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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2007 81: 1053. [Full Text] [PDF] FREE  

Minireviews:

Jeremy Luban

Cyclophilin A, TRIM5, and Resistance to Human Immunodeficiency Virus Type 1 Infection
J. Virol. 2007 81: 1054-1061. [Full Text] [PDF]  

Genome Replication and Regulation of Viral Gene Expression:

Vladimir Majerciak, Natalia Pripuzova, J. Philip McCoy, Shou-Jiang Gao, and Zhi-Ming Zheng

Targeted Disruption of Kaposi's Sarcoma-Associated Herpesvirus ORF57 in the Viral Genome Is Detrimental for the Expression of ORF59, K8, and K8.1 and the Production of Infectious Virus
J. Virol. 2007 81: 1062-1071. [Abstract] [Full Text] [PDF]  

Yoshihiro Izumiya, Chie Izumiya, Albert Van Geelen, Don-Hong Wang, Kit S. Lam, Paul A. Luciw, and Hsing-Jien Kung

Kaposi's Sarcoma-Associated Herpesvirus-Encoded Protein Kinase and Its Interaction with K-bZIP
J. Virol. 2007 81: 1072-1082. [Abstract] [Full Text] [PDF]  

Chih-Chung Lu, Ho-Ting Huang, Jiin-Tarng Wang, Geir Slupphaug, Tsai-Kun Li, Meng-Chuan Wu, Yi-Chun Chen, Chung-Pei Lee, and Mei-Ru Chen

Characterization of the Uracil-DNA Glycosylase Activity of Epstein-Barr Virus BKRF3 and Its Role in Lytic Viral DNA Replication
J. Virol. 2007 81: 1195-1208. [Abstract] [Full Text] [PDF]  

Scott J. Goebel, Timothy B. Miller, Corey J. Bennett, Kristen A. Bernard, and Paul S. Masters

A Hypervariable Region within the 3' cis-Acting Element of the Murine Coronavirus Genome Is Nonessential for RNA Synthesis but Affects Pathogenesis
J. Virol. 2007 81: 1274-1287. [Abstract] [Full Text] [PDF]  

Jared L. Spidel, Carol B. Wilson, Rebecca C. Craven, and John W. Wills

Genetic Studies of the ß-Hairpin Loop of Rous Sarcoma Virus Capsid Protein
J. Virol. 2007 81: 1288-1296. [Abstract] [Full Text] [PDF]  

Humayra Ali, Gary LeRoy, Gemma Bridge, and S. J. Flint

The Adenovirus L4 33-Kilodalton Protein Binds to Intragenic Sequences of the Major Late Promoter Required for Late Phase-Specific Stimulation of Transcription
J. Virol. 2007 81: 1327-1338. [Abstract] [Full Text] [PDF]  

Hiroyuki Mizumoto, Yuji Tomaru, Yoshitake Takao, Yoko Shirai, and Keizo Nagasaki

Intraspecies Host Specificity of a Single-Stranded RNA Virus Infecting a Marine Photosynthetic Protist Is Determined at the Early Steps of Infection
J. Virol. 2007 81: 1372-1378. [Abstract] [Full Text] [PDF]  

Yoshifumi Iwamaru, Takato Takenouchi, Kazumasa Ogihara, Megumi Hoshino, Masuhiro Takata, Morikazu Imamura, Yuichi Tagawa, Hiroko Hayashi-Kato, Yuko Ushiki-Kaku, Yoshihisa Shimizu, Hiroyuki Okada, Morikazu Shinagawa, Hiroshi Kitani, and Takashi Yokoyama

Microglial Cell Line Established from Prion Protein-Overexpressing Mice Is Susceptible to Various Murine Prion Strains
J. Virol. 2007 81: 1524-1527. [Abstract] [Full Text] [PDF]  

Vaccines and Antiviral Agents:

Ioanna Skountzou, Fu-Shi Quan, Sailaja Gangadhara, Ling Ye, Andrei Vzorov, Periasamy Selvaraj, Joshy Jacob, Richard W. Compans, and Sang-Moo Kang

Incorporation of Glycosylphosphatidylinositol-Anchored Granulocyte- Macrophage Colony-Stimulating Factor or CD40 Ligand Enhances Immunogenicity of Chimeric Simian Immunodeficiency Virus-Like Particles
J. Virol. 2007 81: 1083-1094. [Abstract] [Full Text] [PDF]  

