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Contents: April 2003, Volume 77, Issue 8        Replication        Virus-Cell Interactions        Pathogenesis and Immunity        Recombination and Evolution        Structure and Assembly        Transformation and Oncogenesis        Vaccines and Antiviral Agents        Gene Therapy

Table of Contents

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Replication:

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Heat Shock Protein 90-Independent Activation of Truncated Hepadnavirus Reverse Transcriptase Xingtai Wang, Xiaofeng Qian, Hwai-Chen Guo, and Jianming Hu J. Virol. April 2003 77: 4471-4480; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Subcellular Localization of Feline Immunodeficiency Virus Integrase and Mapping of Its Karyophilic Determinant Cora L. Woodward, Yao Wang, Wendy J. Dixon, Han Htun, and Samson A. Chow J. Virol. April 2003 77: 4516-4527; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Poliovirus CRE-Dependent VPg Uridylylation Is Required for Positive-Strand RNA Synthesis but Not for Negative-Strand RNA Synthesis Kenneth E. Murray and David J. Barton J. Virol. April 2003 77: 4739-4750; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Immunodeficiency Virus Type 1 Assembly and Lipid Rafts: Pr55gag Associates with Membrane Domains That Are Largely Resistant to Brij98 but Sensitive to Triton X-100 Kirsi Holm, Katarzyna Weclewicz, Roger Hewson, and Maarit Suomalainen J. Virol. April 2003 77: 4805-4817; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Synthetic E7 Gene of Human Papillomavirus Type 16 That Yields Enhanced Expression of the Protein in Mammalian Cells and Is Useful for DNA Immunization Studies Angel Cid-Arregui, Victoria Juárez, and Harald zur Hausen J. Virol. April 2003 77: 4928-4937; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Single Amino Acid Mutation in the PA Subunit of the Influenza Virus RNA Polymerase Promotes the Generation of Defective Interfering RNAs Ervin Fodor, Louise J. Mingay, Mandy Crow, Tao Deng, and George G. Brownlee J. Virol. April 2003 77: 5017-5020; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Virus-Cell Interactions:

