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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2007 81: 2543-2544. [Full Text] [PDF] FREE [Reprints and Permissions]  

Pathogenesis and Immunity:

Henry Radziewicz, Chris C. Ibegbu, Marina L. Fernandez, Kimberly A. Workowski, Kamil Obideen, Mohammad Wehbi, Holly L. Hanson, James P. Steinberg, David Masopust, E. John Wherry, John D. Altman, Barry T. Rouse, Gordon J. Freeman, Rafi Ahmed, and Arash Grakoui

Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression
J. Virol. 2007 81: 2545-2553. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ye Ye, Kevin Hauns, Jeffrey O. Langland, Bertram L. Jacobs, and Brenda G. Hogue

Mouse Hepatitis Coronavirus A59 Nucleocapsid Protein Is a Type I Interferon Antagonist
J. Virol. 2007 81: 2554-2563. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Melanie A. Samuel, John D. Morrey, and Michael S. Diamond

Caspase 3-Dependent Cell Death of Neurons Contributes to the Pathogenesis of West Nile Virus Encephalitis
J. Virol. 2007 81: 2614-2623. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John T. Loffredo, Benjamin J. Burwitz, Eva G. Rakasz, Sean P. Spencer, Jason J. Stephany, Juan Pablo Giraldo Vela, Sarah R. Martin, Jason Reed, Shari M. Piaskowski, Jessica Furlott, Kim L. Weisgrau, Denise S. Rodrigues, Taeko Soma, Gnankang Napoé, Thomas C. Friedrich, Nancy A. Wilson, Esper G. Kallas, and David I. Watkins

The Antiviral Efficacy of Simian Immunodeficiency Virus-Specific CD8⁺ T Cells Is Unrelated to Epitope Specificity and Is Abrogated by Viral Escape
J. Virol. 2007 81: 2624-2634. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brent L. Williams, Kavitha Yaddanapudi, Mady Hornig, and W. Ian Lipkin

Spatiotemporal Analysis of Purkinje Cell Degeneration Relative to Parasagittal Expression Domains in a Model of Neonatal Viral Infection
J. Virol. 2007 81: 2675-2687. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Santhi Gorantla, Hannah Sneller, Lisa Walters, John G. Sharp, Samuel J. Pirruccello, John T. West, Charles Wood, Stephen Dewhurst, Howard E. Gendelman, and Larisa Poluektova

Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2^–/–_c^–/– Mice
J. Virol. 2007 81: 2700-2712. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John C. Tilton, Marlise R. Luskin, Alison J. Johnson, Maura Manion, Claire W. Hallahan, Julia A. Metcalf, Mary McLaughlin, Richard T. Davey, Jr., and Mark Connors

Changes in Paracrine Interleukin-2 Requirement, CCR7 Expression, Frequency, and Cytokine Secretion of Human Immunodeficiency Virus-Specific CD4⁺ T Cells Are a Consequence of Antigen Load
J. Virol. 2007 81: 2713-2725. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kristy J. Szretter, Shivaprakash Gangappa, Xuihua Lu, Chalanda Smith, Wun-Ju Shieh, Sherif R. Zaki, Suryaprakash Sambhara, Terrence M. Tumpey, and Jacqueline M. Katz

Role of Host Cytokine Responses in the Pathogenesis of Avian H5N1 Influenza Viruses in Mice
J. Virol. 2007 81: 2736-2744. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rob J. De Boer

Understanding the Failure of CD8⁺ T-Cell Vaccination against Simian/Human Immunodeficiency Virus
J. Virol. 2007 81: 2838-2848. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dai-Wei Liu, Yuh-Cheng Yang, Ho-Fan Lin, Mei-Fang Lin, Ya-Wen Cheng, Chen-Chung Chu, Yeou-Ping Tsao, and Show-Li Chen

Cytotoxic T-Lymphocyte Responses to Human Papillomavirus Type 16 E5 and E7 Proteins and HLA-A*0201-Restricted T-Cell Peptides in Cervical Cancer Patients
J. Virol. 2007 81: 2869-2879. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kelly L. McCann and Farhad Imani

Transforming Growth Factor ß Enhances Respiratory Syncytial Virus Replication and Tumor Necrosis Factor Alpha Induction in Human Epithelial Cells
J. Virol. 2007 81: 2880-2886. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sandra M. Mueller, Birgit Schaetz, Kathrin Eismann, Silke Bergmann, Michael Bauerle, Matthias Schmitt-Haendle, Hauke Walter, Barbara Schmidt, Klaus Korn, Heinrich Sticht, Bernd Spriewald, Ellen G. Harrer, and Thomas Harrer

