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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2006 80: 9927. [Full Text] [PDF] FREE [Reprints and Permissions]  

Genetic Diversity and Evolution:

Laura A. Shackelton, Andrew Rambaut, Oliver G. Pybus, and Edward C. Holmes

JC Virus Evolution and Its Association with Human Populations
J. Virol. 2006 80: 9928-9933. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Thomas Preuss, Nicole Fischer, Klaus Boller, and Ralf R. Tönjes

Isolation and Characterization of an Infectious Replication-Competent Molecular Clone of Ecotropic Porcine Endogenous Retrovirus Class C
J. Virol. 2006 80: 10258-10261. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Transformation and Oncogenesis:

Elke Heck, Ute Friedrich, Michaela U. Gack, Doris Lengenfelder, Monika Schmidt, Ingrid Müller-Fleckenstein, Bernhard Fleckenstein, Armin Ensser, and Brigitte Biesinger

Growth Transformation of Human T Cells by Herpesvirus Saimiri Requires Multiple Tip-Lck Interaction Motifs
J. Virol. 2006 80: 9934-9942. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pathogenesis and Immunity:

Navkiran Gill, Philip M. Deacon, Brian Lichty, Karen L. Mossman, and Ali A. Ashkar

Induction of Innate Immunity against Herpes Simplex Virus Type 2 Infection via Local Delivery of Toll-Like Receptor Ligands Correlates with Beta Interferon Production
J. Virol. 2006 80: 9943-9950. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Natalia Fernandez-Borges, Alejandro Brun, J. Lindsay Whitton, Beatriz Parra, Fayna Diaz-San Segundo, Francisco J. Salguero, Juan M. Torres, and Fernando Rodriguez

DNA Vaccination Can Break Immunological Tolerance to PrP in Wild-Type Mice and Attenuates Prion Disease after Intracerebral Challenge
J. Virol. 2006 80: 9970-9976. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Melissa M. Herbst-Kralovetz and Richard B. Pyles

Quantification of Poly(I:C)-Mediated Protection against Genital Herpes Simplex Virus Type 2 Infection
J. Virol. 2006 80: 9988-9997. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jie Tang, Mariam Murtadha, Matthias Schnell, Laurence C. Eisenlohr, Jay Hooper, and Phyllis Flomenberg

Human T-Cell Responses to Vaccinia Virus Envelope Proteins
J. Virol. 2006 80: 10010-10020. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

W. W. Shanaka I. Rodrigo, Xia Jin, Shanley D. Blackley, Robert C. Rose, and Jacob J. Schlesinger

Differential Enhancement of Dengue Virus Immune Complex Infectivity Mediated by Signaling-Competent and Signaling-Incompetent Human FcRIA (CD64) or FcRIIA (CD32)
J. Virol. 2006 80: 10128-10138. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John J. Zaunders, Susanna Ip, Mee Ling Munier, Daniel E. Kaufmann, Kazuo Suzuki, Choechoe Brereton, Sarah C. Sasson, Nabila Seddiki, Kersten Koelsch, Alan Landay, Pat Grey, Robert Finlayson, John Kaldor, Eric S. Rosenberg, Bruce D. Walker, Barbara Fazekas de St. Groth, David A. Cooper, Anthony D. Kelleher on Behalf of the PHAEDRA Study Team

Infection of CD127⁺ (Interleukin-7 Receptor⁺) CD4⁺ Cells and Overexpression of CTLA-4 Are Linked to Loss of Antigen-Specific CD4 T Cells during Primary Human Immunodeficiency Virus Type 1 Infection
J. Virol. 2006 80: 10162-10172. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laurent Gros, Mireia Pelegrin, Marc Plays, and Marc Piechaczyk

Efficient Mother-to-Child Transfer of Antiretroviral Immunity in the Context of Preclinical Monoclonal Antibody-Based Immunotherapy
J. Virol. 2006 80: 10191-10200. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

