Cover photograph (Copyright © 2002, American Society for Microbiology. All Rights Reserved.): Composite of confocal micrographs of two varicella-zoster virus (VZV)-induced syncytia. The cells in the syncytium at the upper left have been infected with a VZV ORF47-null mutant; the trans-Golgi network (red) is devoid of VZV glycoprotein E (gE) (green), which is localized primarily to the plasma membrane. In contrast, as shown in the syncytium at the lower right, much of the gE in cells infected with wild-type VZV is localized to the trans-Golgi network. (See related article on page 10980.)
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