, and Cecilia Cheng-Mayer J. Virol. July 2008 82: 7089-7099; published ahead of print May 14, 2008, doi:10.1128/JVI.00570-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

An Extremely Diverse CD4 Response to Vaccinia Virus in Humans Is Revealed by Proteome-Wide T-Cell Profiling Lichen Jing, D. Huw Davies, Tiana M. Chong, Sookhee Chun, Christopher L. McClurkan, Jay Huang, Brian T. Story, Douglas M. Molina, Siddiqua Hirst, Philip L. Felgner, and David M. Koelle J. Virol. July 2008 82: 7120-7134; published ahead of print May 14, 2008, doi:10.1128/JVI.00453-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Enhanced Mucosal Immunoglobulin A Response and Solid Protection against Foot-and-Mouth Disease Virus Challenge Induced by a Novel Dendrimeric Peptide Carolina Cubillos, Beatriz G. de la Torre, Annamaria Jakab, Giorgia Clementi, Eva Borrás, Juan Bárcena, David Andreu, Francisco Sobrino, and Esther Blanco J. Virol. July 2008 82: 7223-7230; published ahead of print April 30, 2008, doi:10.1128/JVI.00401-08 [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

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Vaccines and Antiviral Agents:

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Differential Antigen Requirements for Protection against Systemic and Intranasal Vaccinia Virus Challenges in Mice David R. Kaufman, Jaap Goudsmit, Lennart Holterman, Bonnie A. Ewald, Matthew Denholtz, Colleen Devoy, Ayush Giri, Lauren E. Grandpre, Jean-Michel Heraud, Genoveffa Franchini, Michael S. Seaman, Menzo J. E. Havenga, and Dan H. Barouch J. Virol. July 2008 82: 6829-6837; published ahead of print April 30, 2008, doi:10.1128/JVI.00353-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Tetravalent Dengue Vaccine Based on a Complex Adenovirus Vector Provides Significant Protection in Rhesus Monkeys against All Four Serotypes of Dengue Virus Kanakatte Raviprakash, Danher Wang, Dan Ewing, David H. Holman, Karla Block, Jan Woraratanadharm, Lan Chen, Curtis Hayes, John Y. Dong, and Kevin Porter J. Virol. July 2008 82: 6927-6934; published ahead of print May 14, 2008, doi:10.1128/JVI.02724-07 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Humanized Monoclonal Antibodies Derived from Chimpanzee Fabs Protect against Japanese Encephalitis Virus In Vitro and In Vivo Ana P. Goncalvez, Cheng-Hsin Chien, Kamolchanok Tubthong, Inna Gorshkova, Carrie Roll, Olivia Donau, Peter Schuck, Sutee Yoksan, Sy-Dar Wang, Robert H. Purcell, and Ching-Juh Lai J. Virol. July 2008 82: 7009-7021; published ahead of print May 14, 2008, doi:10.1128/JVI.00291-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Genome Replication and Regulation of Viral Gene Expression:

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Reverse Transcriptase- and RNA Packaging Signal-Dependent Incorporation of APOBEC3G into Hepatitis B Virus Nucleocapsids David H. Nguyen and Jianming Hu J. Virol. July 2008 82: 6852-6861; published ahead of print May 14, 2008, doi:10.1128/JVI.00465-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synthesis of Genomic and Subgenomic RNA in Mosquito Cells Infected with Two Sindbis Virus nsP4 Mutants: Influence of Intracellular Nucleoside Triphosphate Concentrations Mei-Ling Li, Tzu-Yu Kwan, H. Anne Simmonds, and Victor Stollar J. Virol. July 2008 82: 6880-6888; published ahead of print May 28, 2008, doi:10.1128/JVI.00517-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of Initiating Nucleoside Triphosphate Concentrations in the Regulation of Influenza Virus Replication and Transcription Frank T. Vreede, Hugh Gifford, and George G. Brownlee J. Virol. July 2008 82: 6902-6910; published ahead of print May 7, 2008, doi:10.1128/JVI.00627-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cdc34p Ubiquitin-Conjugating Enzyme Is a Component of the Tombusvirus Replicase Complex and Ubiquitinates p33 Replication Protein Zhenghe Li, Daniel Barajas, Tadas Panavas, David A. Herbst, and Peter D. Nagy J. Virol. July 2008 82: 6911-6926; published ahead of print May 7, 2008, doi:10.1128/JVI.00702-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of Mutated Cyclization Sequences That Permit Efficient Replication of West Nile Virus Genomes: Use in Safer Propagation of a Novel Vaccine Candidate Ryosuke Suzuki, Rafik Fayzulin, Ilya Frolov, and Peter W. Mason J. Virol. July 2008 82: 6942-6951; published ahead of print May 14, 2008, doi:10.1128/JVI.00662-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Interactions among the West Nile Virus Methyltransferase, the RNA-Dependent RNA Polymerase, and the 5' Stem-Loop of Genomic RNA Bo Zhang, Hongping Dong, Yangsheng Zhou, and Pei-Yong Shi J. Virol. July 2008 82: 7047-7058; published ahead of print April 30, 2008, doi:10.1128/JVI.00654-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Development of Cell Lines That Provide Tightly Controlled Temporal Translation of the Human Cytomegalovirus IE2 Proteins for Complementation and Functional Analyses of Growth-Impaired and Nonviable IE2 Mutant Viruses Rebecca L. Sanders, Charles L. Clark, Christopher S. Morello, and Deborah H. Spector J. Virol. July 2008 82: 7059-7077; published ahead of print May 7, 2008, doi:10.1128/JVI.00675-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Cytoplasmic Terminus of Kaposi's Sarcoma-Associated Herpesvirus Glycoprotein B Is Not Essential for Virion Egress and Infectivity R. Subramanian, O. D'Auvergne, Haixia Kong, and K. G. Kousoulas J. Virol. July 2008 82: 7144-7154; published ahead of print May 14, 2008, doi:10.1128/JVI.00617-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

CDK13, a New Potential Human Immunodeficiency Virus Type 1 Inhibitory Factor Regulating Viral mRNA Splicing Reem Berro, Caitlin Pedati, Kylene Kehn-Hall, Weilin Wu, Zachary Klase, Yasmine Even, Anne-Marie Genevière, Tatiana Ammosova, Sergei Nekhai, and Fatah Kashanchi J. Virol. July 2008 82: 7155-7166; published ahead of print May 14, 2008, doi:10.1128/JVI.02543-07 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Severe Acute Respiratory Syndrome Coronavirus Protein 6 Accelerates Murine Hepatitis Virus Infections by More than One Mechanism Snawar Hussain, Stanley Perlman, and Thomas M. Gallagher J. Virol. July 2008 82: 7212-7222; published ahead of print April 30, 2008, doi:10.1128/JVI.02406-07 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Extreme Dependence of gH and gL Expression on ORF57 and Association with Highly Unusual Codon Usage in Rhesus Monkey Rhadinovirus John P. Bilello, Jennifer S. Morgan, and Ronald C. Desrosiers J. Virol. July 2008 82: 7231-7237; published ahead of print May 14, 2008, doi:10.1128/JVI.00564-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Virus-Cell Interactions:

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Identification of the Myelin Protein Plasmolipin as the Cell Entry Receptor for Mus caroli Endogenous Retrovirus A. Dusty Miller, Ulla Bergholz, Marion Ziegler, and Carol Stocking J. Virol. July 2008 82: 6862-6868; published ahead of print May 7, 2008, doi:10.1128/JVI.00397-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human T-Cell Leukemia Virus Type 1 Tax Attenuates the ATM-Mediated Cellular DNA Damage Response Chandtip Chandhasin, Razvan I. Ducu, Elijahu Berkovich, Michael B. Kastan, and Susan J. Marriott J. Virol. July 2008 82: 6952-6961; published ahead of print April 23, 2008, doi:10.1128/JVI.02331-07 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Nucleocapsid Protein of Severe Acute Respiratory Syndrome Coronavirus Inhibits Cell Cytokinesis and Proliferation by Interacting with Translation Elongation Factor 1 Bing Zhou, Junli Liu, Qiuna Wang, Xuan Liu, Xiaorong Li, Ping Li, Qingjun Ma, and Cheng Cao J. Virol. July 2008 82: 6962-6971; published ahead of print April 30, 2008, doi:10.1128/JVI.00133-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Five-Amino-Acid Deletion of the Eastern Equine Encephalitis Virus Capsid Protein Attenuates Replication in Mammalian Systems but Not in Mosquito Cells Patricia V. Aguilar, Lawrence W. Leung, Eryu Wang, Scott C. Weaver, and Christopher F. Basler J. Virol. July 2008 82: 6972-6983; published ahead of print May 14, 2008, doi:10.1128/JVI.01283-07 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Monitoring Early Fusion Dynamics of Human Immunodeficiency Virus Type 1 at Single-Molecule Resolution Terrence M. Dobrowsky, Yan Zhou, Sean X. Sun, Robert F. Siliciano, and Denis Wirtz J. Virol. July 2008 82: 7022-7033; published ahead of print May 14, 2008, doi:10.1128/JVI.00053-08 [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Intersubunit Disulfide Isomerization Controls Membrane Fusion of Human T-Cell Leukemia Virus Env Kejun Li, Shujing Zhang, Malin Kronqvist, Michael Wallin, Maria Ekström, David Derse, and Henrik Garoff J. Virol. July 2008 82: 7135-7143; published ahead of print May 14, 2008, doi:10.1128/JVI.00448-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of the New World Monkey Homologues of Human Poliovirus Receptor CD155 Shaukat Khan, Xiaozhong Peng, Jiang Yin, Ping Zhang, and Eckard Wimmer J. Virol. July 2008 82: 7167-7179; published ahead of print May 14, 2008, doi:10.1128/JVI.02664-07 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Epstein-Barr Virus SM Protein Functions as an Alternative Splicing Factor Dinesh Verma and Sankar Swaminathan J. Virol. July 2008 82: 7180-7188; published ahead of print May 7, 2008, doi:10.1128/JVI.00344-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Infection with Vpr-Positive Human Immunodeficiency Virus Type 1 Impairs NK Cell Function Indirectly through Cytokine Dysregulation of Infected Target Cells Biswanath Majumder, Narasimhan J. Venkatachari, Shaylee O'Leary, and Velpandi Ayyavoo J. Virol. July 2008 82: 7189-7200; published ahead of print April 16, 2008, doi:10.1128/JVI.01979-07 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cell Adhesion Promotes Ebola Virus Envelope Glycoprotein-Mediated Binding and Infection Derek Dube, Kathryn L. Schornberg, Tzanko S. Stantchev, Matthew I. Bonaparte, Sue E. Delos, Amy H. Bouton, Christopher C. Broder, and Judith M. White J. Virol. July 2008 82: 7238-7242; published ahead of print April 30, 2008, doi:10.1128/JVI.00425-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Gene Delivery:

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Genotypic Features of Lentivirus Transgenic Mice Marc-Olivier Sauvain, Alexander P. Dorr, Brian Stevenson, Alexandra Quazzola, Félix Naef, Maciej Wiznerowicz, Frédéric Schütz, Victor Jongeneel, Denis Duboule, François Spitz, and Didier Trono J. Virol. July 2008 82: 7111-7119; published ahead of print May 7, 2008, doi:10.1128/JVI.00623-08 [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

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Genetic Diversity and Evolution:

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Rhesus Macaque TRIM5 Alleles Have Divergent Antiretroviral Specificities Sam J. Wilson, Benjamin L. J. Webb, Charlotte Maplanka, Ruchi M. Newman, Ernst J. Verschoor, Jonathan L. Heeney, and Greg J. Towers J. Virol. July 2008 82: 7243-7247; published ahead of print May 14, 2008, doi:10.1128/JVI.00307-08 [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Author's Correction:

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IRF-3 Activation by Sendai Virus Infection Is Required for Cellular Apoptosis and Avoidance of Persistence Kristi Peters, Saurabh Chattopadhyay, and Ganes C. Sen J. Virol. July 2008 82: 7248 [Full Text] [PDF] [Reprints and Permissions]

Mutational Evidence of Internal Fusion Loops in Herpes Simplex Virus Glycoprotein B Brian P. Hannah, Ekaterina E. Heldwein, Florent C. Bender, Gary H. Cohen, and Roselyn J. Eisenberg J. Virol. July 2008 82: 7249 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.