R. Thiéry, J. Cozien, J. Cabon, F. Lamour, M. Baud, and A. Schneemann

Induction of a Protective Immune Response against Viral Nervous Necrosis in the European Sea Bass Dicentrarchus labrax by Using Betanodavirus Virus-Like Particles
J. Virol. 2006 80: 10201-10207. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sujan Shresta, Kristin L. Sharar, Daniil M. Prigozhin, P. Robert Beatty, and Eva Harris

Murine Model for Dengue Virus-Induced Lethal Disease with Increased Vascular Permeability
J. Virol. 2006 80: 10208-10217. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pierre Delobel, Marie-Thérèse Nugeyre, Michelle Cazabat, Karine Sandres-Sauné, Christophe Pasquier, Lise Cuzin, Bruno Marchou, Patrice Massip, Rémi Cheynier, Françoise Barré-Sinoussi, Jacques Izopet, and Nicole Israël

Naïve T-Cell Depletion Related to Infection by X4 Human Immunodeficiency Virus Type 1 in Poor Immunological Responders to Highly Active Antiretroviral Therapy
J. Virol. 2006 80: 10229-10236. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Gavin C. Bowick, Susan M. Fennewald, Barry L. Elsom, Judith F. Aronson, Bruce A. Luxon, David G. Gorenstein, and Norbert K. Herzog

Differential Signaling Networks Induced by Mild and Lethal Hemorrhagic Fever Virus Infections
J. Virol. 2006 80: 10248-10252. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Simon C. Weli, Courtney A. Scott, Christopher A. Ward, and Alan C. Jackson

Rabies Virus Infection of Primary Neuronal Cultures and Adult Mice: Failure To Demonstrate Evidence of Excitotoxicity
J. Virol. 2006 80: 10270-10273. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Virus-Cell Interactions:

Mark Shlapobersky, Rebecca Sanders, Charles Clark, and Deborah H. Spector

Repression of HMGA2 Gene Expression by Human Cytomegalovirus Involves the IE2 86-Kilodalton Protein and Is Necessary for Efficient Viral Replication and Inhibition of Cyclin A Transcription
J. Virol. 2006 80: 9951-9961. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Matthew Reeves, Jane Murphy, Richard Greaves, Jennifer Fairley, Alex Brehm, and John Sinclair

Autorepression of the Human Cytomegalovirus Major Immediate-Early Promoter/Enhancer at Late Times of Infection Is Mediated by the Recruitment of Chromatin Remodeling Enzymes by IE86
J. Virol. 2006 80: 9998-10009. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laura A. Adang, Christopher H. Parsons, and Dean H. Kedes

Asynchronous Progression through the Lytic Cascade and Variations in Intracellular Viral Loads Revealed by High-Throughput Single-Cell Analysis of Kaposi's Sarcoma-Associated Herpesvirus Infection
J. Virol. 2006 80: 10073-10082. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Masayuki Shimojima, Ayato Takada, Hideki Ebihara, Gabriele Neumann, Kouki Fujioka, Tatsuro Irimura, Steven Jones, Heinz Feldmann, and Yoshihiro Kawaoka

Tyro3 Family-Mediated Cell Entry of Ebola and Marburg Viruses
J. Virol. 2006 80: 10109-10116. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Adrienne Chen, Bo Zhao, Elliott Kieff, Jon C. Aster, and Fred Wang

EBNA-3B- and EBNA-3C-Regulated Cellular Genes in Epstein-Barr Virus-Immortalized Lymphoblastoid Cell Lines
J. Virol. 2006 80: 10139-10150. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andru Tomoiu, Annie Gravel, Robert M. Tanguay, and Louis Flamand

Functional Interaction between Human Herpesvirus 6 Immediate-Early 2 Protein and Ubiquitin-Conjugating Enzyme 9 in the Absence of Sumoylation
J. Virol. 2006 80: 10218-10228. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nathalie Arhel, Sandie Munier, Philippe Souque, Karine Mollier, and Pierre Charneau

