Cover photograph (Copyright © 2002, American Society for Microbiology. All Rights Reserved.): Rocket-shaped crystals of the equine infectious anemia virus matrix protein from which the structure, shown centrally, was determined by using X-ray crystallography. The structure exhibits a high degree of similarity to the matrix proteins of the human and simian immunodeficiency viruses, despite their lack of sequence similarity, but does not associate as a trimer in these crystals. (See related article in February 2002: vol. 76, issue 4, p. 1876.)
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