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Contents: February 2006, Volume 80, Issue 4        Spotlight        Virus-Cell Interactions        Pathogenesis and Immunity        Genetic Diversity and Evolution        Vaccines and Antiviral Agents        Genome Replication and Regulation of Viral Gene Expression        Gene Delivery        Transformation and Oncogenesis        Cellular Response to Infection        Structure and Assembly        Errata

Table of Contents

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Spotlight:

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Articles of Significant Interest Selected from This Issue by the Editors J. Virol. February 2006 80: 1617-1618; [Full Text] [PDF] [Reprints and Permissions]

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Virus-Cell Interactions:

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Envelope Determinants for Dual-Receptor Specificity in Feline Leukemia Virus Subgroup A and T Variants Heather H. Cheng, Maria M. Anderson, F. Claire Hankenson, Lily Johnston, Chitra V. Kotwaliwale, and Julie Overbaugh J. Virol. February 2006 80: 1619-1628; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Function of Small Hydrophobic Proteins of Paramyxovirus Rebecca L. Wilson, Sandra M. Fuentes, Ping Wang, Erica C. Taddeo, Alicia Klatt, Andrew J. Henderson, and Biao He J. Virol. February 2006 80: 1700-1709; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Phosphorylation of the Varicella-Zoster Virus (VZV) Major Transcriptional Regulatory Protein IE62 by the VZV Open Reading Frame 66 Protein Kinase Amie J. Eisfeld, Stephanie E. Turse, Sara A. Jackson, Edwina C. Lerner, and Paul R. Kinchington J. Virol. February 2006 80: 1710-1723; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry Donna M. Tscherne, Christopher T. Jones, Matthew J. Evans, Brett D. Lindenbach, Jane A. McKeating, and Charles M. Rice J. Virol. February 2006 80: 1734-1741; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comprehensive Mapping of Receptor-Functioning Domains in Feline Leukemia Virus Subgroup C Receptor FLVCR1 Jennifer K. Brown, Claire Fung, and Chetankumar S. Tailor J. Virol. February 2006 80: 1742-1751; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Transcriptome Signature of Virulent and Attenuated Pseudorabies Virus-Infected Rodent Brain Christina Paulus, Patricia J. Sollars, Gary E. Pickard, and Lynn W. Enquist J. Virol. February 2006 80: 1773-1786; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Hyperphosphorylation of the Rotavirus NSP5 Protein Is Independent of Serine 67 or NSP2, and the Intrinsic Insolubility of NSP5 Is Regulated by Cellular Phosphatases Adrish Sen, Darin Agresti, and Erich R. Mackow J. Virol. February 2006 80: 1807-1816; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Functional Analysis of Hepatitis C Virus Envelope Proteins, Using a Cell-Cell Fusion Assay Mariko Kobayashi, Michael C. Bennett, Theodore Bercot, and Ila R. Singh J. Virol. February 2006 80: 1817-1825; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Modulation of Cellular Protein Trafficking by Human Immunodeficiency Virus Type 1 Nef: Role of the Acidic Residue in the ExxxLL Motif Scott H. Coleman, Ricardo Madrid, Nanette Van Damme, Richard S. Mitchell, Jerome Bouchet, Cecile Servant, Satish Pillai, Serge Benichou, and John C. Guatelli J. Virol. February 2006 80: 1837-1849; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Arg279Glu Substitution in the Adenovirus Type 11p (Ad11p) Fiber Knob Abolishes EDTA-Resistant Binding to A549 and CHO-CD46 Cells, Converting the Phenotype to That of Ad7p Dan J. Gustafsson, Anna Segerman, Kristina Lindman, Ya-Fang Mei, and Göran Wadell J. Virol. February 2006 80: 1897-1905; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Nuclear Import of Epstein-Barr Virus Nuclear Antigen 1 Mediated by NPI-1 (Importin 5) Is Up- and Down-Regulated by Phosphorylation of the Nuclear Localization Signal for Which Lys379 and Arg380 Are Essential Ryo Kitamura, Toshihiro Sekimoto, Sayuri Ito, Shizuko Harada, Hideo Yamagata, Hisao Masai, Yoshihiro Yoneda, and Kazuo Yanagi J. Virol. February 2006 80: 1979-1991; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Immunodeficiency Virus Fusion to Dendritic Cells Declines as Cells Mature Marielle Cavrois, Jason Neidleman, Jason F. Kreisberg, David Fenard, Christian Callebaut, and Warner C. Greene J. Virol. February 2006 80: 1992-1999; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Identification of Adenovirus Type 5 Genes That Influence Viral Spread T. Subramanian, S. Vijayalingam, and G. Chinnadurai J. Virol. February 2006 80: 2000-2012; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Dual Wavelength Imaging Allows Analysis of Membrane Fusion of Influenza Virus inside Cells Tatsuya Sakai, Masanobu Ohuchi, Masaki Imai, Takafumi Mizuno, Kazunori Kawasaki, Kazumichi Kuroda, and Shohei Yamashina J. Virol. February 2006 80: 2013-2018; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reovirus Induces and Benefits from an Integrated Cellular Stress Response Jennifer A. Smith, Stephen C. Schmechel, Arvind Raghavan, Michelle Abelson, Cavan Reilly, Michael G. Katze, Randal J. Kaufman, Paul R. Bohjanen, and Leslie A. Schiff J. Virol. February 2006 80: 2019-2033; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

