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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2007 81: 6775-6776. [Full Text] [PDF] FREE  

Minireviews:

Jan D. Lünemann, Thomas Kamradt, Roland Martin, and Christian Münz

Epstein-Barr Virus: Environmental Trigger of Multiple Sclerosis?
J. Virol. 2007 81: 6777-6784. [Full Text] [PDF]  

Pathogenesis and Immunity:

Christopher T. Cornell, William B. Kiosses, Stephanie Harkins, and J. Lindsay Whitton

Coxsackievirus B3 Proteins Directionally Complement Each Other To Downregulate Surface Major Histocompatibility Complex Class I
J. Virol. 2007 81: 6785-6797. [Abstract] [Full Text] [PDF]  

Kening Wang, Gowtham Mahalingam, Susan E. Hoover, Erik K. Mont, Steven M. Holland, Jeffrey I. Cohen, and Stephen E. Straus

Diverse Herpes Simplex Virus Type 1 Thymidine Kinase Mutants in Individual Human Neurons and Ganglia
J. Virol. 2007 81: 6817-6826. [Abstract] [Full Text] [PDF]  

Hui-Ling Yen, Aleksandr S. Lipatov, Natalia A. Ilyushina, Elena A. Govorkova, John Franks, Neziha Yilmaz, Alan Douglas, Alan Hay, Scott Krauss, Jerold E. Rehg, Erich Hoffmann, and Robert G. Webster

Inefficient Transmission of H5N1 Influenza Viruses in a Ferret Contact Model
J. Virol. 2007 81: 6890-6898. [Abstract] [Full Text] [PDF]  

Anna Ekman, Kati Hokynar, Laura Kakkola, Kalle Kantola, Lea Hedman, Heidi Bondén, Matthias Gessner, Claudia Aberham, Päivi Norja, Simo Miettinen, Klaus Hedman, and Maria Söderlund-Venermo

Biological and Immunological Relations among Human Parvovirus B19 Genotypes 1 to 3
J. Virol. 2007 81: 6927-6935. [Abstract] [Full Text] [PDF]  

Zilin Nie, Gary D. Bren, Stacey R. Vlahakis, Alicia Algeciras Schimnich, Jason M. Brenchley, Sergey A. Trushin, Sarah Warren, David J. Schnepple, Colin M. Kovacs, Mona R. Loutfy, Daniel C. Douek, and Andrew D. Badley

Human Immunodeficiency Virus Type 1 Protease Cleaves Procaspase 8 In Vivo
J. Virol. 2007 81: 6947-6956. [Abstract] [Full Text] [PDF]  

Li-Wu Qian, Jianping Xie, Fengchun Ye, and Shou-Jiang Gao

Kaposi's Sarcoma-Associated Herpesvirus Infection Promotes Invasion of Primary Human Umbilical Vein Endothelial Cells by Inducing Matrix Metalloproteinases
J. Virol. 2007 81: 7001-7010. [Abstract] [Full Text] [PDF]  

Milosz Faber, Marie-Luise Faber, Jianwei Li, Mirjam A. R. Preuss, Matthias J. Schnell, and Bernhard Dietzschold

Dominance of a Nonpathogenic Glycoprotein Gene over a Pathogenic Glycoprotein Gene in Rabies Virus
J. Virol. 2007 81: 7041-7047. [Abstract] [Full Text] [PDF]  

Mauro Pires Moraes, Teresa de los Santos, Marla Koster, Traci Turecek, He Wang, Vladimir G. Andreyev, and Marvin J. Grubman

Enhanced Antiviral Activity against Foot-and-Mouth Disease Virus by a Combination of Type I and II Porcine Interferons
J. Virol. 2007 81: 7124-7135. [Abstract] [Full Text] [PDF]  

Ina Frank, Claudia Budde, Melanie Fiedler, Uta Dahmen, Sergei Viazov, Mengji Lu, Ulf Dittmer, and Michael Roggendorf

Acute Resolving Woodchuck Hepatitis Virus (WHV) Infection Is Associated with a Strong Cytotoxic T-Lymphocyte Response to a Single WHV Core Peptide
J. Virol. 2007 81: 7156-7163. [Abstract] [Full Text] [PDF]  