Denis Leclerc, Diane Beauseigle, Jérome Denis, Hélène Morin, Christine Paré, Alain Lamarre, and Réjean Lapointe

Proteasome-Independent Major Histocompatibility Complex Class I Cross-Presentation Mediated by Papaya Mosaic Virus-Like Particles Leads to Expansion of Specific Human T Cells
J. Virol. 2007 81: 1319-1326. [Abstract] [Full Text] [PDF]  

Virus-Cell Interactions:

Yujuan Yue, Amitinder Kaur, Meghan K. Eberhardt, Nadine Kassis, Shan Shan Zhou, Alice F. Tarantal, and Peter A. Barry

Immunogenicity and Protective Efficacy of DNA Vaccines Expressing Rhesus Cytomegalovirus Glycoprotein B, Phosphoprotein 65-2, and Viral Interleukin-10 in Rhesus Macaques
J. Virol. 2007 81: 1095-1109. [Abstract] [Full Text] [PDF]  

Katy Moffat, Caroline Knox, Gareth Howell, Sarah J. Clark, H. Yang, Graham J. Belsham, Martin Ryan, and Thomas Wileman

Inhibition of the Secretory Pathway by Foot-and-Mouth Disease Virus 2BC Protein Is Reproduced by Coexpression of 2B with 2C, and the Site of Inhibition Is Determined by the Subcellular Location of 2C
J. Virol. 2007 81: 1129-1139. [Abstract] [Full Text] [PDF]  

Z. Orynbayeva, S. Kolusheva, N. Groysman, N. Gavrielov, L. Lobel, and R. Jelinek

Vaccinia Virus Interactions with the Cell Membrane Studied by New Chromatic Vesicle and Cell Sensor Assays
J. Virol. 2007 81: 1140-1147. [Abstract] [Full Text] [PDF]  

Masayuki Shirakura, Kyoko Murakami, Tohru Ichimura, Ryosuke Suzuki, Tetsu Shimoji, Kouichirou Fukuda, Katsutoshi Abe, Shigeko Sato, Masayoshi Fukasawa, Yoshio Yamakawa, Masahiro Nishijima, Kohji Moriishi, Yoshiharu Matsuura, Takaji Wakita, Tetsuro Suzuki, Peter M. Howley, Tatsuo Miyamura, and Ikuo Shoji

E6AP Ubiquitin Ligase Mediates Ubiquitylation and Degradation of Hepatitis C Virus Core Protein
J. Virol. 2007 81: 1174-1185. [Abstract] [Full Text] [PDF]  

J. Kelley Bentley, Dawn C. Newcomb, Adam M. Goldsmith, Yue Jia, Uma S. Sajjan, and Marc B. Hershenson

Rhinovirus Activates Interleukin-8 Expression via a Src/p110ß Phosphatidylinositol 3-Kinase/Akt Pathway in Human Airway Epithelial Cells
J. Virol. 2007 81: 1186-1194. [Abstract] [Full Text] [PDF]  

Chandra Tangudu, Heidi Olivares, Jason Netland, Stanley Perlman, and Thomas Gallagher

Severe Acute Respiratory Syndrome Coronavirus Protein 6 Accelerates Murine Coronavirus Infections
J. Virol. 2007 81: 1220-1229. [Abstract] [Full Text] [PDF]  

Sonia M. Tusell, Stephanie A. Schittone, and Kathryn V. Holmes

Mutational Analysis of Aminopeptidase N, a Receptor for Several Group 1 Coronaviruses, Identifies Key Determinants of Viral Host Range
J. Virol. 2007 81: 1261-1273. [Abstract] [Full Text] [PDF]  

Alexis H. Broquet, Christelle Lenoir, Agnès Gardet, Catherine Sapin, Serge Chwetzoff, Anne-Marie Jouniaux, Susana Lopez, Germain Trugnan, Maria Bachelet, and Ginette Thomas

Hsp70 Negatively Controls Rotavirus Protein Bioavailability in Caco-2 Cells Infected by the Rotavirus RF Strain
J. Virol. 2007 81: 1297-1304. [Abstract] [Full Text] [PDF]  

Tadasuke Naito, Fumitaka Momose, Atsushi Kawaguchi, and Kyosuke Nagata

Involvement of Hsp90 in Assembly and Nuclear Import of Influenza Virus RNA Polymerase Subunits
J. Virol. 2007 81: 1339-1349. [Abstract] [Full Text] [PDF]  

