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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2006 80: 3693. [Full Text] [PDF] FREE [Reprints and Permissions]  

Genome Replication and Regulation of Viral Gene Expression:

Orly Ardon, Erik S. Zimmerman, Joshua L. Andersen, Jason L. DeHart, Jana Blackett, and Vicente Planelles

Induction of G₂ Arrest and Binding to Cyclophilin A Are Independent Phenotypes of Human Immunodeficiency Virus Type 1 Vpr
J. Virol. 2006 80: 3694-3700. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David J. Dismuke and Christopher Aiken

Evidence for a Functional Link between Uncoating of the Human Immunodeficiency Virus Type 1 Core and Nuclear Import of the Viral Preintegration Complex
J. Virol. 2006 80: 3712-3720. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hiroyuki Mizumoto, Hiro-oki Iwakawa, Masanori Kaido, Kazuyuki Mise, and Tetsuro Okuno

Cap-Independent Translation Mechanism of Red Clover Necrotic Mosaic Virus RNA2 Differs from That of RNA1 and Is Linked to RNA Replication
J. Virol. 2006 80: 3781-3791. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wei Li, Tanja J. Minova-Foster, Daniel D. Norton, and Martin I. Muggeridge

Identification of Functional Domains in Herpes Simplex Virus 2 Glycoprotein B
J. Virol. 2006 80: 3792-3800. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jae-Hyung Lee, Sean C. Murphy, Michael Belshan, Wendy O. Sparks, Yvonne Wannemuehler, Sijun Liu, Thomas J. Hope, Drena Dobbs, and Susan Carpenter

Characterization of Functional Domains of Equine Infectious Anemia Virus Rev Suggests a Bipartite RNA-Binding Domain
J. Virol. 2006 80: 3844-3852. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dustin T. Petrik, Kimberly P. Schmitt, and Mark F. Stinski

Inhibition of Cellular DNA Synthesis by the Human Cytomegalovirus IE86 Protein Is Necessary for Efficient Virus Replication
J. Virol. 2006 80: 3872-3883. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ilker K. Sariyer, Ilhan Akan, Victoria Palermo, Jennifer Gordon, Kamel Khalili, and Mahmut Safak

Phosphorylation Mutants of JC Virus Agnoprotein Are Unable To Sustain the Viral Infection Cycle
J. Virol. 2006 80: 3893-3903. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wen-Pin Tzeng, Jason D. Matthews, and Teryl K. Frey

Analysis of Rubella Virus Capsid Protein-Mediated Enhancement of Replicon Replication and Mutant Rescue
J. Virol. 2006 80: 3966-3974. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Regina M. Kofler, Verena M. Hoenninger, Caroline Thurner, and Christian W. Mandl

Functional Analysis of the Tick-Borne Encephalitis Virus Cyclization Elements Indicates Major Differences between Mosquito-Borne and Tick-Borne Flaviviruses
J. Virol. 2006 80: 4099-4113. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elena Frolova, Rodion Gorchakov, Natalia Garmashova, Svetlana Atasheva, Leoncio A. Vergara, and Ilya Frolov

Formation of nsP3-Specific Protein Complexes during Sindbis Virus Replication
J. Virol. 2006 80: 4122-4134. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Saskia L. Smits, Eric J. Snijder, and Raoul J. de Groot

Characterization of a Torovirus Main Proteinase
J. Virol. 2006 80: 4157-4167. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dagmar Knebel-Mörsdorf, Ilja Quadt, Yi Li, Laura Montier, and Linda A. Guarino

Expression of Baculovirus Late and Very Late Genes Depends on LEF-4, a Component of the Viral RNA Polymerase Whose Guanyltransferase Function Is Essential
J. Virol. 2006 80: 4168-4173. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Structure and Assembly:

John H. Connor, Margie O. McKenzie, and Douglas S. Lyles

Role of Residues 121 to 124 of Vesicular Stomatitis Virus Matrix Protein in Virus Assembly and Virus-Host Interaction
J. Virol. 2006 80: 3701-3711. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shinji Watanabe, Takeshi Noda, and Yoshihiro Kawaoka