Jiafen Hu, Xuwen Peng, Lynn R. Budgeon, Nancy M. Cladel, Karla K. Balogh, and Neil D. Christensen

Establishment of a Cottontail Rabbit Papillomavirus/HLA-A2.1 Transgenic Rabbit Model
J. Virol. 2007 81: 7171-7177. [Abstract] [Full Text] [PDF]  

Jessica K. Roth-Cross, Luis Martínez-Sobrido, Erin P. Scott, Adolfo García-Sastre, and Susan R. Weiss

Inhibition of the Alpha/Beta Interferon Response by Mouse Hepatitis Virus at Multiple Levels
J. Virol. 2007 81: 7189-7199. [Abstract] [Full Text] [PDF]  

Purnima Bhat and David A. Anderson

Hepatitis B Virus Translocates across a Trophoblastic Barrier
J. Virol. 2007 81: 7200-7207. [Abstract] [Full Text] [PDF]  

Akito Sakai, Shingo Takikawa, Robert Thimme, Jean-Christophe Meunier, Hans Christian Spangenberg, Sugantha Govindarajan, Patrizia Farci, Suzanne U. Emerson, Francis V. Chisari, Robert H. Purcell, and Jens Bukh

In Vivo Study of the HC-TN Strain of Hepatitis C Virus Recovered from a Patient with Fulminant Hepatitis: RNA Transcripts of a Molecular Clone (pHC-TN) Are Infectious in Chimpanzees but Not in Huh7.5 Cells
J. Virol. 2007 81: 7208-7219. [Abstract] [Full Text] [PDF]  

Thierry Baron and Anne-Gaëlle Biacabe

Molecular Behaviors of "CH1641-Like" Sheep Scrapie Isolates in Ovine Transgenic Mice (TgOvPrP4)
J. Virol. 2007 81: 7230-7237. [Abstract] [Full Text] [PDF]  

Dennis M. Walling, Autumn J. Ray, Joan E. Nichols, Catherine M. Flaitz, and C. Mark Nichols

Epstein-Barr Virus Infection of Langerhans Cell Precursors as a Mechanism of Oral Epithelial Entry, Persistence, and Reactivation
J. Virol. 2007 81: 7249-7268. [Abstract] [Full Text] [PDF]  

Rebekah M. Brennan, John J. Miles, Sharon L. Silins, Melissa J. Bell, Jacqueline M. Burrows, and Scott R. Burrows

Predictable ß T-Cell Receptor Selection toward an HLA-B*3501-Restricted Human Cytomegalovirus Epitope
J. Virol. 2007 81: 7269-7273. [Abstract] [Full Text] [PDF]  

Samantha L. Finstad, Naomi Rosenberg, and Laura S. Levy

Diminished Potential for B-Lymphoid Differentiation after Murine Leukemia Virus Infection In Vivo and in EML Hematopoietic Progenitor Cells
J. Virol. 2007 81: 7274-7279. [Abstract] [Full Text] [PDF]  

Gabriele Vaccari, Claudia D'Agostino, Romolo Nonno, Francesca Rosone, Michela Conte, Michele Angelo Di Bari, Barbara Chiappini, Elena Esposito, Luigi De Grossi, Francesco Giordani, Stefano Marcon, Luisella Morelli, Renata Borroni, and Umberto Agrimi

Prion Protein Alleles Showing a Protective Effect on the Susceptibility of Sheep to Scrapie and Bovine Spongiform Encephalopathy
J. Virol. 2007 81: 7306-7309. [Abstract] [Full Text] [PDF]  

Structure and Assembly:

Tomoichiro Oka, Mami Yamamoto, Masaru Yokoyama, Satoko Ogawa, Grant S. Hansman, Kazuhiko Katayama, Kana Miyashita, Hirotaka Takagi, Yukinobu Tohya, Hironori Sato, and Naokazu Takeda

Highly Conserved Configuration of Catalytic Amino Acid Residues among Calicivirus-Encoded Proteases
J. Virol. 2007 81: 6798-6806. [Abstract] [Full Text] [PDF]  

Klaartje Houben, Dominique Marion, Nicolas Tarbouriech, Rob W. H. Ruigrok, and Laurence Blanchard

