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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2006 80: 11897-11898. [Full Text] [PDF] FREE [Reprints and Permissions]  

Vaccines and Antiviral Agents:

Ke-Qin Xin, Hiroaki Mizukami, Masashi Urabe, Yoshihiko Toda, Kaori Shinoda, Atsushi Yoshida, Kenji Oomura, Yoshitsugu Kojima, Motohide Ichino, Dennis Klinman, Keiya Ozawa, and Kenji Okuda

Induction of Robust Immune Responses against Human Immunodeficiency Virus Is Supported by the Inherent Tropism of Adeno-Associated Virus Type 5 for Dendritic Cells
J. Virol. 2006 80: 11899-11910. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeremy C. Jones, Elizabeth A. Turpin, Hermann Bultmann, Curtis R. Brandt, and Stacey Schultz-Cherry

Inhibition of Influenza Virus Infection by a Novel Antiviral Peptide That Targets Viral Attachment to Cells
J. Virol. 2006 80: 11960-11967. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jinyan Liu, Bonnie A. Ewald, Diana M. Lynch, Anjali Nanda, Shawn M. Sumida, and Dan H. Barouch

Modulation of DNA Vaccine-Elicited CD8⁺ T-Lymphocyte Epitope Immunodominance Hierarchies
J. Virol. 2006 80: 11991-11997. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anna R. Thorner, Angelique A. C. Lemckert, Jaap Goudsmit, Diana M. Lynch, Bonnie A. Ewald, Matthew Denholtz, Menzo J. E. Havenga, and Dan H. Barouch

Immunogenicity of Heterologous Recombinant Adenovirus Prime-Boost Vaccine Regimens Is Enhanced by Circumventing Vector Cross-Reactivity
J. Virol. 2006 80: 12009-12016. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jing Zhou, Chin Ho Chen, and Christopher Aiken

Human Immunodeficiency Virus Type 1 Resistance to the Small Molecule Maturation Inhibitor 3-O-(3',3'-Dimethylsuccinyl)-Betulinic Acid Is Conferred by a Variety of Single Amino Acid Substitutions at the CA-SP1 Cleavage Site in Gag
J. Virol. 2006 80: 12095-12101. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Theodore Oliphant, Grant E. Nybakken, Michael Engle, Qing Xu, Christopher A. Nelson, Soila Sukupolvi-Petty, Anantha Marri, Bat-El Lachmi, Udy Olshevsky, Daved H. Fremont, Theodore C. Pierson, and Michael S. Diamond

Antibody Recognition and Neutralization Determinants on Domains I and II of West Nile Virus Envelope Protein
J. Virol. 2006 80: 12149-12159. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Dirk Jochmans, Jérôme Deval, Bart Kesteleyn, Herwig Van Marck, Eva Bettens, Inky De Baere, Pascale Dehertogh, Tania Ivens, Marcia Van Ginderen, Bertrand Van Schoubroeck, Maryam Ehteshami, Piet Wigerinck, Matthias Götte, and Kurt Hertogs

Indolopyridones Inhibit Human Immunodeficiency Virus Reverse Transcriptase with a Novel Mechanism of Action
J. Virol. 2006 80: 12283-12292. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bruce A. Mungall, Deborah Middleton, Gary Crameri, John Bingham, Kim Halpin, Gail Russell, Diane Green, Jennifer McEachern, L. Ian Pritchard, Bryan T. Eaton, Lin-Fa Wang, Katharine N. Bossart, and Christopher C. Broder

Feline Model of Acute Nipah Virus Infection and Protection with a Soluble Glycoprotein-Based Subunit Vaccine
J. Virol. 2006 80: 12293-12302. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Structure and Assembly:

Tao Deng, Othmar G. Engelhardt, Benjamin Thomas, Alexandre V. Akoulitchev, George G. Brownlee, and Ervin Fodor

Role of Ran Binding Protein 5 in Nuclear Import and Assembly of the Influenza Virus RNA Polymerase Complex
J. Virol. 2006 80: 11911-11919. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susan D. Saban, Mariena Silvestry, Glen R. Nemerow, and Phoebe L. Stewart

