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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2007 81: 6163. [Full Text] [PDF] FREE  

Genome Replication and Regulation of Viral Gene Expression:

Weifan Gao and Jianming Hu

Formation of Hepatitis B Virus Covalently Closed Circular DNA: Removal of Genome-Linked Protein
J. Virol. 2007 81: 6164-6174. [Abstract] [Full Text] [PDF]  

Hiroki Isomura, Mark F. Stinski, Ayumi Kudoh, Sanae Nakayama, Satoko Iwahori, Yoshitaka Sato, and Tatsuya Tsurumi

The Late Promoter of the Human Cytomegalovirus Viral DNA Polymerase Processivity Factor Has an Impact on Delayed Early and Late Viral Gene Products but Not on Viral DNA Synthesis
J. Virol. 2007 81: 6197-6206. [Abstract] [Full Text] [PDF]  

Eric B. Lewellyn and Daniel D. Loeb

Base Pairing between cis-Acting Sequences Contributes to Template Switching during Plus-Strand DNA Synthesis in Human Hepatitis B Virus
J. Virol. 2007 81: 6207-6215. [Abstract] [Full Text] [PDF]  

Sébastien Alain Chevalier, Marine Walic, Sara Calattini, Adeline Mallet, Marie-Christine Prévost, Antoine Gessain, and Renaud Mahieux

Construction and Characterization of a Full-Length Infectious Simian T-Cell Lymphotropic Virus Type 3 Molecular Clone
J. Virol. 2007 81: 6276-6285. [Abstract] [Full Text] [PDF]  

Zhilong Yang and Charles Wood

The Transcriptional Repressor K-RBP Modulates RTA-Mediated Transactivation and Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus
J. Virol. 2007 81: 6294-6306. [Abstract] [Full Text] [PDF]  

Eric F. Donaldson, Amy C. Sims, Rachel L. Graham, Mark R. Denison, and Ralph S. Baric

Murine Hepatitis Virus Replicase Protein nsp10 Is a Critical Regulator of Viral RNA Synthesis
J. Virol. 2007 81: 6356-6368. [Abstract] [Full Text] [PDF]  

Daniel M. Strauss and Deborah S. Wuttke

Characterization of Protein-Protein Interactions Critical for Poliovirus Replication: Analysis of 3AB and VPg Binding to the RNA-Dependent RNA Polymerase
J. Virol. 2007 81: 6369-6378. [Abstract] [Full Text] [PDF]  

Latasha Day, Charles M. Chau, Michael Nebozhyn, Andrew J. Rennekamp, Michael Showe, and Paul M. Lieberman

Chromatin Profiling of Epstein-Barr Virus Latency Control Region
J. Virol. 2007 81: 6389-6401. [Abstract] [Full Text] [PDF]  

Veerasamy Ravichandran, Peter N. Jensen, and Eugene O. Major

MEK1/2 Inhibitors Block Basal and Transforming Growth Factor ß1-Stimulated JC Virus Multiplication
J. Virol. 2007 81: 6412-6418. [Abstract] [Full Text] [PDF]  

Andrea S. Bertke, Amita Patel, and Philip R. Krause

Herpes Simplex Virus Latency-Associated Transcript Sequence Downstream of the Promoter Influences Type-Specific Reactivation and Viral Neurotropism
J. Virol. 2007 81: 6605-6613. [Abstract] [Full Text] [PDF]  

Torunn Pedersen, Astrid Skjesol, and Jorunn B. Jørgensen

VP3, a Structural Protein of Infectious Pancreatic Necrosis Virus, Interacts with RNA-Dependent RNA Polymerase VP1 and with Double-Stranded RNA
J. Virol. 2007 81: 6652-6663. [Abstract] [Full Text] [PDF]  

Michael J. Keller, Allen W. Wu, Janet I. Andrews, Patrick W. McGonagill, Eric E. Tibesar, and Jeffery L. Meier

Reversal of Human Cytomegalovirus Major Immediate-Early Enhancer/Promoter Silencing in Quiescently Infected Cells via the Cyclic AMP Signaling Pathway
J. Virol. 2007 81: 6669-6681. [Abstract] [Full Text] [PDF]  

David Derse, Bruce Crise, Yuan Li, Gerald Princler, Nicole Lum, Claudia Stewart, Connor F. McGrath, Stephen H. Hughes, David J. Munroe, and Xiaolin Wu

Human T-Cell Leukemia Virus Type 1 Integration Target Sites in the Human Genome: Comparison with Those of Other Retroviruses
J. Virol. 2007 81: 6731-6741. [Abstract] [Full Text] [PDF] [Supplemental material]  