Functional Mapping of the Nucleoprotein of Ebola Virus
J. Virol. 2006 80: 3743-3751. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kirsi Harila, Ian Prior, Mathilda Sjöberg, Antti Salminen, Jorma Hinkula, and Maarit Suomalainen

Vpu and Tsg101 Regulate Intracellular Targeting of the Human Immunodeficiency Virus Type 1 Core Protein Precursor Pr55^gag
J. Virol. 2006 80: 3765-3772. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Israrul H. Ansari, Byungjoon Kwon, Fernando A. Osorio, and Asit K. Pattnaik

Influence of N-Linked Glycosylation of Porcine Reproductive and Respiratory Syndrome Virus GP5 on Virus Infectivity, Antigenicity, and Ability To Induce Neutralizing Antibodies
J. Virol. 2006 80: 3994-4004. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wiebke Schormann, Anke Kraft, Dirk Ponsel, and Volker Bruss

Hepatitis B Virus Particle Formation in the Absence of Pregenomic RNA and Reverse Transcriptase
J. Virol. 2006 80: 4187-4190. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pathogenesis and Immunity:

Jenna Rychert, Nedra Lacour, and Angela Martin Amedee

Genetic Analysis of Simian Immunodeficiency Virus Expressed in Milk and Selectively Transmitted through Breastfeeding
J. Virol. 2006 80: 3721-3731. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jelle Matthijnssens, Mustafizur Rahman, Vito Martella, Yang Xuelei, Sofie De Vos, Karolien De Leener, Max Ciarlet, Canio Buonavoglia, and Marc Van Ranst

Full Genomic Analysis of Human Rotavirus Strain B4106 and Lapine Rotavirus Strain 30/96 Provides Evidence for Interspecies Transmission
J. Virol. 2006 80: 3801-3810. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Vito Racanelli, Maria Antonia Frassanito, Patrizia Leone, Maria Galiano, Valli De Re, Franco Silvestris, and Franco Dammacco

Antibody Production and In Vitro Behavior of CD27-Defined B-Cell Subsets: Persistent Hepatitis C Virus Infection Changes the Rules
J. Virol. 2006 80: 3923-3934. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sadik H. Kassim, Naveen K. Rajasagi, Xiangyi Zhao, Robert Chervenak, and Stephen R. Jennings

In Vivo Ablation of CD11c-Positive Dendritic Cells Increases Susceptibility to Herpes Simplex Virus Type 1 Infection and Diminishes NK and T-Cell Responses
J. Virol. 2006 80: 3985-3993. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Véronique Voisin, Corinne Barat, Trang Hoang, and Eric Rassart

Novel Insights into the Pathogenesis of the Graffi Murine Leukemia Retrovirus
J. Virol. 2006 80: 4026-4037. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lauren M. Hook, John M. Lubinski, Ming Jiang, Michael K. Pangburn, and Harvey M. Friedman

Herpes Simplex Virus Type 1 and 2 Glycoprotein C Prevents Complement-Mediated Neutralization Induced by Natural Immunoglobulin M Antibody
J. Virol. 2006 80: 4038-4046. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. Nugent, I. Birch-Machin, K. C. Smith, J. A. Mumford, Z. Swann, J. R. Newton, R. J. Bowden, G. P. Allen, and N. Davis-Poynter

Analysis of Equid Herpesvirus 1 Strain Variation Reveals a Point Mutation of the DNA Polymerase Strongly Associated with Neuropathogenic versus Nonneuropathogenic Disease Outbreaks
J. Virol. 2006 80: 4047-4060. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brian D. Poole, Jing Zhou, Amy Grote, Adam Schiffenbauer, and Stanley J. Naides

Apoptosis of Liver-Derived Cells Induced by Parvovirus B19 Nonstructural Protein
J. Virol. 2006 80: 4114-4121. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shuyang Yu, Mifang Liang, BaoLiang Fan, Hongtao Xu, Chuan Li, Quanfu Zhang, Dexin Li, Bo Tang, Shijie Li, Yunping Dai, Meili Wang, Min Zheng, Bingxue Yan, Qinghong Zhu, and Ning Li