Visualization of -Helices in a 6-Ångstrom Resolution Cryoelectron Microscopy Structure of Adenovirus Allows Refinement of Capsid Protein Assignments
J. Virol. 2006 80: 12049-12059. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Michael J. Ciancanelli and Christopher F. Basler

Mutation of YMYL in the Nipah Virus Matrix Protein Abrogates Budding and Alters Subcellular Localization
J. Virol. 2006 80: 12070-12078. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joy I-Hsuan Lee, G. W. Gant Luxton, and Gregory Allan Smith

Identification of an Essential Domain in the Herpesvirus VP1/2 Tegument Protein: the Carboxy Terminus Directs Incorporation into Capsid Assemblons
J. Virol. 2006 80: 12086-12094. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Klaus K. Orlinger, Verena M. Hoenninger, Regina M. Kofler, and Christian W. Mandl

Construction and Mutagenesis of an Artificial Bicistronic Tick-Borne Encephalitis Virus Genome Reveals an Essential Function of the Second Transmembrane Region of Protein E in Flavivirus Assembly
J. Virol. 2006 80: 12197-12208. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Danielle K. Reese, Gretchen Meinke, Anuradha Kumar, Stephanie Moine, Kathleen Chen, James L. Sudmeier, William Bachovchin, Andrew Bohm, and Peter A. Bullock

Analyses of the Interaction between the Origin Binding Domain from Simian Virus 40 T Antigen and Single-Stranded DNA Provide Insights into DNA Unwinding and Initiation of DNA Replication
J. Virol. 2006 80: 12248-12259. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carolina Epifano, Jacomine Krijnse-Locker, María L. Salas, Javier M. Rodríguez, and José Salas

The African Swine Fever Virus Nonstructural Protein pB602L Is Required for Formation of the Icosahedral Capsid of the Virus Particle
J. Virol. 2006 80: 12260-12270. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lan Zhang, Kartik Chandran, Max L. Nibert, and Stephen C. Harrison

Reovirus µ1 Structural Rearrangements That Mediate Membrane Penetration
J. Virol. 2006 80: 12367-12376. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elizabeth A. Hewat and Dieter Blaas

Nonneutralizing Human Rhinovirus Serotype 2-Specific Monoclonal Antibody 2G2 Attaches to the Region That Undergoes the Most Dramatic Changes upon Release of the Viral RNA
J. Virol. 2006 80: 12398-12401. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Genome Replication and Regulation of Viral Gene Expression:

David J. Garfinkel, Karen M. Stefanisko, Katherine M. Nyswaner, Sharon P. Moore, Jangsuk Oh, and Stephen H. Hughes

Retrotransposon Suicide: Formation of Ty1 Circles and Autointegration via a Central DNA Flap
J. Virol. 2006 80: 11920-11934. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Matthieu Blanchet and Camille Sureau

Analysis of the Cytosolic Domains of the Hepatitis B Virus Envelope Proteins for Their Function in Viral Particle Assembly and Infectivity
J. Virol. 2006 80: 11935-11945. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vladimir Majerciak, Koji Yamanegi, and Zhi-Ming Zheng

Gene Structure and Expression of Kaposi's Sarcoma-Associated Herpesvirus ORF56, ORF57, ORF58, and ORF59
J. Virol. 2006 80: 11968-11981. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joel Rovnak and Sandra L. Quackenbush

Walleye Dermal Sarcoma Virus Retroviral Cyclin Directly Contacts TAF9
J. Virol. 2006 80: 12041-12048. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kate Manley, Bethany A. O'Hara, Gretchen V. Gee, Carl P. Simkevich, John M. Sedivy, and Walter J. Atwood

NFAT4 Is Required for JC Virus Infection of Glial Cells
J. Virol. 2006 80: 12079-12085. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yan Wang, Qiyi Tang, Gerd G. Maul, and Yan Yuan

Kaposi's Sarcoma-Associated Herpesvirus ori-Lyt-Dependent DNA Replication: Dual Role of Replication and Transcription Activator
J. Virol. 2006 80: 12171-12186. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fan Xiu Zhu, Xiaojuan Li, Fuchun Zhou, Shou-Jiang Gao, and Yan Yuan