Dual Selection Pressure by Drugs and HLA Class I-Restricted Immune Responses on Human Immunodeficiency Virus Type 1 Protease
J. Virol. 2007 81: 2887-2898. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Adam J. Gehring, Dianxing Sun, Patrick T. F. Kennedy, Esther Nolte-'t Hoen, Seng Gee Lim, Shanthi Wasser, Clare Selden, Mala K. Maini, Dan M. Davis, Michael Nassal, and Antonio Bertoletti

The Level of Viral Antigen Presented by Hepatocytes Influences CD8 T-Cell Function
J. Virol. 2007 81: 2940-2949. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Randall J. Cohrs and Donald H. Gilden

Prevalence and Abundance of Latently Transcribed Varicella-Zoster Virus Genes in Human Ganglia
J. Virol. 2007 81: 2950-2956. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ryan D. Estep, Michael F. Powers, Bonnie K. Yen, He Li, and Scott W. Wong

Construction of an Infectious Rhesus Rhadinovirus Bacterial Artificial Chromosome for the Analysis of Kaposi's Sarcoma-Associated Herpesvirus-Related Disease Development
J. Virol. 2007 81: 2957-2969. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jane E. Libbey, Ikuo Tsunoda, J. Lindsay Whitton, and Robert S. Fujinami

Infectious RNA Isolated from the Spinal Cords of Mice Chronically Infected with Theiler's Murine Encephalomyelitis Virus
J. Virol. 2007 81: 3009-3011. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Virus-Cell Interactions:

Maino Tahara, Makoto Takeda, Fumio Seki, Takao Hashiguchi, and Yusuke Yanagi

Multiple Amino Acid Substitutions in Hemagglutinin Are Necessary for Wild-Type Measles Virus To Acquire the Ability To Use Receptor CD46 Efficiently
J. Virol. 2007 81: 2564-2572. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Matloob Husain, Andrea S. Weisberg, and Bernard Moss

Sequence-Independent Targeting of Transmembrane Proteins Synthesized within Vaccinia Virus Factories to Nascent Viral Membranes
J. Virol. 2007 81: 2646-2655. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eric M. Norstrom, Mark F. Ciaccio, Benjamin Rassbach, Robert Wollmann, and James A. Mastrianni

Cytosolic Prion Protein Toxicity Is Independent of Cellular Prion Protein Expression and Prion Propagation
J. Virol. 2007 81: 2831-2837. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Xue-Lin Bian, Germán Rosas-Acosta, Yu-Chieh Wu, and Van G. Wilson

Nuclear Import of Bovine Papillomavirus Type 1 E1 Protein Is Mediated by Multiple Alpha Importins and Is Negatively Regulated by Phosphorylation near a Nuclear Localization Signal
J. Virol. 2007 81: 2899-2908. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

José Rivera, Charles Abrams, Bruno Hernáez, Alberto Alcázar, José M. Escribano, Linda Dixon, and Covadonga Alonso

The MyD116 African Swine Fever Virus Homologue Interacts with the Catalytic Subunit of Protein Phosphatase 1 and Activates Its Phosphatase Activity
J. Virol. 2007 81: 2923-2929. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gabriele Neumann, Thomas W. Geisbert, Hideki Ebihara, Joan B. Geisbert, Kathleen M. Daddario-DiCaprio, Heinz Feldmann, and Yoshihiro Kawaoka

Proteolytic Processing of the Ebola Virus Glycoprotein Is Not Critical for Ebola Virus Replication in Nonhuman Primates
J. Virol. 2007 81: 2995-2998. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karine Labadie, Aure Saulnier, Sandra Martin-Latil, and Florence Colbère-Garapin

Reduced Apoptosis in Human Intestinal Cells Cured of Persistent Poliovirus Infection
J. Virol. 2007 81: 3033-3036. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Genome Replication and Regulation of Viral Gene Expression:

Elizabeth A. White, Christia J. Del Rosario, Rebecca L. Sanders, and Deborah H. Spector

The IE2 60-Kilodalton and 40-Kilodalton Proteins Are Dispensable for Human Cytomegalovirus Replication but Are Required for Efficient Delayed Early and Late Gene Expression and Production of Infectious Virus
J. Virol. 2007 81: 2573-2583. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Keisuke Komoda, Natsuki Mawatari, Yuka Hagiwara-Komoda, Satoshi Naito, and Masayuki Ishikawa