Interaction of the C-Terminal Domains of Sendai Virus N and P Proteins: Comparison of Polymerase-Nucleocapsid Interactions within the Paramyxovirus Family
J. Virol. 2007 81: 6807-6816. [Abstract] [Full Text] [PDF]  

Daniel Luque, Irene Saugar, José F. Rodríguez, Nuria Verdaguer, Damiá Garriga, Carmen San Martín, Javier A. Velázquez-Muriel, Benes L. Trus, José L. Carrascosa, and José R. Castón

Infectious Bursal Disease Virus Capsid Assembly and Maturation by Structural Rearrangements of a Transient Molecular Switch
J. Virol. 2007 81: 6869-6878. [Abstract] [Full Text] [PDF]  

Liza S. Z. Larsen, Min Zhang, Nadejda Beliakova-Bethell, Virginia Bilanchone, Anne Lamsa, Kunio Nagashima, Rani Najdi, Kathryn Kosaka, Vuk Kovacevic, Jianlin Cheng, Pierre Baldi, G. Wesley Hatfield, and Suzanne Sandmeyer

Ty3 Capsid Mutations Reveal Early and Late Functions of the Amino-Terminal Domain
J. Virol. 2007 81: 6957-6972. [Abstract] [Full Text] [PDF]  

Benjamin J. Chen, George P. Leser, Eiji Morita, and Robert A. Lamb

Influenza Virus Hemagglutinin and Neuraminidase, but Not the Matrix Protein, Are Required for Assembly and Budding of Plasmid-Derived Virus-Like Particles
J. Virol. 2007 81: 7111-7123. [Abstract] [Full Text] [PDF]  

Juan A. Mondotte, Pierre-Yves Lozach, Ali Amara, and Andrea V. Gamarnik

Essential Role of Dengue Virus Envelope Protein N Glycosylation at Asparagine-67 during Viral Propagation
J. Virol. 2007 81: 7136-7148. [Abstract] [Full Text] [PDF]  

Kady M. Honeychurch, Guang Yang, Robert Jordan, and Dennis E. Hruby

The Vaccinia Virus F13L YPPL Motif Is Required for Efficient Release of Extracellular Enveloped Virus
J. Virol. 2007 81: 7310-7315. [Abstract] [Full Text] [PDF]  

Virus-Cell Interactions:

Maino Tahara, Makoto Takeda, and Yusuke Yanagi

Altered Interaction of the Matrix Protein with the Cytoplasmic Tail of Hemagglutinin Modulates Measles Virus Growth by Affecting Virus Assembly and Cell-Cell Fusion
J. Virol. 2007 81: 6827-6836. [Abstract] [Full Text] [PDF]  

B. Feierbach, M. Bisher, J. Goodhouse, and L. W. Enquist

In Vitro Analysis of Transneuronal Spread of an Alphaherpesvirus Infection in Peripheral Nervous System Neurons
J. Virol. 2007 81: 6846-6857. [Abstract] [Full Text] [PDF] [Supplemental material]  

Kelly M. Fahrbach, Sheila M. Barry, Seyoum Ayehunie, Sarah Lamore, Mitchell Klausner, and Thomas J. Hope

Activated CD34-Derived Langerhans Cells Mediate Transinfection with Human Immunodeficiency Virus
J. Virol. 2007 81: 6858-6868. [Abstract] [Full Text] [PDF]  

Carmen Yea, Joanna Dembowy, Laura Pacione, and Martha Brown

Microtubule-Mediated and Microtubule-Independent Transport of Adenovirus Type 5 in HEK293 Cells
J. Virol. 2007 81: 6899-6908. [Abstract] [Full Text] [PDF]  

Gregory S. Park, Keely L. Morris, Roselyn G. Hallett, Marshall E. Bloom, and Sonja M. Best

Identification of Residues Critical for the Interferon Antagonist Function of Langat Virus NS5 Reveals a Role for the RNA-Dependent RNA Polymerase Domain
J. Virol. 2007 81: 6936-6946. [Abstract] [Full Text] [PDF]  

Carsten Münk, Jörg Zielonka, Hannelore Constabel, Björn-Philipp Kloke, Benjamin Rengstl, Marion Battenberg, Francesca Bonci, Mauro Pistello, Martin Löchelt, and Klaus Cichutek