Functional Characterization of Kaposi's Sarcoma-Associated Herpesvirus ORF45 by Bacterial Artificial Chromosome-Based Mutagenesis
J. Virol. 2006 80: 12187-12196. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jennie G. Jacobson, Kui Yang, Joel D. Baines, and Fred L. Homa

Linker Insertion Mutations in the Herpes Simplex Virus Type 1 UL28 Gene: Effects on UL28 Interaction with UL15 and UL33 and Identification of a Second-Site Mutation in the UL15 Gene That Suppresses a Lethal UL28 Mutation
J. Virol. 2006 80: 12312-12323. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rafal Wierzchoslawski, Anna Urbanowicz, Aleksandra Dzianott, Marek Figlerowicz, and Jozef J. Bujarski

Characterization of a Novel 5' Subgenomic RNA3a Derived from RNA3 of Brome Mosaic Bromovirus
J. Virol. 2006 80: 12357-12366. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Meike Hass, Martina Westerkofsky, Stefanie Müller, Beate Becker-Ziaja, Carola Busch, and Stephan Günther

Mutational Analysis of the Lassa Virus Promoter
J. Virol. 2006 80: 12414-12419. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pathogenesis and Immunity:

Jason W. Upton and Samuel H. Speck

Evidence for CDK-Dependent and CDK-Independent Functions of the Murine Gammaherpesvirus 68 v-Cyclin
J. Virol. 2006 80: 11946-11959. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Arnaud Florins, Nicolas Gillet, Becca Asquith, Christophe Debacq, Geneviève Jean, Isabelle Schwartz-Cornil, Michel Bonneau, Arsène Burny, Michal Reichert, Richard Kettmann, and Luc Willems

Spleen-Dependent Turnover of CD11b Peripheral Blood B Lymphocytes in Bovine Leukemia Virus-Infected Sheep
J. Virol. 2006 80: 11998-12008. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Edwin R. Manuel, William A. Charini, Pritha Sen, Fred W. Peyerl, Marcelo J. Kuroda, Jörn E. Schmitz, Patrick Autissier, Dennis A. Sheeter, Bruce E. Torbett, and Norman L. Letvin

Contribution of T-Cell Receptor Repertoire Breadth to the Dominance of Epitope-Specific CD8⁺ T-Lymphocyte Responses
J. Virol. 2006 80: 12032-12040. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elizabeth M. Sitati and Michael S. Diamond

CD4⁺ T-Cell Responses Are Required for Clearance of West Nile Virus from the Central Nervous System
J. Virol. 2006 80: 12060-12069. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gregory P. Owens, Andrew J. Shearer, Xiaoli Yu, Alanna M. Ritchie, Kathryne M. Keays, Jeffrey L. Bennett, Donald H. Gilden, and Mark P. Burgoon

Screening Random Peptide Libraries with Subacute Sclerosing Panencephalitis Brain-Derived Recombinant Antibodies Identifies Multiple Epitopes in the C-Terminal Region of the Measles Virus Nucleocapsid Protein
J. Virol. 2006 80: 12121-12130. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

James H. McLinden, Thomas M. Kaufman, Jinhua Xiang, Qing Chang, Donna Klinzman, Alfred M. Engel, Georg Hess, Urban Schmidt, Michael Houghton, and Jack T. Stapleton

Characterization of an Immunodominant Antigenic Site on GB Virus C Glycoprotein E2 That Is Involved in Cell Binding
J. Virol. 2006 80: 12131-12140. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mikhail V. Ovanesov, Christian Sauder, Steven A. Rubin, Jürgen Richt, Avindra Nath, Kathryn M. Carbone, and Mikhail V. Pletnikov

Activation of Microglia by Borna Disease Virus Infection: In Vitro Study
J. Virol. 2006 80: 12141-12148. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christina J. Sigurdson, Giuseppe Manco, Petra Schwarz, Pawel Liberski, Edward A. Hoover, Simone Hornemann, Magdalini Polymenidou, Michael W. Miller, Markus Glatzel, and Adriano Aguzzi

Strain Fidelity of Chronic Wasting Disease upon Murine Adaptation
J. Virol. 2006 80: 12303-12311. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Myung Guk Han, Doo-Sung Cheon, Xuming Zhang, and Linda J. Saif