Nuclear Import Defect of Human Immunodeficiency Virus Type 1 DNA Flap Mutants Is Not Dependent on the Viral Strain or Target Cell Type
J. Virol. 2006 80: 10262-10269. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Genome Replication and Regulation of Viral Gene Expression:

Shailly Tomar, Richard W. Hardy, Janet L. Smith, and Richard J. Kuhn

Catalytic Core of Alphavirus Nonstructural Protein nsP4 Possesses Terminal Adenylyltransferase Activity
J. Virol. 2006 80: 9962-9969. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Janneke Verhagen, Michelle Donnelly, and Gillian Elliott

Characterization of a Novel Transferable CRM-1-Independent Nuclear Export Signal in a Herpesvirus Tegument Protein That Shuttles between the Nucleus and Cytoplasm
J. Virol. 2006 80: 10021-10035. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Soo-Jin Jeong, Hanxin Lu, Won-Kyung Cho, Hyeon Ung Park, Cynthia Pise-Masison, and John N. Brady

Coactivator-Associated Arginine Methyltransferase 1 Enhances Transcriptional Activity of the Human T-Cell Lymphotropic Virus Type 1 Long Terminal Repeat through Direct Interaction with Tax
J. Virol. 2006 80: 10036-10044. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ruizhong Shen, Aurélie M. Rakotondrafara, and W. Allen Miller

trans Regulation of Cap-Independent Translation by a Viral Subgenomic RNA
J. Virol. 2006 80: 10045-10054. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ayumi Kudoh, Tohru Daikoku, Yukio Ishimi, Yasushi Kawaguchi, Noriko Shirata, Satoko Iwahori, Hiroki Isomura, and Tatsuya Tsurumi

Phosphorylation of MCM4 at Sites Inactivating DNA Helicase Activity of the MCM4-MCM6-MCM7 Complex during Epstein-Barr Virus Productive Replication
J. Virol. 2006 80: 10064-10072. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Padmanaban Annamalai and A. L. N. Rao

Packaging of Brome Mosaic Virus Subgenomic RNA Is Functionally Coupled to Replication-Dependent Transcription and Translation of Coat Protein
J. Virol. 2006 80: 10096-10108. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephanie J. Child, Laura K. Hanson, Crystal E. Brown, Deanna M. Janzen, and Adam P. Geballe

Double-Stranded RNA Binding by a Heterodimeric Complex of Murine Cytomegalovirus m142 and m143 Proteins
J. Virol. 2006 80: 10173-10180. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ralitsa S. Valchanova, Marcus Picard-Maureau, Matthias Budt, and Wolfram Brune

Murine Cytomegalovirus m142 and m143 Are both Required To Block Protein Kinase R-Mediated Shutdown of Protein Synthesis
J. Virol. 2006 80: 10181-10190. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bruno Sainz, Jr. and Francis V. Chisari

Production of Infectious Hepatitis C Virus by Well-Differentiated, Growth-Arrested Human Hepatoma-Derived Cells
J. Virol. 2006 80: 10253-10257. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Peter Lischka, Claudia Rauh, Regina Mueller, and Thomas Stamminger

Human Cytomegalovirus UL84 Protein Contains Two Nuclear Export Signals and Shuttles between the Nucleus and the Cytoplasm
J. Virol. 2006 80: 10274-10280. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jangsuk Oh, Kevin W. Chang, W. Gregory Alvord, and Stephen H. Hughes

Alternate Polypurine Tracts Affect Rous Sarcoma Virus Integration In Vivo
J. Virol. 2006 80: 10281-10284. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Cellular Response to Infection:

Liang Deng, Peihong Dai, Wanhong Ding, Richard D. Granstein, and Stewart Shuman

Vaccinia Virus Infection Attenuates Innate Immune Responses and Antigen Presentation by Epidermal Dendritic Cells
J. Virol. 2006 80: 9977-9987. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Adrian Valli, Ana Montserrat Martín-Hernández, Juan José López-Moya, and Juan Antonio García