Mark W. Hansberger, Jacquelyn A. Campbell, Pranav Danthi, Pia Arrate, Kevin N. Pennington, Kenneth B. Marcu, Dean W. Ballard, and Terence S. Dermody

IB Kinase Subunits and Are Required for Activation of NF-B and Induction of Apoptosis by Mammalian Reovirus
J. Virol. 2007 81: 1360-1371. [Abstract] [Full Text] [PDF]  

Ping Liu, Mohammad Jamaluddin, Kui Li, Roberto P. Garofalo, Antonella Casola, and Allan R. Brasier

Retinoic Acid-Inducible Gene I Mediates Early Antiviral Response and Toll-Like Receptor 3 Expression in Respiratory Syncytial Virus-Infected Airway Epithelial Cells
J. Virol. 2007 81: 1401-1411. [Abstract] [Full Text] [PDF]  

Wang-Jing Liu, Yun-Shiang Chang, Andrew H.-J. Wang, Guang-Hsiung Kou, and Chu-Fang Lo

White Spot Syndrome Virus Annexes a Shrimp STAT To Enhance Expression of the Immediate-Early Gene ie1
J. Virol. 2007 81: 1461-1471. [Abstract] [Full Text] [PDF]  

Norihiro Takenouchi, Kathryn S. Jones, Ivonne Lisinski, Kazunori Fugo, Karen Yao, Samuel W. Cushman, Francis W. Ruscetti, and Steven Jacobson

GLUT1 Is Not the Primary Binding Receptor but Is Associated with Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1
J. Virol. 2007 81: 1506-1510. [Abstract] [Full Text] [PDF]  

Cesar Muñoz-Fontela, Laura Marcos-Villar, Pedro Gallego, Javier Arroyo, Marco Da Costa, Karen M. Pomeranz, Eric W.-F. Lam, and Carmen Rivas

Latent Protein LANA2 from Kaposi's Sarcoma-Associated Herpesvirus Interacts with 14-3-3 Proteins and Inhibits FOXO3a Transcription Factor
J. Virol. 2007 81: 1511-1516. [Abstract] [Full Text] [PDF]  

Pathogenesis and Immunity:

Anirban Roy, Timothy W. Phares, Hilary Koprowski, and D. Craig Hooper

Failure To Open the Blood-Brain Barrier and Deliver Immune Effectors to Central Nervous System Tissues Leads to the Lethal Outcome of Silver-Haired Bat Rabies Virus Infection
J. Virol. 2007 81: 1110-1118. [Abstract] [Full Text] [PDF]  

Chien-Te K. Tseng, Cheng Huang, Patrick Newman, Nan Wang, Krishna Narayanan, Douglas M. Watts, Shinji Makino, Michelle M. Packard, Sherif R. Zaki, Teh-sheng Chan, and Clarence J. Peters

Severe Acute Respiratory Syndrome Coronavirus Infection of Mice Transgenic for the Human Angiotensin-Converting Enzyme 2 Virus Receptor
J. Virol. 2007 81: 1162-1173. [Abstract] [Full Text] [PDF]  

Kirsten L. Hokeness, Elizabeth S. Deweerd, Michael W. Munks, Casey A. Lewis, Ronald P. Gladue, and Thais P. Salazar-Mather

CXCR3-Dependent Recruitment of Antigen-Specific T Lymphocytes to the Liver during Murine Cytomegalovirus Infection
J. Virol. 2007 81: 1241-1250. [Abstract] [Full Text] [PDF]  

Devin B. Lowe, Michael H. Shearer, Cynthia A. Jumper, Robert K. Bright, and Ronald C. Kennedy

Fc Receptors Play a Dominant Role in Protective Tumor Immunity against a Virus-Encoded Tumor-Specific Antigen in a Murine Model of Experimental Pulmonary Metastases
J. Virol. 2007 81: 1313-1318. [Abstract] [Full Text] [PDF]  

Rong Rong, Frederic Bibollet-Ruche, Joseph Mulenga, Susan Allen, Jerry L. Blackwell, and Cynthia A. Derdeyn

Role of V1V2 and Other Human Immunodeficiency Virus Type 1 Envelope Domains in Resistance to Autologous Neutralization during Clade C Infection
J. Virol. 2007 81: 1350-1359. [Abstract] [Full Text] [PDF]  

Andre Ortlieb Guerreiro-Cacais, Mehmet Uzunel, Jelena Levitskaya, and Victor Levitsky