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Silencing of the Baculovirus Op-iap3 Gene by RNA Interference Reveals that It Is Required for Prevention of Apoptosis during Orgyia pseudotsugata M Nucleopolyhedrovirus Infection of Ld652Y Cells John C. Means, Israel Muro, and Rollie J. Clem J. Virol. April 2003 77: 4481-4488; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Constitutive Inositol Phosphate Formation in Cytomegalovirus-Infected Human Fibroblasts Is due to Expression of the Chemokine Receptor Homologue pUS28 Rosalba Minisini, Calogero Tulone, Anke Lüske, Detlef Michel, Thomas Mertens, Peter Gierschik, and Barbara Moepps J. Virol. April 2003 77: 4489-4501; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reovirus NS Protein Localizes to Inclusions through an Association Requiring the µNS Amino Terminus Cathy L. Miller, Teresa J. Broering, John S. L. Parker, Michelle M. Arnold, and Max L. Nibert J. Virol. April 2003 77: 4566-4576; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Cytomegalovirus Activates Inflammatory Cytokine Responses via CD14 and Toll-Like Receptor 2 Teresa Compton, Evelyn A. Kurt-Jones, Karl W. Boehme, John Belko, Eicke Latz, Douglas T. Golenbock, and Robert W. Finberg J. Virol. April 2003 77: 4588-4596; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Respiratory Syncytial Virus (RSV) Fusion Protein Subunit F2, Not Attachment Protein G, Determines the Specificity of RSV Infection Jörg Schlender, Gert Zimmer, Georg Herrler, and Karl-Klaus Conzelmann J. Virol. April 2003 77: 4609-4616; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Ability of the Matrix Protein of Vesicular Stomatitis Virus To Suppress Beta Interferon Gene Expression Is Genetically Correlated with the Inhibition of Host RNA and Protein Synthesis Maryam Ahmed, Margie O. McKenzie, Shelby Puckett, Michael Hojnacki, Laurent Poliquin, and Douglas S. Lyles J. Virol. April 2003 77: 4646-4657; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Contrasting Effects of Matrix Protein on Apoptosis in HeLa and BHK Cells Infected with Vesicular Stomatitis Virus Are due to Inhibition of Host Gene Expression Sarah A. Kopecky and Douglas S. Lyles J. Virol. April 2003 77: 4658-4669; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Foamy Virus Envelope Glycoprotein-Mediated Entry Involves a pH-Dependent Fusion Process Marcus Picard-Maureau, Gergely Jarmy, Angelika Berg, Axel Rethwilm, and Dirk Lindemann J. Virol. April 2003 77: 4722-4730; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Cytomegalovirus US3 Chimeras Containing US2 Cytosolic Residues Acquire Major Histocompatibility Class I and II Protein Degradation Properties Mathieu S. Chevalier and David C. Johnson J. Virol. April 2003 77: 4731-4738; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Strain Variations in Single Amino Acids of the 86-Kilodalton Human Cytomegalovirus Major Immediate-Early Protein (IE2) Affect Its Functional and Biochemical Properties: Implications of Dynamic Protein Conformation M. Inmaculada Barrasa, Noam Harel, Yongjun Yu, and James C. Alwine J. Virol. April 2003 77: 4760-4772; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Changes in Rhinovirus Protein 2C Allow Efficient Replication in Mouse Cells Julie R. Harris and Vincent R. Racaniello J. Virol. April 2003 77: 4773-4780; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of ESCRT-I in Retroviral Budding Juan Martin-Serrano, Trinity Zang, and Paul D. Bieniasz J. Virol. April 2003 77: 4794-4804; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Binding of Adenovirus Capsid to Dipalmitoyl Phosphatidylcholine Provides a Novel Pathway for Virus Entry Larissa Balakireva, Guy Schoehn, Eric Thouvenin, and Jadwiga Chroboczek J. Virol. April 2003 77: 4858-4866; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Packaging of Human Chromosome 19-Specific Adeno-Associated Virus (AAV) Integration Sites in AAV Virions during AAV Wild-Type and Recombinant AAV Vector Production Daniela Hüser, Stefan Weger, and Regine Heilbronn J. Virol. April 2003 77: 4881-4887; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Regulation of Host Cell Transcriptional Physiology by the Avian Pneumovirus Provides Key Insights into Host-Pathogen Interactions Shirin Munir and Vivek Kapur J. Virol. April 2003 77: 4899-4910; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Adenovirus Dodecahedron Allows Large Multimeric Protein Transduction in Human Cells P. Fender, G. Schoehn, J. Foucaud-Gamen, E. Gout, A. Garcel, E. Drouet, and J. Chroboczek J. Virol. April 2003 77: 4960-4964; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Localization of CD4 and CCR5 in Living Cells Carolyn M. Steffens and Thomas J. Hope J. Virol. April 2003 77: 4985-4991; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Herpesvirus 6 Variant A Glycoprotein H-Glycoprotein L-Glycoprotein Q Complex Associates with Human CD46 Yasuko Mori, Xuwei Yang, Pilailuk Akkapaiboon, Toshiomi Okuno, and Koichi Yamanishi J. Virol. April 2003 77: 4992-4999; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Latent Membrane Protein 1 Inhibits Epstein-Barr Virus Lytic Cycle Induction and Progress via Different Mechanisms Stuart Prince, Sinead Keating, Ceri Fielding, Paul Brennan, Eike Floettmann, and Martin Rowe J. Virol. April 2003 77: 5000-5007; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Epstein-Barr Virus Nuclear Antigen 2 Binds via Its Methylated Arginine-Glycine Repeat to the Survival Motor Neuron Protein Stephanie Barth, Michael Liss, Marc D. Voss, Thomas Dobner, Utz Fischer, Gunter Meister, and Friedrich A. Grässer J. Virol. April 2003 77: 5008-5013; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Processing of eIF4GI by Human Rhinovirus Type 2 2Apro: Relationship to Self-Cleavage and Role of Zinc Walter Glaser, Andrea Triendl, and Tim Skern J. Virol. April 2003 77: 5021-5025; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Rhinovirus 2A Proteinase Cleavage Sites in Eukaryotic Initiation Factors (eIF) 4GI and eIF4GII Are Different Alessandra Gradi, Yuri V. Svitkin, Wolfgang Sommergruber, Hiroaki Imataka, Shigenobu Morino, Tim Skern, and Nahum Sonenberg J. Virol. April 2003 77: 5026-5029; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Barrier-to-Autointegration Factor Is a Component of Functional Human Immunodeficiency Virus Type 1 Preintegration Complexes Chou-Wen Lin and Alan Engelman J. Virol. April 2003 77: 5030-5036; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pathogenesis and Immunity:

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CXCL10 Production from Cytomegalovirus-Stimulated Microglia Is Regulated by both Human and Viral Interleukin-10 Maxim C.-J. Cheeran, Shuxian Hu, Wen S. Sheng, Phillip K. Peterson, and James R. Lokensgard J. Virol. April 2003 77: 4502-4515; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Human Cytomegalovirus Protein UL16 Mediates Increased Resistance to Natural Killer Cell Cytotoxicity through Resistance to Cytolytic Proteins Jenny Odeberg, Helena Browne, Sunil Metkar, Christopher J. Froelich, Lars Brandén, David Cosman, and Cecilia Söderberg-Nauclér J. Virol. April 2003 77: 4539-4545; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Progesterone Increases Susceptibility and Decreases Immune Responses to Genital Herpes Infection Charu Kaushic, Ali A. Ashkar, Lesley A. Reid, and Kenneth L. Rosenthal J. Virol. April 2003 77: 4558-4565; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vivo Replication of an ICP34.5 Second-Site Suppressor Mutant following Corneal Infection Correlates with In Vitro Regulation of eIF2 Phosphorylation Stephen L. Ward, Donalyn Scheuner, Jeremy Poppers, Randal J. Kaufman, Ian Mohr, and David A. Leib J. Virol. April 2003 77: 4626-4634; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Papillomavirus Type 16 L1 Capsomeres Induce L1-Specific Cytotoxic T Lymphocytes and Tumor Regression in C57BL/6 Mice Peter Öhlschläger, Wolfram Osen, Kerstin Dell, Stefan Faath, Robert L. Garcea, Ingrid Jochmus, Martin Müller, Michael Pawlita, Klaus Schäfer, Peter Sehr, Caroline Staib, Gerd Sutter, and Lutz Gissmann J. Virol. April 2003 77: 4635-4645; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Control of Central Nervous System Viral Persistence by Neutralizing Antibody Chandran Ramakrishna, Cornelia C. Bergmann, Roscoe Atkinson, and Stephen A. Stohlman J. Virol. April 2003 77: 4670-4678; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Global Dysfunction of CD4 T-Lymphocyte Cytokine Expression in Simian-Human Immunodeficiency Virus/SIV-Infected Monkeys Is Prevented by Vaccination Paul F. McKay, Dan H. Barouch, Jörn E. Schmitz, Ronald S. Veazey, Darci A. Gorgone, Michelle A. Lifton, Kenneth C. Williams, and Norman L. Letvin J. Virol. April 2003 77: 4695-4702; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Kinetics of CD4+ and CD8+ Memory T-Cell Responses during Hepatitis C Virus Rechallenge of Previously Recovered Chimpanzees Michelina Nascimbeni, Eishiro Mizukoshi, Markus Bosmann, Marian E. Major, Kathleen Mihalik, Charles M. Rice, Stephen M. Feinstone, and Barbara Rehermann J. Virol. April 2003 77: 4781-4793; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Infection of Cattle with a Bovine Herpesvirus 1 Strain That Contains a Mutation in the Latency-Related Gene Leads to Increased Apoptosis in Trigeminal Ganglia during the Transition from Acute Infection to Latency Luciane Lovato, Melissa Inman, Gail Henderson, Alan Doster, and Clinton Jones J. Virol. April 2003 77: 4848-4857; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment E. John Wherry, Joseph N. Blattman, Kaja Murali-Krishna, Robbert van der Most, and Rafi Ahmed J. Virol. April 2003 77: 4911-4927; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Resting CD4+ T Lymphocytes but Not Thymocytes Provide a Latent Viral Reservoir in a Simian Immunodeficiency Virus-Macaca nemestrina Model of Human Immunodeficiency Virus Type 1-Infected Patients on Highly Active Antiretroviral Therapy Anding Shen, M. Christine Zink, Joseph L. Mankowski, Karen Chadwick, Joseph B. Margolick, Lucy M. Carruth, Ming Li, Janice E. Clements, and Robert F. Siliciano J. Virol. April 2003 77: 4938-4949; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Varicella-Zoster Virus Productively Infects Mature Dendritic Cells and Alters Their Immune Function Gavin Morrow, Barry Slobedman, Anthony L. Cunningham, and Allison Abendroth J. Virol. April 2003 77: 4950-4959; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Moloney Murine Leukemia Virus-Based Retrovirus with 4070A Long Terminal Repeat Sequences Induces a High Incidence of Myeloid as Well as Lymphoid Neoplasms Linda Wolff, Richard Koller, Xinrong Hu, and Miriam R. Anver J. Virol. April 2003 77: 4965-4971; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Murine Coronavirus-Induced Hepatitis: JHM Genetic Background Eliminates A59 Spike-Determined Hepatotropism Sonia Navas and Susan R. Weiss J. Virol. April 2003 77: 4972-4978; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Corticosteroids Are Unable To Protect against Pseudorabies Virus-Induced Tissue Damage in the Developing Brain Amanda C. Clase and Bruce W. Banfield J. Virol. April 2003 77: 4979-4984; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Vigorous but Short-Term Gamma Interferon T-Cell Responses against a Dominant HLA-A*02-Restricted Measles Virus Epitope in Patients with Measles Assan Jaye, Carla A. Herberts, Sabelle Jallow, Sowsan Atabani, Michel R. Klein, Peter Hoogerhout, Michael Kidd, Cécile A. C. M. van Els, and Hilton C. Whittle J. Virol. April 2003 77: 5014-5016; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Novel Antiviral Intervention Results in More Accurate Assessment of Human Immunodeficiency Virus Type 1 Replication Dynamics and T-Cell Decay In Vivo Martin Markowitz, Michael Louie, Arlene Hurley, Eugene Sun, Michele Di Mascio, Alan S. Perelson, and David D. Ho J. Virol. April 2003 77: 5037-5038; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Recombination and Evolution:

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Switching Species Tropism: an Effective Way To Manipulate the Feline Coronavirus Genome Bert Jan Haijema, Haukeliene Volders, and Peter J. M. Rottier J. Virol. April 2003 77: 4528-4538; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Immunodeficiency Virus Type 1 Genetic Recombination Is More Frequent Than That of Moloney Murine Leukemia Virus despite Similar Template Switching Rates Adewunmi Onafuwa, Wenfeng An, Nicole D. Robson, and Alice Telesnitsky J. Virol. April 2003 77: 4577-4587; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Template Dimerization Promotes an Acceptor Invasion-Induced Transfer Mechanism during Human Immunodeficiency Virus Type 1 Minus-Strand Synthesis Mini Balakrishnan, Bernard P. Roques, Philip J. Fay, and Robert A. Bambara J. Virol. April 2003 77: 4710-4721; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization and Comparison of Recombinant Simian Immunodeficiency Virus from Drill (Mandrillus leucophaeus) and Mandrill (Mandrillus sphinx) Isolates Jinjie Hu, William M. Switzer, Brian T. Foley, David L. Robertson, Robert M. Goeken, Bette T. Korber, Vanessa M. Hirsch, and Brigitte E. Beer J. Virol. April 2003 77: 4867-4880; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Structure and Assembly:

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Homo-Oligomerization of the Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein and the Role of Disulfide Linkages Sarah K. Wootton and Dongwan Yoo J. Virol. April 2003 77: 4546-4557; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Small Envelope Protein E Is Not Essential for Murine Coronavirus Replication Lili Kuo and Paul S. Masters J. Virol. April 2003 77: 4597-4608; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interactions between Papillomavirus L1 and L2 Capsid Proteins Renée L. Finnen, Kimberly D. Erickson, Xiaojiang S. Chen, and Robert L. Garcea J. Virol. April 2003 77: 4818-4826; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Complexes of Poliovirus Serotypes with Their Common Cellular Receptor, CD155 Yongning He, Steffen Mueller, Paul R. Chipman, Carol M. Bator, Xiaozhong Peng, Valorie D. Bowman, Suchetana Mukhopadhyay, Eckard Wimmer, Richard J. Kuhn, and Michael G. Rossmann J. Virol. April 2003 77: 4827-4835; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Membrane Association of VP22, a Herpes Simplex Virus Type 1 Tegument Protein Michael J. Brignati, Joshua S. Loomis, John W. Wills, and Richard J. Courtney J. Virol. April 2003 77: 4888-4898; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Transformation and Oncogenesis:

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The Extreme Carboxyl Terminus of v-Abl Is Required for Lymphoid Cell Transformation by Abelson Virus David Warren, Deborah S. Griffin, Celine Mainville, and Naomi Rosenberg J. Virol. April 2003 77: 4617-4625; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Vaccines and Antiviral Agents:

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Heat-Aggregated Noninfectious Influenza Virus Induces a More Balanced CD8+-T-Lymphocyte Immunodominance Hierarchy Than Infectious Virus Yunjung Cho, Sameh Basta, Weisan Chen, Jack R. Bennink, and Jonathan W. Yewdell J. Virol. April 2003 77: 4679-4684; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Translational Compensation of a Frameshift Mutation Affecting Herpes Simplex Virus Thymidine Kinase Is Sufficient To Permit Reactivation from Latency Anthony Griffiths, Shun-Hua Chen, Brian C. Horsburgh, and Donald M. Coen J. Virol. April 2003 77: 4703-4709; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutation Patterns and Structural Correlates in Human Immunodeficiency Virus Type 1 Protease following Different Protease Inhibitor Treatments Thomas D. Wu, Celia A. Schiffer, Matthew J. Gonzales, Jonathan Taylor, Rami Kantor, Sunwen Chou, Dennis Israelski, Andrew R. Zolopa, W. Jeffrey Fessel, and Robert W. Shafer J. Virol. April 2003 77: 4836-4847; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Gene Therapy:

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Impact of the Central Polypurine Tract on the Kinetics of Human Immunodeficiency Virus Type 1 Vector Transduction Bénédicte Van Maele, Jan De Rijck, Erik De Clercq, and Zeger Debyser J. Virol. April 2003 77: 4685-4694; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Consequences of DNA-Dependent Protein Kinase Catalytic Subunit Deficiency on Recombinant Adeno-Associated Virus Genome Circularization and Heterodimerization in Muscle Tissue Dongsheng Duan, Yongping Yue, and John F. Engelhardt J. Virol. April 2003 77: 4751-4759; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.