Cross-Protection against a Human Enteric Coronavirus and a Virulent Bovine Enteric Coronavirus in Gnotobiotic Calves
J. Virol. 2006 80: 12350-12356. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kelly L. Warfield, Sarah E. Blutt, Sue E. Crawford, Gagandeep Kang, and Margaret E. Conner

Rotavirus Infection Enhances Lipopolysaccharide-Induced Intussusception in a Mouse Model
J. Virol. 2006 80: 12377-12386. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andres F. Mejia, Timothy D. Culp, Nancy M. Cladel, Karla K. Balogh, Lynn R. Budgeon, Christopher B. Buck, and Neil D. Christensen

Preclinical Model To Test Human Papillomavirus Virus (HPV) Capsid Vaccines In Vivo Using Infectious HPV/Cottontail Rabbit Papillomavirus Chimeric Papillomavirus Particles
J. Virol. 2006 80: 12393-12397. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rui Soares, Russell Foxall, Adriana Albuquerque, Catarina Cortesão, Miguel Garcia, Rui M. M. Victorino, and Ana E. Sousa

Increased Frequency of Circulating CCR5⁺ CD4⁺ T Cells in Human Immunodeficiency Virus Type 2 Infection
J. Virol. 2006 80: 12425-12429. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Virus-Cell Interactions:

Wu Ou and Jonathan Silver

Stoichiometry of Murine Leukemia Virus Envelope Protein-Mediated Fusion and Its Neutralization
J. Virol. 2006 80: 11982-11990. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carlos Ros, Marco Gerber, and Christoph Kempf

Conformational Changes in the VP1-Unique Region of Native Human Parvovirus B19 Lead to Exposure of Internal Sequences That Play a Role in Virus Neutralization and Infectivity
J. Virol. 2006 80: 12017-12024. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Masumi Takano-Maruyama, Yoshiro Ohara, Kunihiko Asakura, and Takako Okuwa

Theiler's Murine Encephalomyelitis Virus Leader Protein Amino Acid Residue 57 Regulates Subgroup-Specific Virus Growth on BHK-21 Cells
J. Virol. 2006 80: 12025-12031. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brian P. Doehle, Hal P. Bogerd, Heather L. Wiegand, Nolwenn Jouvenet, Paul D. Bieniasz, Eric Hunter, and Bryan R. Cullen

The Betaretrovirus Mason-Pfizer Monkey Virus Selectively Excludes Simian APOBEC3G from Virion Particles
J. Virol. 2006 80: 12102-12108. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sebastian Tuve, Hongjie Wang, Carol Ware, Ying Liu, Anuj Gaggar, Kathrin Bernt, Dmitry Shayakhmetov, ZongYi Li, Robert Strauss, Daniel Stone, and André Lieber

A New Group B Adenovirus Receptor Is Expressed at High Levels on Human Stem and Tumor Cells
J. Virol. 2006 80: 12109-12120. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elisa H. Fleming, Andrey A. Kolokoltsov, Robert A. Davey, Joan E. Nichols, and Norbert J. Roberts, Jr.

Respiratory Syncytial Virus F Envelope Protein Associates with Lipid Rafts without a Requirement for Other Virus Proteins
J. Virol. 2006 80: 12160-12170. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Benjamin Galen, Natalia Cheshenko, Ana Tuyama, Bharat Ramratnam, and Betsy C. Herold

Access to Nectin Favors Herpes Simplex Virus Infection at the Apical Surface of Polarized Human Epithelial Cells
J. Virol. 2006 80: 12209-12218. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeremy A. Kroemer and Bruce A. Webb

Divergences in Protein Activity and Cellular Localization within the Campoletis sonorensis Ichnovirus Vankyrin Family
J. Virol. 2006 80: 12219-12228. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Iñigo Narvaiza, Oscar Aparicio, María Vera, Nerea Razquin, Sergia Bortolanza, Jesús Prieto, and Puri Fortes

Effect of Adenovirus-Mediated RNA Interference on Endogenous MicroRNAs in a Mouse Model of Multidrug Resistance Protein 2 Gene Silencing
J. Virol. 2006 80: 12236-12247. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Prabhat K. Singhal, P. Rajendra Kumar, Malireddi R. K. Subba Rao, and Sundarasamy Mahalingam