RNA Silencing Suppression by a Second Copy of the P1 Serine Protease of Cucumber Vein Yellowing Ipomovirus, a Member of the Family Potyviridae That Lacks the Cysteine Protease HCPro
J. Virol. 2006 80: 10055-10063. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Jeffrey O. Langland, John C. Kash, Victoria Carter, Matthew J. Thomas, Michael G. Katze, and Bertram L. Jacobs

Suppression of Proinflammatory Signal Transduction and Gene Expression by the Dual Nucleic Acid Binding Domains of the Vaccinia Virus E3L Proteins
J. Virol. 2006 80: 10083-10095. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Structure and Assembly:

Aparna Mukhopadhyay, Grace E. Lee, and Duncan W. Wilson

The Amino Terminus of the Herpes Simplex Virus 1 Protein Vhs Mediates Membrane Association and Tegument Incorporation
J. Virol. 2006 80: 10117-10127. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vaccines and Antiviral Agents:

John J. Zaunders, Wayne B. Dyer, Mee Ling Munier, Susanna Ip, Jie Liu, Elisabeth Amyes, William Rawlinson, Robert De Rose, Stephen J. Kent, John S. Sullivan, David A. Cooper, and Anthony D. Kelleher

CD127⁺CCR5⁺CD38⁺⁺⁺ CD4⁺ Th1 Effector Cells Are an Early Component of the Primary Immune Response to Vaccinia Virus and Precede Development of Interleukin-2⁺ Memory CD4⁺ T Cells
J. Virol. 2006 80: 10151-10161. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gene Delivery:

Philip L. Leopold, Rebecca L. Wendland, Theresa Vincent, and Ronald G. Crystal

Neutralized Adenovirus-Immune Complexes Can Mediate Effective Gene Transfer via an Fc Receptor-Dependent Infection Pathway
J. Virol. 2006 80: 10237-10247. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Zsolt Ruzsics, Markus Wagner, Andrea Osterlehner, Jonathan Cook, Ulrich Koszinowski, and Hans-Gerhard Burgert

Transposon-Assisted Cloning and Traceless Mutagenesis of Adenoviruses: Development of a Novel Vector Based on Species D
J. Virol. 2006 80: 10285. [Full Text] [PDF] [Reprints and Permissions]  

Alexander Kotelkin, Igor M. Belyakov, Lijuan Yang, Jay A. Berzofsky, Peter L. Collins, and Alexander Bukreyev

The NS2 Protein of Human Respiratory Syncytial Virus Suppresses the Cytotoxic T-Cell Response as a Consequence of Suppressing the Type I Interferon Response
J. Virol. 2006 80: 10286. [Full Text] [PDF] [Reprints and Permissions]  

Author's Correction:

Volume 80, no. 16, Legend to Cover Photograph
J. Virol. 2006 80: 10287. [Full Text] [PDF] [Reprints and Permissions]  

Yasushi Ami, Yasuyuki Izumi, Kazuhiro Matsuo, Kenji Someya, Masaru Kanekiyo, Shigeo Horibata, Naoto Yoshino, Koji Sakai, Katsuaki Shinohara, Sohkichi Matsumoto, Takeshi Yamada, Shudo Yamazaki, Naoki Yamamoto, and Mitsuo Honda

Priming-Boosting Vaccination with Recombinant Mycobacterium bovis Bacillus Calmette-Guérin and a Nonreplicating Vaccinia Virus Recombinant Leads to Long-Lasting and Effective Immunity
J. Virol. 2006 80: 10288. [Full Text] [PDF] [Reprints and Permissions]  

Retractions:

Eric Ka-Wai Hui, Subrata Barman, Tae Yong Yang, Dominic Ho-Ping Tang, Bryan France, and Debi P. Nayak

"Basic Residues of the Helix Six Domain of Influenza Virus M1 Involved in Nuclear Translocation of M1 Can Be Replaced by PTAP and YPDL Late Assembly Domain Motifs" and "YRKL Sequence of Influenza Virus M1 Functions as the L Domain Motif and Interacts with VPS28 and Cdc42"
J. Virol. 2006 80: 10289. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.