cdc2/Cyclin B1-Dependent Phosphorylation of EBNA2 at Ser243 Regulates Its Function in Mitosis Wei Yue, Julia Shackelford, and Joseph S. Pagano J. Virol. February 2006 80: 2045-2050; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Arsenic Counteracts Human Immunodeficiency Virus Type 1 Restriction by Various TRIM5 Orthologues in a Cell Type-Dependent Manner Sarah Sebastian, Elena Sokolskaja, and Jeremy Luban J. Virol. February 2006 80: 2051-2054; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pathogenesis and Immunity:

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Respiratory Viruses Augment the Adhesion of Bacterial Pathogens to Respiratory Epithelium in a Viral Species- and Cell Type-Dependent Manner Vasanthi Avadhanula, Carina A. Rodriguez, John P. DeVincenzo, Yan Wang, Richard J. Webby, Glen C. Ulett, and Elisabeth E. Adderson J. Virol. February 2006 80: 1629-1636; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pulmonary Immunity to Viral Infection: Adenovirus Infection of Lung Dendritic Cells Renders T Cells Nonresponsive to Interleukin-2 Allison T. Thiele, Tina L. Sumpter, Joanna A. Walker, Qi Xu, Cheong-Hee Chang, Robert L. Bacallao, Rajesh Kher, and David S. Wilkes J. Virol. February 2006 80: 1826-1836; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cytotoxic T-Lymphocyte Epitope Vaccination Protects against Human Metapneumovirus Infection and Disease in Mice Karen A. Herd, Suresh Mahalingam, Ian M. Mackay, Michael Nissen, Theo P. Sloots, and Robert W. Tindle J. Virol. February 2006 80: 2034-2044; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

APOBEC3F and APOBEC3G mRNA Levels Do Not Correlate with Human Immunodeficiency Virus Type 1 Plasma Viremia or CD4+ T-Cell Count Soo-Jin Cho, Henning Drechsler, Ryan C. Burke, Max Q. Arens, William Powderly, and Nicholas O. Davidson J. Virol. February 2006 80: 2069-2072; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Genetic Diversity and Evolution:

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Human Immunodeficiency Virus Type 1 env Evolves toward Ancestral States upon Transmission to a New Host Joshua T. Herbeck, David C. Nickle, Gerald H. Learn, Geoffrey S. Gottlieb, Marcel E. Curlin, Laura Heath, and James I. Mullins J. Virol. February 2006 80: 1637-1644; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Vaccines and Antiviral Agents:

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Generation of CD8+ T-Cell Responses by a Recombinant Nonpathogenic Mycobacterium smegmatis Vaccine Vector Expressing Human Immunodeficiency Virus Type 1 Env Mark J. Cayabyab, Avi-Hai Hovav, Tsungda Hsu, Georgia R. Krivulka, Michelle A. Lifton, Darci A. Gorgone, Glenn J. Fennelly, Barton F. Haynes, William R. Jacobs, Jr., and Norman L. Letvin J. Virol. February 2006 80: 1645-1652; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Structure-Function Analysis of the Epitope for 4E10, a Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Florence M. Brunel, Michael B. Zwick, Rosa M. F. Cardoso, Josh D. Nelson, Ian A. Wilson, Dennis R. Burton, and Philip E. Dawson J. Virol. February 2006 80: 1680-1687; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