Elaine Wong, Ting-Ting Wu, Nichole Reyes, Hongyu Deng, and Ren Sun

Murine Gammaherpesvirus 68 Open Reading Frame 24 Is Required for Late Gene Expression after DNA Replication
J. Virol. 2007 81: 6761-6764. [Abstract] [Full Text] [PDF]  

Robert E. White, Lindsay Carline, and Martin J. Allday

Mutagenesis of the Herpesvirus Saimiri Terminal Repeat Region Reveals Important Elements for Virus Production
J. Virol. 2007 81: 6765-6770. [Abstract] [Full Text] [PDF]  

Pathogenesis and Immunity:

Jeffrey M. Milush, Kelly Stefano-Cole, Kimberli Schmidt, Andre Durudas, Ivona Pandrea, and Donald L. Sodora

Mucosal Innate Immune Response Associated with a Timely Humoral Immune Response and Slower Disease Progression after Oral Transmission of Simian Immunodeficiency Virus to Rhesus Macaques
J. Virol. 2007 81: 6175-6186. [Abstract] [Full Text] [PDF]  

E. S. Gray, P. L. Moore, I. A. Choge, J. M. Decker, F. Bibollet-Ruche, H. Li, N. Leseka, F. Treurnicht, K. Mlisana, G. M. Shaw, S. S. Abdool Karim, C. Williamson, L. Morris and the CAPRISA 002 Study Team

Neutralizing Antibody Responses in Acute Human Immunodeficiency Virus Type 1 Subtype C Infection
J. Virol. 2007 81: 6187-6196. [Abstract] [Full Text] [PDF]  

Marlene S. Orandle, Ronald S. Veazey, and Andrew A. Lackner

Enteric Ganglionitis in Rhesus Macaques Infected with Simian Immunodeficiency Virus
J. Virol. 2007 81: 6265-6275. [Abstract] [Full Text] [PDF]  

Mirko Kummer, Nadine M. Turza, Petra Muhl-Zurbes, Matthias Lechmann, Chris Boutell, Robert S. Coffin, Roger D. Everett, Alexander Steinkasserer, and Alexander T. Prechtel

Herpes Simplex Virus Type 1 Induces CD83 Degradation in Mature Dendritic Cells with Immediate-Early Kinetics via the Cellular Proteasome
J. Virol. 2007 81: 6326-6338. [Abstract] [Full Text] [PDF] [Supplemental material]  

Zane Kraft, Nina R. Derby, Ruth A. McCaffrey, Rachel Niec, Wendy M. Blay, Nancy L. Haigwood, Eirini Moysi, Cheryl J. Saunders, Terri Wrin, Christos J. Petropoulos, M. Juliana McElrath, and Leonidas Stamatatos

Macaques Infected with a CCR5-Tropic Simian/Human Immunodeficiency Virus (SHIV) Develop Broadly Reactive Anti-HIV Neutralizing Antibodies
J. Virol. 2007 81: 6402-6411. [Abstract] [Full Text] [PDF]  

Kate L. Graham, Joanne A. O'Donnell, Yan Tan, Natalie Sanders, Emma M. Carrington, Janette Allison, and Barbara S. Coulson

Rotavirus Infection of Infant and Young Adult Nonobese Diabetic Mice Involves Extraintestinal Spread and Delays Diabetes Onset
J. Virol. 2007 81: 6446-6458. [Abstract] [Full Text] [PDF]  

Ricardo Carrion, Jr., Kathleen Brasky, Keith Mansfield, Curtis Johnson, Monica Gonzales, Anysha Ticer, Igor Lukashevich, Suzette Tardif, and Jean Patterson

Lassa Virus Infection in Experimentally Infected Marmosets: Liver Pathology and Immunophenotypic Alterations in Target Tissues
J. Virol. 2007 81: 6482-6490. [Abstract] [Full Text] [PDF]  

Anju Singh, Marcel Wüthrich, Bruce Klein, and M. Suresh

Indirect Regulation of CD4 T-Cell Responses by Tumor Necrosis Factor Receptors in an Acute Viral Infection
J. Virol. 2007 81: 6502-6512. [Abstract] [Full Text] [PDF]  

Amandeep K. Dhillon, Helen Donners, Ralph Pantophlet, Welkin E. Johnson, Julie M. Decker, George M. Shaw, Fang-Hua Lee, Douglas D. Richman, Robert W. Doms, Guido Vanham, and Dennis R. Burton