Multiple Restrictions of Human Immunodeficiency Virus Type 1 in Feline Cells
J. Virol. 2007 81: 7048-7060. [Abstract] [Full Text] [PDF]  

Dana Westphal, Elizabeth C. Ledgerwood, Merilyn H. Hibma, Stephen B. Fleming, Ellena M. Whelan, and Andrew A. Mercer

A Novel Bcl-2-Like Inhibitor of Apoptosis Is Encoded by the Parapoxvirus Orf Virus
J. Virol. 2007 81: 7178-7188. [Abstract] [Full Text] [PDF]  

Jacob S. Yount, Thomas M. Moran, and Carolina B. López

Cytokine-Independent Upregulation of MDA5 in Viral Infection
J. Virol. 2007 81: 7316-7319. [Abstract] [Full Text] [PDF]  

Genome Replication and Regulation of Viral Gene Expression:

Krista A. Delviks-Frankenberry, Galina N. Nikolenko, Rebekah Barr, and Vinay K. Pathak

Mutations in Human Immunodeficiency Virus Type 1 RNase H Primer Grip Enhance 3'-Azido-3'-Deoxythymidine Resistance
J. Virol. 2007 81: 6837-6845. [Abstract] [Full Text] [PDF]  

Jianming Qiu, Fang Cheng, and David Pintel

The Abundant R2 mRNA Generated by Aleutian Mink Disease Parvovirus Is Tricistronic, Encoding NS2, VP1, and VP2
J. Virol. 2007 81: 6993-7000. [Abstract] [Full Text] [PDF]  

Amy Baker, Kent J. Rohleder, Les A. Hanakahi, and Gary Ketner

Adenovirus E4 34k and E1b 55k Oncoproteins Target Host DNA Ligase IV for Proteasomal Degradation
J. Virol. 2007 81: 7034-7040. [Abstract] [Full Text] [PDF]  

Miguel A. Sanz, Alfredo Castelló, and Luis Carrasco

Viral Translation Is Coupled to Transcription in Sindbis Virus-Infected Cells
J. Virol. 2007 81: 7061-7068. [Abstract] [Full Text] [PDF]  

Kelly S. Colletti, Kate E. Smallenburg, Yiyang Xu, and Gregory S. Pari

Human Cytomegalovirus UL84 Interacts with an RNA Stem-Loop Sequence Found within the RNA/DNA Hybrid Region of oriLyt
J. Virol. 2007 81: 7077-7085. [Abstract] [Full Text] [PDF]  

Eric F. Donaldson, Rachel L. Graham, Amy C. Sims, Mark R. Denison, and Ralph S. Baric

Analysis of Murine Hepatitis Virus Strain A59 Temperature-Sensitive Mutant TS-LA6 Suggests that nsp10 Plays a Critical Role in Polyprotein Processing
J. Virol. 2007 81: 7086-7098. [Abstract] [Full Text] [PDF]  

Jean L. Mbisa, Rebekah Barr, James A. Thomas, Nick Vandegraaff, Irene J. Dorweiler, Evguenia S. Svarovskaia, William L. Brown, Louis M. Mansky, Robert J. Gorelick, Reuben S. Harris, Alan Engelman, and Vinay K. Pathak

Human Immunodeficiency Virus Type 1 cDNAs Produced in the Presence of APOBEC3G Exhibit Defects in Plus-Strand DNA Transfer and Integration
J. Virol. 2007 81: 7099-7110. [Abstract] [Full Text] [PDF] [Supplemental material]  

Celine Schelcher, Salama Al Mehairi, Elizabeth Verrall, Questa Hope, Kirsty Flower, Beth Bromley, Derek N. Woolfson, Michelle J. West, and Alison J. Sinclair

Atypical bZIP Domain of Viral Transcription Factor Contributes to Stability of Dimer Formation and Transcriptional Function
J. Virol. 2007 81: 7149-7155. [Abstract] [Full Text] [PDF]  

Yongxiu Yao, Yuguang Zhao, Hongtao Xu, Lorraine P. Smith, Charles H. Lawrie, Alain Sewer, Mihaela Zavolan, and Venugopal Nair

