About This Cover Other Issues

Contents: January 2000, Volume 74, Issue 2        Virus-Cell Interactions        Recombination and Evolution        Replication        Vaccines and Antiviral Agents        Pathogenesis and Immunity        Gene Therapy        Transformation and Oncogenesis        Structure and Assembly

Table of Contents

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

---

Virus-Cell Interactions:

---

The VP5 Domain of VP4 Can Mediate Attachment of Rotaviruses to Cells Selene Zárate, Rafaela Espinosa, Pedro Romero, Ernesto Méndez, Carlos F. Arias, and Susana López J. Virol. January 2000 74: 593-599; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cell Cycle-Regulated Transcription by the Human Immunodeficiency Virus Type 1 Tat Transactivator Fatah Kashanchi, Emmanuel T. Agbottah, Cynthia A. Pise-Masison, Renaud Mahieux, Janet Duvall, Ajit Kumar, and John N. Brady J. Virol. January 2000 74: 652-660; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Anti-Feline Immunodeficiency Virus (FIV) Soluble Factor(s) Produced from Antigen-Stimulated Feline CD8+ T Lymphocytes Suppresses FIV Replication In-Soo Choi, Regina Hokanson, and Ellen W. Collisson J. Virol. January 2000 74: 676-683; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Determinants of Syncytium Formation in Microglia by Human Immunodeficiency Virus Type 1: Role of the V1/V2 Domains Joseph T. C. Shieh, Julio Martín, Gordon Baltuch, Michael H. Malim, and Francisco González-Scarano J. Virol. January 2000 74: 693-701; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Functional Characterization of Intracellular and Secreted Forms of a Truncated Hepatitis C Virus E2 Glycoprotein Mike Flint, Jean Dubuisson, Catherine Maidens, Richard Harrop, Geoffrey R. Guile, Persephone Borrow, and Jane A. McKeating J. Virol. January 2000 74: 702-709; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Histone Acetylation and Reactivation of Epstein-Barr Virus from Latency Peter J. Jenkins, Ulrich K. Binné, and Paul J. Farrell J. Virol. January 2000 74: 710-720; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Glial Cell-Specific Regulation of the JC Virus Early Promoter by Large T Antigen Hee-Sun Kim, Nuno M. Goncalves, and John W. Henson J. Virol. January 2000 74: 755-763; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of a Second Transforming Function in Bovine Papillomavirus Type 1 E6 and the Role of E6 Interactions with Paxillin, E6BP, and E6AP Kingshuk Das, Joanna Bohl, and Scott B. Vande Pol J. Virol. January 2000 74: 812-816; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

pRB-Dependent, J Domain-Independent Function of Simian Virus 40 Large T Antigen in Override of p53 Growth Suppression Ole Gjoerup, Herta Chao, James A. DeCaprio, and Thomas M. Roberts J. Virol. January 2000 74: 864-874; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Potential Role for Luman, the Cellular Homologue of Herpes Simplex Virus VP16 ( Gene trans-Inducing Factor), in Herpesvirus Latency Rui Lu and Vikram Misra J. Virol. January 2000 74: 934-943; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Human Milk Factor Susceptible to Cathepsin D Inhibitors Enhances Human Immunodeficiency Virus Type 1 Infectivity and Allows Virus Entry into a Mammary Epithelial Cell Line Kamal El Messaoudi, Lise F. Thiry, Corinne Liesnard, Nicole Van Tieghem, Alex Bollen, and Nicole Moguilevsky J. Virol. January 2000 74: 1004-1007; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Human Herpesvirus 8 Homolog of Epstein-Barr Virus SM Protein (KS-SM) Is a Posttranscriptional Activator of Gene Expression Ashish K. Gupta, Vivian Ruvolo, Cam Patterson, and Sankar Swaminathan J. Virol. January 2000 74: 1038-1044; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Late Lytic LMP-1 Protein of Epstein-Barr Virus Can Negatively Regulate LMP-1 Signaling Kimberly D. Erickson and Jennifer M. Martin J. Virol. January 2000 74: 1057-1060; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Recombination and Evolution:

---

Mutations of the Kissing-Loop Dimerization Sequence Influence the Site Specificity of Murine Leukemia Virus Recombination In Vivo Jacob Giehm Mikkelsen, Anders H. Lund, Mogens Duch, and Finn Skou Pedersen J. Virol. January 2000 74: 600-610; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Widespread Distribution of a Group I Intron and Its Three Deletion Derivatives in the Lysin Gene of Streptococcus thermophilus Bacteriophages Sophie Foley, Anne Bruttin, and Harald Brüssow J. Virol. January 2000 74: 611-618; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Nucleotide and Amino Acid Complexity of Hepatitis C Virus Quasispecies in Serum and Liver Beatriz Cabot, María Martell, Juan I. Esteban, Sílvia Sauleda, Teresa Otero, Rafael Esteban, Jaime Guàrdia, and Jordi Gómez J. Virol. January 2000 74: 805-811; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Primary Structure of the Herpesvirus Ateles Genome Jens-Christian Albrecht J. Virol. January 2000 74: 1033-1037; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Replication:

---

A Putative G Protein-Coupled Receptor, RDC1, Is a Novel Coreceptor for Human and Simian Immunodeficiency Viruses Nobuaki Shimizu, Yasushi Soda, Katsuaki Kanbe, Hui-yu Liu, Ryozaburo Mukai, Toshio Kitamura, and Hiroo Hoshino J. Virol. January 2000 74: 619-626; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Profilin Is Required for Optimal Actin-Dependent Transcription of Respiratory Syncytial Virus Genome RNA Emily Burke, Nicole M. Mahoney, Steven C. Almo, and Sailen Barik J. Virol. January 2000 74: 669-675; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Role for Single-Stranded Templates in Cell-Free Adeno-Associated Virus DNA Replication Peter Ward and R. Michael Linden J. Virol. January 2000 74: 744-754; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Nuclear Export Signal within the E4orf6 Protein of Adenovirus Type 5 Supports Virus Replication and Cytoplasmic Accumulation of Viral mRNA Silke Weigel and Matthias Dobbelstein J. Virol. January 2000 74: 764-772; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutational Analysis of the GB Virus B Internal Ribosome Entry Site René Rijnbrand, Geoffrey Abell, and Stanley M. Lemon J. Virol. January 2000 74: 773-783; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Characterization of an Internal Ribosomal Entry Segment in the 5' Leader of Murine Leukemia Virus env RNA Clarence Deffaud and Jean-Luc Darlix J. Virol. January 2000 74: 846-850; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

De Novo Initiation of RNA Synthesis by the RNA-Dependent RNA Polymerase (NS5B) of Hepatitis C Virus Guangxiang Luo, Robert K. Hamatake, Danielle M. Mathis, Jason Racela, Karen L. Rigat, Julie Lemm, and Richard J. Colonno J. Virol. January 2000 74: 851-863; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interactions between Equine Cyclin T1, Tat, and TAR Are Disrupted by a Leucine-to-Valine Substitution Found in Human Cyclin T1 Ran Taube, Koh Fujinaga, Dan Irwin, Jörg Wimmer, Matthias Geyer, and B. Matija Peterlin J. Virol. January 2000 74: 892-898; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Second-Site Changes Affect Viability of Amphotropic/Ecotropic Chimeric Enveloped Murine Leukemia Viruses Lucille O'Reilly and Monica J. Roth J. Virol. January 2000 74: 899-913; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Expression of the Totivirus Helminthosporium victoriae 190S Virus RNA-Dependent RNA Polymerase from Its Downstream Open Reading Frame in Dicistronic Constructs Ana I. Soldevila and Said A. Ghabrial J. Virol. January 2000 74: 997-1003; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Vaccines and Antiviral Agents:

---

A Recombinant Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Complex Stabilized by an Intermolecular Disulfide Bond between the gp120 and gp41 Subunits Is an Antigenic Mimic of the Trimeric Virion-Associated Structure James M. Binley, Rogier W. Sanders, Brian Clas, Norbert Schuelke, Aditi Master, Yong Guo, Francis Kajumo, Deborah J. Anselma, Paul J. Maddon, William C. Olson, and John P. Moore J. Virol. January 2000 74: 627-643; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Herpesvirus 8 Open Reading Frame 21 Is a Thymidine and Thymidylate Kinase of Narrow Substrate Specificity That Efficiently Phosphorylates Zidovudine but Not Ganciclovir Erik A. Gustafson, Raymond F. Schinazi, and Joyce D. Fingeroth J. Virol. January 2000 74: 684-692; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

