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Contents: January 2006, Volume 80, Issue 2        Spotlight        Genome Replication and Regulation of Viral Gene Expression        Virus-Cell Interactions        Vaccines and Antiviral Agents        Cellular Response to Infection        Structure and Assembly        Pathogenesis and Immunity        Transformation and Oncogenesis        Gene Delivery        Genetic Diversity and Evolution        Author's Correction

Table of Contents

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Spotlight:

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Articles of Significant Interest Selected from This Issue by the Editors J. Virol. January 2006 80: 551-552; [Full Text] [PDF] [Reprints and Permissions]

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Genome Replication and Regulation of Viral Gene Expression:

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Characterization of a Vaccinia Virus Mutant with a Deletion of the D10R Gene Encoding a Putative Negative Regulator of Gene Expression Susan Parrish and Bernard Moss J. Virol. January 2006 80: 553-561; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Point Mutations Upstream of Hepatitis B Virus Core Gene Affect DNA Replication at the Step of Core Protein Expression Michael Guarnieri, Kyun-Hwan Kim, Genie Bang, Jisu Li, Yonghong Zhou, Xiaoli Tang, Jack Wands, and Shuping Tong J. Virol. January 2006 80: 587-595; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of 5' and 3' cis-Acting Elements of the Porcine Reproductive and Respiratory Syndrome Virus: Acquisition of Novel 5' AU-Rich Sequences Restored Replication of a 5'-Proximal 7-Nucleotide Deletion Mutant Yu-Jeong Choi, Sang-Im Yun, Shien-Young Kang, and Young-Min Lee J. Virol. January 2006 80: 723-736; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

UL54-Null Pseudorabies Virus Is Attenuated in Mice but Productively Infects Cells in Culture Jennifer A. Schwartz, Elizabeth E. Brittle, Ashley E. Reynolds, Lynn W. Enquist, and Saul J. Silverstein J. Virol. January 2006 80: 769-784; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Involvement of Template-Activating Factor I/SET in Transcription of Adenovirus Early Genes as a Positive-Acting Factor Hirohito Haruki, Mitsuru Okuwaki, Makoto Miyagishi, Kazunari Taira, and Kyosuke Nagata J. Virol. January 2006 80: 794-801; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Adenovirus E1B 55-Kilodalton Protein Is Required for both Regulation of mRNA Export and Efficient Entry into the Late Phase of Infection in Normal Human Fibroblasts Ramon Gonzalez, Wenying Huang, Renee Finnen, Courtney Bragg, and S. J. Flint J. Virol. January 2006 80: 964-974; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Rescue of Recombinant Marburg Virus from cDNA Is Dependent on Nucleocapsid Protein VP30 Sven Enterlein, Viktor Volchkov, Michael Weik, Larissa Kolesnikova, Valentina Volchkova, Hans-Dieter Klenk, and Elke Mühlberger J. Virol. January 2006 80: 1038-1043; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

ATP Hydrolysis and AMP Kinase Activities of Nonstructural Protein 2C of Human Parechovirus 1 Olga Samuilova, Camilla Krogerus, Igor Fabrichniy, and Timo Hyypiä J. Virol. January 2006 80: 1053-1058; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Nucleocytoplasmic Shuttling of Bovine Herpesvirus 1 UL47 Protein in Infected Cells Janneke Verhagen, Ian Hutchinson, and Gillian Elliott J. Virol. January 2006 80: 1059-1063; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Virus-Cell Interactions:

