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Contents: December 2005, Volume 79, Issue 23        Spotlight        Transformation and Oncogenesis        Virus-Cell Interactions        Structure and Assembly        Gene Delivery        Pathogenesis and Immunity        Genome Replication and Regulation of Viral Gene Expression        Cellular Response to Infection        Vaccines and Antiviral Agents        Genetic Diversity and Evolution        Errata

Table of Contents

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Spotlight:

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Articles of Significant Interest Selected from This Issue by the Editors J. Virol. December 2005 79: 14471-14472; [Full Text] [PDF] [Reprints and Permissions]

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Transformation and Oncogenesis:

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Human T-Cell Leukemia Virus Type 1 Expressing Nonoverlapping Tax and Rex Genes Replicates and Immortalizes Primary Human T Lymphocytes but Fails To Replicate and Persist In Vivo Ihab Younis, Brenda Yamamoto, Andrew Phipps, and Patrick L. Green J. Virol. December 2005 79: 14473-14481; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Murine Gammaherpesvirus 68 Infection Is Associated with Lymphoproliferative Disease and Lymphoma in BALB ß2 Microglobulin-Deficient Mice Vera L. Tarakanova, Felipe Suarez, Scott A. Tibbetts, Meagan A. Jacoby, Karen E. Weck, Jay L. Hess, Samuel H. Speck, and Herbert W. Virgin, IV J. Virol. December 2005 79: 14668-14679; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Skin Hyperproliferation and Susceptibility to Chemical Carcinogenesis in Transgenic Mice Expressing E6 and E7 of Human Papillomavirus Type 38 Wen Dong, Ulrich Kloz, Rosita Accardi, Sandra Caldeira, Wei-Min Tong, Zhao-Qi Wang, Lars Jansen, Matthias Dürst, Bakary S. Sylla, Lutz Gissmann, and Massimo Tommasino J. Virol. December 2005 79: 14899-14908; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Virus-Cell Interactions:

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Endocytosis and a Low-pH Step Are Required for Productive Entry of Equine Infectious Anemia Virus Melinda A. Brindley and Wendy Maury J. Virol. December 2005 79: 14482-14488; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Receptor-Mediated Entry by Equine Infectious Anemia Virus Utilizes a pH-Dependent Endocytic Pathway Sha Jin, Baoshan Zhang, Ora A. Weisz, and Ronald C. Montelaro J. Virol. December 2005 79: 14489-14497; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

ACE2 Receptor Expression and Severe Acute Respiratory Syndrome Coronavirus Infection Depend on Differentiation of Human Airway Epithelia Hong Peng Jia, Dwight C. Look, Lei Shi, Melissa Hickey, Lecia Pewe, Jason Netland, Michael Farzan, Christine Wohlford-Lenane, Stanley Perlman, and Paul B. McCray, Jr J. Virol. December 2005 79: 14614-14621; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Functional Divergence of Kaposi's Sarcoma-Associated Herpesvirus and Related Gamma-2 Herpesvirus Thymidine Kinases: Novel Cytoplasmic Phosphoproteins That Alter Cellular Morphology and Disrupt Adhesion Michael B. Gill, Jo-Ellen Murphy, and Joyce D. Fingeroth J. Virol. December 2005 79: 14647-14659; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Mutation in the First Ligand-Binding Repeat of the Human Very-Low-Density Lipoprotein Receptor Results in High-Affinity Binding of the Single V1 Module to Human Rhinovirus 2 Stephane Nizet, Juergen Wruss, Nathalie Landstetter, Luc Snyers, and Dieter Blaas J. Virol. December 2005 79: 14730-14736; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Contribution of GADD45 Family Members to Cell Death Suppression by Cellular Bcl-xL and Cytomegalovirus vMIA Geoffrey B. Smith and Edward S. Mocarski J. Virol. December 2005 79: 14923-14932; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Hydrophobic Domain in the Large Envelope Protein Is Essential for Fusion of Duck Hepatitis B Virus at the Late Endosome J. Chojnacki, D. A. Anderson, and E. V. L. Grgacic J. Virol. December 2005 79: 14945-14955; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inhibition of E2 Binding to Brd4 Enhances Viral Genome Loss and Phenotypic Reversion of Bovine Papillomavirus-Transformed Cells Jianxin You, Michal-Ruth Schweiger, and Peter M. Howley J. Virol. December 2005 79: 14956-14961; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of Two Residues within the LDL-A Module of Tva That Dictate the Altered Receptor Specificity of Mutant Subgroup A Avian Sarcoma and Leukosis Viruses Tia Rai, Michael Caffrey, and Lijun Rong J. Virol. December 2005 79: 14962-14966; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Sensitization to Apoptosis Underlies KrasD12-Dependent Oncolysis of Murine C26 Colorectal Carcinoma Cells by Reovirus T3D Niels Smakman, Diana J. M. van den Wollenberg, Inne H. M. Borel Rinkes, Rob C. Hoeben, and Onno Kranenburg J. Virol. December 2005 79: 14981-14985; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Structure and Assembly:

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Analysis of Human Immunodeficiency Virus Type 1 Gag Dimerization-Induced Assembly Ayna Alfadhli, Tenzin Choesang Dhenub, Amelia Still, and Eric Barklis J. Virol. December 2005 79: 14498-14506; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Homo-Oligomerization of Marburgvirus VP35 Is Essential for Its Function in Replication and Transcription Peggy Möller, Nonia Pariente, Hans-Dieter Klenk, and Stephan Becker J. Virol. December 2005 79: 14876-14886; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Gene Delivery:

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Akt/Protein Kinase B Activation by Adenovirus Vectors Contributes to NFB-Dependent CXCL10 Expression Qiang Liu, Lindsay R. White, Sharon A. Clark, Daniel J. Heffner, Brent W. Winston, Lee Anne Tibbles, and Daniel A. Muruve J. Virol. December 2005 79: 14507-14515; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Neutrophils Interact with Adenovirus Vectors via Fc Receptors and Complement Receptor 1 Matthew J. Cotter, Anne K. Zaiss, and Daniel A. Muruve J. Virol. December 2005 79: 14622-14631; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pathogenesis and Immunity:

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Herpes Simplex Virus 1 Immediate-Early and Early Gene Expression during Reactivation from Latency under Conditions That Prevent Infectious Virus Production Jean M. Pesola, Jia Zhu, David M. Knipe, and Donald M. Coen J. Virol. December 2005 79: 14516-14525; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interaction of Rotavirus with Human Myeloid Dendritic Cells Carlos F. Narváez, Juana Angel, and Manuel A. Franco J. Virol. December 2005 79: 14526-14535; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Envelope Is a Major Viral Determinant of the Distinct In Vitro Cellular Transformation Tropism of Human T-Cell Leukemia Virus Type 1 (HTLV-1) and HTLV-2 Li Xie and Patrick L. Green J. Virol. December 2005 79: 14536-14545; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Clearance of Herpes Simplex Virus Type 2 by CD8+ T Cells Requires Gamma Interferon and either Perforin- or Fas-Mediated Cytolytic Mechanisms Melanie E. Dobbs, Jane E. Strasser, Chin-Fun Chu, Claudia Chalk, and Gregg N. Milligan J. Virol. December 2005 79: 14546-14554; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Resistance to Friend Virus-Induced Erythroleukemia in W/Wv Mice Is Caused by a Spleen-Specific Defect Which Results in a Severe Reduction in Target Cells and a Lack of Sf-Stk Expression Aparna Subramanian, Hami E. Teal, Pamela H. Correll, and Robert F. Paulson J. Virol. December 2005 79: 14586-14594; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Cotton Rat Provides a Novel Model To Study Genital Herpes Infection and To Evaluate Preventive Strategies Kevin C. Yim, Clifford J. Carroll, Ana Tuyama, Natalia Cheshenko, Maria Josefina Carlucci, David D. Porter, Gregory A. Prince, and Betsy C. Herold J. Virol. December 2005 79: 14632-14639; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Central Nervous System Pathology Caused by Autoreactive CD8+ T-Cell Clones following Virus Infection Ikuo Tsunoda, Li-Qing Kuang, Mikako Kobayashi-Warren, and Robert S. Fujinami J. Virol. December 2005 79: 14640-14646; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antigen Expression Kinetics and Immune Responses of Mice Immunized with Noninfectious Simian-Human Immunodeficiency Virus DNA Ramakrishna Hegde, ZhenQian Liu, Glenn Mackay, Marilyn Smith, Yahia Chebloune, Opendra Narayan, and Dinesh K. Singh J. Virol. December 2005 79: 14688-14697; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Neuronal Host Cell Factor-Binding Protein Zhangfei Inhibits Herpes Simplex Virus Replication Oksana Akhova, Matthew