Dissecting the Neutralizing Antibody Specificities of Broadly Neutralizing Sera from Human Immunodeficiency Virus Type 1-Infected Donors
J. Virol. 2007 81: 6548-6562. [Abstract] [Full Text] [PDF]  

Meghann Teague Getts, Byung S. Kim, and Stephen D. Miller

Differential Outcome of Tolerance Induction in Naive versus Activated Theiler's Virus Epitope-Specific CD8⁺ Cytotoxic T Cells
J. Virol. 2007 81: 6584-6593. [Abstract] [Full Text] [PDF]  

Jing Qu, Jian Ye, and Rongxiang Fang

Artificial MicroRNA-Mediated Virus Resistance in Plants
J. Virol. 2007 81: 6690-6699. [Abstract] [Full Text] [PDF]  

A. J. Frater, H. Brown, A. Oxenius, H. F. Günthard, B. Hirschel, N. Robinson, A. J. Leslie, R. Payne, H. Crawford, A. Prendergast, C. Brander, P. Kiepiela, B. D. Walker, P. J. R. Goulder, A. McLean, R. E. Phillips and the Swiss HIV-Cohort Study

Effective T-Cell Responses Select Human Immunodeficiency Virus Mutants and Slow Disease Progression
J. Virol. 2007 81: 6742-6751. [Abstract] [Full Text] [PDF] [Supplemental material]  

Structure and Assembly:

Laurent Chatel-Chaix, Levon Abrahamyan, Céline Fréchina, Andrew J. Mouland, and Luc DesGroseillers

The Host Protein Staufen1 Participates in Human Immunodeficiency Virus Type 1 Assembly in Live Cells by Influencing pr55^Gag Multimerization
J. Virol. 2007 81: 6216-6230. [Abstract] [Full Text] [PDF]  

Christopher B. Whitehurst, Erik J. Soderblom, Michelle L. West, Raquel Hernandez, Michael B. Goshe, and Dennis T. Brown

Location and Role of Free Cysteinyl Residues in the Sindbis Virus E1 and E2 Glycoproteins
J. Virol. 2007 81: 6231-6240. [Abstract] [Full Text] [PDF]  

Umesh Katpally and Thomas J. Smith

Pocket Factors Are Unlikely To Play a Major Role in the Life Cycle of Human Rhinovirus
J. Virol. 2007 81: 6307-6315. [Abstract] [Full Text] [PDF]  

Kui Yang, Fred Homa, and Joel D. Baines

Putative Terminase Subunits of Herpes Simplex Virus 1 Form a Complex in the Cytoplasm and Interact with Portal Protein in the Nucleus
J. Virol. 2007 81: 6419-6433. [Abstract] [Full Text] [PDF]  

Amanda K. Dalton, Danso Ako-Adjei, Paul S. Murray, Diana Murray, and Volker M. Vogt

Electrostatic Interactions Drive Membrane Association of the Human Immunodeficiency Virus Type 1 Gag MA Domain
J. Virol. 2007 81: 6434-6445. [Abstract] [Full Text] [PDF]  

Chinmay G. Patkar, Christopher T. Jones, Yu-hsuan Chang, Ranjit Warrier, and Richard J. Kuhn

Functional Requirements of the Yellow Fever Virus Capsid Protein
J. Virol. 2007 81: 6471-6481. [Abstract] [Full Text] [PDF]  

Jun-Young Seo and William J. Britt

Cytoplasmic Envelopment of Human Cytomegalovirus Requires the Postlocalization Function of Tegument Protein pp28 within the Assembly Compartment
J. Virol. 2007 81: 6536-6547. [Abstract] [Full Text] [PDF]  

Samuel J. Rulli, Jr., Catherine S. Hibbert, Jane Mirro, Thoru Pederson, Shyam Biswal, and Alan Rein

Selective and Nonselective Packaging of Cellular RNAs in Retrovirus Particles
J. Virol. 2007 81: 6623-6631. [Abstract] [Full Text] [PDF]  

Louis A. Altamura, Andrea Bertolotti-Ciarlet, Jeffrey Teigler, Jason Paragas, Connie S. Schmaljohn, and Robert W. Doms

Identification of a Novel C-Terminal Cleavage of Crimean-Congo Hemorrhagic Fever Virus PreG_N That Leads to Generation of an NS_M Protein
J. Virol. 2007 81: 6632-6642. [Abstract] [Full Text] [PDF]  

Jeremiah S. Joseph, Kumar Singh Saikatendu, Vanitha Subramanian, Benjamin W. Neuman, Michael J. Buchmeier, Raymond C. Stevens, and Peter Kuhn