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Evolution of Broad Host Range in Retroviruses Leads to Cell Death Mediated by Highly Cytopathic Variants G. Jonah A. Rainey and John M. Coffin J. Virol. January 2006 80: 562-570; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The MC160 Protein Expressed by the Dermatotropic Poxvirus Molluscum Contagiosum Virus Prevents Tumor Necrosis Factor Alpha-Induced NF-B Activation via Inhibition of I Kappa Kinase Complex Formation Daniel Brian Nichols and Joanna L. Shisler J. Virol. January 2006 80: 578-586; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inhibition of Protease-Resistant Prion Protein Formation in a Transformed Deer Cell Line Infected with Chronic Wasting Disease Gregory J. Raymond, Emily A. Olsen, Kil Sun Lee, Lynne D. Raymond, P. Kruger Bryant, III, Gerald S. Baron, Winslow S. Caughey, David A. Kocisko, Linda E. McHolland, Cynthia Favara, Jan P. M. Langeveld, Fred G. van Zijderveld, Richard T. Mayer, Michael W. Miller, Elizabeth S. Williams, and Byron Caughey J. Virol. January 2006 80: 596-604; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Addition of N-Glycans in the Stalk of the Newcastle Disease Virus HN Protein Blocks Its Interaction with the F Protein and Prevents Fusion Vanessa R. Melanson and Ronald M. Iorio J. Virol. January 2006 80: 623-633; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Transcription Profile of Aleutian Mink Disease Virus in CRFK Cells Is Generated by Alternative Processing of Pre-mRNAs Produced from a Single Promoter Jianming Qiu, Fang Cheng, Lisa R. Burger, and David Pintel J. Virol. January 2006 80: 654-662; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Expanded Tissue Targets for Foamy Virus Replication with Simian Immunodeficiency Virus-Induced Immunosuppression S. M. Murray, L. J. Picker, M. K. Axthelm, and M. L. Linial J. Virol. January 2006 80: 663-670; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reovirus Variants Selected for Resistance to Ammonium Chloride Have Mutations in Viral Outer-Capsid Protein 3 Kimberly M. Clark, J. Denise Wetzel, Yingqi Gu, Daniel H. Ebert, Stephanie A. McAbee, Emily K. Stoneman, Geoffrey S. Baer, Yuwei Zhu, Gregory J. Wilson, B. V. V. Prasad, and Terence S. Dermody J. Virol. January 2006 80: 671-681; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Live-Cell Characterization and Analysis of a Clinical Isolate of Bovine Respiratory Syncytial Virus, Using Molecular Beacons Philip Santangelo, Nitin Nitin, Leslie LaConte, Amelia Woolums, and Gang Bao J. Virol. January 2006 80: 682-688; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Defining the Cellular Target(s) of Porcine Reproductive and Respiratory Syndrome Virus Blocking Monoclonal Antibody 7G10 Jeong-Ki Kim, Al-Majhdi Fahad, Kumar Shanmukhappa, and Sanjay Kapil J. Virol. January 2006 80: 689-696; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Cytomegalovirus Entry into Epithelial and Endothelial Cells Depends on Genes UL128 to UL150 and Occurs by Endocytosis and Low-pH Fusion Brent J. Ryckman, Michael A Jarvis, Derek D. Drummond, Jay A. Nelson, and David C. Johnson J. Virol. January 2006 80: 710-722; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

7a Protein of Severe Acute Respiratory Syndrome Coronavirus Inhibits Cellular Protein Synthesis and Activates p38 Mitogen-Activated Protein Kinase Sarah A. Kopecky-Bromberg, Luis Martinez-Sobrido, and Peter Palese J. Virol. January 2006 80: 785-793; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Uracil DNA Glycosylase Is Dispensable for Human Immunodeficiency Virus Type 1 Replication and Does Not Contribute to the Antiviral Effects of the Cytidine Deaminase Apobec3G Shari M. Kaiser and Michael Emerman J. Virol. January 2006 80: 875-882; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Cytomegalovirus Immediate-Early 2 Protein IE86 Blocks Virus-Induced Chemokine Expression R. Travis Taylor and Wade A. Bresnahan J. Virol. January 2006 80: 920-928; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Cytomegalovirus Protein pp71 Disrupts Major Histocompatibility Complex Class I Cell Surface Expression Joanne Trgovcich, Colleen Cebulla, Pete Zimmerman, and Daniel D. Sedmak J. Virol. January 2006 80: 951-963; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Low pH-Dependent Endosomal Processing of the Incoming Parvovirus Minute Virus of Mice Virion Leads to Externalization of the VP1 N-Terminal Sequence (N-VP1), N-VP2 Cleavage, and Uncoating of the Full-Length Genome Bernhard Mani, Claudia Baltzer, Noelia Valle, José M. Almendral, Christoph Kempf, and Carlos Ros J. Virol. January 2006 80: 1015-1024; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Vaccines and Antiviral Agents:

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Sequence Homology Required by Human Immunodeficiency Virus Type 1 To Escape from Short Interfering RNAs Rosario Sabariegos, Mireia Giménez-Barcons, Natalia Tàpia, Bonaventura Clotet, and Miguel Angel Martínez J. Virol. January 2006 80: 571-577; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Dynamics of Hepatitis B Virus Resistance to Lamivudine Coralie Pallier, Laurent Castéra, Alexandre Soulier, Christophe Hézode, Patrice Nordmann, Daniel Dhumeaux, and Jean-Michel Pawlotsky J. Virol. January 2006 80: 643-653; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Potent Neutralization of Hendra and Nipah Viruses by Human Monoclonal Antibodies Zhongyu Zhu, Antony S. Dimitrov, Katharine N. Bossart, Gary Crameri, Kimberly A. Bishop, Vidita Choudhry, Bruce A. Mungall, Yan-Ru Feng, Anil Choudhary, Mei-Yun Zhang, Yang Feng, Lin-Fa Wang, Xiaodong Xiao, Bryan T. Eaton, Christopher C. Broder, and Dimiter S. Dimitrov J. Virol. January 2006 80: 891-899; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mefloquine, an Antimalaria Drug with Antiprion Activity In Vitro, Lacks Activity In Vivo David A. Kocisko and Byron Caughey J. Virol. January 2006 80: 1044-1046; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Cellular Response to Infection:

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Restriction of Foamy Viruses by APOBEC Cytidine Deaminases Frédéric Delebecque, Rodolphe Suspène, Sara Calattini, Nicoletta Casartelli, Ali Saïb, Alain Froment, Simon Wain-Hobson, Antoine Gessain, Jean-Pierre Vartanian, and Olivier Schwartz J. Virol. January 2006 80: 605-614; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Host Response to the Attenuated Poxvirus Vector NYVAC: Upregulation of Apoptotic Genes and NF-B-Responsive Genes in Infected HeLa Cells Susana Guerra, Luis A. López-Fernández, Alberto Pascual-Montano, José Luis Nájera, Angel Zaballos, and Mariano Esteban J. Virol. January 2006 80: 985-998; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Varicella-Zoster Virus ORF63 Inhibits Apoptosis of Primary Human Neurons Chantelle Hood, Anthony L. Cunningham, Barry Slobedman, Ann M. Arvin, Marvin H. Sommer, Paul R. Kinchington, and Allison Abendroth J. Virol. January 2006 80: 1025-1031; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interferon Regulatory Factor 3 Is Necessary for Induction of Antiviral Genes during Human Cytomegalovirus Infection Victor R. DeFilippis, Bridget Robinson, Thomas M. Keck, Scott G. Hansen, Jay A. Nelson, and Klaus J. Früh J. Virol. January 2006 80: 1032-1037; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

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Structure and Assembly:

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Morphological Changes in the T=3 Capsid of Flock House Virus during Cell Entry Hanna E. Walukiewicz, John E. Johnson, and Anette Schneemann J. Virol. January 2006 80: 615-622; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Membrane-Destabilizing Peptide in Capsid Protein L2 Is Required for Egress of Papillomavirus Genomes from Endosomes Nadine Kämper, Patricia M. Day, Thorsten Nowak, Hans-Christoph Selinka, Luise Florin, Jan Bolscher, Lydia Hilbig, John T. Schiller, and Martin Sapp J. Virol. January 2006 80: 759-768; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Impact of Capsid Conformation and Rep-Capsid Interactions on Adeno-Associated Virus Type 2 Genome Packaging Svenja Bleker, Michael Pawlita, and Jürgen A. Kleinschmidt J. Virol. January 2006 80: 810-820; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Functional Analysis of the Triplex Proteins (VP19C and VP23) of Herpes Simplex Virus Type 1 Mercy E. Okoye, Gerry L. Sexton, Eugene Huang, J. Michael McCaffery, and Prashant Desai J. Virol. January 2006 80: 929-940; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pathogenesis and Immunity:

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Perturbations of Cell Cycle Control in T Cells Contribute to the Different Outcomes of Simian Immunodeficiency Virus Infection in Rhesus Macaques and Sooty Mangabeys M. Paiardini, B. Cervasi, B. Sumpter, H. M. McClure, D. L. Sodora, M. Magnani, S. I. Staprans, G. Piedimonte, and G. Silvestri J. Virol. January 2006 80: 634-642; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of Ross River Virus Tropism and Virus-Induced Inflammation in a Mouse Model of Viral Arthritis and Myositis Thomas E. Morrison, Alan C. Whitmore, Reed S. Shabman, Brett A. Lidbury, Suresh Mahalingam, and Mark T. Heise J. Virol. January 2006 80: 737-749; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Immunodeficiency Virus Type 1 Coreceptor Switching: V1/V2 Gain-of-Fitness Mutations Compensate for V3 Loss-of-Fitness Mutations C. Pastore, R. Nedellec, A. Ramos, S. Pontow, L. Ratner, and D. E. Mosier J. Virol. January 2006 80: 750-758; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Naïve and Memory Cell Turnover as Drivers of CCR5-to-CXCR4 Tropism Switch in Human Immunodeficiency Virus Type 1: Implications for Therapy Ruy M. Ribeiro, Mette D. Hazenberg, Alan S. Perelson, and Miles P. Davenport J. Virol. January 2006 80: 802-809; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Neutralization Escape Variants of Human Immunodeficiency Virus Type 1 Are Transmitted from Mother to Infant Xueling Wu, Adam B. Parast, Barbra A. Richardson, Ruth Nduati, Grace John-Stewart, Dorothy Mbori-Ngacha, Stephanie M. J. Rainwater, and Julie Overbaugh J. Virol. January 2006 80: 835-844; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Epstein-Barr Virus (EBV) Genome and Expression in Breast Cancer Tissue: Effect of EBV Infection of Breast Cancer Cells on Resistance to Paclitaxel (Taxol) Hratch Arbach, Viktor Viglasky, Florence Lefeu, Jean-Marc Guinebretière, Vanessa Ramirez, Nadège Bride, Nadia Boualaga, Thomas Bauchet, Jean-Philippe Peyrat, Marie-Christine Mathieu, Samia Mourah, Marie-Pierre Podgorniak, Jean-Marie Seignerin, Kenzo Takada, and Irène Joab J. Virol. January 2006 80: 845-853; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