Bainbridge, and Vikram Misra J. Virol. December 2005 79: 14708-14718; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Single-Molecule Analysis of Human Immunodeficiency Virus Type 1 gp120-Receptor Interactions in Living Cells Melissa I. Chang, Porntula Panorchan, Terrence M. Dobrowsky, Yiider Tseng, and Denis Wirtz J. Virol. December 2005 79: 14748-14755; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Parainfluenza Virus Type 4 Is Incapable of Evading the Interferon-Induced Antiviral Effect Machiko Nishio, Masato Tsurudome, Morihiro Ito, and Yasuhiko Ito J. Virol. December 2005 79: 14756-14768; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Wild Goose Metapneumovirus Containing a Large Attachment Glycoprotein Is Avirulent but Immunoprotective in Domestic Turkeys Richard S. Bennett, Rebecca LaRue, Daniel Shaw, Qingzhong Yu, K. V. Nagaraja, David A. Halvorson, and M. Kariuki Njenga J. Virol. December 2005 79: 14834-14842; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Latent Infection with Herpes Simplex Virus Is Associated with Ongoing CD8+ T-Cell Stimulation by Parenchymal Cells within Sensory Ganglia Allison L. van Lint, Lauren Kleinert, Sally R. M. Clarke, Angus Stock, William R. Heath, and Francis R. Carbone J. Virol. December 2005 79: 14843-14851; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Decreased Migration of Langerhans Precursor-Like Cells in Response to Human Keratinocytes Expressing Human Papillomavirus Type 16 E6/E7 Is Related to Reduced Macrophage Inflammatory Protein-3 Production Jennifer C. Guess and Dennis J. McCance J. Virol. December 2005 79: 14852-14862; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

CD8+ and CD20+ Lymphocytes Cooperate To Control Acute Simian Immunodeficiency Virus/Human Immunodeficiency Virus Chimeric Virus Infections in Rhesus Monkeys: Modulation by Major Histocompatibility Complex Genotype Hanwen Mao, Bernard A. P. Lafont, Tatsuhiko Igarashi, Yoshiaki Nishimura, Charlie Brown, Vanessa Hirsch, Alicia Buckler-White, Reza Sadjadpour, and Malcolm A. Martin J. Virol. December 2005 79: 14887-14898; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pathogenicity of Influenza Viruses with Genes from the 1918 Pandemic Virus: Functional Roles of Alveolar Macrophages and Neutrophils in Limiting Virus Replication and Mortality in Mice Terrence M. Tumpey, Adolfo García-Sastre, Jeffery K. Taubenberger, Peter Palese, David E. Swayne, Mary J. Pantin-Jackwood, Stacey Schultz-Cherry, Alicia Solórzano, Nico Van Rooijen, Jacqueline M. Katz, and Christopher F. Basler J. Virol. December 2005 79: 14933-14944; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Breaking an Absolute Species Barrier: Transgenic Mice Expressing the Mink PrP Gene Are Susceptible to Transmissible Mink Encephalopathy O. Windl, M. Buchholz, A. Neubauer, W. Schulz-Schaeffer, M. Groschup, S. Walter, S. Arendt, M. Neumann, A. K. Voss, and H. A. Kretzschmar J. Virol. December 2005 79: 14971-14975; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Tat28-35SL8-Specific CD8+ T Lymphocytes Are More Effective than Gag181-189CM9-Specific CD8+ T Lymphocytes at Suppressing Simian Immunodeficiency Virus Replication in a Functional In Vitro Assay John T. Loffredo, Eva G. Rakasz, Juan Pablo Giraldo, Sean P. Spencer, Kelly K. Grafton, Sarah R. Martin, Gnankang Napoé, Levi J. Yant, Nancy A. Wilson, and David I. Watkins J. Virol. December 2005 79: 14986-14991; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Metapneumovirus Induces a Profile of Lung Cytokines Distinct from That of Respiratory Syncytial Virus Antonieta Guerrero-Plata, Antonella Casola, and Roberto P. Garofalo J. Virol. December 2005 79: 14992-14997; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Genome Replication and Regulation of Viral Gene Expression:

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The AAUAAA Motif of Bamboo Mosaic Virus RNA Is Involved in Minus-Strand RNA Synthesis and Plus-Strand RNA Polyadenylation I-Hsuan Chen, Wen-Jen Chou, Pei-Yu Lee, Yau-Heiu Hsu, and Ching-Hsiu Tsai J. Virol. December 2005 79: 14555-14561; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Mutations in the Mouse Hepatitis Virus 3'(+)42 Protein Binding Element on RNA Replication Reed F. Johnson, Min Feng, Pinghua Liu, Jason J. Millership, Boyd Yount, Ralph S. Baric, and Julian L. Leibowitz J. Virol. December 2005 79: 14570-14585; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Conserved Poxvirus L3 Virion Protein Is Required for Transcription of Vaccinia Virus Early Genes Wolfgang Resch and Bernard Moss J. Virol. December 2005 79: 14719-14729; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mouse Mammary Tumor Virus Encodes a Self-Regulatory RNA Export Protein and Is a Complex Retrovirus Jennifer A. Mertz, Melissa S. Simper, Mary M. Lozano, Shelley M. Payne, and Jaquelin P. Dudley J. Virol. December 2005 79: 14737-14747; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interactions with Pocket Proteins Contribute to the Role of Human Papillomavirus Type 16 E7 in the Papillomavirus Life Cycle Asha S. Collins, Tomomi Nakahara, Anh Do, and Paul F. Lambert J. Virol. December 2005 79: 14769-14780; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Characterization of Adeno-Associated Viruses Infecting Children Chun-Liang Chen, Ryan L. Jensen, Bruce C. Schnepp, Mary J. Connell, Richard Shell, Thomas J. Sferra, Jeffrey S. Bartlett, K. Reed Clark, and Philip R. Johnson J. Virol. December 2005 79: 14781-14792; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of Adeno-Associated Virus Genomes Isolated from Human Tissues Bruce C. Schnepp, Ryan L. Jensen, Chun-Liang Chen, Philip R. Johnson, and K. Reed Clark J. Virol. December 2005 79: 14793-14803; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Specific Recognition and Cleavage of the Plus-Strand Primer by Reverse Transcriptase Angela Atwood-Moore, Kenechi Ejebe, and Henry L. Levin J. Virol. December 2005 79: 14863-14875; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Severe Acute Respiratory Syndrome Coronavirus Group-Specific Open Reading Frames Encode Nonessential Functions for Replication in Cell Cultures and Mice Boyd Yount, Rhonda S. Roberts, Amy C. Sims, Damon Deming, Matthew B. Frieman, Jennifer Sparks, Mark R. Denison, Nancy Davis, and Ralph S. Baric J. Virol. December 2005 79: 14909-14922; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Cellular Response to Infection:

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Protection from Interferon-Induced Apoptosis by Epstein-Barr Virus Small RNAs Is Not Mediated by Inhibition of PKR Ingrid K. Ruf, Kristen A. Lackey, Swati Warudkar, and Jeffery T. Sample J. Virol. December 2005 79: 14562-14569; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Frequency, Proliferation, and Activation of Human Memory T Cells Induced by a Nonhuman Adenovirus Matthieu Perreau and Eric J. Kremer J. Virol. December 2005 79: 14595-14605; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activation of p21-Activated Kinase 2 by Human Immunodeficiency Virus Type 1 Nef Induces Merlin Phosphorylation Bangdong L. Wei, Vivek K. Arora, Alexa Raney, Lillian S. Kuo, Guang-Hui Xiao, Eduardo O'Neill, Joseph R. Testa, John L. Foster, and J. Victor Garcia J. Virol. December 2005 79: 14976-14980; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Vaccines and Antiviral Agents:

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Protective and Therapeutic Capacity of Human Single-Chain Fv-Fc Fusion Proteins against West Nile Virus L. Hannah Gould, Jianhua Sui, Harald Foellmer, Theodore Oliphant, Tian Wang, Michel Ledizet, Akikazu Murakami, Kristin Noonan, Cassandra Lambeth, Kalipada Kar, John F. Anderson, Aravinda M. de Silva, Michael S. Diamond, Raymond A. Koski, Wayne A. Marasco, and Erol Fikrig J. Virol. December 2005 79: 14606-14613; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interaction of the Putative Human Cytomegalovirus Portal Protein pUL104 with the Large Terminase Subunit pUL56 and Its Inhibition by Benzimidazole-D-Ribonucleosides Alexandra Dittmer, John C. Drach, Leroy B. Townsend, Anke Fischer, and Elke Bogner J. Virol. December 2005 79: 14660-14667; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Induction of Neutralizing Antibodies against Human Immunodeficiency Virus Type 1 Primary Isolates by Gag-Env Pseudovirion Immunization Jason Hammonds, Xuemin Chen, Timothy Fouts, Anthony DeVico, David Montefiori, and Paul Spearman J. Virol. December 2005 79: 14804-14814; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Cell Cycle Arrest on the Activity of Nucleoside Analogues against Human Immunodeficiency Virus Type 1 Sebastien Wurtzer, Séverine Compain, Henri Benech, Allan J. Hance, and François Clavel J. Virol. December 2005 79: 14815-14821; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Induction of Human Immunodeficiency Virus Type 1-Specific T Cells by a Bluetongue Virus Tubule-Vectored Vaccine Prime-Recombinant Modified Virus Ankara Boost Regimen Natasha Larke, Aileen Murphy, Christoph Wirblich, Denise Teoh, Marie J. Estcourt, Andrew J. McMichael, Polly Roy, and Tomás Hanke J. Virol. December 2005 79: 14822-14833; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Genetic Diversity and Evolution:

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Invasion and Maintenance of Dengue Virus Type 2 and Type 4 in the Americas Christine V. F. Carrington, Jerome E. Foster, Oliver G. Pybus, Shannon N. Bennett, and Edward C. Holmes J. Virol. December 2005 79: 14680-14687; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

MysTR: an Endogenous Retrovirus Family in Mammals That Is Undergoing Recent Amplifications to Unprecedented Copy Numbers Michael A. Cantrell, Martina M. Ederer, Issac K. Erickson, Vicki J. Swier, Robert J. Baker, and Holly A. Wichman J. Virol. December 2005 79: 14698-14707; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Common Ancestry of Herpesviruses and Tailed DNA Bacteriophages Matthew L. Baker, Wen Jiang, Frazer J. Rixon, and Wah Chiu J. Virol. December 2005 79: 14967-14970; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Evolution of Cyclophilin A and TRIMCyp Retrotransposition in New World Primates Ieda P. Ribeiro, Albert N. Menezes, Miguel A. M. Moreira, Cibele R. Bonvicino, Héctor N. Seuánez, and Marcelo A. Soares J. Virol. December 2005 79: 14998-15003; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Errata:

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Protein Kinase C Is Not Essential for T-Cell-Mediated Clearance of Murine Gammaherpesvirus 68 Francesca Giannoni, Ashley B. Lyon, Mark D. Wareing, Peter B. Dias, and Sally R. Sarawar J. Virol. December 2005 79: 15004 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.