A Novel Adenovirus Type 6 (Ad6)-Based Hepatitis C Virus Vector That Overcomes Preexisting Anti-Ad5 Immunity and Induces Potent and Broad Cellular Immune Responses in Rhesus Macaques Stefania Capone, Annalisa Meola, Bruno Bruni Ercole, Alessandra Vitelli, Monica Pezzanera, Lionello Ruggeri, Mary Ellen Davies, Rosalba Tafi, Claudia Santini, Alessandra Luzzago, Tong-Ming Fu, Andrew Bett, Stefano Colloca, Riccardo Cortese, Alfredo Nicosia, and Antonella Folgori J. Virol. February 2006 80: 1688-1699; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Rectal Immunization with Rotavirus Virus-Like Particles Induces Systemic and Mucosal Humoral Immune Responses and Protects Mice against Rotavirus Infection Nathalie Parez, Cynthia Fourgeux, Ali Mohamed, Catherine Dubuquoy, Mathieu Pillot, Axelle Dehee, Annie Charpilienne, Didier Poncet, Isabelle Schwartz-Cornil, and Antoine Garbarg-Chenon J. Virol. February 2006 80: 1752-1761; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Multimeric Soluble CD40 Ligand and GITR Ligand as Adjuvants for Human Immunodeficiency Virus DNA Vaccines Geoffrey W. Stone, Suzanne Barzee, Victoria Snarsky, Kristin Kee, Celsa A. Spina, Xiao-Fang Yu, and Richard S. Kornbluth J. Virol. February 2006 80: 1762-1772; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Pol II Fusion Promoter Directs Human Immunodeficiency Virus Type 1-Inducible Coexpression of a Short Hairpin RNA and Protein Hoshang J. Unwalla, Hai-Tang Li, Ingrid Bahner, Ming-Jie Li, Donald Kohn, and John J. Rossi J. Virol. February 2006 80: 1863-1873; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Involvement of Multiple Epitope-Specific Cytotoxic T-Lymphocyte Responses in Vaccine-Based Control of Simian Immunodeficiency Virus Replication in Rhesus Macaques Miki Kawada, Hiroko Igarashi, Akiko Takeda, Tetsuo Tsukamoto, Hiroyuki Yamamoto, Sachi Dohki, Masafumi Takiguchi, and Tetsuro Matano J. Virol. February 2006 80: 1949-1958; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antibody Prophylaxis and Therapy against Nipah Virus Infection in Hamsters V. Guillaume, H. Contamin, P. Loth, I. Grosjean, M. C. Georges Courbot, V. Deubel, R. Buckland, and T. F. Wild J. Virol. February 2006 80: 1972-1978; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Genome Replication and Regulation of Viral Gene Expression:

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Site-Directed Mutagenesis of the Nidovirus Replicative Endoribonuclease NendoU Exerts Pleiotropic Effects on the Arterivirus Life Cycle Clara C. Posthuma, Danny D. Nedialkova, Jessika C. Zevenhoven-Dobbe, Jeroen H. Blokhuis, Alexander E. Gorbalenya, and Eric J. Snijder J. Virol. February 2006 80: 1653-1661; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Poliovirus Protein 3AB Displays Nucleic Acid Chaperone and Helix-Destabilizing Activities Jeffrey J. DeStefano and Oduyebo Titilope J. Virol. February 2006 80: 1662-1671; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of the Role of Very Late Expression Factor 1 in Baculovirus Capsid Structure and DNA Processing Adam L. Vanarsdall, Kazuhiro Okano, and George F. Rohrmann J. Virol. February 2006 80: 1724-1733; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Importin-ß Family Members Mediate Alpharetrovirus Gag Nuclear Entry via Interactions with Matrix and Nucleocapsid Kristin L. Butterfield-Gerson, Lisa Z. Scheifele, Eileen P. Ryan, Anita K. Hopper, and Leslie J. Parent J. Virol. February 2006 80: 1798-1806; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Transient and Stable Knockdown of the Integrase Cofactor LEDGF/p75 Reveals Its Role in the Replication Cycle of Human Immunodeficiency Virus Linos Vandekerckhove, Frauke Christ, Bénédicte Van Maele, Jan De Rijck, Rik Gijsbers, Chris Van den Haute, Myriam Witvrouw, and Zeger Debyser J. Virol. February 2006 80: 1886-1896; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Insights into Gene Expression Changes Impacting B-Cell Transformation: Cross-Species Microarray Analysis of Bovine Leukemia Virus Tax-Responsive Genes in Ovine B Cells Pavel Klener, Maud Szynal, Yvette Cleuter, Makram Merimi, Hugues Duvillier, Françoise Lallemand, Claude Bagnis, Philip Griebel, Christos Sotiriou, Arsène Burny, Philippe Martiat, and Anne Van den Broeke J. Virol. February 2006 80: 1922-1938; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Immunodeficiency Virus Type 1 Incorporated with Fusion Proteins Consisting of Integrase and the Designed Polydactyl Zinc Finger Protein E2C Can Bias Integration of Viral DNA into a Predetermined Chromosomal Region in Human Cells Wenjie Tan, Zheng Dong, Thomas A. Wilkinson, Carlos F. Barbas, III, and Samson A. Chow J. Virol. February 2006 80: 1939-1948; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of Spliced Gammaherpesvirus 68 LANA and v-Cyclin Transcripts and Analysis of Their Expression In Vivo during Latent Infection Robert D. Allen, III, Shelley Dickerson, and Samuel H. Speck J. Virol. February 2006 80: 2055-2062; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Deacetylation of the Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Enhancer and a Decrease in LAT Abundance Precede an Increase in ICP0 Transcriptional Permissiveness at Early Times Postexplant Antonio L. Amelio, Nicole V. Giordani, Nicole J. Kubat, Jerome E. O'Neil, and David C. Bloom J. Virol. February 2006 80: 2063-2068; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Gene Delivery:

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Efficient Site-Specific Integration of Large Transgenes by an Enhanced Herpes Simplex Virus/Adeno-Associated Virus Hybrid Amplicon Vector Qiang Liu, Claudio F. Perez, and Yaming Wang J. Virol. February 2006 80: 1672-1679; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Scalable Generation of High-Titer Recombinant Adeno-Associated Virus Type 5 in Insect Cells Masashi Urabe, Takayo Nakakura, Ke-Qin Xin, Yoko Obara, Hiroaki Mizukami, Akihiro Kume, Robert M. Kotin, and Keiya Ozawa J. Virol. February 2006 80: 1874-1885; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Protection of Mice and Poultry from Lethal H5N1 Avian Influenza Virus through Adenovirus-Based Immunization Wentao Gao, Adam C. Soloff, Xiuhua Lu, Angela Montecalvo, Doan C. Nguyen, Yumi Matsuoka, Paul D. Robbins, David E. Swayne, Ruben O. Donis, Jacqueline M. Katz, Simon M. Barratt-Boyes, and Andrea Gambotto J. Virol. February 2006 80: 1959-1964; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Transformation and Oncogenesis:

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Regulation of Human Papillomavirus Type 16 E7 Activity through Direct Protein Interaction with the E2 Transcriptional Activator Noor Gammoh, Helena Sterlinko Grm, Paola Massimi, and Lawrence Banks J. Virol. February 2006 80: 1787-1797; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Cellular Response to Infection:

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CD4-Specific Transgenic Expression of Human Cyclin T1 Markedly Increases Human Immunodeficiency Virus Type 1 (HIV-1) Production by CD4+ T Lymphocytes and Myeloid Cells in Mice Transgenic for a Provirus Encoding a Monocyte-Tropic HIV-1 Isolate Jinglin Sun, Timothy Soos, Vineet N. KewalRamani, Kristin Osiecki, Jian Hua Zheng, Laurie Falkin, Laura Santambrogio, Dan R. Littman, and Harris Goldstein J. Virol. February 2006 80: 1850-1862; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Leader Proteinase of Foot-and-Mouth Disease Virus Inhibits the Induction of Beta Interferon mRNA and Blocks the Host Innate Immune Response Teresa de los Santos, Sonia de Avila Botton, Rudi Weiblen, and Marvin J. Grubman J. Virol. February 2006 80: 1906-1914; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Structure and Assembly:

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Core Protein of Pestiviruses Is Processed at the C Terminus by Signal Peptide Peptidase Manuela Heimann, Gleyder Roman Sosa, Bruno Martoglio, Heinz-Jürgen Thiel, and Till Rümenapf J. Virol. February 2006 80: 1915-1921; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Dependence of the Encapsidation Function of the Adenovirus L1 52/55-Kilodalton Protein on Its Ability To Bind the Packaging Sequence Pilar Perez-Romero, Kurt E. Gustin, and Michael J. Imperiale J. Virol. February 2006 80: 1965-1971; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Errata:

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Envelope Is a Major Viral Determinant of the Distinct In Vitro Cellular Transformation Tropism of Human T-Cell Leukemia Virus Type 1 (HTLV-1) and HTLV-2 Li Xie and Patrick L. Green J. Virol. February 2006 80: 2073 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.