Maternally Derived Recombinant Human Anti-Hantavirus Monoclonal Antibodies Are Transferred to Mouse Offspring during Lactation and Neutralize Virus In Vitro
J. Virol. 2006 80: 4183-4186. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Xiuju Lu, Amelia K. Pinto, Ann M. Kelly, Kathy S. Cho, and Ann B. Hill

Murine Cytomegalovirus Interference with Antigen Presentation Contributes to the Inability of CD8 T Cells To Control Virus in the Salivary Gland
J. Virol. 2006 80: 4200-4202. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vaccines and Antiviral Agents:

Ranajit Pal, David Venzon, Sampa Santra, Vaniambadi S. Kalyanaraman, David C. Montefiori, Lindsey Hocker, Lauren Hudacik, Nicolas Rose, Janos Nacsa, Yvette Edghill-Smith, Marcin Moniuszko, Zdenek Hel, Igor M. Belyakov, Jay A. Berzofsky, Robyn Washington Parks, Phillip D. Markham, Norman L. Letvin, Jim Tartaglia, and Genoveffa Franchini

Systemic Immunization with an ALVAC-HIV-1/Protein Boost Vaccine Strategy Protects Rhesus Macaques from CD4⁺ T-Cell Loss and Reduces both Systemic and Mucosal Simian-Human Immunodeficiency Virus SHIV_KU2 RNA Levels
J. Virol. 2006 80: 3732-3742. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Davide Agnello, Christine A. Hervé, Amandine Lavaux, Magali Darniot, Patrice Guillon, Annie Charpilienne, and Pierre Pothier

Intrarectal Immunization with Rotavirus 2/6 Virus-Like Particles Induces an Antirotavirus Immune Response Localized in the Intestinal Mucosa and Protects against Rotavirus Infection in Mice
J. Virol. 2006 80: 3823-3832. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wai-Ping Woo, Tracy Doan, Karen A. Herd, Hans-Jürgen Netter, and Robert W. Tindle

Hepatitis B Surface Antigen Vector Delivers Protective Cytotoxic T-Lymphocyte Responses to Disease-Relevant Foreign Epitopes
J. Virol. 2006 80: 3975-3984. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hsu-Tso Ho, Li Fan, Beata Nowicka-Sans, Brian McAuliffe, Chang-Ben Li, Gregory Yamanaka, Nannan Zhou, Hua Fang, Ira Dicker, Richard Dalterio, Yi-Fei Gong, Tao Wang, Zhiwei Yin, Yasutsugu Ueda, John Matiskella, John Kadow, Paul Clapham, James Robinson, Richard Colonno, and Pin-Fang Lin

Envelope Conformational Changes Induced by Human Immunodeficiency Virus Type 1 Attachment Inhibitors Prevent CD4 Binding and Downstream Entry Events
J. Virol. 2006 80: 4017-4025. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jong-Soo Lee, Haryoung Poo, Dong P. Han, Seung-Pyo Hong, Kwang Kim, Michael W. Cho, Eun Kim, Moon-Hee Sung, and Chul-Joong Kim

Mucosal Immunization with Surface-Displayed Severe Acute Respiratory Syndrome Coronavirus Spike Protein on Lactobacillus casei Induces Neutralizing Antibodies in Mice
J. Virol. 2006 80: 4079-4087. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Coralie Moriette, Monique LeBerre, Annie Lamoureux, Thanh-Lan Lai, and Michel Brémont

Recovery of a Recombinant Salmonid Alphavirus Fully Attenuated and Protective for Rainbow Trout
J. Virol. 2006 80: 4088-4098. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Virus-Cell Interactions:

Alice P. W. Poon, Luca Benetti, and Bernard Roizman

U_S3 and U_S3.5 Protein Kinases of Herpes Simplex Virus 1 Differ with Respect to Their Functions in Blocking Apoptosis and in Virion Maturation and Egress
J. Virol. 2006 80: 3752-3764. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. Charles Whitbeck, Yi Zuo, Richard S. B. Milne, Gary H. Cohen, and Roselyn J. Eisenberg