Crystal Structure of a Monomeric Form of Severe Acute Respiratory Syndrome Coronavirus Endonuclease nsp15 Suggests a Role for Hexamerization as an Allosteric Switch
J. Virol. 2007 81: 6700-6708. [Abstract] [Full Text] [PDF]  

Shih-Cheng Chen, Erwin van den Born, Sjoerd H. E. van den Worm, Cornelis W. A. Pleij, Eric J. Snijder, and René C. L. Olsthoorn

New Structure Model for the Packaging Signal in the Genome of Group IIa Coronaviruses
J. Virol. 2007 81: 6771-6774. [Abstract] [Full Text] [PDF]  

Virus-Cell Interactions:

Marisa K. Isaacson, Adam L. Feire, and Teresa Compton

Epidermal Growth Factor Receptor Is Not Required for Human Cytomegalovirus Entry or Signaling
J. Virol. 2007 81: 6241-6247. [Abstract] [Full Text] [PDF]  

Timothy R. Wagenaar and Bernard Moss

Association of Vaccinia Virus Fusion Regulatory Proteins with the Multicomponent Entry/Fusion Complex
J. Virol. 2007 81: 6286-6293. [Abstract] [Full Text] [PDF]  

Maria Kalamvoki and Bernard Roizman

Bcl-2 Blocks Accretion or Depletion of Stored Calcium but Has No Effect on the Redistribution of IP3 Receptor I Mediated by Glycoprotein E of Herpes Simplex Virus 1
J. Virol. 2007 81: 6316-6325. [Abstract] [Full Text] [PDF]  

Ying-Xim Tan, Timothy H. P. Tan, Marvin J.-R. Lee, Puay-Yoke Tham, Vithiagaran Gunalan, Julian Druce, Chris Birch, Mike Catton, Nai Yang Fu, Victor C. Yu, and Yee-Joo Tan

Induction of Apoptosis by the Severe Acute Respiratory Syndrome Coronavirus 7a Protein Is Dependent on Its Interaction with the Bcl-X_L Protein
J. Virol. 2007 81: 6346-6355. [Abstract] [Full Text] [PDF]  

Fan Mou, Tom Forest, and Joel D. Baines

U_S3 of Herpes Simplex Virus Type 1 Encodes a Promiscuous Protein Kinase That Phosphorylates and Alters Localization of Lamin A/C in Infected Cells
J. Virol. 2007 81: 6459-6470. [Abstract] [Full Text] [PDF]  

Michael B. Gill, Jeffery L. Kutok, and Joyce D. Fingeroth

Epstein-Barr Virus Thymidine Kinase Is a Centrosomal Resident Precisely Localized to the Periphery of Centrioles
J. Virol. 2007 81: 6523-6535. [Abstract] [Full Text] [PDF]  

Robert E. Means, Sabine M. Lang, and Jae U. Jung

The Kaposi's Sarcoma-Associated Herpesvirus K5 E3 Ubiquitin Ligase Modulates Targets by Multiple Molecular Mechanisms
J. Virol. 2007 81: 6573-6583. [Abstract] [Full Text] [PDF]  

Yoshiko Usami, Sergei Popov, and Heinrich G. Göttlinger

Potent Rescue of Human Immunodeficiency Virus Type 1 Late Domain Mutants by ALIX/AIP1 Depends on Its CHMP4 Binding Site
J. Virol. 2007 81: 6614-6622. [Abstract] [Full Text] [PDF]  

Nam-Joon Cho, Kwang Ho Cheong, ChoongHo Lee, Curtis W. Frank, and Jeffrey S. Glenn

Binding Dynamics of Hepatitis C Virus' NS5A Amphipathic Peptide to Cell and Model Membranes
J. Virol. 2007 81: 6682-6689. [Abstract] [Full Text] [PDF]  

Tathagata Choudhuri, Subhash C. Verma, Ke Lan, Masanao Murakami, and Erle S. Robertson

The ATM/ATR Signaling Effector Chk2 Is Targeted by Epstein-Barr Virus Nuclear Antigen 3C To Release the G₂/M Cell Cycle Block
J. Virol. 2007 81: 6718-6730. [Abstract] [Full Text] [PDF]  

Kavitha Gowrishankar, Barry Slobedman, Anthony L. Cunningham, Monica Miranda-Saksena, Ross A. Boadle, and Allison Abendroth

Productive Varicella-Zoster Virus Infection of Cultured Intact Human Ganglia
J. Virol. 2007 81: 6752-6756. [Abstract] [Full Text] [PDF]  

