Cover photograph (Copyright © 2002, American Society for Microbiology. All Rights Reserved.): Immunofluorescence image of human rectum, showing distribution of cells expressing DC-SIGN (green) and CCR5 (red). The double-positive cells near the lumen of the rectum (toward the bottom of the figure) represent dendritic cells that express the human immunodeficiency virus adhesion molecule DC-SIGN and viral coreceptor CCR5. Nucleus is stained with DAPI (blue-purple). (See related article in February 2002: vol. 76, issue 4, p. 1866.)