High-Level Resistance to 3'-Azido-3'-Deoxythimidine due to a Deletion in the Reverse Transcriptase Gene of Human Immunodeficiency Virus Type 1 Tomozumi Imamichi, Tanima Sinha, Hiromi Imamichi, Yi-Ming Zhang, Julie A. Metcalf, Judith Falloon, and H. Clifford Lane J. Virol. January 2000 74: 1023-1028; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Pathogenesis and Immunity:

---

Large-Plaque Mutants of Sindbis Virus Show Reduced Binding to Heparan Sulfate, Heightened Viremia, and Slower Clearance from the Circulation Andrew P. Byrnes and Diane E. Griffin J. Virol. January 2000 74: 644-651; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Heterogeneity of Hypervariable Region 1 of the Hepatitis C Virus (HCV) Genome and Sensitivity of HCV to Alpha Interferon Therapy K. Sandres, M. Dubois, C. Pasquier, J. L. Payen, L. Alric, M. Duffaut, J. P. Vinel, J. P. Pascal, J. Puel, and J. Izopet J. Virol. January 2000 74: 661-668; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mapping of Genetic Determinants of Rubella Virus Associated with Growth in Joint Tissue Karen D. Lund and Janet K. Chantler J. Virol. January 2000 74: 796-804; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pseudorabies Virus Expressing Bovine Herpesvirus 1 Glycoprotein B Exhibits Altered Neurotropism and Increased Neurovirulence Volker Gerdts, Jörg Beyer, Béla Lomniczi, and Thomas C. Mettenleiter J. Virol. January 2000 74: 817-827; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Entry versus Blockade of Brain Infection following Oral or Intraperitoneal Scrapie Administration: Role of Prion Protein Expression in Peripheral Nerves and Spleen Richard Race, Michael Oldstone, and Bruce Chesebro J. Virol. January 2000 74: 828-833; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of Pseudorabies Virus Us9, a Type II Membrane Protein, in Infection of Tissue Culture Cells and the Rat Nervous System A. D. Brideau, J. P. Card, and L. W. Enquist J. Virol. January 2000 74: 834-845; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of Dendritic Cell Targeting in Venezuelan Equine Encephalitis Virus Pathogenesis Gene H. MacDonald and Robert E. Johnston J. Virol. January 2000 74: 914-922; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Biology of Attenuated Modified Vaccinia Virus Ankara Recombinant Vector in Mice: Virus Fate and Activation of B- and T-Cell Immune Responses in Comparison with the Western Reserve Strain and Advantages as a Vaccine Juan C. Ramírez, M. Magdalena Gherardi, and Mariano Esteban J. Virol. January 2000 74: 923-933; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Situ Distribution of Hepatitis C Virus Replicative-Intermediate RNA in Hepatic Tissue and Its Correlation with Liver Disease Ming Chang, Anthony P. Marquardt, Brent L. Wood, Ocean Williams, Scott J. Cotler, Shari L. Taylor, Robert L. Carithers, Jr., and David R. Gretch J. Virol. January 2000 74: 944-955; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Replication of Herpes Simplex Virus Type 1 within Trigeminal Ganglia Is Required for High Frequency but Not High Viral Genome Copy Number Latency Richard L. Thompson and N. M. Sawtell J. Virol. January 2000 74: 965-974; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Determinants of Altered Virulence of Taiwanese Foot-and-Mouth Disease Virus Clayton W. Beard and Peter W. Mason J. Virol. January 2000 74: 987-991; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Uneven Distribution of Hepatitis C Virus Quasispecies in Tissues from Subjects with End-Stage Liver Disease: Confounding Effect of Viral Adsorption and Mounting Evidence for the Presence of Low-Level Extrahepatic Replication Tomasz Laskus, Marek Radkowski, Lian-Fu Wang, Marek Nowicki, and Jorge Rakela J. Virol. January 2000 74: 1014-1017; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Immunodeficiency Virus Type 1- and Cytomegalovirus-Specific Cytotoxic T Lymphocytes Can Persist at High Frequency for Prolonged Periods in the Absence of Circulating Peripheral CD4+ T Cells Hans M. L. Spiegel, Graham S. Ogg, Elizabeth DeFalcon, Megan E. Sheehy, Simon Monard, Patrick A. J. Haslett, Geraldine Gillespie, Sean M. Donahoe, Henry Pollack, William Borkowsky, Andrew J. McMichael, and Douglas F. Nixon J. Virol. January 2000 74: 1018-1022; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Granzyme A, a Noncytolytic Component of CD8+ Cell Granules, Restricts the Spread of Herpes Simplex Virus in the Peripheral Nervous Systems of Experimentally Infected Mice Rosemarie A. Pereira, Markus M. Simon, and Anthony Simmons J. Virol. January 2000 74: 1029-1032; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The r144 Major Histocompatibility Complex Class I-Like Gene of Rat Cytomegalovirus Is Dispensable for both Acute and Long-Term Infection in the Immunocompromised Host Patrick S. Beisser, Jeroen S. Kloover, Gert E. L. M. Grauls, Marinus J. Blok, Cathrien A. Bruggeman, and Cornelis Vink J. Virol. January 2000 74: 1045-1050; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Gene Therapy:

---

Nuclear Import of Moloney Murine Leukemia Virus DNA Mediated by Adenovirus Preterminal Protein Is Not Sufficient for Efficient Retroviral Transduction in Nondividing Cells André Lieber, Mark A. Kay, and Zong-Yi Li J. Virol. January 2000 74: 721-734; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Long-Term Transgene Expression in Mice Infected with a Herpes Simplex Virus Type 1 Mutant Severely Impaired for Immediate-Early Gene Expression Ker R. Marshall, Robin H. Lachmann, Stacey Efstathiou, Angela Rinaldi, and Chris M. Preston J. Virol. January 2000 74: 956-964; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Impaired Intracellular Trafficking of Adeno-Associated Virus Type 2 Vectors Limits Efficient Transduction of Murine Fibroblasts Jonathan Hansen, Keyun Qing, Hyung-Joo Kwon, Cathryn Mah, and Arun Srivastava J. Virol. January 2000 74: 992-996; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Evaluation of VP22 Spread in Tissue Culture Neil Brewis, Anne Phelan, Jeanette Webb, Jeff Drew, Gill Elliott, and Peter O'Hare J. Virol. January 2000 74: 1051-1056; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Transformation and Oncogenesis:

---

Epstein-Barr Virus Recombinants from BC-1 and BC-2 Can Immortalize Human Primary B Lymphocytes with Different Levels of Efficiency and in the Absence of Coinfection by Kaposi's Sarcoma-Associated Herpesvirus Andrew J. Aguirre and Erle S. Robertson J. Virol. January 2000 74: 735-743; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

LMP1 of Epstein-Barr Virus Induces Proliferation of Primary Mouse Embryonic Fibroblasts and Cooperatively Transforms the Cells with a p16-Insensitive CDK4 Oncogene Xinhai Yang, Jonathan S. T. Sham, M. H. Ng, Sai-Wah Tsao, Dekai Zhang, Scott W. Lowe, and Liang Cao J. Virol. January 2000 74: 883-891; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Isolation of Transformation Suppressor Genes by cDNA Subtraction: Lumican Suppresses Transformation Induced by v-src and v-K-ras Naohisa Yoshioka, Hirokazu Inoue, Kazuyoshi Nakanishi, Kiyomasa Oka, Masuo Yutsudo, Atsuko Yamashita, Akira Hakura, and Hiroshi Nojima J. Virol. January 2000 74: 1008-1013; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

---

Structure and Assembly:

---

A Cell-Line-Specific Defect in the Intracellular Transport and Release of Assembled Retroviral Capsids Scott D. Parker and Eric Hunter J. Virol. January 2000 74: 784-795; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Leader Polypeptide of Theiler's Murine Encephalomyelitis Virus Is Required for the Assembly of Virions in Mouse L Cells Cyrus Badshah, Miriam A. Calenoff, and Kathleen Rundell J. Virol. January 2000 74: 875-882; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Accumulation of Virion Tegument and Envelope Proteins in a Stable Cytoplasmic Compartment during Human Cytomegalovirus Replication: Characterization of a Potential Site of Virus Assembly Veronica Sanchez, Kenneth D. Greis, Elizabeth Sztul, and William J. Britt J. Virol. January 2000 74: 975-986; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.