Jun Chen and Aleem Siddiqui

Hepatitis B Virus X Protein Stimulates the Mitochondrial Translocation of Raf-1 via Oxidative Stress
J. Virol. 2007 81: 6757-6760. [Abstract] [Full Text] [PDF]  

Vaccines and Antiviral Agents:

Alan C. Jackson, Courtney A. Scott, James Owen, Simon C. Weli, and John P. Rossiter

Therapy with Minocycline Aggravates Experimental Rabies in Mice
J. Virol. 2007 81: 6248-6253. [Abstract] [Full Text] [PDF]  

Stacy M. Horner and Daniel DiMaio

The DNA Binding Domain of a Papillomavirus E2 Protein Programs a Chimeric Nuclease To Cleave Integrated Human Papillomavirus DNA in HeLa Cervical Carcinoma Cells
J. Virol. 2007 81: 6254-6264. [Abstract] [Full Text] [PDF]  

Alexander Bukreyev, Pierre E. Rollin, Mallory K. Tate, Lijuan Yang, Sherif R. Zaki, Wun-Ju Shieh, Brian R. Murphy, Peter L. Collins, and Anthony Sanchez

Successful Topical Respiratory Tract Immunization of Primates against Ebola Virus
J. Virol. 2007 81: 6379-6388. [Abstract] [Full Text] [PDF]  

Raghavan Chinnadurai, Devi Rajan, Jan Münch, and Frank Kirchhoff

Human Immunodeficiency Virus Type 1 Variants Resistant to First- and Second-Version Fusion Inhibitors and Cytopathic in Ex Vivo Human Lymphoid Tissue
J. Virol. 2007 81: 6563-6572. [Abstract] [Full Text] [PDF]  

Kimberly McCoy, Nia Tatsis, Birgit Korioth-Schmitz, Marcio O. Lasaro, Scott E. Hensley, Shih-Wen Lin, Yan Li, Wynetta Giles-Davis, Ann Cun, Dongming Zhou, Zhiquan Xiang, Norman L. Letvin, and Hildegund C. J. Ertl

Effect of Preexisting Immunity to Adenovirus Human Serotype 5 Antigens on the Immune Responses of Nonhuman Primates to Vaccine Regimens Based on Human- or Chimpanzee-Derived Adenovirus Vectors
J. Virol. 2007 81: 6594-6604. [Abstract] [Full Text] [PDF]  

Transformation and Oncogenesis:

Charles E. Wood, Zigui Chen, J. Mark Cline, Brigitte E. Miller, and Robert D. Burk

Characterization and Experimental Transmission of an Oncogenic Papillomavirus in Female Macaques
J. Virol. 2007 81: 6339-6345. [Abstract] [Full Text] [PDF]  

Genetic Diversity and Evolution:

Renée Lapointe, Kohjiro Tanaka, Walter E. Barney, James B. Whitfield, Jonathan C. Banks, Catherine Béliveau, Don Stoltz, Bruce A. Webb, and Michel Cusson

Genomic and Morphological Features of a Banchine Polydnavirus: Comparison with Bracoviruses and Ichnoviruses
J. Virol. 2007 81: 6491-6501. [Abstract] [Full Text] [PDF] [Supplemental material]  

Xiao-Hong Wang, Dale M. Netski, Jacquie Astemborski, Shruti H. Mehta, Michael S. Torbenson, David L. Thomas, and Stuart C. Ray

Progression of Fibrosis during Chronic Hepatitis C Is Associated with Rapid Virus Evolution
J. Virol. 2007 81: 6513-6522. [Abstract] [Full Text] [PDF]  

Selene Zárate, Sergei L. Kosakovsky Pond, Paul Shapshak, and Simon D. W. Frost

Comparative Study of Methods for Detecting Sequence Compartmentalization in Human Immunodeficiency Virus Type 1
J. Virol. 2007 81: 6643-6651. [Abstract] [Full Text] [PDF]  

Isabel S. Novella, Bonnie E. Ebendick-Corpus, Selene Zárate, and Eric L. Miller

Emergence of Mammalian Cell-Adapted Vesicular Stomatitis Virus from Persistent Infections of Insect Vector Cells
J. Virol. 2007 81: 6664-6668. [Abstract] [Full Text] [PDF]  

Xuhua Tang, Jinlu Wu, J. Sivaraman, and Choy Leong Hew

Crystal Structures of Major Envelope Proteins VP26 and VP28 from White Spot Syndrome Virus Shed Light on Their Evolutionary Relationship
J. Virol. 2007 81: 6709-6717. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.