Identification of a Ribonucleoprotein Intermediate of Tomato Mosaic Virus RNA Replication Complex Formation
J. Virol. 2007 81: 2584-2591. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Richard A. Katz, Emily Jack-Scott, Anna Narezkina, Ivan Palagin, Pamela Boimel, Joseph Kulkosky, Emmanuelle Nicolas, James G. Greger, and Anna Marie Skalka

High-Frequency Epigenetic Repression and Silencing of Retroviruses Can Be Antagonized by Histone Deacetylase Inhibitors and Transcriptional Activators, but Uniform Reactivation in Cell Clones Is Restricted by Additional Mechanisms
J. Virol. 2007 81: 2592-2604. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chaoyang Ye and David J. Pintel

Upstream AP1- and CREB-Binding Sites Confer High Basal Activity on the Adeno-Associated Virus Type 5 Capsid Gene Promoter
J. Virol. 2007 81: 2605-2613. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Victor V. Keasler, Amanda J. Hodgson, Charles R. Madden, and Betty L. Slagle

Enhancement of Hepatitis B Virus Replication by the Regulatory X Protein In Vitro and In Vivo
J. Virol. 2007 81: 2656-2662. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Volker Brass, Zsuzsanna Pal, Nicolas Sapay, Gilbert Deléage, Hubert E. Blum, François Penin, and Darius Moradpour

Conserved Determinants for Membrane Association of Nonstructural Protein 5A from Hepatitis C Virus and Related Viruses
J. Virol. 2007 81: 2745-2757. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Giuseppe Balistreri, Javier Caldentey, Leevi Kääriäinen, and Tero Ahola

Enzymatic Defects of the nsP2 Proteins of Semliki Forest Virus Temperature-Sensitive Mutants
J. Virol. 2007 81: 2849-2860. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael Topper, Yang Luo, Maria Zhadina, Kevin Mohammed, Leonard Smith, and Mark A. Muesing

Posttranslational Acetylation of the Human Immunodeficiency Virus Type 1 Integrase Carboxyl-Terminal Domain Is Dispensable for Viral Replication
J. Virol. 2007 81: 3012-3017. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Y. W. Huang, T. Opriessnig, P. G. Halbur, and X. J. Meng

Initiation at the Third In-Frame AUG Codon of Open Reading Frame 3 of the Hepatitis E Virus Is Essential for Viral Infectivity In Vivo
J. Virol. 2007 81: 3018-3026. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chad Myskiw, Yvon Deschambault, Kristel Jefferies, Runtao He, and Jingxin Cao

Aurintricarboxylic Acid Inhibits the Early Stage of Vaccinia Virus Replication by Targeting both Cellular and Viral Factors
J. Virol. 2007 81: 3027-3032. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Genetic Diversity and Evolution:

K. M. Xu, K. S. Li, G. J. D. Smith, J. W. Li, H. Tai, J. X. Zhang, R. G. Webster, J. S. M. Peiris, H. Chen, and Y. Guan

Evolution and Molecular Epidemiology of H9N2 Influenza A Viruses from Quail in Southern China, 2000 to 2005
J. Virol. 2007 81: 2635-2645. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brian H. Bird, Marina L. Khristova, Pierre E. Rollin, Thomas G. Ksiazek, and Stuart T. Nichol

Complete Genome Analysis of 33 Ecologically and Biologically Diverse Rift Valley Fever Virus Strains Reveals Widespread Virus Movement and Low Genetic Diversity due to Recent Common Ancestry
J. Virol. 2007 81: 2805-2816. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. J. Bull, R. Sanjuán, and C. O. Wilke

Theory of Lethal Mutagenesis for Viruses
J. Virol. 2007 81: 2930-2939. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Jessica J. Hayward, John Taylor, and Allen G. Rodrigo

Phylogenetic Analysis of Feline Immunodeficiency Virus in Feral and Companion Domestic Cats of New Zealand
J. Virol. 2007 81: 2999-3004. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Transformation and Oncogenesis:

Maria I. Garcia, Joseph Kaserman, Young-Hwa Chung, Jae U. Jung, and Sun-Hwa Lee

Herpesvirus Saimiri STP-A Oncoprotein Utilizes Src Family Protein Tyrosine Kinase and Tumor Necrosis Factor Receptor-Associated Factors To Elicit Cellular Signal Transduction
J. Virol. 2007 81: 2663-2674. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Daniel F. Gaddy and Douglas S. Lyles