R5 Variants of Human Immunodeficiency Virus Type 1 Preferentially Infect CD62L– CD4+ T Cells and Are Potentially Resistant to Nucleoside Reverse Transcriptase Inhibitors Françoise Gondois-Rey, Angelique Biancotto, Marcelo Antonio Fernandez, Lise Bettendroffer, Jana Blazkova, Katerina Trejbalova, Marjorie Pion, and Ivan Hirsch J. Virol. January 2006 80: 854-865; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Hepatitis C Virus Induces Toll-Like Receptor 4 Expression, Leading to Enhanced Production of Beta Interferon and Interleukin-6 Keigo Machida, Kevin T. H. Cheng, Vicky M.-H. Sung, Alexandra M. Levine, Steven Foung, and Michael M. C. Lai J. Virol. January 2006 80: 866-874; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Three Immunoproteasome-Associated Subunits Cooperatively Generate a Cytotoxic T-Lymphocyte Epitope of Epstein-Barr Virus LMP2A by Overcoming Specific Structures Resistant to Epitope Liberation Yoshinori Ito, Eisei Kondo, Ayako Demachi-Okamura, Yoshiki Akatsuka, Kunio Tsujimura, Mitsune Tanimoto, Yasuo Morishima, Toshitada Takahashi, and Kiyotaka Kuzushima J. Virol. January 2006 80: 883-890; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Amino-Terminal Domain of Bovine Viral Diarrhea Virus Npro Protein Is Necessary for Alpha/Beta Interferon Antagonism Laura H. V. G. Gil, Israrul H. Ansari, Ventzislav Vassilev, Delin Liang, Vicky C. H. Lai, Weidong Zhong, Zhi Hong, Edward J. Dubovi, and Ruben O. Donis J. Virol. January 2006 80: 900-911; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Immune Response to Individual Maedi-Visna Virus gag Antigens Inderpal Singh, Ian McConnell, and Barbara Blacklaws J. Virol. January 2006 80: 912-919; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Monoclonal Antibodies Targeting the HR2 Domain and the Region Immediately Upstream of the HR2 of the S Protein Neutralize In Vitro Infection of Severe Acute Respiratory Syndrome Coronavirus Kuo-Ming Lip, Shuo Shen, Xiaoming Yang, Choong-Tat Keng, Aihua Zhang, Hsueh-Ling Janice Oh, Zhi-Hong Li, Le-Ann Hwang, Chih-Fong Chou, Burtram C. Fielding, Timothy H. P. Tan, Josef Mayrhofer, Falko G. Falkner, Jianlin Fu, Seng Gee Lim, Wanjin Hong, and Yee-Joo Tan J. Virol. January 2006 80: 941-950; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Consistent Patterns of Change during the Divergence of Human Immunodeficiency Virus Type 1 Envelope from That of the Inoculated Virus in Simian/Human Immunodeficiency Virus-Infected Macaques W.M. Blay, S. Gnanakaran, B. Foley, N. A. Doria-Rose, B. T. Korber, and N. L. Haigwood J. Virol. January 2006 80: 999-1014; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Transformation and Oncogenesis:

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Kaposi's Sarcoma-Associated Herpesvirus-Encoded Latency-Associated Nuclear Antigen Induces Chromosomal Instability through Inhibition of p53 Function Huaxin Si and Erle S. Robertson J. Virol. January 2006 80: 697-709; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Gene Delivery:

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Mutations on the External Surfaces of Adeno-Associated Virus Type 2 Capsids That Affect Transduction and Neutralization Michael A. Lochrie, Gwen P. Tatsuno, Brian Christie, Jennifer Wellman McDonnell, Shangzhen Zhou, Richard Surosky, Glenn F. Pierce, and Peter Colosi J. Virol. January 2006 80: 821-834; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Genetic Diversity and Evolution:

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Natural History of Human Respiratory Syncytial Virus Inferred from Phylogenetic Analysis of the Attachment (G) Glycoprotein with a 60-Nucleotide Duplication Alfonsina Trento, Mariana Viegas, Mónica Galiano, Cristina Videla, Guadalupe Carballal, Alicia S. Mistchenko, and José A. Melero J. Virol. January 2006 80: 975-984; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Longitudinal Analysis of Human Immunodeficiency Virus Type 1 nef/Long Terminal Repeat Sequences in a Cohort of Long-Term Survivors Infected from a Single Source Melissa J. Churchill, David I. Rhodes, Jennifer C. Learmont, John S. Sullivan, Steven L. Wesselingh, Ian R. C. Cooke, Nicholas J. Deacon, and Paul R. Gorry J. Virol. January 2006 80: 1047-1052; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Author's Correction:

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Short Interfering RNA Accumulation Correlates with Host Recovery in DNA Virus-Infected Hosts, and Gene Silencing Targets Specific Viral Sequences Padmanabhan Chellappan, Ramachandran Vanitharani, Justin Pita, and Claude M. Fauquet J. Virol. January 2006 80: 1064 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.