Inhibition of Heavy Chain and ß₂-Microglobulin Synthesis as a Mechanism of Major Histocompatibility Complex Class I Downregulation during Epstein-Barr Virus Replication
J. Virol. 2007 81: 1390-1400. [Abstract] [Full Text] [PDF]  

Mayumi Nakagawa, Kevin H. Kim, Tiffany M. Gillam, and Anna-Barbara Moscicki

HLA Class I Binding Promiscuity of the CD8 T-Cell Epitopes of Human Papillomavirus Type 16 E6 Protein
J. Virol. 2007 81: 1412-1423. [Abstract] [Full Text] [PDF]  

W. J. Honnen, C. Krachmarov, S. C. Kayman, M. K. Gorny, S. Zolla-Pazner, and A. Pinter

Type-Specific Epitopes Targeted by Monoclonal Antibodies with Exceptionally Potent Neutralizing Activities for Selected Strains of Human Immunodeficiency Virus Type 1 Map to a Common Region of the V2 Domain of gp120 and Differ Only at Single Positions from the Clade B Consensus Sequence
J. Virol. 2007 81: 1424-1432. [Abstract] [Full Text] [PDF]  

Jae-Ouk Kim, Bimal K. Chakrabarti, Anuradha Guha-Niyogi, Mark K. Louder, John R. Mascola, Lakshmanan Ganesh, and Gary J. Nabel

Lysis of Human Immunodeficiency Virus Type 1 by a Specific Secreted Human Phospholipase A₂
J. Virol. 2007 81: 1444-1450. [Abstract] [Full Text] [PDF]  

Patric Lundberg, Paula V. Welander, Carl K. Edwards, III, Nico van Rooijen, and Edouard Cantin

Tumor Necrosis Factor (TNF) Protects Resistant C57BL/6 Mice against Herpes Simplex Virus-Induced Encephalitis Independently of Signaling via TNF Receptor 1 or 2
J. Virol. 2007 81: 1451-1460. [Abstract] [Full Text] [PDF]  

Guido Wollmann, Michael D. Robek, and Anthony N. van den Pol

Variable Deficiencies in the Interferon Response Enhance Susceptibility to Vesicular Stomatitis Virus Oncolytic Actions in Glioblastoma Cells but Not in Normal Human Glial Cells
J. Virol. 2007 81: 1479-1491. [Abstract] [Full Text] [PDF]  

Edward Acheampong, Zahida Parveen, Aschalew Mengistu, Noel Ngoubilly, Brian Wigdahl, Albert S. Lossinsky, Roger J. Pomerantz, and Muhammad Mukhtar

Cholesterol-Depleting Statin Drugs Protect Postmitotically Differentiated Human Neurons against Ethanol- and Human Immunodeficiency Virus Type 1-Induced Oxidative Stress In Vitro
J. Virol. 2007 81: 1492-1501. [Abstract] [Full Text] [PDF]  

Christophe Butticaz, Olivier Michielin, Josiane Wyniger, Amalio Telenti, and Sylvia Rothenberger

Silencing of both ß-TrCP1 and HOS (ß-TrCP2) Is Required To Suppress Human Immunodeficiency Virus Type 1 Vpu-Mediated CD4 Down-Modulation
J. Virol. 2007 81: 1502-1505. [Abstract] [Full Text] [PDF]  

Chungwon Chung, Wonhee Lee, John T. Loffredo, Benjamin Burwitz, Thomas C. Friedrich, Juan Pablo Giraldo Vela, Gnankang Napoe, Eva G. Rakasz, Nancy A. Wilson, David B. Allison, and David I. Watkins

Not All Cytokine-Producing CD8⁺ T Cells Suppress Simian Immunodeficiency Virus Replication
J. Virol. 2007 81: 1517-1523. [Abstract] [Full Text] [PDF]  

Mingli Qi and Christopher Aiken

Selective Restriction of Nef-Defective Human Immunodeficiency Virus Type 1 by a Proteasome-Dependent Mechanism
J. Virol. 2007 81: 1534-1536. [Abstract] [Full Text] [PDF]  

Structure and Assembly:

Shantanu Kumar, Wendy Ochoa, Shinichi Kobayashi, and Vijay S. Reddy

Presence of a Surface-Exposed Loop Facilitates Trypsinization of Particles of Sinsiro Virus, a Genogroup II.3 Norovirus
J. Virol. 2007 81: 1119-1128. [Abstract] [Full Text] [PDF]  

