Cover photograph (Copyright © 2007, American Society for Microbiology. All Rights Reserved.): The hepatitis B virus subviral envelope particle formed by its major surface protein self-assembles into filaments in the lumen of the endoplasmic reticulum (ER). These long filaments are then packed into crystal-like structures, which are transported by ER-derived vesicles to the ER-Golgi intermediate compartment, where they are unpacked and relaxed. This electron micrograph shows purified, negatively strained filaments. (See related article on page 3842.)
[Table of Contents]