Cover photograph (Copyright © 2003, American Society for Microbiology. All Rights Reserved.): Close-up view of the surface of the complex between human rhinovirus serotype 2 and a soluble fragment of its cellular receptor, the very-low-density lipoprotein receptor (VLDL-R). The individual 5-kDa ligand binding repeats of the VLDL-R are resolved and are seen bound to an annulus on the dome at the fivefold axes. Two such domes, viewed at different angles, are visible. This structure was obtained by cryo-electron microscopy and 3D reconstruction. (See related article in August 2003: vol. 77, no. 15, p. 8504.)