G. Sullivan Read and Mary Patterson

Packaging of the Virion Host Shutoff (Vhs) Protein of Herpes Simplex Virus: Two Forms of the Vhs Polypeptide Are Associated with Intranuclear B and C Capsids, but Only One Is Associated with Enveloped Virions
J. Virol. 2007 81: 1148-1161. [Abstract] [Full Text] [PDF]  

Xiangzhi Meng, Addie Embry, Debbi Sochia, and Yan Xiang

Vaccinia Virus A6L Encodes a Virion Core Protein Required for Formation of Mature Virion
J. Virol. 2007 81: 1433-1443. [Abstract] [Full Text] [PDF]  

Ayna Alfadhli, Doug Huseby, Eliot Kapit, Dalbinder Colman, and Eric Barklis

Human Immunodeficiency Virus Type 1 Matrix Protein Assembles on Membranes as a Hexamer
J. Virol. 2007 81: 1472-1478. [Abstract] [Full Text] [PDF]  

Takaichi Hamano, Kazuhiro Matsuo, Yurina Hibi, Ann Florence B. Victoriano, Naoko Takahashi, Yosio Mabuchi, Tsuyoshi Soji, Shinji Irie, Pathom Sawanpanyalert, Hideki Yanai, Takashi Hara, Shudo Yamazaki, Naoki Yamamoto, and Takashi Okamoto

A Single-Nucleotide Synonymous Mutation in the gag Gene Controlling Human Immunodeficiency Virus Type 1 Virion Production
J. Virol. 2007 81: 1528-1533. [Abstract] [Full Text] [PDF]  

Cellular Response to Infection:

Andrea J. Pruijssers and Michael R. Strand

PTP-H2 and PTP-H3 from Microplitis demolitor Bracovirus Localize to Focal Adhesions and Are Antiphagocytic in Insect Immune Cells
J. Virol. 2007 81: 1209-1219. [Abstract] [Full Text] [PDF]  

Carisa A. Zampieri, Jean-Francois Fortin, Garry P. Nolan, and Gary J. Nabel

The ERK Mitogen-Activated Protein Kinase Pathway Contributes to Ebola Virus Glycoprotein-Induced Cytotoxicity
J. Virol. 2007 81: 1230-1240. [Abstract] [Full Text] [PDF]  

Milena Iacobelli-Martinez and Glen R. Nemerow

Preferential Activation of Toll-Like Receptor Nine by CD46-Utilizing Adenoviruses
J. Virol. 2007 81: 1305-1312. [Abstract] [Full Text] [PDF]  

Gene Delivery:

Marianne M. Stanford, John W. Barrett, Steven H. Nazarian, Steven Werden, and Grant McFadden

Oncolytic Virotherapy Synergism with Signaling Inhibitors: Rapamycin Increases Myxoma Virus Tropism for Human Tumor Cells
J. Virol. 2007 81: 1251-1260. [Abstract] [Full Text] [PDF]  

Transformation and Oncogenesis:

Keisuke Handa, Takashi Yugawa, Mako Narisawa-Saito, Shin-ichi Ohno, Masatoshi Fujita, and Tohru Kiyono

E6AP-Dependent Degradation of DLG4/PSD95 by High-Risk Human Papillomavirus Type 18 E6 Protein
J. Virol. 2007 81: 1379-1389. [Abstract] [Full Text] [PDF]  

Errata:

Homer D. Pantua, Lori W. McGinnes, Mark E. Peeples, and Trudy G. Morrison

Requirements for the Assembly and Release of Newcastle Disease Virus-Like Particles
J. Virol. 2007 81: 1537. [Full Text] [PDF]  

Nina R. Derby, Zane Kraft, Elaine Kan, Emma T. Crooks, Susan W. Barnett, Indresh K. Srivastava, James M. Binley, and Leonidas Stamatatos

Antibody Responses Elicited in Macaques Immunized with Human Immunodeficiency Virus Type 1 (HIV-1) SF162-Derived gp140 Envelope Immunogens: Comparison with Those Elicited during Homologous Simian/Human Immunodeficiency Virus SHIV_SF162P4 and Heterologous HIV-1 Infection
J. Virol. 2007 81: 1538. [Full Text] [PDF]  

Dina Alzhanova and Dennis E. Hruby

A trans-Golgi Network Resident Protein, golgin-97, Accumulates in Viral Factories and Incorporates into Virions during Poxvirus Infection
J. Virol. 2007 81: 1539. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.