Marek's Disease Virus Type 2 (MDV-2)-Encoded MicroRNAs Show No Sequence Conservation with Those Encoded by MDV-1
J. Virol. 2007 81: 7164-7170. [Abstract] [Full Text] [PDF]  

Kun Luo, Tao Wang, Bindong Liu, Chunjuan Tian, Zuoxiang Xiao, John Kappes, and Xiao-Fang Yu

Cytidine Deaminases APOBEC3G and APOBEC3F Interact with Human Immunodeficiency Virus Type 1 Integrase and Inhibit Proviral DNA Formation
J. Virol. 2007 81: 7238-7248. [Abstract] [Full Text] [PDF]  

Haihan Song, Emi E. Nakayama, Masaru Yokoyama, Hironori Sato, Jay A. Levy, and Tatsuo Shioda

A Single Amino Acid of the Human Immunodeficiency Virus Type 2 Capsid Affects Its Replication in the Presence of Cynomolgus Monkey and Human TRIM5s
J. Virol. 2007 81: 7280-7285. [Abstract] [Full Text] [PDF]  

Marion Poenisch, Sandra Wille, Andreas Ackermann, Peter Staeheli, and Urs Schneider

The X Protein of Borna Disease Virus Serves Essential Functions in the Viral Multiplication Cycle
J. Virol. 2007 81: 7297-7299. [Abstract] [Full Text] [PDF]  

Heiko Adler, Beatrix Steer, Klaus Freimüller, and Jürgen Haas

Murine Gammaherpesvirus 68 Contains Two Functional Lytic Origins of Replication
J. Virol. 2007 81: 7300-7305. [Abstract] [Full Text] [PDF]  

Vaccines and Antiviral Agents:

Mathieu Boxus, Marylène Tignon, Stefan Roels, Jean-François Toussaint, Karl Walravens, Marie-Ange Benoit, Philippe Coppe, Jean-Jacques Letesson, Carine Letellier, and Pierre Kerkhofs

DNA Immunization with Plasmids Encoding Fusion and Nucleocapsid Proteins of Bovine Respiratory Syncytial Virus Induces a Strong Cell-Mediated Immunity and Protects Calves against Challenge
J. Virol. 2007 81: 6879-6889. [Abstract] [Full Text] [PDF]  

Frederik Pauwels, Wendy Mostmans, Ludo M. M. Quirynen, Liesbet van der Helm, Carlo W. Boutton, Anne-Stéphanie Rueff, Erna Cleiren, Pierre Raboisson, Dominique Surleraux, Origène Nyanguile, and Kenneth A. Simmen

Binding-Site Identification and Genotypic Profiling of Hepatitis C Virus Polymerase Inhibitors
J. Virol. 2007 81: 6909-6919. [Abstract] [Full Text] [PDF]  

J. David Beckham, Robin J. Goody, Penny Clarke, Christophe Bonny, and Kenneth L. Tyler

Novel Strategy for Treatment of Viral Central Nervous System Infection by Using a Cell-Permeating Inhibitor of c-Jun N-Terminal Kinase
J. Virol. 2007 81: 6984-6992. [Abstract] [Full Text] [PDF]  

Xiugen Zhang, Farah Cassis-Ghavami, Mike Eller, Jeff Currier, Bonnie M. Slike, Xuemin Chen, James Tartaglia, Mary Marovich, and Paul Spearman

Direct Comparison of Antigen Production and Induction of Apoptosis by Canarypox Virus- and Modified Vaccinia Virus Ankara-Human Immunodeficiency Virus Vaccine Vectors
J. Virol. 2007 81: 7022-7033. [Abstract] [Full Text] [PDF]  

Genetic Diversity and Evolution:

B. Q. Dong, W. Liu, X. H. Fan, D. Vijaykrishna, X. C. Tang, F. Gao, L. F. Li, G. J. Li, J. X. Zhang, L. Q. Yang, L. L. M. Poon, S. Y. Zhang, J. S. M. Peiris, G. J. D. Smith, H. Chen, and Y. Guan

Detection of a Novel and Highly Divergent Coronavirus from Asian Leopard Cats and Chinese Ferret Badgers in Southern China
J. Virol. 2007 81: 6920-6926. [Abstract] [Full Text] [PDF]  