Oncolytic Vesicular Stomatitis Virus Induces Apoptosis via Signaling through PKR, Fas, and Daxx
J. Virol. 2007 81: 2792-2804. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Zsolt Fábián, Christine M. Csatary, József Szeberényi, and Laszlo K. Csatary

p53-Independent Endoplasmic Reticulum Stress-Mediated Cytotoxicity of a Newcastle Disease Virus Strain in Tumor Cell Lines
J. Virol. 2007 81: 2817-2830. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gene Delivery:

Andrea Hesse, Daniela Kosmides, Roland E. Kontermann, and Dirk M. Nettelbeck

Tropism Modification of Adenovirus Vectors by Peptide Ligand Insertion into Various Positions of the Adenovirus Serotype 41 Short-Fiber Knob Domain
J. Virol. 2007 81: 2688-2699. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Structure and Assembly:

Joel D. Baines, Chyong-Ere Hsieh, Elizabeth Wills, Carmen Mannella, and Michael Marko

Electron Tomography of Nascent Herpes Simplex Virus Virions
J. Virol. 2007 81: 2726-2735. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Geneviève Mottet-Osman, Frédéric Iseni, Thierry Pelet, Maciej Wiznerowicz, Dominique Garcin, and Laurent Roux

Suppression of the Sendai Virus M Protein through a Novel Short Interfering RNA Approach Inhibits Viral Particle Production but Does Not Affect Viral RNA Synthesis
J. Virol. 2007 81: 2861-2868. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fadila Bouamr, Brian R. Houck-Loomis, Martha De Los Santos, Rebecca J. Casaday, Marc C. Johnson, and Stephen P. Goff

The C-Terminal Portion of the Hrs Protein Interacts with Tsg101 and Interferes with Human Immunodeficiency Virus Type 1 Gag Particle Production
J. Virol. 2007 81: 2909-2922. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nelli J. Karhu, Gabija Ziedaite, Dennis H. Bamford, and Jaana K. H. Bamford

Efficient DNA Packaging of Bacteriophage PRD1 Requires the Unique Vertex Protein P6
J. Virol. 2007 81: 2970-2979. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christopher Buser, Paul Walther, Thomas Mertens, and Detlef Michel

Cytomegalovirus Primary Envelopment Occurs at Large Infoldings of the Inner Nuclear Membrane
J. Virol. 2007 81: 3042-3048. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cellular Response to Infection:

Iyadh Douagi, Gerald M. McInerney, Åsa S. Hidmark, Vassoula Miriallis, Kari Johansen, Lennart Svensson, and Gunilla B. Karlsson Hedestam

Role of Interferon Regulatory Factor 3 in Type I Interferon Responses in Rotavirus-Infected Dendritic Cells and Fibroblasts
J. Virol. 2007 81: 2758-2768. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christina F. Spiropoulou, César G. Albariño, Thomas G. Ksiazek, and Pierre E. Rollin

Andes and Prospect Hill Hantaviruses Differ in Early Induction of Interferon although Both Can Downregulate Interferon Signaling
J. Virol. 2007 81: 2769-2776. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Giorgio Mangino, Zulema A. Percario, Gianna Fiorucci, Gabriele Vaccari, Santiago Manrique, Giovanna Romeo, Maurizio Federico, Matthias Geyer, and Elisabetta Affabris

In Vitro Treatment of Human Monocytes/Macrophages with Myristoylated Recombinant Nef of Human Immunodeficiency Virus Type 1 Leads to the Activation of Mitogen-Activated Protein Kinases, IB Kinases, and Interferon Regulatory Factor 3 and to the Release of Beta Interferon
J. Virol. 2007 81: 2777-2791. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Asuka Itaya, Xuehua Zhong, Ralf Bundschuh, Yijun Qi, Ying Wang, Ryuta Takeda, Ann R. Harris, Carlos Molina, Richard S. Nelson, and Biao Ding

A Structured Viroid RNA Serves as a Substrate for Dicer-Like Cleavage To Produce Biologically Active Small RNAs but Is Resistant to RNA-Induced Silencing Complex-Mediated Degradation
J. Virol. 2007 81: 2980-2994. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vaccines and Antiviral Agents:

David L. Wyles, Kelly A. Kaihara, Florin Vaida, and Robert T. Schooley

Synergy of Small Molecular Inhibitors of Hepatitis C Virus Replication Directed at Multiple Viral Targets
J. Virol. 2007 81: 3005-3008. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mian-er Cong, Walid Heneine, and J. Gerardo García-Lerma

The Fitness Cost of Mutations Associated with Human Immunodeficiency Virus Type 1 Drug Resistance Is Modulated by Mutational Interactions
J. Virol. 2007 81: 3037-3041. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.