Nuclear Export of Simian Immunodeficiency Virus Vpx Protein
J. Virol. 2006 80: 12271-12282. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andrea Bugarcic and John A. Taylor

Rotavirus Nonstructural Glycoprotein NSP4 Is Secreted from the Apical Surfaces of Polarized Epithelial Cells
J. Virol. 2006 80: 12343-12349. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shih-Heng Chen, Hui-Wen Yao, Wen-Yen Huang, Kuei-Sen Hsu, Huan-Yao Lei, Ai-Li Shiau, and Shun-Hua Chen

Efficient Reactivation of Latent Herpes Simplex Virus from Mouse Central Nervous System Tissues
J. Virol. 2006 80: 12387-12392. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jose-Andres Mendoza, Yves Jacob, Patricia Cassonnet, and Michel Favre

Human Papillomavirus Type 5 E6 Oncoprotein Represses the Transforming Growth Factor ß Signaling Pathway by Binding to SMAD3
J. Virol. 2006 80: 12420-12424. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Genetic Diversity and Evolution:

Gang Zhang, Dany Shoham, David Gilichinsky, Sergei Davydov, John D. Castello, and Scott O. Rogers

Evidence of Influenza A Virus RNA in Siberian Lake Ice
J. Virol. 2006 80: 12229-12235. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sayandip Mukherjee, Hui-Ling Rose Lee, Yacov Ron, and Joseph P. Dougherty

Proviral Progeny of Heterodimeric Virions Reveal a High Crossover Rate for Human Immunodeficiency Virus Type 2
J. Virol. 2006 80: 12402-12407. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gene Delivery:

Jiali Li, Sonya Lad, Guang Yang, Yunping Luo, Milena Iacobelli-Martinez, F. James Primus, Ralph A. Reisfeld, and Erguang Li

Adenovirus Fiber Shaft Contains a Trimerization Element That Supports Peptide Fusion for Targeted Gene Delivery
J. Virol. 2006 80: 12324-12331. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cellular Response to Infection:

Akihiko Komuro and Curt M. Horvath

RNA- and Virus-Independent Inhibition of Antiviral Signaling by RNA Helicase LGP2
J. Virol. 2006 80: 12332-12342. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jenny O'Nions, Abigail Turner, Richard Craig, and Martin J. Allday

Epstein-Barr Virus Selectively Deregulates DNA Damage Responses in Normal B Cells but Has No Detectable Effect on Regulation of the Tumor Suppressor p53
J. Virol. 2006 80: 12408-12413. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Peter J. Alff, Irina N. Gavrilovskaya, Elena Gorbunova, Karen Endriss, YuSon Chong, Erika Geimonen, Nandini Sen, Nancy C. Reich, and Erich R. Mackow

The Pathogenic NY-1 Hantavirus G1 Cytoplasmic Tail Inhibits RIG-1- and TBK-1-Directed Interferon Responses
J. Virol. 2006 80: 12430. [Full Text] [PDF] [Reprints and Permissions]  

Heather H. Cheng, Maria M. Anderson, F. Claire Hankenson, Lily Johnston, Chitra V. Kotwaliwale, and Julie Overbaugh

Envelope Determinants for Dual-Receptor Specificity in Feline Leukemia Virus Subgroup A and T Variants
J. Virol. 2006 80: 12431. [Full Text] [PDF] [Reprints and Permissions]  

Author's Corrections:

Preety M. Sharma, Gaurav Gupta, Abhay Vats, Ron Shapiro, and Parmjeet Randhawa

Phylogenetic Analysis of Polyomavirus BK Sequences
J. Virol. 2006 80: 12432. [Full Text] [PDF] [Reprints and Permissions]  

Jamie Ashby, Emmanuel Boutant, Mark Seemanpillai, Anna Groner, Adrian Sambade, Christophe Ritzenthaler, and Manfred Heinlein

Tobacco Mosaic Virus Movement Protein Functions as a Structural Microtubule-Associated Protein
J. Virol. 2006 80: 12433. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.