Gene Delivery:

Matthias Paar, Sonja Schwab, Doris Rosenfellner, Brian Salmons, Walter H. Günzburg, Matthias Renner, and Daniel Portsmouth

Effects of Viral Strain, Transgene Position, and Target Cell Type on Replication Kinetics, Genomic Stability, and Transgene Expression of Replication-Competent Murine Leukemia Virus-Based Vectors
J. Virol. 2007 81: 6973-6983. [Abstract] [Full Text] [PDF]  

Urs Schneider, Andreas Ackermann, and Peter Staeheli

A Borna Disease Virus Vector for Expression of Foreign Genes in Neurons of Rodents
J. Virol. 2007 81: 7293-7296. [Abstract] [Full Text] [PDF]  

Cellular Response to Infection:

Georg Kochs, Adolfo García-Sastre, and Luis Martínez-Sobrido

Multiple Anti-Interferon Actions of the Influenza A Virus NS1 Protein
J. Virol. 2007 81: 7011-7021. [Abstract] [Full Text] [PDF]  

Peter Berglund, Diana Finzi, Jack R. Bennink, and Jonathan W. Yewdell

Viral Alteration of Cellular Translational Machinery Increases Defective Ribosomal Products
J. Virol. 2007 81: 7220-7229. [Abstract] [Full Text] [PDF]  

Winson S. C. Ho and Anthony N. van den Pol

Bystander Attenuation of Neuronal and Astrocyte Intercellular Communication by Murine Cytomegalovirus Infection of Glia
J. Virol. 2007 81: 7286-7292. [Abstract] [Full Text] [PDF]  

Transformation and Oncogenesis:

Tamara Utermark, Brian S. Schaffhausen, Thomas M. Roberts, and Jean J. Zhao

The p110 Isoform of Phosphatidylinositol 3-Kinase Is Essential for Polyomavirus Middle T Antigen-Mediated Transformation
J. Virol. 2007 81: 7069-7076. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

S. Pignatelli, P. Dal Monte, M. P. Landini, B. Severi, R. Nassiri, J. Gilloteaux, J. M. Papadimitriou, G. R. Shellam, Thomas Mertens, Christopher Buser, Detlef Michel, and Paul Walther

Cytomegalovirus Primary Envelopment at Large Nuclear Membrane Infoldings: What's New?
J. Virol. 2007 81: 7320-7322. [Full Text] [PDF]  

Author's Correction:

Zhao Han, Elessa Marendy, Yong-Dong Wang, Jing Yuan, Jeffery T. Sample, and Sankar Swaminathan

Multiple Roles of Epstein-Barr Virus SM Protein in Lytic Replication
J. Virol. 2007 81: 7323. [Full Text] [PDF]  

Eduardo Mortola, Rob Noad, and Polly Roy

Bluetongue Virus Outer Capsid Proteins Are Sufficient To Trigger Apoptosis in Mammalian Cells
J. Virol. 2007 81: 7324. [Full Text] [PDF]  

Rob J. De Boer

Understanding the Failure of CD8⁺ T-Cell Vaccination against Simian/Human Immunodeficiency Virus
J. Virol. 2007 81: 7325. [Full Text] [PDF]  

Min Hua Luo, Kyle Rosenke, Kamila Czornak, and Elizabeth A. Fortunato

Human Cytomegalovirus Disrupts both Ataxia Telangiectasia Mutated Protein (ATM)- and ATM-Rad3-Related Kinase-Mediated DNA Damage Responses during Lytic Infection
J. Virol. 2007 81: 7326. [Full Text] [PDF]  

Torsten Schaller, Nicole Appel, George Koutsoudakis, Stephanie Kallis, Volker Lohmann, Thomas Pietschmann, and Ralf Bartenschlager

Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes
J. Virol. 2007 81: 7327. [Full Text] [PDF]  

Tina M. Cairns, Lisa S. Friedman, Huan Lou, J. Charles Whitbeck, Marie S. Shaner, Gary H. Cohen, and Roselyn J. Eisenberg

N-Terminal Mutants of Herpes Simplex Virus Type 2 gH Are Transported without gL but Require gL for Function
J. Virol. 2007 81: 7328. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.