Stable Association of Herpes Simplex Virus with Target Membranes Is Triggered by Low pH in the Presence of the gD Receptor, HVEM
J. Virol. 2006 80: 3773-3780. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Zhigang Zhang, David L. Evers, Joseph F. McCarville, Jean-Christophe Dantonel, Shu-Mei Huong, and Eng-Shang Huang

Evidence that the Human Cytomegalovirus IE2-86 Protein Binds mdm2 and Facilitates mdm2 Degradation
J. Virol. 2006 80: 3833-3843. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ryan T. Saffert and Robert F. Kalejta

Inactivating a Cellular Intrinsic Immune Defense Mediated by Daxx Is the Mechanism through Which the Human Cytomegalovirus pp71 Protein Stimulates Viral Immediate-Early Gene Expression
J. Virol. 2006 80: 3863-3871. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fang He, Beau J. Fenner, Andrew K. Godwin, and Jimmy Kwang

White Spot Syndrome Virus Open Reading Frame 222 Encodes a Viral E3 Ligase and Mediates Degradation of a Host Tumor Suppressor via Ubiquitination
J. Virol. 2006 80: 3884-3892. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thomas Krey, Anke Himmelreich, Manuela Heimann, Christian Menge, Heinz-Jürgen Thiel, Karin Maurer, and Till Rümenapf

Function of Bovine CD46 as a Cellular Receptor for Bovine Viral Diarrhea Virus Is Determined by Complement Control Protein 1
J. Virol. 2006 80: 3912-3922. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mariela A. Cuadras, Bruno B. Bordier, Jose L. Zambrano, Juan E. Ludert, and Harry B. Greenberg

Dissecting Rotavirus Particle-Raft Interaction with Small Interfering RNAs: Insights into Rotavirus Transit through the Secretory Pathway
J. Virol. 2006 80: 3935-3946. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Agnès Gardet, Michelyne Breton, Philippe Fontanges, Germain Trugnan, and Serge Chwetzoff

Rotavirus Spike Protein VP4 Binds to and Remodels Actin Bundles of the Epithelial Brush Border into Actin Bodies
J. Virol. 2006 80: 3947-3956. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Joseph S. Orlando, Todd L. Astor, Scott A. Rundle, and Priscilla A. Schaffer

The Products of the Herpes Simplex Virus Type 1 Immediate-Early U_S1/U_S1.5 Genes Downregulate Levels of S-Phase-Specific Cyclins and Facilitate Virus Replication in S-Phase Vero Cells
J. Virol. 2006 80: 4005-4016. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Melvyn W. Yap, Mark P. Dodding, and Jonathan P. Stoye

Trim-Cyclophilin A Fusion Proteins Can Restrict Human Immunodeficiency Virus Type 1 Infection at Two Distinct Phases in the Viral Life Cycle
J. Virol. 2006 80: 4061-4067. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

O. B. Spiller, L. Mark, C. E. Blue, D. G. Proctor, J. A. Aitken, A. M. Blom, and D. J. Blackbourn

Dissecting the Regions of Virion-Associated Kaposi's Sarcoma-Associated Herpesvirus Complement Control Protein Required for Complement Regulation and Cell Binding
J. Virol. 2006 80: 4068-4078. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Brian Dove, Gavin Brooks, Katrina Bicknell, Torsten Wurm, and Julian A. Hiscox

Cell Cycle Perturbations Induced by Infection with the Coronavirus Infectious Bronchitis Virus and Their Effect on Virus Replication
J. Virol. 2006 80: 4147-4156. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kathryn Schornberg, Shutoku Matsuyama, Kirsten Kabsch, Sue Delos, Amy Bouton, and Judith White

Role of Endosomal Cathepsins in Entry Mediated by the Ebola Virus Glycoprotein
J. Virol. 2006 80: 4174-4178. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shuzo Urata, Takeshi Noda, Yoshihiro Kawaoka, Hideyoshi Yokosawa, and Jiro Yasuda

Cellular Factors Required for Lassa Virus Budding
J. Virol. 2006 80: 4191-4195. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Genetic Diversity and Evolution:

Monir Shababi, June Bourque, Karuppaiah Palanichelvam, Anthony Cole, Dong Xu, Xiu-Feng Wan, and James Schoelz

The Ribosomal Shunt Translation Strategy of Cauliflower Mosaic Virus Has Evolved from Ancient Long Terminal Repeats
J. Virol. 2006 80: 3811-3822. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Molly OhAinle, Julie A. Kerns, Harmit S. Malik, and Michael Emerman

Adaptive Evolution and Antiviral Activity of the Conserved Mammalian Cytidine Deaminase APOBEC3H
J. Virol. 2006 80: 3853-3862. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pierre Rivailler, Amitinder Kaur, R. Paul Johnson, and Fred Wang

Genomic Sequence of Rhesus Cytomegalovirus 180.92: Insights into the Coding Potential of Rhesus Cytomegalovirus
J. Virol. 2006 80: 4179-4182. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Mark A. Winters, Seth L. Welles, and Mark Holodniy

Hepatitis C Virus Protease Gene Diversity in Patients Coinfected with Human Immunodeficiency Virus
J. Virol. 2006 80: 4196-4199. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gene Delivery:

Gabriel Glockzin, Klaus Mantwill, Karsten Jurchott, Alexandra Bernshausen, Axel Ladhoff, Hans-Dieter Royer, Bernd Gansbacher, and Per Sonne Holm

Characterization of the Recombinant Adenovirus Vector AdYB-1: Implications for Oncolytic Vector Development
J. Virol. 2006 80: 3904-3911. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cellular Response to Infection:

Karen Y. Twu, Diana L. Noah, Ping Rao, Rei-Lin Kuo, and Robert M. Krug

The CPSF30 Binding Site on the NS1A Protein of Influenza A Virus Is a Potential Antiviral Target
J. Virol. 2006 80: 3957-3965. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christos Kenoutis, Rodica C. Efrose, Luc Swevers, Alexandros A. Lavdas, Maria Gaitanou, Rebecca Matsas, and Kostas Iatrou

Baculovirus-Mediated Gene Delivery into Mammalian Cells Does Not Alter Their Transcriptional and Differentiating Potential but Is Accompanied by Early Viral Gene Expression
J. Virol. 2006 80: 4135-4146. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Heesoon Chang, Dirk P. Dittmer, Young C. Shin, Youngkwon Hong, and Jae U. Jung

Role of Notch Signal Transduction in Kaposi's Sarcoma-Associated Herpesvirus Gene Expression
J. Virol. 2006 80: 4203. [Full Text] [PDF] [Reprints and Permissions]  

Yau-Heiu Hsu, Hsin-Chuan Chen, Jeannie Cheng, Padmanaban Annamalai, Bin-Yen Lin, Chiang-Tai Wu, Wen-Bin Yeh, and Na-Sheng Lin

Crucial Role of the 5' Conserved Structure of Bamboo Mosaic Virus Satellite RNA in Downregulation of Helper Viral RNA Replication
J. Virol. 2006 80: 4204. [Full Text] [PDF] [Reprints and Permissions]  

Author's Correction:

Liwen You, Daniel Garwicz, and Thorsteinn Rögnvaldsson

Comprehensive Bioinformatic Analysis of the Specificity of Human Immunodeficiency Virus Type 1 Protease
J. Virol. 2006 80: 4205. [Full Text] [PDF] [Reprints and Permissions]  

Zhi-yong Yang, Bimal K. Chakrabarti, Ling Xu, Brent Welcher, Wing-pui Kong, Kwanyee Leung, Amos Panet, John R. Mascola, and Gary J. Nabel

Selective Modification of Variable Loops Alters Tropism and Enhances Immunogenicity of Human Immunodeficiency Virus Type 1 Envelope
J. Virol. 2006 80: 4206. [Full Text] [PDF] [Reprints and Permissions]  

Isabel S. Novella, Daniel D. Reissig, and Claus O. Wilke

Density-Dependent Selection in Vesicular Stomatitis Virus
J. Virol. 2006 80: 4207. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.